公开(公告)号：US20190240118A1

公开(公告)日：2019-08-08

申请号：US16389232

申请日：2019-04-19

Applicant: DENTSPLY SIRONA Inc.

Inventor： Christos ANGELETAKIS

IPC: A61K6/10 ,  C08K3/36 ,  C08K5/06 ,  A61K6/00 ,  C08L83/04 ,  C08L83/12

CPC classification number: A61K6/10 ,  A61K6/0047 ,  C08K3/36 ,  C08K5/06 ,  C08L83/04 ,  C08L83/12 ,  C08L51/085 ,  C08L83/00

Abstract: Disclosed herein is a dental impression material that includes a two part addition curing silicone composition. The disclosed impression material contains a surfactant system composed of a fluorosurfactant and a fatty alcohol ethoxylate. The impression material disclosed herein exhibits improved storage stability than known systems using fluorosurfactants and silicone ether compounds.

公开(公告)号：US09937106B2

公开(公告)日：2018-04-10

申请号：US15292599

申请日：2016-10-13

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Christoph Thalacker ,  Karsten Dede ,  Alexandra Glaser ,  Thomas Luchterhandt ,  Markus Watermann

IPC: A61K6/08 ,  A61K6/083 ,  A61K6/00 ,  A61C19/00 ,  A61C5/30 ,  A61K6/087 ,  A61C7/16 ,  A61C13/271 ,  A61C5/50 ,  A61C5/70

CPC classification number: A61K6/0835 ,  A61C5/30 ,  A61C5/50 ,  A61C5/70 ,  A61C7/16 ,  A61C13/26 ,  A61C19/00 ,  A61C19/005 ,  A61K6/0017 ,  A61K6/0023 ,  A61K6/0047 ,  A61K6/083 ,  A61K6/087 ,  C08L33/00 ,  C08L63/00

Abstract: The invention relates to a kit of parts comprising part A and part B, part A comprising a polymerizable component having an acid group in the molecule, an initiator, part B comprising an activator, and a film former with a molecular weight of at least 1000.The invention also relates to a composition obtainable by mixing the components contained in the kit of parts and to a process for producing the kit of parts comprising the steps of bringing the components contained in part B of the kit in contact with a surface, drying the surface to form a film.

公开(公告)号：US20180064613A1

公开(公告)日：2018-03-08

申请号：US15707742

申请日：2017-09-18

Applicant: South Dakota Board of Regents

Inventor： Grigoriy Sereda ,  Joshua Brower

IPC: A61K6/00 ,  A61Q11/00 ,  A61K8/34 ,  A23G4/06 ,  A61C19/06 ,  A61C19/08 ,  A61K8/73 ,  A61K8/60 ,  A61K8/365 ,  A61K8/29 ,  A61K8/26 ,  A61K8/25 ,  A61K8/24 ,  A61K8/11 ,  A61K8/02

CPC classification number: A61K6/0047 ,  A23G4/06 ,  A23G4/064 ,  A61C5/62 ,  A61C19/063 ,  A61C19/08 ,  A61K6/0008 ,  A61K6/007 ,  A61K8/0241 ,  A61K8/11 ,  A61K8/24 ,  A61K8/25 ,  A61K8/26 ,  A61K8/29 ,  A61K8/347 ,  A61K8/365 ,  A61K8/604 ,  A61K8/733 ,  A61K8/735 ,  A61K8/736 ,  A61K2800/28 ,  A61K2800/412 ,  A61K2800/413 ,  A61K2800/612 ,  A61K2800/884 ,  A61K2800/92 ,  A61Q11/00

Abstract: The present invention relates to a method of remineralizing and desensitizing teeth utilizing the sequential steps of first applying to the teeth a first component that attaches to the teeth and secondly applying to the teeth treated with the first component a second component that attaches to the first component.

公开(公告)号：US09642780B2

公开(公告)日：2017-05-09

申请号：US14125714

申请日：2012-06-15

Applicant: Ulrica Almhöjd ,  Åke Nilsson

Inventor： Ulrica Almhöjd ,  Åke Nilsson

IPC: A61Q11/00 ,  A61K6/00 ,  A61K8/41 ,  A61K8/20 ,  A61K8/22

CPC classification number: A61K6/0047 ,  A61K6/002 ,  A61K6/0061 ,  A61K6/0067 ,  A61K6/007 ,  C08L1/286

Abstract: The present invention relates to a kit of parts for detection and removal of carious dentin tissue comprising: (i) one or more compounds being a hydrazine derivative, and (ii) means for chemical treatment of carious dentin tissue. Further, the invention concerns a preparation containing an active, caries-dissolving two-component liquid in the form of a first active, caries-dissolving component and a second component which reduces the aggressiveness of the active component to mucous membranes, a viscosity increasing substance and one or more compounds being a hydrazine derivative. The hydrazine derivative labels carious dentin tissue selectively and substantially irreversibly in the presence of healthy dentin tissue, which is useful in the context of caries removal.

公开(公告)号：US20160374904A1

公开(公告)日：2016-12-29

申请号：US15189228

申请日：2016-06-22

Applicant: South Dakota Board of Regents

Inventor： Grigoriy Sereda

IPC: A61K6/00 ,  A61K8/58 ,  A61K8/19 ,  A61K8/73 ,  A61K8/24 ,  A61C15/04 ,  A61K8/34 ,  A61K8/365 ,  A61K8/29 ,  A61K8/26 ,  A61C15/02 ,  A61Q11/00 ,  A61K8/72

CPC classification number: A61K6/0047 ,  A23G4/06 ,  A23G4/064 ,  A61C5/62 ,  A61C19/063 ,  A61C19/08 ,  A61K6/0008 ,  A61K6/007 ,  A61K8/0241 ,  A61K8/11 ,  A61K8/24 ,  A61K8/25 ,  A61K8/26 ,  A61K8/29 ,  A61K8/347 ,  A61K8/365 ,  A61K8/604 ,  A61K8/733 ,  A61K8/735 ,  A61K8/736 ,  A61K2800/28 ,  A61K2800/412 ,  A61K2800/413 ,  A61K2800/612 ,  A61K2800/884 ,  A61K2800/92 ,  A61Q11/00

Abstract: The present invention relates to a method of remineralizing and desensitizing teeth utilizing the sequential steps of first applying to the teeth a first component that attaches to the teeth and secondly applying to the teeth treated with the first component a second component that attaches to the first component.

Abstract translation: 本发明涉及一种再矿化和脱敏牙齿的方法，其中使用顺序步骤，首先向牙齿施加附着到牙齿上的第一部件，其次施加到用第一部件处理的牙齿附着到第一部件上的第二部件 。

公开(公告)号：US20160324728A1

公开(公告)日：2016-11-10

申请号：US15111847

申请日：2015-01-19

Applicant: STRAUMANN HOLDING AG

Inventor： Alessandra Apicella ,  Peggy Heunemann

IPC: A61K6/00 ,  A61K38/17 ,  A61K47/48 ,  A61K47/18 ,  A61Q11/00 ,  A61K8/64 ,  A61K8/73 ,  A61K8/36 ,  A61K8/44 ,  A61K35/32 ,  A61K6/027

CPC classification number: A61K6/0038 ,  A61K6/0041 ,  A61K6/0047 ,  A61K6/0067 ,  A61K6/027 ,  A61K8/36 ,  A61K8/44 ,  A61K8/64 ,  A61K8/733 ,  A61K8/735 ,  A61K35/32 ,  A61K38/17 ,  A61K47/183 ,  A61K47/61 ,  A61K2800/52 ,  A61K2800/591 ,  A61K2800/60 ,  A61K2800/805 ,  A61K2800/84 ,  A61Q11/00

Abstract: The present invention relates to a process for producing a pharmaceutical, dental and/or cosmetic formulation comprising purified enamel matrix proteins and/or enamel matrix derivative (EMD) proteins, which is heat stable. In particular, the present invention is related to a process for producing stable formulations of enamel matrix proteins and/or enamel matrix derivative (EMD) proteins, wherein said proteins and/or derivatives are solved in a low pH formulation before being subjected to a heat-treatment step.

Abstract translation: 本发明涉及一种制备药物，牙科和/或化妆品制剂的方法，其包含热稳定的纯化的釉质基质蛋白质和/或釉质基质衍生物（EMD）蛋白质。 特别地，本发明涉及一种用于生产釉质基质蛋白质和/或釉质基质衍生物（EMD）蛋白质的稳定制剂的方法，其中所述蛋白质和/或衍生物在经受热量之前溶解在低pH制剂中 处理步骤。

公开(公告)号：US09427380B2

公开(公告)日：2016-08-30

申请号：US14346614

申请日：2012-09-21

Applicant: SEPTODONT OU SEPTODONT SAS OU SPECIALITES SEPTODONT

Inventor： Gilles Richard ,  Olivier Marie ,  Laurianne Bafounguissa

IPC: A61K6/00 ,  A61K6/06 ,  A61C19/00 ,  C04B14/30 ,  C04B14/38 ,  C04B14/26 ,  C04B22/06 ,  C04B7/345 ,  C04B16/08 ,  C04B16/06 ,  C04B16/00

CPC classification number: A61K6/0047 ,  A61K6/0073 ,  A61K6/0091 ,  A61K6/0612 ,  C04B7/345 ,  C04B14/26 ,  C04B14/301 ,  C04B14/38 ,  C04B16/00 ,  C04B16/06 ,  C04B16/08 ,  C04B22/064

Abstract: The present invention relates to a solid composition comprising: a calcium silicate powder, a set accelerator in the form of a powder, a reinforcing filler in a solid form, a radio-opacifying agent in a solid form, at least one complementary ingredient selected from solid fibers or solid porous fillers, optionally a water-reducing agent in a solid form, and optionally solid pigments. The present invention also relates to a kit of parts for the preparation of a composition suitable for use in dentistry comprising in a first container a solid phase including the solid composition according to the invention, and in a second container an aqueous phase. The present invention also relates to a kit of parts for the preparation of a composition suitable for use in dentistry comprising a container, said container comprising at least two cells, the first cell comprising a solid phase including the solid composition of the invention and the second cell comprising an aqueous phase. The present invention also relates to a method for preparing a dental cement, including mixing the solid composition of the invention with an aqueous phase and to resulting dental cement.

Abstract translation: 固体组合物本发明涉及一种固体组合物，其包括：硅酸钙粉末，粉末形式的凝固加速剂，固体形式的增强填料，固体形式的放射性不透明剂，至少一种互补成分，选自 固体纤维或固体多孔填料，任选的固体形式的减水剂，以及任选的固体颜料。 本发明还涉及一种用于制备适用于牙科的组合物的试剂盒，其包括在第一容器中，包含根据本发明的固体组合物的固相和在第二容器中的水相。 本发明还涉及一种用于制备适用于牙科的组合物的试剂盒，其包含容器，所述容器包含至少两个细胞，所述第一细胞包含固相，其包含本发明的固体组合物和第二 包含水相的细胞。 本发明还涉及一种制备牙科粘固剂的方法，包括将本发明的固体组合物与水相混合，得到牙科粘固剂。

公开(公告)号：US09414995B2

公开(公告)日：2016-08-16

申请号：US14926430

申请日：2015-10-29

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Richard P. Rusin ,  Sumita B. Mitra ,  Kevin M. Cummings

IPC: A61K6/00 ,  A61K6/083 ,  A61K6/02

CPC classification number: A61K6/0082 ,  A61K6/0017 ,  A61K6/0023 ,  A61K6/0029 ,  A61K6/0047 ,  A61K6/0073 ,  A61K6/0088 ,  A61K6/0091 ,  A61K6/0205 ,  A61K6/083 ,  C08L33/00

Abstract: The present application provides dental fillers, and methods of making and using dental fillers that include a treated surface that includes phosphorus and a divalent cation. Dental compositions including such dental fillers can be useful for delivering ions to the oral environment.

公开(公告)号：US09314408B2

公开(公告)日：2016-04-19

申请号：US13757366

申请日：2013-02-01

Applicant: VOCO Gmbh

Inventor： Tobias Blomker ,  Nils Fontein ,  Manfred Stepputtis ,  Manfred Thomas Plaumann

IPC: A61K6/08 ,  A61K6/00 ,  A61K6/083

CPC classification number: A61K6/0047 ,  A61K6/083

Abstract: The present invention relates to dental polymerizable composite materials (curable dental compositions) comprising one or more plasticizers comprising a tricyclic structural element, to dental materials (polymers), obtainable by curing from the dental polymerizable composite materials comprising one or more plasticizers comprising a tricyclic structural element, to processes for producing a dental material and to dental curable composite materials for use in a therapeutic method in the production of a dental material.

Abstract translation: 本发明涉及包含一种或多种包含三环结构元件的增塑剂的牙科可聚合复合材料（可固化牙科用组合物），可用于通过从包含一种或多种增塑剂的牙科可复合材料固化获得的牙科材料（聚合物），所述增塑剂包括三环结构 元件，用于生产牙科材料的方法和用于牙科材料制造中的治疗方法中的牙科用固化性复合材料。

公开(公告)号：US20160045401A1

公开(公告)日：2016-02-18

申请号：US14926430

申请日：2015-10-29

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Richard P. Rusin ,  Sumita B. Mitra ,  Kevin M. Cummings

IPC: A61K6/00 ,  A61K6/02

CPC classification number: A61K6/0082 ,  A61K6/0017 ,  A61K6/0023 ,  A61K6/0029 ,  A61K6/0047 ,  A61K6/0073 ,  A61K6/0088 ,  A61K6/0091 ,  A61K6/0205 ,  A61K6/083 ,  C08L33/00

Abstract: The present application provides dental fillers, and methods of making and using dental fillers that include a treated surface that includes phosphorus and a divalent cation. Dental compositions including such dental fillers can be useful for delivering ions to the oral environment.

Abstract translation: 本申请提供牙科填料，以及制造和使用包括磷和二价阳离子的处理表面的牙科填料的方法。 包括这种牙科填料的牙科组合物可用于将离子输送到口腔环境中。