公开(公告)号：US5658942A

公开(公告)日：1997-08-19

申请号：US399500

申请日：1995-03-07

Applicant: Masaaki Kurabayashi ,  Hiroshi Kogen ,  Hiroshi Kadokawa ,  Hideshi Kurihara ,  Kazuo Hasegawa ,  Masao Kuroda

Inventor： Masaaki Kurabayashi ,  Hiroshi Kogen ,  Hiroshi Kadokawa ,  Hideshi Kurihara ,  Kazuo Hasegawa ,  Masao Kuroda

IPC: C07C251/44 ,  C07C251/50 ,  C07D295/088 ,  C07D309/30 ,  C07D405/12 ,  C07D407/12 ,  C07D413/12 ,  A61K31/35 ,  A61K31/20 ,  A61K31/42 ,  A61K31/435

CPC classification number: C07D295/088 ,  C07C251/44 ,  C07C251/50 ,  C07D309/30 ,  C07D405/12 ,  C07D407/12 ,  C07D413/10 ,  C07D413/12 ,  C07C2101/14 ,  C07C2102/28

Abstract: Compounds of formula (I): ##STR1## in which: R represents hydrogen, methyl or hydroxy; X represents an alkyl, alkenyl, cycloalkyl, aryl, aralkyl, or heterocyclic group; A represents a single bond, or an alkylene, alkenylene, alkynylene or alkadienylene group; Y represents hydrogen, or an aryl, cycloalkyl or heterocyclic group; have valuable antihypercholesteremic activities and may be used in the treatment of disorders arising from a blood cholesterol imbalance in humans and other animals.

Abstract translation: 式（I）的化合物：其中：R表示氢，甲基或羟基; X表示烷基，烯基，环烷基，芳基，芳烷基或杂环基; A表示单键，或亚烷基，亚烯基，亚炔基或链亚二烯基; Y表示氢，或芳基，环烷基或杂环基; 具有有价值的抗胆固醇活性，可用于治疗由于人类和其他动物的血液胆固醇不平衡引起的疾病。

公开(公告)号：US5360522A

公开(公告)日：1994-11-01

申请号：US54197

申请日：1993-04-30

Applicant: Masao Kuroda ,  Yutaka Sakakibara

Inventor： Masao Kuroda ,  Yutaka Sakakibara

IPC: C02F1/46 ,  C02F1/467 ,  C02F3/00 ,  C02F3/34 ,  C02F9/00 ,  C12Q1/00 ,  C02F1/461

CPC classification number: C02F3/302 ,  C02F3/005 ,  C02F3/34 ,  C12Q1/001 ,  C02F1/4676 ,  C02F2101/163 ,  C02F2101/22

Abstract: An electrode consists of a cathode matrix material and a biocatalyst immobilized on the matrix material. A water under treatment is treated by disposing the electrode as a cathode and an anode opposed thereto in the water, and applying an electric current between the cathode and the anode.

Abstract translation: 电极由阴极基体材料和固定在基质材料上的生物催化剂组成。 处理水是通过在水中设置作为阴极和与其相对的阳极的电极，并在阴极和阳极之间施加电流来处理的。

公开(公告)号：US5272174A

公开(公告)日：1993-12-21

申请号：US919154

申请日：1992-07-23

Applicant: Kouhei Furuya ,  Takao Okazaki ,  Yoshio Tsujita ,  Seigo Iwado ,  Kiyoshi Hamano ,  Masao Kuroda ,  Jun Yoshikawa ,  Toshiaki Iwai ,  Kunio Nakano

Inventor： Kouhei Furuya ,  Takao Okazaki ,  Yoshio Tsujita ,  Seigo Iwado ,  Kiyoshi Hamano ,  Masao Kuroda ,  Jun Yoshikawa ,  Toshiaki Iwai ,  Kunio Nakano

IPC: C07D309/10 ,  C12P7/62 ,  C12P17/06 ,  A61K31/365 ,  A61K31/215

CPC classification number: C12R1/645 ,  C07D309/10 ,  C12P17/06 ,  C12P7/62 ,  C12R1/365 ,  Y10S514/824

Abstract: Derivatives of ML-236B carboxylic acid, its salts and esters and corresponding lactone have a hydroxy group at the 3"-position and optionally also at the 6'-position. These derivatives may be prepared by the enzymatic hydroxylation of a corresponding ML-236B compound employing an enzyme produced by a microorganism of the genus Streptomyces or Amycolata, especially Streptomyces sp. SANK 62285, Streptomyces sp. SANK 62385, Streptomyces sp. SANK 62485, Streptomyces sp. SANK 62585, Amycolata autotrophica SANK 62781. Amycolata autotrophica subsp. canberrica SANK 62882 or Amycolata autotrophica subsp. amethystina SANK 62981. These derivatives have the ability to inhibit cholesterol biosynthesis.

Abstract translation: ML-236B羧酸的衍生物，其盐和酯和相应的内酯在3“位和任选也在6'位具有羟基。 这些衍生物可以通过使用由链霉菌属或Amycolata属的微生物，特别是链霉菌属（Streptomyces sp。）产生的酶的相应的ML-236B化合物的酶促羟基化来制备。 SANK 62285，Streptomyces sp。 SANK 62385，Streptomyces sp。 SANK 62485，Streptomyces sp。 SANK 62585，Amycolata autotrophica SANK 62781. Amycolata autotrophica subsp。 canberrica SANK 62882或Amycolata autotrophica subsp。 紫杉醇SANK 62981.这些衍生物具有抑制胆固醇生物合成的能力。

公开(公告)号：US4099419A

公开(公告)日：1978-07-11

申请号：US773171

申请日：1977-03-01

Applicant: Masao Kuroda ,  Toshio Kondo ,  Toshio Ogawa ,  Sekijyuro Ono

Inventor： Masao Kuroda ,  Toshio Kondo ,  Toshio Ogawa ,  Sekijyuro Ono

IPC: A61B8/14 ,  A61B8/00 ,  G01N29/06 ,  G01N29/24 ,  G01R13/20 ,  G01S7/52 ,  G01N29/00

CPC classification number: G01N29/06 ,  G01S7/52046

Abstract: There is disclosed an ultrasonic tomography apparatus of electronic scanning type in which an array of ultrasonic transducer elements are excited with desired time delays allotted for the transducer elements thereby to transmit and receive ultrasonic beams at a deflection angle corresponding to the desired time delays, and the received echo signal of the ultrasonic beams is displayed on a CRT display device in a form of a tomograph of a sample to which the ultrasonic beams are directed. The apparatus comprises a memory in which both of first signals representative of the time delays given to the transducer elements in dependence on given deflection angles and signals designating display position in the X- and Y-directions of the CRT are previously stored and read out for producing delays allotted for the transducer elements and displaying the received echo signal on the CRT.

Abstract translation: 公开了一种电子扫描型超声波断层摄影装置，其中以期望的时间延迟激励超声波换能器元件阵列，从而以对应于期望的时间延迟的偏转角发送和接收超声波束，并且 超声波束的接收回波信号以超声波束所指向的样本的断层图的形式显示在CRT显示装置上。 该装置包括存储器，其中预先存储表示根据给定偏转角给予换能器元件的时间延迟的两个第一信号和指示CRT的X和Y方向上的显示位置的信号，并读出以供 产生分配给换能器元件的延迟并在CRT上显示所接收的回波信号。

公开(公告)号：US08758258B2

公开(公告)日：2014-06-24

申请号：US12684406

申请日：2010-01-08

Applicant: Yusuke Takahashi ,  Osamu Urano ,  Masao Kuroda

Inventor： Yusuke Takahashi ,  Osamu Urano ,  Masao Kuroda

IPC: A61B5/02

CPC classification number: A61B5/02438 ,  A61B5/0285 ,  A61B5/681 ,  A61B5/721

Abstract: A beat detection device includes: a pulse wave sensor adapted to detect and output a pulse wave signal; a body motion sensor adapted to detect and output a body motion signal due to a body motion of a human body; a pulse wave signal filtering section adapted to generate an adaptive filter based on the body motion signal to extract a noise signal in the pulse wave signal, and to output a beat signal obtained by eliminating the noise signal from the pulse wave signal; and a filter coefficient setting section adapted to set a coefficient of the adaptive filter to be a predetermined value in response to detection of increase in a body motion change beyond a predetermined threshold value based on the body motion signal.

Abstract translation: 拍子检测装置包括：适于检测并输出脉波信号的脉波传感器; 身体运动传感器，其适于由于人体的身体运动而检测并输出人体运动信号; 脉波信号滤波部分，适于基于体动信号产生自适应滤波器以提取脉波信号中的噪声信号，并输出通过从脉波信号中消除噪声信号而获得的拍频信号; 以及滤波器系数设定部，其适于将所述自适应滤波器的系数响应于基于所述身体运动信号检测超过预定阈值的身体运动变化的增加而将所述自适应滤波器的系数设置为预定值。

公开(公告)号：US20070281394A1

公开(公告)日：2007-12-06

申请号：US11739798

申请日：2007-04-25

Applicant: Tadahiko Kawabe ,  Masao Kuroda ,  Yasuhiro Sugimoto ,  Hajime Saiki ,  Shinji Yuri ,  Makoto Origuchi

Inventor： Tadahiko Kawabe ,  Masao Kuroda ,  Yasuhiro Sugimoto ,  Hajime Saiki ,  Shinji Yuri ,  Makoto Origuchi

IPC: H01L21/02

CPC classification number: H05K1/185 ,  H01L21/4857 ,  H01L23/13 ,  H01L23/49822 ,  H01L23/50 ,  H01L2224/05568 ,  H01L2224/05573 ,  H01L2224/16 ,  H01L2224/16235 ,  H01L2924/00014 ,  H01L2924/01078 ,  H01L2924/09701 ,  H01L2924/15311 ,  H05K1/0231 ,  H05K1/112 ,  H05K3/4602 ,  H05K2201/10674 ,  H05K2201/10712 ,  Y10T29/49155 ,  H01L2224/05599

Abstract: A method for manufacturing a wiring board which can simplify a manufacturing step. In a preparation step, a core board and an electronic component are prepared. In an insulating layer formation and fixing step, after accommodating the electronic component in an accommodation hole, a lowermost resin insulating layer is formed, and a gap between the electronic component and the core board is filled with a part of the lowermost resin insulating layer so as to fix the electronic component to the core board. In an opening portion formation step, a portion of the lowermost resin insulating layer located directly above the gap between the electronic component and the core board is removed so as to form an opening portion exposing a part of a core board main surface side conductor and a component main surface side electrode. In a main surface side connecting conductor formation step, a main surface side connecting conductor is formed in the opening portion so as to connect the core board main surface side conductor to the component main surface side electrode.

Abstract translation: 一种制造布线板的方法，其可以简化制造步骤。 在准备步骤中，制备核心板和电子部件。 在绝缘层形成和定影步骤中，在将电子部件容纳在容纳孔中之后，形成最下层的树脂绝缘层，并且用最下层树脂绝缘层的一部分填充电子部件与芯板之间的间隙 以将电子部件固定到核心板。 在开口部形成工序中，除去位于电子部件与芯板之间的间隙正上方的最下层树脂绝缘层的一部分，以形成露出芯板主面侧导体和 部件主表面侧电极。 在主表面侧连接导体形成步骤中，在开口部分形成主表面侧连接导体，以将芯板主表面侧导体连接到部件主表面侧电极。

公开(公告)号：US20070263364A1

公开(公告)日：2007-11-15

申请号：US11739752

申请日：2007-04-25

Applicant: Tadahiko Kawabe ,  Masao Kuroda ,  Yasuhiro Sugimoto ,  Hajime Saiki ,  Shinji Yuri ,  Makoto Origuchi

Inventor： Tadahiko Kawabe ,  Masao Kuroda ,  Yasuhiro Sugimoto ,  Hajime Saiki ,  Shinji Yuri ,  Makoto Origuchi

IPC: H05K7/00

CPC classification number: H05K1/185 ,  H01L23/49822 ,  H01L23/50 ,  H01L23/642 ,  H01L2224/05568 ,  H01L2224/05573 ,  H01L2224/16235 ,  H01L2224/16237 ,  H01L2924/00014 ,  H01L2924/01078 ,  H01L2924/09701 ,  H01L2924/15311 ,  H05K1/0231 ,  H05K1/112 ,  H05K3/4602 ,  H05K2201/096 ,  H05K2201/10674 ,  H05K2201/10712 ,  H01L2224/05599

Abstract: A wiring board having an excellent electrical property and reliability or the like. The wiring board includes a core board, a capacitor and a resin filler. The core board includes an accommodation hole therein and a core board main surface side conductor disposed on the core main surface thereof. A capacitor main surface side electrode is disposed on a capacitor main surface of the capacitor. A gap between the capacitor accommodated in the accommodation hole and the core board is filled with the resin filler so that the capacitor is fixed to the core board. Further, the resin filler has a main surface side wiring forming portion on which a main surface side connecting conductor, which is connected to an end portion of a via conductor, is disposed so as to connect the core board main surface side conductor to the capacitor main surface side electrode.

Abstract translation: 具有优异的电性能和可靠性等的布线板。 布线板包括芯板，电容器和树脂填料。 芯板包括容纳孔和设置在其芯主表面上的芯板主表面侧导体。 电容器主面侧电极设置在电容器的电容器主表面上。 容纳在容纳孔中的电容器和芯板之间的间隙填充有树脂填料，使得电容器固定到芯板。 此外，树脂填料具有主表面侧布线形成部分，其上连接有通孔导体的端部的主表面侧连接导体，以将芯板主表面侧导体连接到电容器 主表面侧电极。

公开(公告)号：US06931348B2

公开(公告)日：2005-08-16

申请号：US10382279

申请日：2003-03-05

Applicant: Naoshi Furuta ,  Masao Kuroda

Inventor： Naoshi Furuta ,  Masao Kuroda

IPC: B63C11/02 ,  B63C11/32 ,  G04G99/00 ,  G01L11/00

CPC classification number: B63C11/32 ,  B63C2011/021

Abstract: Unnecessary operations are eliminated in the calculation of a non-decompression limit at the current water dept. In this manner, the calculation of the non-decompression limit is made more efficient and the required computing time is shorten to the point where the function can be incorporated into a wrist worn device that provides timely data.

Abstract translation: 在目前的水务部门计算非减压限值时，不必要的操作被消除。 以这种方式，使非减压极限的计算更有效，并且所需的计算时间缩短到可以将功能并入提供及时数据的腕部佩戴装置中的时间点。

公开(公告)号：US5443706A

公开(公告)日：1995-08-22

申请号：US266626

申请日：1994-06-28

Applicant: Masao Kuroda ,  Yutaka Sakakibara

Inventor： Masao Kuroda ,  Yutaka Sakakibara

IPC: C02F1/46 ,  C02F1/467 ,  C02F3/00 ,  C02F3/34 ,  C02F9/00 ,  C12Q1/00 ,  C02F1/461

CPC classification number: C02F3/302 ,  C02F3/005 ,  C02F3/34 ,  C12Q1/001 ,  C02F1/4676 ,  C02F2101/163 ,  C02F2101/22

Abstract: An electrode consists of a cathode matrix material and a biocatalyst immobilized on the matrix material. A water under treatment is treated by disposing the electrode as a cathode and an anode opposed thereto in the water, and applying an electric current between the cathode and the anode.

Abstract translation: 电极由阴极基体材料和固定在基质材料上的生物催化剂组成。 处理水是通过在水中设置作为阴极和与其相对的阳极的电极，并在阴极和阳极之间施加电流来处理的。

公开(公告)号：US5153124A

公开(公告)日：1992-10-06

申请号：US393001

申请日：1989-08-11

Applicant: Kouhei Furuya ,  Takao Okazaki ,  Yoshio Tsujita ,  Seigo Iwado ,  Kiyoshi Hamano ,  Masao Kuroda ,  Jun Yoshikawa ,  Toshiaki Iwai ,  Kunio Nakano

Inventor： Kouhei Furuya ,  Takao Okazaki ,  Yoshio Tsujita ,  Seigo Iwado ,  Kiyoshi Hamano ,  Masao Kuroda ,  Jun Yoshikawa ,  Toshiaki Iwai ,  Kunio Nakano

IPC: A61K31/225 ,  C07C67/31 ,  C07C69/675 ,  C07D309/10 ,  C07D309/30 ,  C12P7/62 ,  C12P17/06

CPC classification number: C12R1/645 ,  C07D309/10 ,  C12P17/06 ,  C12P7/62 ,  C12R1/365

Abstract: Derivatives of ML-236B carboxylic acid, its salts and esters and corresponding lactone have a hydroxy group at the 3"-position and optionally also at the 6'-position. These derivatives may be prepared by the enzymatic hydroxylation of a corresponding ML-236B compound employing an enzyme produced by a microorganism of the genus Streptomyces or Amycolata, especially Streptomyces sp. SANK 62285, Streptomyces sp. SANK 62385, Streptomyces sp. SANK 62485, Streptomyces sp. SANK 62585, Amycolata autotrophica SANK 62781, Amycolata autotrophica subsp. canberrica SANK 62882 or Amycolata autotrophica subsp. amethystina SANK 62981. These derivatives have the ability to inhibit cholesterol biosynthesis.

Abstract translation: ML-236B羧酸的衍生物，其盐和酯和相应的内酯在3“位和任选也在6'位具有羟基。 这些衍生物可以通过使用由链霉菌属或Amycolata属的微生物，特别是链霉菌属（Streptomyces sp。）产生的酶的相应的ML-236B化合物的酶促羟基化来制备。 SANK 62285，Streptomyces sp。 SANK 62385，Streptomyces sp。 SANK 62485，Streptomyces sp。 SANK 62585，Amycolata autotrophica SANK 62781，Amycolata autotrophica subsp。 canberrica SANK 62882或Amycolata autotrophica subsp。 紫杉醇SANK 62981.这些衍生物具有抑制胆固醇生物合成的能力。