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    POROUS MEMBRANES WITH A POLYMER GRAFTING, METHODS AND USES THEREOF
    11.
    发明申请
    POROUS MEMBRANES WITH A POLYMER GRAFTING, METHODS AND USES THEREOF 审中-公开
    多孔膜与聚合物接枝，其方法和用途

    公开(公告)号：US20160146795A1

    公开(公告)日：2016-05-26

    申请号：US14548338

    申请日：2014-11-20

    Applicant: General Electric Company

    Inventor： Bing Li ,  Brian Christopher Bales ,  David Roger Moore ,  Jason Michael Nichols ,  Cathryn Ellen Olsen ,  William Christopher Alberts ,  Frank John Mondello

    IPC: G01N33/548

    CPC classification number: G01N33/548 ,  B01D67/009 ,  B01D69/144 ,  B01D71/78 ,  G01N33/54353 ,  Y02A50/57

    Abstract: A modified porous membrane comprising a polymer coating grafted to a porous membrane is described. A method for analyte detection from a biological sample using an immunoassay is also provided using the modified membrane, wherein the method comprises a) providing a modified porous membrane having the structure of Formula (I), b) incubating the modified porous membrane with a first biomolecule, wherein the first biomolecule binds to the modified porous membrane to form a first biomolecule bound modified porous membrane; and c) adding a biological sample comprising at least an analyte to the first biomolecule bound modified porous membrane for analyte detection by binding the analyte to the first biomolecule bound to the modified porous membrane.

    Abstract translation: 描述了包含接枝到多孔膜上的聚合物涂层的改性多孔膜。 还提供了使用免疫测定法从生物样品中分析物检测的方法，其中所述方法包括：a）提供具有式（I）结构的改性多孔膜，b）将所述改性多孔膜与第一 生物分子，其中所述第一生物分子与修饰的多孔膜结合以形成第一生物分子结合的改性多孔膜; 和c）将包含至少一种分析物的生物样品添加到第一生物分子结合的改性多孔膜上，以通过将分析物结合到与修饰的多孔膜结合的第一生物分子来进行分析物检测。

    ELECTROSPUN FIBERS FOR PROTEIN STABLIZIATION AND STORAGE
    12.
    发明申请
    ELECTROSPUN FIBERS FOR PROTEIN STABLIZIATION AND STORAGE 审中-公开
    用于蛋白质稳定和储存的电纺纤维

    公开(公告)号：US20150176056A1

    公开(公告)日：2015-06-25

    申请号：US14140127

    申请日：2013-12-24

    Applicant: General Electric Company

    Inventor： Bing Li ,  David Roger Moore ,  William Christopher Alberts ,  John Richard Nelson

    IPC: C12Q1/68 ,  G01N33/543

    CPC classification number: C12Q1/6806 ,  G01N33/54346 ,  G01N33/54393

    Abstract: An electrospinning approach is disclosed for generating a dissolvable formulation of a reagent of interest in a nanoscale fiber medium. In one embodiment, the nanoscale fibers can incorporate and stabilize biological agents of interest, such as for storage at room temperature for extended periods. In one implementation, the fibers can be produced in a continuous manner and dissolve rapidly.

    Abstract translation: 公开了一种静电纺丝方法，用于在纳米级纤维介质中产生感兴趣的试剂的可溶性制剂。 在一个实施方案中，纳米级纤维可以掺入并稳定感兴趣的生物试剂，例如在室温下长时间储存​​。 在一个实施方案中，纤维可以以连续的方式生产并迅速溶解。

    Device for rapid diagnostic tests to detect antigens with improved sensitivity
    15.
    发明授权
    Device for rapid diagnostic tests to detect antigens with improved sensitivity 有权

    公开(公告)号：US10983119B2

    公开(公告)日：2021-04-20

    申请号：US15401333

    申请日：2017-01-09

    Applicant: General Electric Company ,  TOKITAE LLC

    Inventor： Bing Li ,  Matthew Jeremiah Misner ,  David Roger Moore ,  Kevin Paul Flood Nichols ,  David Cate ,  Matthew F Rosen

    IPC: G01N33/558 ,  G01N33/543

    Abstract: A rapid diagnostic testing device for testing of a biological sample is provided. The device comprises a channeled construct, at least one lateral flow unit, and a cassette housing. The channeled construct is configured to receive a biological sample to form at least partially purified biological sample. The lateral flow unit is at least partially disposed in the cassette housing. The lateral flow unit comprises: a sample receiving zone, a conjugate zone and a detection zone. The sample receiving zone is operatively coupled to the channeled construct for receiving the partially purified biological sample comprising at least one analyte. The conjugate zone comprising a conjugate particle to bind the analyte is disposed adjacent to the first side of the sample receiving zone. The detection zone is disposed adjacent to the second side of the sample receiving zone and comprises at least one binding agent for detecting the analyte.

    Water recovery system including integrated contactor with thermally-enhanced recovery
    18.
    发明授权
    Water recovery system including integrated contactor with thermally-enhanced recovery 有权

    公开(公告)号：US11739506B2

    公开(公告)日：2023-08-29

    申请号：US17168845

    申请日：2021-02-05

    Applicant: General Electric Company

    Inventor： David Roger Moore ,  Vitali Victor Lissianski ,  Albert Santo Stella ,  Daniel Jason Erno

    IPC: B01D53/04 ,  E03B3/28 ,  B01D53/26

    CPC classification number: E03B3/28 ,  B01D53/0407 ,  B01D53/0454 ,  B01D53/261 ,  B01D2257/80

    Abstract: A water recovery system including a first fluid stream inlet providing for the flow of a first fluid stream, such as a humidified inlet gas, into the system and a second fluid stream inlet providing for the flow of a second fluid stream, such as a gas having a temperature greater than the humidified inlet gas, into the system. At least one contactor is in fluid communication with the first fluid stream inlet and the second fluid stream inlet. The at least one contactor defining therein a first fluidically-isolated, sorbent-integrated, fluid domain for flow of the first fluid stream and water adsorption, a second fluidically-isolated fluid domain for flow of the second fluid stream wherein the second fluidically-isolated fluid domain is in thermal communication with the first fluidically-isolated, sorbent-integrated, fluid domain and a third fluidically-isolated fluid domain for capture of a condensate and recycling of latent heat of condensation back to the first fluidically-isolated, sorbent-integrated, fluid domain.

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