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    Method for producing silicone hydrogel contact lenses
    11.
    发明授权
    Method for producing silicone hydrogel contact lenses 有权

    公开(公告)号：US11254076B2

    公开(公告)日：2022-02-22

    申请号：US16429811

    申请日：2019-06-03

    Applicant: Alcon Inc.

    Inventor： Junhao Ge ,  Daqing Wu ,  Richard Charles Breitkopf ,  Steve Yun Zhang ,  Augustine Twum Kumi

    IPC: B29D11/00 ,  C08F226/10 ,  G02B1/04 ,  B29K83/00 ,  B29K105/00

    Abstract: The invention provides a contact lens manufacturing method comprising a process for removing unprocessed molded silicone hydrogel contact lenses from mold halves in a relatively efficient and consistent manner. A method of the invention comprising the steps of formulating a lens formulation by dissolving/blending all polymerizable components in a mixture a hydrophobic acrylic monomer as a reactive diluent and an organic solvent as a non-reactive diluent at a weight ratio of least 0.24 (reactive diluent over the sum of reactive and non-reactive solvents) per gram of the polymerizable composition and using a relatively low ultrasonic vibration energy for delensing. This method of the invention can be easily implemented in a production environment for enhancing the production yield.

    METHOD FOR PRODUCING EMBEDDED OR HYBRID HYDROGEL CONTACT LENSES
    12.
    发明申请
    METHOD FOR PRODUCING EMBEDDED OR HYBRID HYDROGEL CONTACT LENSES 有权

    公开(公告)号：US20210291469A1

    公开(公告)日：2021-09-23

    申请号：US17205148

    申请日：2021-03-18

    Applicant: Alcon Inc.

    Inventor： Yang Zheng ,  Junhao Ge ,  Steve Yun Zhang

    IPC: B29D11/00 ,  G02B1/04 ,  C08L83/04 ,  C08J3/075 ,  C08J3/24

    Abstract: The invention is generally related to a method for producing, in a relatively efficient and consistent manner, embedded or hybrid silicone hydrogel contact lenses, and also to unprocessed embedded or hybrid silicone hydrogel contact lenses, according to conventional cast-molding technologies. A method of the invention involve use of a polymeric non-reactive diluent in preparing a polymerizable composition for forming the silicone hydrogel material of the unprocessed embedded or hybrid silicone hydrogel contact lens, which is cast-molded with a lens mold. The unprocessed cast-molded embedded or hybrid silicone hydrogel contact lens has no or a minimal water-swelling degree, so that lens distortion or delamination during the hydration of the unprocessed embedded or hybrid silicone hydrogel contact lens.

    PHOTOCHROMIC POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS
    13.
    发明申请
    PHOTOCHROMIC POLYDIORGANOSILOXANE VINYLIC CROSSLINKERS 有权

    公开(公告)号：US20210284806A1

    公开(公告)日：2021-09-16

    申请号：US17199158

    申请日：2021-03-11

    Applicant: Alcon Inc.

    Inventor： Yuan Chang ,  Junhao Ge ,  Steve Yun Zhang ,  Weihong Lang

    IPC: C08G77/388 ,  C08L83/08

    Abstract: The invention provides a class of photochromic polydiorganosiloxane vinylic crosslinkers. Each of the photochromic polydiorganosiloxane vinylic crosslinkers of the invention comprise (1) a polydiorganosiloxane polymer chain comprising dimethylsiloxane units and photochromic siloxane unit having one methyl substituent and one organic substituent having a photochromic moiety that capable of undergoing a reversible color change upon exposure to UV-irradiation or high-energy-violet light; (2) two terminal ethylenically-unsaturated groups. The invention also provides a soft photochromic contact lens, especially a photochromic silicone hydrogel contact lens, which comprises a crosslinked polymeric material comprising repeating units of at least one of such a class of photochromic polydiorganosiloxane vinylic crosslinkers. The invention further provides a method of producing a photochromic contact lens from a polymerizable composition comprising at least one of such a class of photochromic polydiorganosiloxane vinylic crosslinkers.

    METHOD FOR DETERMINING COATING THICKNESS ON COATED CONTACT LENSES
    14.
    发明申请
    METHOD FOR DETERMINING COATING THICKNESS ON COATED CONTACT LENSES 有权

    公开(公告)号：US20210131923A1

    公开(公告)日：2021-05-06

    申请号：US17087983

    申请日：2020-11-03

    Applicant: Alcon Inc.

    Inventor： Yuan Chang ,  Ying Zheng ,  Junhao Ge ,  Steve Yun Zhang ,  Karen Belinda Sentell ,  Jinbo Dou

    IPC: G01N1/30 ,  G02B1/04 ,  G01N1/04 ,  G01N21/77

    Abstract: The invention provides a method for imaging and thickness determination of coatings on coated contact lenses. The method comprises selectively staining a negatively-charged-groups-containing coating over the lens body of a coated contact lens by immersing the coated contact lens in an aqueous solution comprising a fluorescently-labeled polycationic polymer and having a pH of from about 6.5 to 8.0; orthogonally cutting the selectively-stained coated contact lens; and determining the thickness of the coating on the coated contact lens. In addition, the invention provides a method for selecting a candidate coating material comprising negatively charged groups for applying a coating with a desired thickness onto silicone hydrogel contact lenses and for optimizing a coating process for producing coated silicone hydrogel contact lenses with a desired thickness coating thereon.

    Method for producing photochromic contact lenses
    19.
    发明授权
    Method for producing photochromic contact lenses 有权

    公开(公告)号：US11542353B2

    公开(公告)日：2023-01-03

    申请号：US16872628

    申请日：2020-05-12

    Applicant: Alcon Inc.

    Inventor： Weihong Lang ,  Junhao Ge ,  Steve Yun Zhang ,  Daqing Wu

    IPC: C08F271/02 ,  B29D11/00 ,  C08K5/1545 ,  C08K5/17 ,  B29K83/00 ,  B29K105/00 ,  G02B1/04

    Abstract: The invention provides a method for producing photochromic silicone hydrogel (SiHy) contact lenses based on thermal cast-molding technology in a relatively efficient and consistent manner. The method is characterized by selecting a high radical-reactive hydrophilic acrylic monomer while eliminating any low radical-reactive hydrophilic N-vinyl amide monomer in a lens formulation (polymerizable composition), by selecting a weight ratio of low-radical-reactive hydrophilic N-vinyl amide monomer to a high radical-reactive hydrophilic acrylic monomer in a lens formulation if the low radical-reactive hydrophilic N-vinyl amide monomer is needed, and/or by using a relatively high temperature thermal initiator in a lens formulation, to control the lens properties (e.g., water content, elastic modulus, etc.) and lens processability (capability of dry-delensing from molds) of thermally cast-molded SiHy contact lenses while minimizing loss in photochromic ability of resultant SiHy contact lenses.

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