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    Communication-Anchor Loop For Injectable Device
    11.
    发明申请
    Communication-Anchor Loop For Injectable Device 审中-公开
    通信锚点注入装置

    公开(公告)号：US20100191310A1

    公开(公告)日：2010-07-29

    申请号：US12509678

    申请日：2009-07-27

    申请人： Mark J. Bly

    发明人： Mark J. Bly

    IPC分类号： A61N1/08

    CPC分类号： A61B5/0031 ,  A61B5/6846 ,  A61B5/6882 ,  A61B17/3468 ,  A61B2560/063

    摘要： An injectable electronics device has a housing sized to fit within an injection tool lumen with one or more electrical components position within the housing, and a self-expanding loop antenna coupled to at least one electrical component within the housing. The self-expanding loop antenna is expandable from a first compressed shape to a second expanded shape.

    摘要翻译： 可注射电子设备具有壳体，其尺寸设置成在壳体内具有一个或多个电气部件位置的装配在注射工具内腔内，以及联接到壳体内的至少一个电气部件的自扩张环形天线。 自膨胀环形天线可从第一压缩形状扩展成第二扩展形状。

    Adherent Athletic Monitor
    13.
    发明申请
    Adherent Athletic Monitor 审中-公开
    贴身运动监护仪

    公开(公告)号：US20090076341A1

    公开(公告)日：2009-03-19

    申请号：US12209269

    申请日：2008-09-12

    申请人： Kristofer J. James ,  Badri Amurthur ,  Mark J. Bly ,  Imad Libbus

    发明人： Kristofer J. James ,  Badri Amurthur ,  Mark J. Bly ,  Imad Libbus

    IPC分类号： A61B5/02 ,  G08B23/00

    CPC分类号： A61B5/0002 ,  A61B5/02055 ,  A61B5/04085 ,  A61B5/6833 ,  A61B2560/0412 ,  A61B2562/164

    摘要： A system is provided for tracking an individual, engaged in extreme physical activity, physiological status and detecting and predicting negative physiological events. A monitoring system is provided that includes a plurality of sensors. Each sensor has a sensor output, and a combination of the sensor outputs is used to determine distress of the monitored individual engaged in extreme physical activity. A wireless communication device is coupled to the plurality of sensors and transfers data directly or indirectly from the plurality of sensors to a remote monitoring system. A remote monitoring system is coupled to the wireless communication device and configured to receive the processed data.

    摘要翻译： 提供一个跟踪个人的系统，从事极端的身体活动，生理状态，检测和预测负面的生理事件。 提供了包括多个传感器的监视系统。 每个传感器都有一个传感器输出，并且传感器输出的组合用于确定从事极端身体活动的受监视人员的困扰。 无线通信设备耦合到多个传感器并且将数据直接或间接地从多个传感器传送到远程监控系统。 远程监控系统耦合到无线通信设备并被配置为接收处理后的数据。

    DIRECT DELIVERY SYSTEM FOR TRANSVASCULAR LEAD
    14.
    发明申请
    DIRECT DELIVERY SYSTEM FOR TRANSVASCULAR LEAD 审中-公开
    直升机系统

    公开(公告)号：US20080183187A1

    公开(公告)日：2008-07-31

    申请号：US11669047

    申请日：2007-01-30

    申请人： Mark J. Bly

    发明人： Mark J. Bly

    IPC分类号： A61N1/05

    CPC分类号： A61N1/057 ,  A61N1/0558 ,  A61N1/36114

    摘要： A lead delivery system for delivering a neurostimulation lead to a patient's internal jugular vein using a percutaneous stick. The system comprises a neurostimulation lead adapted to stimulate a vagus nerve from the internal jugular vein. The lead includes a proximal end, a distal end, a generally spiral shaped retaining structure interposed between the proximal and distal ends and configured to retain the lead in the internal jugular vein, an electrode coupled to the retaining structure, and a side port interposed between the retaining structure and the proximal end. The side port provides access to a lumen extending from the distal end to the side port. A guidewire is sized to fit within the side port and lumen and reduce a force exerted by the retaining structure against the internal jugular vein, thereby allowing rotation of the lead and orientation of the electrode by applying a torque to the lead. A catheter has a lumen sized to slideably receive the medical electrical lead and configured to provide access to the internal jugular vein from the percutaneous stick site. A method of delivering a medical electrical lead to a patient's internal jugular vein.

    摘要翻译： 用于使用经皮棒递送神经刺激导致患者颈内静脉的引导递送系统。 该系统包括适于从颈内静脉刺激迷走神经的神经刺激引线。 引线包括近端，远端，插入在近端和远端之间的大致螺旋形的保持结构，并且构造成将引线保持在颈内静脉内，连接到保持结构的电极和插入在 保持结构和近端。 侧端口提供进入从远端延伸到侧端口的内腔。 导丝的尺寸设置成适合于侧端口和内腔，并且减小由保持结构抵抗颈内静脉施加的力，由此通过向引线施加扭矩来允许引线的引导和取向的旋转。 导管具有尺寸适于可滑动地接收医疗电引线并且被配置为提供从经皮粘连部位进入颈内静脉的内腔。 将医用电导线递送到患者的颈内静脉的方法。

    Retrograde pressure regulated infusion
    15.
    发明授权
    Retrograde pressure regulated infusion 有权
    逆行压力调节输液

    公开(公告)号：US07250041B2

    公开(公告)日：2007-07-31

    申请号：US10387048

    申请日：2003-03-12

    申请人： Jessica Chiu ,  Gregory Waimong Chan ,  Hongzhi Bai ,  Nianjiong J. Bei ,  Mark J. Bly ,  Srinivasan Sridharan ,  Tom Hatten

    发明人： Jessica Chiu ,  Gregory Waimong Chan ,  Hongzhi Bai ,  Nianjiong J. Bei ,  Mark J. Bly ,  Srinivasan Sridharan ,  Tom Hatten

    IPC分类号： A61M25/00

    CPC分类号： A61M25/10 ,  A61M25/1002 ,  A61M2025/1052

    摘要： A delivery catheter that includes a flexible shaft having a proximal end and a distal end, the distal end having an outer diameter less than about 13 mm; a delivery lumen having a proximal end and a distal end, the delivery lumen within the flexible shaft, the delivery lumen having at least an outlet port or at least one side hole at the distal end of the delivery lumen, the delivery lumen having a cross-sectional area at least about 5 mm2; a pressure monitoring lumen having a proximal end and a distal end, the pressure monitoring lumen within the flexible shaft; a pressure port adjacent to and connected to the distal end of the pressure monitoring lumen; a balloon inflation lumen having a proximal end and a distal end, the balloon inflation lumen within the flexible shaft; a soft tip at the distal end of the flexible shaft; a balloon at the distal end of the flexible shaft, the balloon connected to the distal end of the balloon inflation lumen, the balloon includes at least one of the following materials, polyether block amide resin, polyetheramide, polyurethane, silicone, natural latex, or synthetic latex; wherein the balloon is adapted to inflate to a diameter range of about 4 to about 15 mm.

    摘要翻译： 输送导管，其包括具有近端和远端的柔性轴，所述远端具有小于约13mm的外径; 输送腔，其具有近端和远端，所述输送腔在所述柔性轴内，所述输送腔至少具有出口端口或至少一个在所述输送腔的远端处的侧孔，所述输送腔具有交叉 至少约5毫米2的截面积; 具有近端和远端的压力监测管腔，所述柔性轴内的所述压力监测腔; 与所述压力监视管腔的远端相邻并连接的压力口; 具有近端和远端的球囊充气腔，所述气囊膨胀腔在所述柔性轴内; 在柔性轴的远端处的软尖端; 在柔性轴的远端处的气囊，气囊连接到球囊充气腔的远端，气囊包括以下材料中的至少一种：聚醚嵌段酰胺树脂，聚醚酰胺，聚氨酯，硅氧烷，天然胶乳或 合成胶乳 其中所述气囊适于膨胀至约4至约15mm的直径范围。

    Medical lead having a variable change in stiffness
    17.
    发明授权
    Medical lead having a variable change in stiffness 有权
    医疗铅具有可变的刚度变化

    公开(公告)号：US08554336B2

    公开(公告)日：2013-10-08

    申请号：US11277333

    申请日：2006-03-23

    申请人： Mark J. Bly ,  Brian D. Soltis ,  Bruce A. Tockman ,  Avram Scheiner

    发明人： Mark J. Bly ,  Brian D. Soltis ,  Bruce A. Tockman ,  Avram Scheiner

    IPC分类号： A61N1/00

    CPC分类号： A61N1/056 ,  A61N2001/0585

    摘要： According to one embodiment, the present invention includes an elongate implantable medical lead having a distal portion that is relatively flexible, a proximal portion that is relatively stiff, and a transition portion which has a variable transition stiffness. The transition stiffness varies over the length of the transition portion that generally decreases in a distal direction. The relatively stiff proximal portion of the lead gives the lead steerability while the gradual change in stiffness in the transition portion reduces the likelihood that the lead will prolapse when it is guided into a branch vein. The distal stiffness is less than the proximal stiffness giving the lead a safe end that is unlikely to puncture vascular walls and is able to maneuver around various tortuosities when the lead is implanted into a patient.

    摘要翻译： 根据一个实施例，本发明包括细长的可植入医疗引线，其具有相对柔性的远侧部分，相对刚性的近端部分和具有可变过渡刚度的过渡部分。 过渡刚度在远端方向上通常减小的过渡部分的长度上变化。 引线的相对刚性的近端部分具有引导操纵性，而过渡部分中刚度的逐渐变化降低了当引导到分支静脉时引线脱垂的可能性。 远端刚度小于近端刚度，使得引线成为不可能穿透血管壁的安全端，并且当铅被植入患者时能够围绕各种曲折进行操纵。

    Direct delivery system for transvascular lead
    18.
    发明授权
    Direct delivery system for transvascular lead 有权
    直接输血系统用于经血管引流

    公开(公告)号：US08311647B2

    公开(公告)日：2012-11-13

    申请号：US13079512

    申请日：2011-04-04

    申请人： Mark J. Bly

    发明人： Mark J. Bly

    IPC分类号： A61N1/00

    CPC分类号： A61N1/057 ,  A61N1/0558 ,  A61N1/36114

    摘要： A lead delivery system for delivering a neurostimulation lead to a patient's internal jugular vein using a percutaneous stick. The system comprises a neurostimulation lead adapted to stimulate a vagus nerve from the internal jugular vein. The lead includes a proximal end, a distal end, a generally spiral shaped retaining structure interposed between the proximal and distal ends and configured to retain the lead in the internal jugular vein, an electrode coupled to the retaining structure, and a side port interposed between the retaining structure and the proximal end. The side port provides access to a lumen extending from the distal end to the side port. A guidewire is sized to fit within the side port and lumen and reduce a force exerted by the retaining structure against the internal jugular vein, thereby allowing rotation of the lead and orientation of the electrode by applying a torque to the lead. A catheter has a lumen sized to slideably receive the medical electrical lead and configured to provide access to the internal jugular vein from the percutaneous stick site. A method of delivering a medical electrical lead to a patient's internal jugular vein.

    摘要翻译： 用于使用经皮棒递送神经刺激导致患者颈内静脉的引导递送系统。 该系统包括适于从颈内静脉刺激迷走神经的神经刺激引线。 引线包括近端，远端，插入在近端和远端之间的大致螺旋形的保持结构，并且构造成将引线保持在颈内静脉内，连接到保持结构的电极和插入在 保持结构和近端。 侧端口提供进入从远端延伸到侧端口的内腔。 导丝的尺寸设置成适合于侧端口和内腔，并且减小由保持结构抵抗颈内静脉施加的力，由此通过向引线施加扭矩来允许引线的引导和取向的旋转。 导管具有尺寸适于可滑动地接收医疗电引线并且被配置为提供从经皮粘连部位进入颈内静脉的内腔。 将医用电导线递送到患者的颈内静脉的方法。

    Adherent device for sleep disordered breathing
    20.
    发明授权
    Adherent device for sleep disordered breathing 有权
    睡眠呼吸障碍的粘附装置

    公开(公告)号：US08249686B2

    公开(公告)日：2012-08-21

    申请号：US12209292

    申请日：2008-09-12

    申请人： Imad Libbus ,  Yatheendhar D. Manicka ,  Mark J. Bly

    发明人： Imad Libbus ,  Yatheendhar D. Manicka ,  Mark J. Bly

    IPC分类号： A61B5/04

    CPC分类号： A61B5/4818 ,  A61B5/0002 ,  A61B5/0205 ,  A61B5/02055 ,  A61B5/04085 ,  A61B5/0809 ,  A61B5/11 ,  A61B5/14551 ,  A61B5/6832 ,  A61B5/6833 ,  A61B5/7282 ,  A61B2560/0412 ,  A61B2562/164

    摘要： An adherent device is configured to adhere to the skin of the patient with an adherent patch, for example breathable tape, coupled to at least four electrodes. The device comprises impedance circuitry coupled to the at least four electrodes and configured to measure respiration of the patient to detect sleep apnea and/or hypopnea. The impedance circuitry may be used to measure hydration of the patient. An accelerometer can be mechanically coupled to the adherent patch such that the accelerometer can be coupled to and move with the skin of the patient. Electrocardiogram circuitry to generate an electrocardiogram signal may be coupled to at least two of the at least four electrodes to detect the sleep apnea and/or hypopnea.

    摘要翻译： 贴附装置被配置为使用与至少四个电极耦合的粘附贴片（例如透气带）粘附到患者的皮肤。 该装置包括耦合到至少四个电极并被配置为测量患者的呼吸以检测睡眠呼吸暂停和/或呼吸不足的阻抗电路。 阻抗电路可以用于测量患者的水合。 加速度计可以机械耦合到粘附贴片，使得加速度计可以耦合到患者皮肤并与患者的皮肤一起移动。 用于产生心电图信号的心电图电路可以耦合到至少四个电极中的至少两个，以检测睡眠呼吸暂停和/或呼吸不足。