公开(公告)号：US08173154B2

公开(公告)日：2012-05-08

申请号：US12683244

申请日：2010-01-06

申请人： Steven B. Jung ,  Delbert E. Day

发明人： Steven B. Jung ,  Delbert E. Day

IPC分类号： A61L15/00 ,  A61K33/22 ,  A61K33/34 ,  A61K33/00 ,  A61K33/14 ,  A61K33/32 ,  A61K33/38 ,  A61K33/26 ,  A61K33/42 ,  A61F13/00

CPC分类号： A61L15/18 ,  A61F13/00008 ,  A61F13/00034 ,  A61F13/069 ,  A61F2013/00157 ,  A61F2013/00221 ,  A61F2013/00519 ,  A61F2013/00829 ,  A61F2013/00936 ,  A61K9/0014 ,  A61K9/06 ,  A61K33/16 ,  A61K33/22 ,  A61K33/26 ,  A61K33/30 ,  A61K33/32 ,  A61K33/34 ,  A61K33/38 ,  A61L15/42 ,  A61L15/425 ,  A61L15/44 ,  A61L15/64 ,  A61L17/00 ,  A61L26/0004 ,  A61L26/0009 ,  A61L26/0085 ,  A61L2300/10 ,  A61L2300/102 ,  A61L2300/112 ,  A61L2300/412 ,  A61L2400/12

摘要： A method and compositions for wound care management comprising a dressing comprising a three-dimensional body of glass-based fibers comprising 40 to 80 weight % B2O3, wherein at least 25 wt. % of the fibers have a diameter between 200 nm and 4000 nm, and a length:width aspect ratio of at least 10. The glasses may also be used for wound care as fibers formed into sutures, as particles in surgical glue to close a wound, or as particles in an ointment or cream to apply to a wound. The compositions may comprise glass formers P2O5 and/or SiO2; alkali oxides selected from Li2O, Na2O, K2O, and Rb2O; and/or alkaline earth oxides selected from MgO, SrO, BaO and CaO. The compositions may further comprise 0.05 to 10 wt. % of one or more trace elements selected from Ag, Cu, F, Fe, Mn, Mo, Ni, Sr, and Zn.

摘要翻译： 一种用于伤口护理管理的方法和组合物，包括一种敷料，其包括含有40至80重量％B 2 O 3的玻璃基纤维的三维体，其中至少25重量％ 纤维的百分比具有在200nm和4000nm之间的直径，并且长度：宽度纵横比至少为10.该玻璃也可用于作为缝合线形成的纤维的伤口护理，作为手术胶中的颗粒以闭合伤口 ，或作为软膏或霜剂中的颗粒施用于伤口。 组合物可以包含玻璃形成剂P2O5和/或SiO 2; 选自Li2O，Na2O，K2O和Rb2O的碱金属氧化物; 和/或选自MgO，SrO，BaO和CaO的碱土氧化物。 组合物还可包含0.05至10wt。 选自Ag，Cu，F，Fe，Mn，Mo，Ni，Sr和Zn中的一种或多种微量元素的％。

公开(公告)号：US20080138602A1

公开(公告)日：2008-06-12

申请号：US11907337

申请日：2007-10-11

申请人： Leigh Canham ,  Roger Aston

发明人： Leigh Canham ,  Roger Aston

IPC分类号： B32B3/26 ,  D02G3/00 ,  A61F2/02 ,  A61F13/15 ,  A61F2/06 ,  A61F2/04 ,  A61B5/0408 ,  A61N1/04

CPC分类号： A61F13/44 ,  A61B17/06166 ,  A61F2/90 ,  A61F13/00017 ,  A61F13/00051 ,  A61F13/00063 ,  A61F13/00995 ,  A61F2013/00187 ,  A61F2013/00429 ,  A61F2013/00442 ,  A61F2013/00646 ,  A61F2013/00906 ,  A61L15/08 ,  A61L17/00 ,  A61L27/047 ,  D01F1/10 ,  D01F9/08 ,  D02G3/448 ,  D10B2401/16 ,  Y10T428/249962 ,  Y10T428/2915 ,  Y10T428/2927 ,  Y10T428/2929 ,  Y10T442/3065 ,  Y10T442/3089 ,  Y10T442/3146 ,  Y10T442/3976 ,  Y10T442/425 ,  Y10T442/608 ,  Y10T442/609 ,  Y10T442/613 ,  Y10T442/614 ,  Y10T442/637 ,  Y10T442/696 ,  Y10T442/697

摘要： A fibre or fabric comprising silicon for use as a medical fibre or fabric. The silicon present can be biocompatible, bioactive or resorbable material and may also be able to act as an electrical conductor. In addition, porous silicon may be used as a slow release means for example for drugs or fragrances, or as a collector for example for sweat. Novel fibres, fabrics and methods of preparation of these are also described and claimed.

摘要翻译： 包含用作医用纤维或织物的硅的纤维或织物。 存在的硅可以是生物相容的，生物活性的或可再吸收的材料，并且还可以作为电导体。 此外，多孔硅可以用作缓释装置，例如用于药物或香料，或作为例如汗液的收集器。 还描述和要求保护新颖的纤维，织物及其制备方法。

公开(公告)号：US20070239207A1

公开(公告)日：2007-10-11

申请号：US11632316

申请日：2005-02-15

申请人： Jose Beramendi

发明人： Jose Beramendi

IPC分类号： A61L17/00

CPC分类号： A61B17/06166 ,  A61B2017/00792 ,  A61B2017/06176 ,  A61B2017/0619 ,  A61L17/00

摘要： The present invention refers to surgery threads which are flexible, made of resistant inert plastic material and being employed in aesthetic surgeries in the cases of skin ageing prevention and/or correction surgeries for motion injury signals, wherein the threads comprise a previous defined sequence of a tissue support arrangement having a number of fixing claws placed alongside of the thread surface and wherein an arrangement of an upstream claw (1) set and a downstream claw (2) set is provided.

摘要翻译： 本发明涉及一种手术线，其是柔性的，由耐性惰性塑料材料制成，并且在用于运动损伤信号的皮肤老化预防和/或矫正手术的情况下用于美容手术中，其中线程包括先前定义的 组织支撑装置具有沿着螺纹表面放置的多个固定爪，并且其中设置有上游爪（1）和下游爪（2）的组合。

公开(公告)号：US06358271B1

公开(公告)日：2002-03-19

申请号：US09486760

申请日：2000-12-08

申请人： Thomas D. Egan ,  Paul V. Fenton, Jr.

发明人： Thomas D. Egan ,  Paul V. Fenton, Jr.

IPC分类号： A61B1700

CPC分类号： B29C65/08 ,  A61B17/0487 ,  A61B17/06166 ,  A61B17/320068 ,  A61B2017/00526 ,  A61B2017/0454 ,  A61B2017/0619 ,  A61L17/00 ,  B29C66/1122 ,  B29C66/5261 ,  B29C66/69 ,  B29C66/71 ,  B29C66/73921 ,  B29C66/80 ,  B29C66/81422 ,  B29C66/81423 ,  B29C66/81433 ,  B29C66/81463 ,  B29C66/8322 ,  B29K2023/12 ,  B29K2067/043 ,  B29K2077/00 ,  B29K2101/12 ,  B29L2031/709 ,  B29L2031/7096 ,  B29L2031/7102 ,  B29C65/00 ,  B29K2067/00

摘要： This invention is a fused loop (10) of an elongated material such as a surgical suture, and apparatus for making the loop. Portions of one or more segments (12) to be joined together are fused in a welding process to form a welded joint (14). The shear area of the fused portion (20) of the joint (14) determines the strength of the joint (14), and is thus preferably relatively large. Various configurations for the welding apparatus facilitate the creation of relatively large fused portions (20) of the joint (14) by maximizing contact between at least one of the welding members of the apparatus, and at least one of the segments (12) to be joined.

摘要翻译： 本发明是诸如外科缝合线的细长材料的熔合环（10）和用于制造环的装置。 要焊接在一起的一个或多个部分（12）的部分在焊接过程中熔合以形成焊接接头（14）。 接头（14）的熔融部分（20）的剪切面积确定接头（14）的强度，因此优选地相对较大。 用于焊接设备的各种配置通过使设备的至少一个焊接构件和至少一个段（12）之间的接触最大化来促进接头（14）的相对较大的熔融部分（20）的形成 加入。

公开(公告)号：US5514581A

公开(公告)日：1996-05-07

申请号：US609716

申请日：1990-11-06

申请人： Franco A. Ferrari ,  Joseph Cappello

发明人： Franco A. Ferrari ,  Joseph Cappello

IPC分类号： A61L17/00 ,  A61L29/04 ,  C07K14/00 ,  C07K14/435 ,  C07K14/78 ,  C07K17/08 ,  C12N1/06 ,  C12N5/00 ,  C12N15/11 ,  C12N15/62 ,  C12N15/66 ,  C12N15/70 ,  C12N15/75 ,  G03C1/047 ,  C12N1/21 ,  C12N15/12

CPC分类号： A61L17/00 ,  A61L29/049 ,  C07K14/00 ,  C07K14/43586 ,  C07K14/78 ,  C07K17/08 ,  C12N1/06 ,  C12N15/11 ,  C12N15/62 ,  C12N15/66 ,  C12N15/70 ,  C12N15/75 ,  C12N5/0068 ,  C07K2319/00 ,  C07K2319/02 ,  C07K2319/33 ,  C07K2319/61 ,  C12N2533/30 ,  C12N2533/52 ,  G03C1/047

摘要： Novel polymers are provided which are produced by recombinant techniques. The polymers are characterized by having a small repeating sequence which provides for strands capable of associating, resulting in useful structural characteristics, where the strands are joined by turns or loops which are flexible and available for interaction with the environment. Specifically, repeating groups of naturally occurring proteins such as silk are modified by introduction of an amino-acid sequence at a site which provides for a turn between strands to provide for readily available oligopeptides capable of interacting with molecules in the environment.

公开(公告)号：US5226336A

公开(公告)日：1993-07-13

申请号：US780560

申请日：1991-10-17

申请人： Peter A. Coates

发明人： Peter A. Coates

IPC分类号： A61B17/06 ,  A61L17/00 ,  D02J1/22

CPC分类号： A61L17/00 ,  A61B17/06166 ,  D02J1/22 ,  Y10S83/909 ,  Y10T83/283 ,  Y10T83/323 ,  Y10T83/8782

摘要： An apparatus for cutting at least one end of a surgical suture is described. The apparatus comprises a first pair of feed rollers which advance the surgical suture through a hole (or opening) in a cutting assembly. The first pair of feed rollers is driven by a stepper motor. A second pair of friction rollers take up the slack (i.e., provide tension) to the surgical suture beyond the cutting assembly. The second pair of friction rollers is driven by an electric or stepper motor. The cutting assembly comprises an anvil plate in which the hole is positioned, and a razor blade which is placed in a movable bracket against the anvil plate. The cutting edge of the razor blade is driven by a spring across the hole and cuts the surgical suture. The spring is activated (and can be reactivated for repetitive steps) by an electric motor.

摘要翻译： 描述了用于切割外科缝合线的至少一端的装置。 该装置包括第一对进给辊，其使外科缝合线通过切割组件中的孔（或开口）。 第一对进给辊由步进电机驱动。 第二对摩擦辊承受超过切割组件的外科缝合线的松弛（即，提供张力）。 第二对摩擦辊由电动或步进电机驱动。 所述切割组件包括其中定位所述孔的砧座板，以及将剃刀刀片放置在抵靠所述砧板的可移动支架中。 剃刀刀片的切割边缘由穿过孔的弹簧驱动并切割外科缝合线。 弹簧被电动机激活（并可重新激活重复步骤）。

公开(公告)号：US4589882A

公开(公告)日：1986-05-20

申请号：US533524

申请日：1983-09-19

申请人： Dan W. Urry

发明人： Dan W. Urry

IPC分类号： A61L17/00 ,  A61L27/22 ,  A61L27/40 ,  C08G69/10 ,  D01F8/00 ,  A61F2/02 ,  A61F2/06 ,  A61K37/00

CPC分类号： D01F8/00 ,  A61L17/00 ,  A61L27/227 ,  A61L27/40 ,  C08G69/10 ,  Y10S930/31

摘要： A method of repairing a natural elastic system in a human or animal body, which comprises replacing a damaged portion of the system with a shaped artificial elastomeric copolymer comprising an elastomeric component selected from the group consisting of tetrapeptide and pentapeptide repeating units or mixtures thereof wherein the repeating units comprise amino acid residues selected from the group consisting of hydrophobic amino acid and glycine residues and the repeating units exist in a conformation having a .beta.-turn and a crosslinking component selected from the group consisting of amino acid and peptide residues of the formula ##STR1## wherein .alpha. represents a covalent bond or a peptide fragment containing 1-10 .alpha.-helix-forming amino acid residues, B represents a covalent bond or a petide fragment containing 1-10 amino acid residues, and n is an integer from 2 to 6; wherein the copolymer optionally comprises a chemotactic component selected from the group consisting of -Ala-Pro-Gly-Val-Gly-Val-, -Pro-Gly-Val-Gly-Val-Ala-, -Gly-Val-Gly-Val-Ala-Pro-, -Val-Gly-Val-Ala-Pro-Gly-, -Gly-Val-Ala-Pro-Gly-Val-, and -Val-Ala-Pro-Gly-Val-Gly- and is essentially devoid of peptide fragments which occur in natural elastin other than these elastomeric, crosslinking, and chemotactic components, is disclosed along with elastomeric copolymers suitable for use in the method of the invention and methods of synthesizing such bioelastomers.

摘要翻译： 一种修复人或动物体内的天然弹性体系的方法，其包括用成形的人造弹性体共聚物代替系统的损坏部分，所述成形人造弹性体共聚物包含选自四肽和五肽重复单元或其混合物的弹性组分，其中 重复单元包括选自疏水性氨基酸和甘氨酸残基的氨基酸残基，并且重复单元以具有β转角和交联成分的构型存在，所述结构选自下列化学式的氨基酸和肽残基： IMAGE>其中α表示共价键或含有1-10个α-螺旋形成氨基酸残基的肽片段，B表示共价键或含有1-10个氨基酸残基的petide片段，n为2- 6; 其中所述共聚物任选地包含选自以下的趋化成分：-Ala-Pro-Gly-Val-Gly-Val-，-Pro-Gly-Val-Gly-Val-Ala-，-Gly-Val-Gly-Val -Ala-Pro-，-Val-Gly-Val-Ala-Pro-Gly-，-Gly-Val-Ala-Pro-Gly-Val-和-Val-Ala-Pro-Gly-Val-Gly- 基本上没有发生在除了这些弹性体，交联和趋化性组分之外的天然弹性蛋白中发生的肽片段以及适用于本发明方法的弹性体共聚物和合成这种生物弹性体的方法。