Halogen-containing organosulfur compound and use thereof
    97.
    发明授权
    Halogen-containing organosulfur compound and use thereof 有权
    含卤素的有机硫化合物及其用途

    公开(公告)号:US08247596B2

    公开(公告)日:2012-08-21

    申请号:US12665670

    申请日:2008-06-26

    摘要: There is provided a halogen-containing organosulfur compound having an excellent controlling effect on arthropod pests represented by the formula (I): wherein, m represents 0, 1 or 2, n represents 0, 1 or 2, A represents optionally substituted C3-C7 cycloalkyl or optionally substituted C5-C7 cycloalkenyl group, Q represents a C1-C5 haloalkyl group containing at least one fluorine atom, or a fluorine atom, R1 and R3 independently represent optionally substituted C1-C4 chain hydrocarbon, halogen or hydrogen, R2 and R4 independently represent optionally substituted C1-C4 chain hydrocarbon, —C(═G)R5, cyano, halogen or hydrogen, G represents oxygen or sulfur, and R5 represents optionally substituted C1-C4 alkyl, hydroxyl, optionally substituted C1-C4 alkoxy, optionally substituted C3-C6 alkenyloxy, optionally substituted C3-C6 alkynyloxy, amino, optionally substituted C1-C4 alkylamino, optionally substituted di(C1-C4 alkyl)amino, C2-C5 cyclic amino or hydrogen.

    摘要翻译: 提供对由式(I)表示的节肢动物害虫具有优异控制作用的含卤素的有机硫化合物:其中m表示0,1或2,n表示0,1或2,A表示任选取代的C 3 -C 7 环烷基或任选取代的C 5 -C 7环烯基,Q表示含有至少一个氟原子的C 1 -C 5卤代烷基或氟原子,R 1和R 3独立地表示任选取代的C 1 -C 4链烃,卤素或氢,R 2和R 4 独立地表示任选取代的C 1 -C 4链烃,-C(= G)R 5,氰基,卤素或氢,G表示氧或硫,R 5表示任选取代的C 1 -C 4烷基,羟基,任选取代的C 1 -C 4烷氧基, 取代的C 3 -C 6烯氧基,任选取代的C 3 -C 6炔氧基,氨基,任选取代的C 1 -C 4烷基氨基,任选取代的二(C 1 -C 4烷基)氨基,C 2 -C 5环氨基或氢。

    Thio-substituted arylmethanesulfinyl derivatives
    98.
    发明授权
    Thio-substituted arylmethanesulfinyl derivatives 有权
    硫代取代的芳基甲亚磺酰基衍生物

    公开(公告)号:US08071604B2

    公开(公告)日:2011-12-06

    申请号:US11983237

    申请日:2007-11-08

    摘要: The present invention is related to chemical compositions, processes for the preparation thereof and uses of the composition. Particularly, the present invention relates to compositions of compounds of Formula (A): wherein Ar, X, Y, R1, R2, R3, and q are as defined herein; and their use in the treatment of diseases, including treatment of sleepiness, promotion of wakefulness, treatment of Parkinson's disease, cerebral ischemia, stroke, sleep apneas, eating disorders, stimulation of appetite and weight gain, treatment of attention deficit hyperactivity disorder (“ADHD”), enhancing function in disorders associated with hypofunctionality of the cerebral cortex, including, but not limited to, depression, schizophrenia, fatigue, in particular, fatigue associated with neurologic disease, such as multiple sclerosis, chronic fatigue syndrome, and improvement of cognitive dysfunction.

    摘要翻译: 本发明涉及化学组成,其制备方法和组合物的用途。 特别地,本发明涉及式(A)化合物的组合物:其中Ar,X,Y,R 1,R 2,R 3和q如本文所定义; 以及它们在治疗疾病中的用途,包括治疗嗜睡,促进觉醒,治疗帕金森病,脑缺血,中风,睡眠呼吸暂停,进食障碍,刺激食欲和体重增加,治疗注意力缺陷多动障碍(“ADHD “),增强与大脑皮层功能低下相关疾病的功能,包括但不限于抑郁症,精神分裂症,疲劳,特别是与神经系统疾病如多发性硬化,慢性疲劳综合征和认知功能改善有关的疲劳 功能障碍。

    SULFONE COMPOUND AND PROCESS FOR PRODUCING CAROTENOID USING THE SAME COMPOUND
    100.
    发明申请
    SULFONE COMPOUND AND PROCESS FOR PRODUCING CAROTENOID USING THE SAME COMPOUND 审中-公开
    SULFONE化合物和使用该化合物生产卡波溶液的方法

    公开(公告)号:US20110015441A1

    公开(公告)日:2011-01-20

    申请号:US12920953

    申请日:2009-03-03

    摘要: The present invention relates to a process for producing a sulfone compound of the following formula (3), characterized in that an allyl sulfone compound of the formula (1) and an allyl halide compound of the formula (2) are reacted in an organic solvent in the presence of an alkali metal hydroxide and a phase-transfer catalyst: wherein A is CH2 or C═O; Ar is an aryl group optionally having 1 to 3 substitutents; and the wavy line means that the steric relation to the double bond which the wavy line is bound to is of E-form, Z-form or a mixture of E/Z; wherein X is a halogen atom; and the wavy line means the same as defined above; and wherein A, Ar and the wavy line mean the same as defined above. The present invention also relates to a process for producing a carotenoid from the same sulfone compound.

    摘要翻译: 本发明涉及下述式(3)的砜化合物的制造方法,其特征在于,将式(1)的烯丙基砜化合物和式(2)的烯丙基卤化合物在有机溶剂 在碱金属氢氧化物和相转移催化剂存在下,其中A是CH 2或C = O; Ar是任选具有1至3个取代基的芳基; 波浪线意味着与波浪线所绑定的双键的立体关系为E型,Z型或E / Z的混合物; 其中X是卤素原子; 波浪线与上述相同; 并且其中A,Ar和波浪线表示与上述相同的含义。 本发明还涉及由相同的砜化合物生产类胡萝卜素的方法。