-
公开(公告)号:US20240336567A1
公开(公告)日:2024-10-10
申请号:US18272577
申请日:2022-01-23
申请人: AG Plenus Ltd
IPC分类号: C07D213/79 , A01N37/30 , A01N37/40 , A01N43/08 , A01N43/10 , A01N43/36 , A01N43/40 , A01N43/54 , A01N43/56 , A01N43/653 , A01N43/76 , A01N43/78 , A01N43/80 , A01N43/82 , A01P13/00 , C07C217/56 , C07C233/83 , C07D207/36 , C07D207/38 , C07D231/20 , C07D239/34 , C07D249/12 , C07D261/18 , C07D263/38 , C07D271/113 , C07D277/56 , C07D307/68 , C07D333/40
CPC分类号: C07D213/79 , A01N37/30 , A01N37/40 , A01N43/08 , A01N43/10 , A01N43/36 , A01N43/40 , A01N43/54 , A01N43/56 , A01N43/653 , A01N43/76 , A01N43/78 , A01N43/80 , A01N43/82 , A01P13/00 , C07C217/56 , C07C233/83 , C07D207/36 , C07D207/38 , C07D231/20 , C07D239/34 , C07D249/12 , C07D261/18 , C07D263/38 , C07D271/113 , C07D277/56 , C07D307/68 , C07D333/40
摘要: The present invention relates to novel pesticidally and/or herbicidally active compounds, agrochemical composition thereof, methods of preparation thereof, and uses thereof for controlling the growth of undesirable plants (e.g., weeds), for example in crop fields.
-
公开(公告)号:US12091602B2
公开(公告)日:2024-09-17
申请号:US17504307
申请日:2021-10-18
发明人: Brent Shanks , George A. Kraus , William Bradley , Jiajie Huo , Kyle Podolak
IPC分类号: C09K15/30 , C07D213/70 , C07D233/84 , C07D235/28 , C07D249/12 , C07D277/36 , C07D285/125 , C07D405/12 , C07D409/12 , C07D417/12 , C09D5/08
CPC分类号: C09K15/30 , C07D213/70 , C07D233/84 , C07D235/28 , C07D249/12 , C07D277/36 , C07D285/125 , C07D405/12 , C07D409/12 , C07D417/12 , C09D5/086
摘要: A heteroaryl-thio-substituted pyrone compound that is a heteroaryl-thio-substituted pyrone or a heteroaryl-thio-substituted coumarin. In various embodiments, the heteroaryl-thio-substituted pyrone compound or a reaction product thereof is a metal corrosion inhibitor.
-
公开(公告)号:US12065411B1
公开(公告)日:2024-08-20
申请号:US18428286
申请日:2024-01-31
发明人: Mai Mostafa Khalaf Ali , Hany Mohamed Abd El-Lateef Ahmed , Antar Ahmed Abdelhamid Ahmed , Amer A. Amer
IPC分类号: C07D249/12 , A61P31/04 , A61P31/10
CPC分类号: C07D249/12 , A61P31/04 , A61P31/10
摘要: An methyl 4-((5-(3-fluorophenyl)-4-phenyl-4H-1,2,4-triazol-3-ylthio)methyl)benzoate compound, its synthesis, and its use as an antimicrobial agent.
-
公开(公告)号:US12054464B1
公开(公告)日:2024-08-06
申请号:US18428327
申请日:2024-01-31
发明人: Mai Mostafa Khalaf Ali , Hany Mohamed Abd El-Lateef Ahmed , Antar Ahmed Abdelhamid Ahmed , Amer A. Amer
IPC分类号: C07D249/12 , A61P31/04 , A61P31/10
CPC分类号: C07D249/12 , A61P31/04 , A61P31/10
摘要: An methyl 4-((5-(3-fluorophenyl)-4-phenyl-4H-1,2,4-triazol-3-ylthio)methyl)benzoate compound, its synthesis, and its use as an antimicrobial agent.
-
公开(公告)号:US20240254078A1
公开(公告)日:2024-08-01
申请号:US18606722
申请日:2024-03-15
发明人: Hongguang XIA , Mengyang FAN , Xufeng CEN , Xiaoyan XU , Ronghai WU , Dong LIU , Zhen TIAN
IPC分类号: C07C311/21 , A61K31/18 , A61K31/337 , A61K31/381 , A61K31/402 , A61K31/41 , A61K31/415 , A61K31/4192 , A61K31/4196 , A61K31/42 , A61K31/433 , A61K31/44 , C07D207/06 , C07D231/18 , C07D249/04 , C07D249/12 , C07D257/04 , C07D261/10 , C07D285/06 , C07D305/08 , C07D333/34 , C07D333/62
CPC分类号: C07C311/21 , A61K31/18 , A61K31/337 , A61K31/381 , A61K31/402 , A61K31/41 , A61K31/415 , A61K31/4192 , A61K31/4196 , A61K31/42 , A61K31/433 , A61K31/44 , C07D207/06 , C07D231/18 , C07D249/04 , C07D249/12 , C07D257/04 , C07D261/10 , C07D285/06 , C07D305/08 , C07D333/34 , C07D333/62
摘要: The present application discloses small molecule compounds having a naphthylamine structure and an application thereof. In the present application, the structure of a compound having a structure as shown in general formula (I) is as shown in the drawing. The compound and the pharmaceutically acceptable salt, stereoisomer, solvate or prodrug thereof that are provided by the present application or the pharmaceutical composition provided by the present application can selectively induce autophagy in damaged mitochondria without affecting or only weakly affecting normal mitochondria, and further have superior metabolic stability and pharmacokinetic properties, lower toxicity, and better druggability.
-
公开(公告)号:US11970466B1
公开(公告)日:2024-04-30
申请号:US18383754
申请日:2023-10-25
发明人: Hany Mohamed Abd El-Lateef Ahmed , Mai Mostafa Khalaf Ali , Antar Ahmed Abdelhamid Ahmed , Amer A. Amer
IPC分类号: C07D249/12 , A61P31/04 , A61P31/10
CPC分类号: C07D249/12 , A61P31/04 , A61P31/10
摘要: A 4-((5-(3-fluorophenyl)-4-phenyl-4H-1,2,4-triazol-3-ylthio)methyl)benzoic acid compound, its synthesis, and its use as an antimicrobial agent.
-
7.
公开(公告)号:US11970465B1
公开(公告)日:2024-04-30
申请号:US18381069
申请日:2023-10-17
发明人: Hany Mohamed Abd El-Lateef Ahmed , Mai Mostafa Khalaf Ali , Antar Ahmed Abdelhamid Ahmed , Amer A. Amer
IPC分类号: C07D249/12 , A61P31/04 , A61P31/10
CPC分类号: C07D249/12 , A61P31/04 , A61P31/10
摘要: An ethyl {[4-benzoyl-5-(3-fluorophenyl)-4H-1,2,4-triazol-3-yl]thio}acetate compound, its synthesis, and its use as an antimicrobial agent.
-
公开(公告)号:US20240025865A1
公开(公告)日:2024-01-25
申请号:US18037665
申请日:2021-11-18
发明人: Elizabetha Raguan Pen , Avi Monhait , Amir Ezion , Elijah Gelman , Ron Nisenblat
IPC分类号: C07D249/12 , C07C241/02 , C07D301/36
CPC分类号: C07D249/12 , C07C241/02 , C07D301/36
摘要: The present invention is directed to a process for the preparation of a hydrazine derivative by reaction of the corresponding oxirane with hydrazine, that uses as only solvent toluene. The process provides excellent yields and purities and allows to proceed without purification in a one-pot scheme. Toluene additionally reduces the excess of hydrazine needed to complete the reaction, significantly reducing the waste treatment costs and even allows the hydrazine to be recycled into the reaction.
-
公开(公告)号:US11851443B2
公开(公告)日:2023-12-26
申请号:US17579457
申请日:2022-01-19
发明人: Roland Gendron , Melissa Fleury , Adam D. Hughes
IPC分类号: C07D498/08 , C07D213/81 , C07D231/14 , C07D233/26 , C07D233/90 , C07D237/24 , C07D239/34 , C07D241/24 , C07D249/04 , C07D249/10 , C07D249/18 , C07D257/04 , C07D261/20 , C07D263/34 , C07D271/06 , C07D277/56 , C07D307/68 , C07D333/70 , C07D401/04 , C07D401/06 , C07D403/04 , C07D403/06 , C07D405/12 , C07D409/06 , C07D471/04 , C07D498/04 , C07D261/18 , C07D207/34 , C07D239/36 , C07D413/06 , A61K31/42 , A61K31/422 , A61K31/5377 , A61K45/06 , C07D413/04 , C07D413/12 , C07D213/79 , C07D213/80 , C07D237/04 , C07D249/08 , C07D249/12 , C07D261/12 , C07D263/56 , C07D277/46 , C07D333/40
CPC分类号: C07D498/08 , A61K31/42 , A61K31/422 , A61K31/5377 , A61K45/06 , C07D207/34 , C07D213/79 , C07D213/80 , C07D213/81 , C07D231/14 , C07D233/26 , C07D233/90 , C07D237/04 , C07D237/24 , C07D239/34 , C07D239/36 , C07D241/24 , C07D249/04 , C07D249/08 , C07D249/10 , C07D249/12 , C07D249/18 , C07D257/04 , C07D261/12 , C07D261/18 , C07D261/20 , C07D263/34 , C07D263/56 , C07D271/06 , C07D277/46 , C07D277/56 , C07D307/68 , C07D333/40 , C07D333/70 , C07D401/04 , C07D401/06 , C07D403/04 , C07D403/06 , C07D405/12 , C07D409/06 , C07D413/04 , C07D413/06 , C07D413/12 , C07D471/04 , C07D498/04
摘要: In one aspect, the invention relates to compounds having the formula:
where R1-R6, a, b, and X are as defined in the specification, or a pharmaceutically acceptable salt thereof. These compounds have neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising such compounds; methods of using such compounds; and processes and intermediates for preparing such compounds.-
10.
公开(公告)号:US11789025B2
公开(公告)日:2023-10-17
申请号:US17080373
申请日:2020-10-26
IPC分类号: G01N33/68 , C07C225/14 , C07C233/33 , C07C255/60 , C07C321/04 , C07C321/14 , C07D209/34 , C07D211/70 , C07D219/04 , C07D233/88 , C07D241/04 , C07D249/12 , C07D265/30 , C07D265/34 , C07D265/36 , C07D295/185 , C07D307/54 , C07D401/04 , C07D401/12 , C07D401/14 , C07D403/04 , C07D403/12 , C07D471/04 , C07D487/04 , C07D498/06
CPC分类号: G01N33/6848 , C07C225/14 , C07C233/33 , C07C255/60 , C07C321/04 , C07C321/14 , C07D209/34 , C07D211/70 , C07D219/04 , C07D233/88 , C07D241/04 , C07D249/12 , C07D265/30 , C07D265/34 , C07D265/36 , C07D295/185 , C07D307/54 , C07D401/04 , C07D401/12 , C07D401/14 , C07D403/04 , C07D403/12 , C07D471/04 , C07D487/04 , C07D498/06 , G01N2560/00
摘要: The present application relates to mass spectrometry methods for use in identifying proteins or other biomolecules which are bound irreversibly by test compounds.
-
-
-
-
-
-
-
-
-