摘要:
A method for the automatic chromatography of thin-layer plates for thin-layer chromatography with a development chamber 1 in which a thin-layer plate D is completely enclosed, sealed-off and isolated from the external environment. In the development chamber, a front space containing an inner atmosphere is located on the front face of the separation layer of the thin-layer plate. The depth of the front space is about 2 mm and a maximum 3 mm. An inlet is provided at one end of the front space and an outlet is provided at the other end of the front space. During the chromatographic development, a stream of gas of particular composition determined by the user is created throughout the entire front space, the entire inner atmosphere being set in motion, without stagnant or stationary gas phase.
摘要:
An ultrathin-layer chromatography plate having a stationary phase with electrospun nanofibers comprising silica, wherein the stationary phase has a thickness from about 10 μm to about 30 μm.
摘要:
A method for sequentially performing a synthesis, separation and screening of chemical entities, especially a combinatorial library, is described. The method utilises a bulk of a stationary phase (e.g. silica gel, aluminium oxide, cellulose, etc. for example arranged on a backing) for the performance of the synthesis, separation and screening. The technique described enables a rapid route from synthesis to the testing of chemical compounds. Screening can be performed without need for reaction work-up. Preferred screening methods are those used to determine the biological activity of the compounds.
摘要:
A separating material for thin-layer chromatography, comprising a substrate material coated with a thin sorbent layer, wherein the sorbent layer optionally contains a binder, an indicator, or both, is improved in that the sorbent layer has a surface modified by reacting the sorbent layer with a silanizing agent without the exclusion of moisture.
摘要:
A process for increasing the resistance to water of a chromatographic sorbent layer coated onto a support and comprising a binder of (a) salt(s) of (a) polyacrylic acid(s) and/or polymethacrylic acid(s), comprises treating the coated sorbent layer with an acid and then washing and drying the acid treated layers. The thus-prepared chromatographic materials are not only highly water resistant but also have an advantageously low impurity content.
摘要:
A thin layer medium for use in molecular diffusion or affinity separation processes having a layer of hydrated gel material, the surface of which is scored or cross-scored at intervals of 0.05 to 1 millimeter. The medium may be maintained wet until used or it may be dried for storage and rehydrated before use.
摘要:
COATED FILMS SUITABLE FOR LAYER CHROMATOGRAPHY ARE OBTAINED BY APPLYING THE ADSORBENT COATING TO A POLYESTER OR OTHER FLEXIBLE PLASTIC FILM WHOSE SURFACE IS COVERED WITH A THIN COHERENT COATING OF POLYMERIC TITANIUM DIOXIDE AND/ OR POLYMERIC ZIRCONIUM DIOXIDE.
摘要:
THIN-LAYER CHROMATOGRAPHIC PLATES ARE PROVIDED WITH TWO LAYERS, ONE FOR THE REMOVAL OF INTERFERING CONSTITUENTS AND THE OTHER FOR THE SEPARATION OF AMINO ACIDS.
摘要:
IMPROVED TLC RESOLUTIONS ARE OBTAINED ON PLATES ON WHICH THE THICKNESS OF THE CONTINUOUS ADSORBENT LAYER IS ABRUPTLY INCREASED BY A FACTOR OF ABOUT FOUR OR FIVE TO PRIVIDE A NARROW, DEEPLY COATED ZONE THAT INCREASES THE UPTAKE OF SOLVENT. A SPREADER FOR READILY PREPARING THE DUAL THICKNESS PLATES ALSO IS DESCRIBED.