公开(公告)号：US11629435B2

公开(公告)日：2023-04-18

申请号：US17897769

申请日：2022-08-29

申请人： SHAANXI ENVIRONMENTAL PROTECTION RESEARCH INSTITUTE ,  SHAANXI RONGNA MATERIAL TECHNOLOGY CO., LTD.

发明人： Feng Ji ,  Min Zhang ,  Dong Li ,  Yifan Lei ,  Qingyi Wang ,  Jundong Wang ,  Hongbo Li

IPC分类号： D01D1/02 ,  D01F8/08 ,  D01F8/10 ,  D01F8/14 ,  D01F4/02 ,  D01D5/00

摘要： An electrospun nanofiber membrane and a method for preparing the electrospun nanofiber membrane are provided to solve problems of poor mechanical properties, short service life, poor uniformity and consistency of orientation of fibers and poor stability of fiber networks in current electrospun composite nanofiber materials. The electrospun nanofiber membrane is prepared by spinning solution through a high-voltage electrospinning device. The spinning solution is blending solution of regenerated silk fibroin:polyvinyl alcohol:polylactic acid with a mass ratio being 75-85:10-20:5 dissolved in a mixed solvent of trifluoroacetic acid and dichloromethane with a volume ratio being 7:3. The method establishes a reasonable mass ratio parameter of the regenerated silk fibroin, the polyvinyl alcohol and the polylactic acid to blending spinning to improve spinnability of silk fibroin, as well as prepare the electrospun composite nanofiber membrane with good mechanical properties.

公开(公告)号：US20220235100A1

公开(公告)日：2022-07-28

申请号：US17617566

申请日：2020-06-09

申请人： Spiber Inc.

发明人： Hiroaki Suzumura ,  Yui Hirose

IPC分类号： C07K14/435 ,  D06M15/15 ,  D01F4/02 ,  C09D5/00 ,  C09D189/00 ,  C09D7/40 ,  C08J7/04 ,  C08J7/056

摘要： Provided is a water-absorbing and quick-drying property-imparting agent capable of easily imparting water-absorbing and quick-drying properties to various materials or articles in a simple process, and a method capable of easily imparting water-absorbing and quick-drying properties to predetermined materials or articles.
A water-absorbing and quick-drying property-imparting agent containing modified fibroin as an active ingredient, and a method for imparting water-absorbing and quick-drying properties to an article, the method including a step of incorporating modified fibroin into the article.

公开(公告)号：US20210032782A1

公开(公告)日：2021-02-04

申请号：US17044436

申请日：2019-04-03

申请人： Hasetora Spinning Co., Ltd. ,  Spiber Inc.

发明人： Tetsuhiro Asano ,  Akihiko Ozeki

IPC分类号： D02G3/04 ,  D01F4/02 ,  D03D15/00 ,  D04B1/14 ,  D06M11/01

摘要： The present invention aims at providing a blended yarn with which a knitted or woven body, wherein a decrease in tension and stiffness due to moistness is reduced, can be manufactured, even in a case where the blended yarn is used for the manufacture of the knitted or woven body; a knitted or woven body of the same; and a method for manufacturing the knitted or woven body. The blended yarn according to the present invention comprises a modified fibroin fiber and a regenerated cellulose fiber.

公开(公告)号：US20200207817A1

公开(公告)日：2020-07-02

申请号：US16633589

申请日：2018-07-25

申请人： Spiber Inc. ,  Riken

发明人： Keisuke Morita ,  Yunosuke Abe ,  Takehisa Maekawa ,  Koichi Kotaka ,  Junichi Sugahara ,  Keiji Numata

IPC分类号： C07K14/435 ,  D01F4/02 ,  C12N15/63

摘要： The present invention relates to a modified fibroin including a domain sequence represented by Formula 1: [(A)n motif-REP]m or Formula 2: [(A)n motif-REP]m-(A)n motif, in which the domain sequence has an amino acid sequence with a reduced content of a glutamine residue equivalent to an amino acid in which one or a plurality of glutamine residues in REP are deleted or substituted with other amino acid residues, as compared with a naturally occurring fibroin. [In Formula 1 and Formula 2, (A)n motif represents an amino acid sequence consisting of 4 to 27 amino acid residues, and the number of alanine residues with respect to the total number of amino acid residues in the (A)n motif is 80% or more. REP represents an amino acid sequence consisting of 10 to 200 amino acid residues. m represents an integer of 10 to 300. A plurality of (A)n motifs may be the same amino acid sequence or different amino acid sequences.]

公开(公告)号：US20190292688A1

公开(公告)日：2019-09-26

申请号：US16319468

申请日：2017-08-01

申请人： TRUSTEES OF TUFTS COLLEGE

发明人： Fiorenzo G. OMENETTO ,  Peter TSENG

IPC分类号： D01F4/02 ,  B82B1/00 ,  B82B3/00 ,  B82Y30/00 ,  B82Y40/00 ,  B81C99/00

摘要： This present disclosure provides methods for utilizing such forces in when generating nanofibrillar constructs with engineered morphology from the nano- to macro-scales. Using for example, a biopolymer silk fibroin as a base material, patterns an intermediate hydrogel were generated within a deformable mold. Subsequently, mechanical tension was introduced via either hydrogel contraction or mold deformation, and finally a material is reentrapped in this transformed shape via beta-sheet crystallization and critical point drying. Topdown engineered anchorages, cables, and shapes act in concert to mediate precision changes in nanofiber alignment/orientation and a macroscale form of provided nanofibrillar structure. An ability of this technique to engineer large gradients of nano- and micro-scale order, manipulate mechanical properties (such as plasticity and thermal transport), and the in-situ generation of 2D and 3D, multi-tiered and doped, nanofibrillar constructs was demonstrated.

公开(公告)号：US10280204B2

公开(公告)日：2019-05-07

申请号：US15046903

申请日：2016-02-18

申请人： TUFTS UNIVERSITY

发明人： David L. Kaplan ,  Fiorenzo Omenetto ,  Brian Lawrence ,  Mark Cronin-Golomb

IPC分类号： C07K14/435 ,  D01F4/02 ,  B29C39/02 ,  B29D11/00 ,  G01N33/543 ,  G02B1/04 ,  G02B6/138 ,  G02B1/06 ,  G01N33/544 ,  B82Y20/00 ,  G02B6/12 ,  G02B1/00 ,  G02B5/18

摘要： A method of manufacturing a biopolymer optical device includes providing a polymer, providing a substrate, casting the polymer on the substrate, and enzymatically polymerizing an organic compound to generate a conducting polymer between the provided polymer and the substrate. The polymer may be a biopolymer such as silk and may be modified using organic compounds such as tyrosines to provide a molecular-level interface between the provided bulk biopolymer of the biopolymer optical device and a substrate or other conducting layer via a tyrosine-enzyme polymerization. The enzymatically polymerizing may include catalyzing the organic compound with peroxidase enzyme reactions. The result is a carbon-carbon conjugated backbone that provides polymeric “wires” for use in polymer and biopolymer optical devices. An all organic biopolymer electroactive material is thereby provided that provides optical functions and features.

公开(公告)号：US20190093257A1

公开(公告)日：2019-03-28

申请号：US16141787

申请日：2018-09-25

申请人： Bolt Threads, Inc.

发明人： Amir Ahmad Bakhtiary Davijani ,  Steven Tom ,  Maxime Boulet-Audet ,  Paul Andre Guerette ,  Lindsay Wray ,  Nicole Elizabeth Subler ,  Zoya Nasir Zulfiqar ,  Hua Li ,  Jessica Wang

IPC分类号： D01D5/06 ,  D01F4/02 ,  D01D1/02 ,  D02J1/22

摘要： Provided herein are scalable methods of processing wet-spun fiber comprising recombinant spider silk polypeptides to generate a three-dimensional crystalline lattice of beta-sheet structures in the fiber.

公开(公告)号：US20190002644A1

公开(公告)日：2019-01-03

申请号：US16065391

申请日：2016-12-21

申请人： SPIBER INC.

发明人： Yoshinori OHTA ,  Hiroaki SUZUMURA

IPC分类号： C08J3/07 ,  C07K14/435 ,  D01F4/02

摘要： The present invention relates to a method for producing a polymer aggregate, the method including: a step for bringing a polymer solution containing a polymer substance and cations for gel formation into contact with an anion solution containing anions for gel formation to form a gel at an interface between the polymer solution and the anion solution; and a step for causing the polymer substance to aggregate inside the gel.

公开(公告)号：US20180080147A1

公开(公告)日：2018-03-22

申请号：US15564142

申请日：2016-04-04

申请人： SPIBER INC. ,  KOJIMA INDUSTRIES CORPORATION

发明人： Kana ISHIDA ,  Hironori YAMAMOTO ,  Hiroaki SUZUMURA ,  Kazuhide SEKIYAMA

IPC分类号： D01F4/02 ,  C07K14/435 ,  D01F1/02

CPC分类号： D01F4/02 ,  C07K14/435 ,  C07K14/43518 ,  D01C3/00 ,  D01F1/02

摘要： A polar solvent solution of the present invention is a polar solvent solution in which a solute containing a polyamino acid is dissolved in a polar solvent. The solution has a moisture content of less than 5 mass % based on 100 mass % of the solution. A method for producing a polar solvent solution of the present invention includes changing a moisture content of the solution to adjust the viscosity of the solution. Further, another method for producing a polar solvent solution includes reducing a moisture content of the solution to increase the viscosity of the solution. Thus, the present invention provides a polar solvent solution that enables stable spinning and casting without lowering its viscosity when used as dopes for spinning, film, etc., and methods for producing the same.

公开(公告)号：US09623147B2

公开(公告)日：2017-04-18

申请号：US14293308

申请日：2014-06-02

申请人： Trustees of Tufts College

发明人： David L. Kaplan ,  Ung-Jin Kim ,  Jaehyung Park ,  Hyoung-Joon Jin

IPC分类号： A61L27/22 ,  A61L27/36 ,  A61L27/38 ,  A61L27/52 ,  C07K14/435 ,  C08J3/07 ,  C08J3/075 ,  C08J5/18 ,  C08J9/00 ,  C08J9/26 ,  C08J9/28 ,  C08L89/00 ,  D01D5/00 ,  D01F4/02 ,  B29C39/00 ,  B29C39/20 ,  B29C55/00 ,  B29D7/01 ,  B29L7/00 ,  B29L9/00

CPC分类号： A61L27/227 ,  A61L27/3604 ,  A61L27/38 ,  A61L27/52 ,  A61L27/56 ,  A61L2430/02 ,  B29C39/003 ,  B29C39/203 ,  B29C55/005 ,  B29D7/01 ,  B29K2089/00 ,  B29L2007/00 ,  B29L2009/00 ,  C07K14/43536 ,  C07K14/43586 ,  C08J3/07 ,  C08J3/075 ,  C08J5/18 ,  C08J9/0061 ,  C08J9/26 ,  C08J9/28 ,  C08J2201/0444 ,  C08J2201/0504 ,  C08J2205/022 ,  C08J2389/00 ,  C08L89/00 ,  D01D5/0007 ,  D01F4/02 ,  Y10T428/249921 ,  Y10T442/10 ,  Y10T442/60

摘要： The present invention provides for concentrated aqueous silk fibroin solutions and an all-aqueous mode for preparation of concentrated aqueous fibroin solutions that avoids the use of organic solvents, direct additives, or harsh chemicals. The invention further provides for the use of these solutions in production of materials, e.g., fibers, films, foams, meshes, scaffolds and hydrogels.