公开(公告)号：US10562875B2

公开(公告)日：2020-02-18

申请号：US16079751

申请日：2017-02-27

Applicant: Nederlandse Organisatie voor toegepast-natuurwetenschappelijk onderzoek TNO

Inventor： Marc Crockatt ,  Jan Harm Urbanus

IPC: C07D307/89 ,  C07C37/56 ,  C07C45/51 ,  C07C249/12 ,  C07C249/16 ,  C07C51/27 ,  C07D307/52 ,  C07C39/04 ,  C07C47/54 ,  C07C63/307 ,  C07C251/48 ,  C07C251/86 ,  C07B37/12

Abstract: Described are methods for preparing phenols, benzene carboxylic acids, esters and anhydrides thereof from furanic compounds by reaction with a dienophile, wherein the furanic compounds are reacted with a hydrazine and/or oxime and then reacted with a dienophile.

公开(公告)号：US5395766A

公开(公告)日：1995-03-07

申请号：US968311

申请日：1992-10-29

Applicant: Yasuyuki Koizumi ,  Naoyuki Yoshida ,  Teruyo Sugiura ,  Kazutoshi Miyazawa

Inventor： Yasuyuki Koizumi ,  Naoyuki Yoshida ,  Teruyo Sugiura ,  Kazutoshi Miyazawa

IPC: C07D309/12 ,  C07C37/56 ,  C07C39/17 ,  C07C41/26 ,  C07C43/23 ,  C07C43/253 ,  C07C67/03 ,  C07C69/013 ,  C07C69/03 ,  C07D453/02 ,  C07F7/18 ,  C12P41/00 ,  C07D315/00 ,  C07C41/00 ,  C07C69/00

CPC classification number: C07C43/23 ,  C07C69/013 ,  C07D453/02 ,  C07C2101/14

Abstract: The present invention provides an optically active trans-2-aryl-1-cyclohexanol derivative represented by the following general formula (I). ##STR1## The compounds can be obtained by transesterifiation reaction of the following compound (II) as a starting material with lipase. ##STR2## The optically active trans-2-aryl-1-cyclohexanol derivative can be used as an asymmetric source of asymmetric Diels-Alder reaction or a starting material of physiological active materials.

Abstract translation: 本发明提供由以下通式（I）表示的光学活性的反式-2-芳基-1-环己醇衍生物。 以下化合物（II）作为原料与脂肪酶的反应反应。 （II）光学活性的反式-2-芳基-1-环己醇衍生物可用作不对称狄尔斯 - 阿尔德反应的不对称来源或生理活性物质的原料。

公开(公告)号：US5364983A

公开(公告)日：1994-11-15

申请号：US133660

申请日：1993-10-07

Applicant: Laurent Weisse ,  Heinz Strutz

Inventor： Laurent Weisse ,  Heinz Strutz

IPC: B01J31/02 ,  C07B61/00 ,  C07C37/56 ,  C07C39/08 ,  C07C37/00

CPC classification number: C07C37/56

Abstract: The present invention relates to a process for the preparation of aromatic polyhydroxy compounds, by reacting an aromatic hydroxyaldehyde with hydrogen peroxide, with or without the addition of a base, in the presence of a nitrile R--CN, in which R is an alkyl radical having 1 to 4 carbon atoms or a phenyl radical, which is unsubstituted or substituted by one or more alkyl groups.

Abstract translation: 本发明涉及一种制备芳族多羟基化合物的方法，其中芳基羟基醛与过氧化氢在碱存在或不加入下，在腈R-CN存在下反应，其中R是烷基 具有1至4个碳原子或苯基，其未被取代或被一个或多个烷基取代。

公开(公告)号：US4620043A

公开(公告)日：1986-10-28

申请号：US788276

申请日：1985-10-17

Applicant: Chiu T. Lam ,  David M. Shannon

Inventor： Chiu T. Lam ,  David M. Shannon

IPC: B01J27/18 ,  B01J27/185 ,  B01J27/186 ,  C07C37/56 ,  C07C37/00

CPC classification number: C07C37/56 ,  B01J27/1817 ,  B01J27/1853 ,  B01J27/186 ,  Y02P20/52

Abstract: Multicomponent catalysts comprising copper, a metal selected from the group consisting of vanadium, chromium, manganese, iron, cobalt, nickel and zinc; and phosphate are employed for oxidizing an aromatic carboxylic acid to the corresponding phenol, e.g., benzoic acid to phenol.

Abstract translation: 包含铜，选自钒，铬，锰，铁，钴，镍和锌的金属的多组分催化剂; 和磷酸盐用于将芳族羧酸氧化成相应的苯酚，例如苯甲酸至苯酚。

公开(公告)号：US3927123A

公开(公告)日：1975-12-16

申请号：US21020871

申请日：1971-12-20

Applicant: RHONE POULENC SA

Inventor： BOURDIN FRANCOIS ,  CHIZAT FRANCOIS ,  COSTANTINI MICHEL ,  JOUFFRET MICHEL

IPC: C07C37/56 ,  C07C27/00 ,  C07C37/00 ,  C07C67/44

CPC classification number: C07C37/56 ,  C07C39/07 ,  C07C39/06

Abstract: Phenols nuclear substituted by 1 to 3 straight-chain or branched-chain alkyl substituents of 1 to 10 carbons are prepared by oxidizing the aldehyde group of the corresponding alkyl substituted benzaldehyde with an organic peracid, which is derived from a carboxylic acid of pKa in water less than 4. The formate ester of the phenol, which may be in the reaction product, is hydrolysed or transesterified to form the phenol.

Abstract translation: 通过用有机过酸氧化相应的烷基取代的苯甲醛的醛基来制备由1至3个具有1至10个碳原子的直链或支链烷基取代基取代的酚，该有机过酸衍生自在水中的pKa的羧酸 可以在反应产物中的酚的甲酸酯被水解或酯交换以形成苯酚。

公开(公告)号：US3365503A

公开(公告)日：1968-01-23

申请号：US34917764

申请日：1964-03-03

Applicant: MONTEDISON SPA

Inventor： ALDO FORNI ,  PIERO RAMELLO ,  LUIGI CAVALLI

IPC: C07C37/56

CPC classification number: C07C37/56 ,  C07C39/04

公开(公告)号：US11439968B2

公开(公告)日：2022-09-13

申请号：US16915405

申请日：2020-06-29

Applicant: Ardent Life Inc.

Inventor： Shanel A. Lindsay

IPC: A61K36/185 ,  B01J6/00 ,  C07D311/80 ,  C07D311/78 ,  C07C37/50 ,  B01J19/24 ,  B01L7/00 ,  B01J19/00 ,  C07C37/56

Abstract: A waterless decarboxylation device used to decarboxylate cannabis is described. For example, the device could include a product container to contain an amount of raw cannabis plant material, a heating container configured to surround and contact the product container, a heater in contact with the heating container, a foam layer surrounding the product container and heating container, at least one sensor configured to detect the temperature of the heating container, a lid that encloses the product container and fluidly seals it from the environment, and a controller configured to control power to the heater in response to signals sent from the at least one sensor indicating whether the heating container has reached a threshold temperature.

公开(公告)号：US11254633B2

公开(公告)日：2022-02-22

申请号：US16602455

申请日：2019-10-07

Applicant: Jonas Alcirdas Navickas

Inventor： Jonas Alcirdas Navickas

IPC: C07C39/205 ,  C07C37/56 ,  C07D311/80 ,  A61K31/05

Abstract: Dried and or decarboxylated cannabis containing a known composition of cannabinoids is blended with other dried or decarboxylated cannabis of a known composition of cannabinoids and or mixed with other extracts of, isolates of, cannabisor synthetic cannabinoids to achieve a prescribed amount of cannabinoids in the blend. Decarboxylated cannabis is preferentially produced using controlled thin layer decarboxylation. Precision decarboxylation is optionally used to produce a precise pair ratio of acidic to neutral cannabinoid, eg THCA to THC or CBDA to CBD. Further a prescribed or selected terpene profile is mixed and applied to the blend. Once mixed the plant material is suitable for ingestion without further treatment and is dosed appropriately.

公开(公告)号：US10919829B2

公开(公告)日：2021-02-16

申请号：US16445264

申请日：2019-06-19

Applicant: KANEKA CORPORATION

Inventor： Koji Machida ,  Hiroaki Yasukouchi ,  Akira Nishiyama

IPC: C07C37/74 ,  B01D3/14 ,  B01D15/36 ,  B01J41/12 ,  C07C37/56 ,  C07H1/06 ,  C07D249/08 ,  C07C69/12 ,  C07C33/22 ,  C07C67/03 ,  C07B61/00

Abstract: A high-purity alcohol compound can be obtained by a method comprising passing a solution containing an ester compound and methanol and/or ethanol through a column packed with an anion exchange resin having methoxide and/or ethoxide as a counter anion to generate a methyl ester and/or ethyl ester, and distilling off the methyl ester and/or ethyl ester together with the methanol and/or ethanol.

公开(公告)号：US5120884A

公开(公告)日：1992-06-09

申请号：US655875

申请日：1991-02-14

Applicant: P. J. Thomas ,  R. Garth Pews

Inventor： P. J. Thomas ,  R. Garth Pews

IPC: C07C37/56 ,  C07C39/17

CPC classification number: C07C37/56 ,  C07C2102/06

Abstract: Hydroxy arylcyclobutenes are prepared by the Baeyer-Villiger oxidation of arylcyclobutene aldehydes with permonophosphoric acid.

Abstract translation: 羟基芳基环丁烯通过Baeyer-Villiger氧化芳基环丁烯醛与permonophosphoric酸制备。