公开(公告)号：US09494527B2

公开(公告)日：2016-11-15

申请号：US13713864

申请日：2012-12-13

Applicant: Step Ahead Innovations, Inc.

Inventor： James E. Clark

IPC: G01N21/15 ,  G01N21/88 ,  G01N21/77 ,  C02F1/00 ,  G01N33/18 ,  G01N21/85 ,  F21V8/00 ,  G01N21/78 ,  G01N31/22 ,  A01K63/04 ,  G01N21/64

CPC classification number: G01N21/77 ,  A01K63/04 ,  C02F1/008 ,  C02F2103/42 ,  C02F2209/005 ,  C02F2209/006 ,  C02F2209/008 ,  C02F2209/06 ,  C02F2209/14 ,  C02F2209/15 ,  C02F2209/18 ,  G01N21/15 ,  G01N21/6428 ,  G01N21/78 ,  G01N21/8507 ,  G01N21/88 ,  G01N31/22 ,  G01N33/18 ,  G01N2021/758 ,  G01N2021/7786 ,  G01N2021/7793 ,  G01N2201/127 ,  G02B6/0001 ,  Y10S436/805 ,  Y10S436/809 ,  Y10T436/11 ,  Y10T436/115831 ,  Y10T436/12 ,  Y10T436/173076 ,  Y10T436/173845 ,  Y10T436/174614 ,  Y10T436/175383 ,  Y10T436/193333 ,  Y10T436/207497 ,  Y10T436/25 ,  Y10T436/25375

Abstract: Cleaning systems for optics of optical readers to periodically clean one or more surfaces of the optics of matter that may deposit on surface(s) and that might interfere with the performance of the reader. In an example, the cleaning system is used on a chemical indicator apparatus that includes one or more chemical indicators that are read by an optical reader having an optic. During use, the chemical indicator apparatus is moved relative optic during a reading mode. A cleaning element is engaged with the chemical indicator apparatus so as to have a neutral position in which it cannot contact the optic during the reading mode. When it is desired to clean the optic, the chemical indicator apparatus is moved in a manner that causes the cleaning element to move from the neutral position to a deployed position in which it contacts the optic in a manner that cleans the optic as the apparatus continues to be moved.

Abstract translation: 用于光学读取器的光学系统的清洁系统周期性地清洁可能沉积在表面上并且可能干扰读取器的性能的物质光学元件的一个或多个表面。 在一个示例中，清洁系统用于化学指示器装置，其包括由具有光学元件的光学读取器读取的一个或多个化学指示器。 在使用期间，在读取模式期间，化学指示器装置相对于光学元件移动。 清洁元件与化学指示器装置接合，以便具有在读取模式期间其不能接触光学元件的中性位置。 当需要清洁光学元件时，化学指示器装置以使得清洁元件从中立位置移动到展开位置的方式移动，在该展开位置中，该化学指示器装置以与装置相连的方式清洁光学元件的方式移动 被移动

公开(公告)号：US20140011287A1

公开(公告)日：2014-01-09

申请号：US14008141

申请日：2012-03-27

Applicant: Evan K.L.Y. Hajime ,  Myungchan Kang

Inventor： Evan K.L.Y. Hajime ,  Myungchan Kang

IPC: G01N31/22

CPC classification number: G01N31/222 ,  G01N21/81 ,  G01N31/22 ,  G01N2021/758 ,  G01N2021/7773

Abstract: Compositions that include bis(glyoxime)-transition metal complexes bound to metal oxide solid supports are provided. In some embodiments the compositions include nickel dimethylglyoxime and the metal oxide supports can be alumina or silica. These compositions can be used to make a colorimetric moisture-indicating sensor that changes visible reflection spectrum quantitatively and reversibly according to the amount of moisture in contact with the sensor. Also provided is a method of detecting moisture using the provided compositions.

Abstract translation: 提供了包含与金属氧化物固体支持物结合的双（乙二肟） - 过渡金属络合物的组合物。 在一些实施方案中，组合物包括二甲基二肟二甲基镍，并且金属氧化物载体可以是氧化铝或二氧化硅。 这些组合物可以用于制备比色湿度指示传感器，其根据与传感器接触的水分量定量和可逆地改变可见反射光谱。 还提供了使用所提供的组合物检测水分的方法。

公开(公告)号：US20110141431A1

公开(公告)日：2011-06-16

申请号：US13057810

申请日：2009-08-27

Applicant: Pamela Ann Jordan

Inventor： Pamela Ann Jordan

IPC: G01N21/00

CPC classification number: G01N21/75 ,  G01N21/21 ,  G01N33/54373 ,  G01N2021/758

Abstract: The present invention relates to a liquid crystal device for detecting interactions between a surface and an analyte. Specifically it provides a device for detecting interactions between a surface and an analyte, said device comprising a first substrate having an active surface supporting one or more first analyte(s), a second substrate, and a liquid crystal disposed on the active surface between the first substrate and second substrate, wherein the liquid crystal has a cross-section of varying thickness, wherein the cross-section of the liquid crystal has a first thickness and second thickness that is different to the first thickness, whereby the interaction between the active surface and the first analyte causes the orientation of the liquid crystal to change at a first critical thickness that is between the first and second thicknesses of the liquid crystal.

Abstract translation: 本发明涉及一种用于检测表面和分析物之间的相互作用的液晶装置。 具体地说，它提供了一种用于检测表面和分析物之间的相互作用的装置，所述装置包括第一衬底，其具有支撑一个或多个第一分析物的活性表面，第二衬底和布置在活性表面上的液晶 第一基板和第二基板，其中所述液晶具有不同厚度的横截面，其中所述液晶的横截面具有与所述第一厚度不同的第一厚度和第二厚度，由此所述有源表面 并且第一分析物导致液晶的取向在液晶的第一和第二厚度之间的第一临界厚度处变化。

公开(公告)号：US07923678B2

公开(公告)日：2011-04-12

申请号：US11572223

申请日：2005-07-19

Applicant: Christopher Robin Lowe ,  Jeffrey Blyth ,  Anthony Peter James

Inventor： Christopher Robin Lowe ,  Jeffrey Blyth ,  Anthony Peter James

IPC: G01J1/04 ,  G01B11/16 ,  G03H1/00

CPC classification number: G01N21/75 ,  G01N21/4788 ,  G01N2021/758 ,  G03H2001/0044

Abstract: A sensing method, which comprises subjecting a holographic sensor to an external physical interaction to which the sensor is sensitive, and observing a change in the holographic image.

Abstract translation: 一种感测方法，其包括对全息传感器进行传感器敏感的外部物理相互作用，并观察全息图像的变化。

公开(公告)号：US20070110614A1

公开(公告)日：2007-05-17

申请号：US11507032

申请日：2006-08-18

Applicant: Nicholas Abbott ,  Rahul Shah

Inventor： Nicholas Abbott ,  Rahul Shah

IPC: G01N31/22

CPC classification number: B82Y15/00 ,  B82Y30/00 ,  G01N21/21 ,  G01N21/75 ,  G01N2021/758 ,  G02F1/133719 ,  Y10S436/805

Abstract: A device for detecting a compound in a sample includes a substrate and a self-assembled monolayer. The substrate includes a support with a metallized top surface, and the self-assembled monolayer includes an alkanethiol attached to the metallized top surface of the substrate and having a functional group that reversibly or irreversibly interacts with the compound. A liquid crystal is disposed on the self-assembled monolayer opposite the side of the self-assembled monolayer attached to the metallized top surface of the substrate. The liquid crystal includes a moiety that interacts with the functional group of the alkanethiol. When the compound is present in a sample that contacts the self-assembled monolayer, the orientation of the liquid crystal is altered.

Abstract translation: 用于检测样品中化合物的装置包括基底和自组装单层。 衬底包括具有金属化顶表面的支撑体，并且自组装单层包括连接到衬底的金属化顶表面的链烷硫醇并具有与化合物可逆地或不可逆地相互作用的官能团。 将液晶设置在与组装在衬底的金属化顶表面上的自组装单层侧相对的自组装单层上。 液晶包括与烷硫醇的官能团相互作用的部分。 当化合物存在于与自组装单层接触的样品中时，液晶的取向发生变化。

公开(公告)号：US5337376A

公开(公告)日：1994-08-09

申请号：US49461

申请日：1993-04-19

Applicant: Robert G. Ravetti ,  Thomas K. Dougherty

Inventor： Robert G. Ravetti ,  Thomas K. Dougherty

IPC: G01N21/27 ,  G01N21/75 ,  G01N21/77 ,  G01N21/78 ,  G01N21/80 ,  G01N21/85 ,  G02B6/00 ,  G02B6/02 ,  G02B6/36 ,  G02B5/14

CPC classification number: G02B6/02033 ,  G01N21/7703 ,  G01N2021/758 ,  G01N21/80 ,  G01N21/8507 ,  G02B6/14 ,  G02B6/4457

Abstract: A chemically sensitive sensor capable of detecting changes in concentrations of ions, atoms, or molecules in a fluid environment in which the sensor is immersed or embedded comprises a thin clad optical fiber, which is coated with a polymer which is permeable to liquids and which contains a chemically sensitive material, and a light carrying fiber. The polymeric material has the ability to change color and/or absorbance when the concentration of the ion, atom, or molecule in the surrounding environment changes. The polymer will return to its original color and/or absorbance state once the concentration goes back to the original value. The color change or absorbance is detected through the core of the optical fiber which is connected to a photodetector. The coupling of the light into the sensing structure is obtained by using a core-only optical fiber, surrounded by a clad material, in addition to an external light source. Coupling of the external light beam with the polymeric coated fiber is obtained through microbending losses in reverse by spooling the coated fiber around the clad material. Changes such as pH, metal or other ion concentration, organic molecule concentration, and gas molecule concentration may be detected.

Abstract translation: 能够检测传感器浸入或嵌入的流体环境中的离子，原子或分子的浓度变化的化学敏感传感器包括薄的包覆光纤，其涂覆有可渗透液体的聚合物，其包含 化学敏感材料和轻载纤维。 当周围环境中的离子，原子或分子的浓度变化时，聚合物材料具有改变颜色和/或吸光度的能力。 一旦浓度恢复到原始值，聚合物将恢复到其原始颜色和/或吸光度状态。 通过连接到光电检测器的光纤的芯检测颜色变化或吸光度。 除了外部光源之外，通过使用由包层材料包围的仅芯的光纤获得光耦合到感测结构中。 外部光束与聚合物涂覆纤维的耦合是通过将包覆的纤维缠绕在包覆材料上的缠绕而获得的，通过微弯曲损失来反向。 可以检测pH，金属或其他离子浓度，有机分子浓度和气体分子浓度等变化。

公开(公告)号：US20160258915A1

公开(公告)日：2016-09-08

申请号：US15153076

申请日：2016-05-12

Applicant: 3M INNOVATIVE PROPERTIES COMPANY

Inventor： Evan Koon Lun Yuuji Hajime ,  Myungchan Kang

IPC: G01N31/22 ,  G01N21/81

CPC classification number: G01N31/222 ,  G01N21/81 ,  G01N31/22 ,  G01N2021/758 ,  G01N2021/7773

Abstract: Compositions that include bis(glyoxime)-transition metal complexes bound to metal oxide solid supports are provided. In some embodiments the compositions include nickel dimethylglyoxime and the metal oxide supports can be alumina or silica. These compositions can be used to make a colorimetric moisture-indicating sensor that changes visible reflection spectrum quantitatively and reversibly according to the amount of moisture in contact with the sensor. Also provided is a method of detecting moisture using the provided compositions.

Abstract translation: 提供了包含与金属氧化物固体支持物结合的双（乙二肟） - 过渡金属络合物的组合物。 在一些实施方案中，组合物包括二甲基二肟二甲基镍，并且金属氧化物载体可以是氧化铝或二氧化硅。 这些组合物可以用于制备比色湿度指示传感器，其根据与传感器接触的水分量定量和可逆地改变可见反射光谱。 还提供了使用所提供的组合物检测水分的方法。

公开(公告)号：US20140019060A1

公开(公告)日：2014-01-16

申请号：US13713818

申请日：2012-12-13

Applicant: Step Ahead Innovations, Inc.

Inventor： James E. Clark

IPC: G01N33/18 ,  G01N31/22

CPC classification number: G01N21/77 ,  A01K63/04 ,  C02F1/008 ,  C02F2103/42 ,  C02F2209/005 ,  C02F2209/006 ,  C02F2209/008 ,  C02F2209/06 ,  C02F2209/14 ,  C02F2209/15 ,  C02F2209/18 ,  G01N21/15 ,  G01N21/6428 ,  G01N21/78 ,  G01N21/8507 ,  G01N21/88 ,  G01N31/22 ,  G01N33/18 ,  G01N2021/758 ,  G01N2021/7786 ,  G01N2021/7793 ,  G01N2201/127 ,  G02B6/0001 ,  Y10S436/805 ,  Y10S436/809 ,  Y10T436/11 ,  Y10T436/115831 ,  Y10T436/12 ,  Y10T436/173076 ,  Y10T436/173845 ,  Y10T436/174614 ,  Y10T436/175383 ,  Y10T436/193333 ,  Y10T436/207497 ,  Y10T436/25 ,  Y10T436/25375

Abstract: Methods of assisting human users with dosing of aquatic environments, such as aquariums, pools, hot tubs, ponds, etc., that utilize automated monitoring systems that continually monitor various parameters of the water in the aquatic environments. When one or more measured water parameters of an aquatic environment are out of tolerance, a dosing calculator uses water-quality information from a monitoring system to generate dosing instructions for a human user that instruct the user how to dose the aquatic environment with one or more additives that will put the one or more parameters back into tolerance. In some embodiments, input from a user is used to switch the monitoring system to a dosing mode from a normal monitoring mode to track the progress of the dosing more closely than the normal monitoring mode would.

Abstract translation: 使用自动监测系统来协助人类用水量的水族环境（如水族馆，游泳池，热水池，池塘等）的方法，这些监测系统不断地监测水生环境中的各种水参数。 当水环境的一个或多个测量的水参数超出公差时，计量计算器使用来自监测系统的水质信息为人类用户产生剂量指令，指示用户如何用一个或多个 将一个或多个参数重新纳入公差的添加剂。 在一些实施例中，来自用户的输入用于将监测系统从正常监测模式切换到计量模式，以跟踪正常监测模式将更接近剂量的进展。

公开(公告)号：US20140017801A1

公开(公告)日：2014-01-16

申请号：US13713773

申请日：2012-12-13

Applicant: STEP AHEAD INNOVATIONS, INC.

Inventor： James E. Clark

IPC: G01N21/78

CPC classification number: G01N21/77 ,  A01K63/04 ,  C02F1/008 ,  C02F2103/42 ,  C02F2209/005 ,  C02F2209/006 ,  C02F2209/008 ,  C02F2209/06 ,  C02F2209/14 ,  C02F2209/15 ,  C02F2209/18 ,  G01N21/15 ,  G01N21/6428 ,  G01N21/78 ,  G01N21/8507 ,  G01N21/88 ,  G01N31/22 ,  G01N33/18 ,  G01N2021/758 ,  G01N2021/7786 ,  G01N2021/7793 ,  G01N2201/127 ,  G02B6/0001 ,  Y10S436/805 ,  Y10S436/809 ,  Y10T436/11 ,  Y10T436/115831 ,  Y10T436/12 ,  Y10T436/173076 ,  Y10T436/173845 ,  Y10T436/174614 ,  Y10T436/175383 ,  Y10T436/193333 ,  Y10T436/207497 ,  Y10T436/25 ,  Y10T436/25375

Abstract: Photo-aging monitoring of light-based chemical indicators that experience performance degradation as the cumulative amount of light exposure from measurement and/or reference illumination increases from usage. Differing regions on a chemical indicator are illuminated with measurement illumination light of differing exposures, for example, higher brightness, longer exposure times, or both. Readings from the differing regions are compared with known aging information for the chemical indicator at issue to determine a confidence factor for the measurements. The confidence factor can be used to control various actions relating to measurements acquired from the chemical indicators, such as compensating measurement readings for photo-aging, assigning confidence levels to measurement readings, and issuing alerts to users when photo-aging exceeds one or more predetermined thresholds.

Abstract translation: 随着使用量的测量和/或参考照度的累积曝光量的增加，经历性能下降的基于光的化学指示剂的光老化监测。 用不同曝光的测量照明光照亮化学指示器上的不同区域，例如更高的亮度，更长的曝光时间或两者。 将来自不同区域的读数与所讨论的化学指标的已知老化信息进行比较，以确定测量的置信因子。 置信因子可用于控制与从化学指标获取的测量相关的各种动作，例如补偿光老化的测量读数，将置信度等级分配给测量读数，以及当光老化超过一个或多个预定值时向用户发出警报 阈值。

公开(公告)号：US20140017796A1

公开(公告)日：2014-01-16

申请号：US13713568

申请日：2012-12-13

Applicant: STEP AHEAD INNOVATIONS, INC.

Inventor： James E. Clark

IPC: G01N21/78

CPC classification number: G01N21/77 ,  A01K63/04 ,  C02F1/008 ,  C02F2103/42 ,  C02F2209/005 ,  C02F2209/006 ,  C02F2209/008 ,  C02F2209/06 ,  C02F2209/14 ,  C02F2209/15 ,  C02F2209/18 ,  G01N21/15 ,  G01N21/6428 ,  G01N21/78 ,  G01N21/8507 ,  G01N21/88 ,  G01N31/22 ,  G01N33/18 ,  G01N2021/758 ,  G01N2021/7786 ,  G01N2021/7793 ,  G01N2201/127 ,  G02B6/0001 ,  Y10S436/805 ,  Y10S436/809 ,  Y10T436/11 ,  Y10T436/115831 ,  Y10T436/12 ,  Y10T436/173076 ,  Y10T436/173845 ,  Y10T436/174614 ,  Y10T436/175383 ,  Y10T436/193333 ,  Y10T436/207497 ,  Y10T436/25 ,  Y10T436/25375

Abstract: An aquatic environment monitoring system that includes chemical indicators that are dyes immobilized in an immobilizing medium, such as a hydrogel, and supported on a holder such that an optical reader may be used to illuminate the indicator dyes. The chemical indicator dyes include chemical indicator dyes that are sensitive for detecting calcium, magnesium, and carbon dioxide present in the aquatic environment.

Abstract translation: 一种水生环境监测系统，其包括固定在诸如水凝胶的固定介质中的染料的化学指示剂，并且支撑在保持器上，使得光学读取器可用于照亮指示剂染料。 化学指示剂染料包括对于检测存在于水生环境中的钙，镁和二氧化碳敏感的化学指示剂染料。