公开(公告)号：US20190249205A1

公开(公告)日：2019-08-15

申请号：US16392756

申请日：2019-04-24

申请人： AJINOMOTO CO., INC.

发明人： Benjamin Mijts ,  Christine Roche ,  Peter Kelly ,  Sayaka Asari ,  Keita Fukui ,  Miku Toyazaki

IPC分类号： C12P7/24 ,  C12N1/20 ,  C12N9/10 ,  C12N9/88 ,  C12N9/02 ,  C12N9/04

CPC分类号： C12P7/24 ,  C12N1/20 ,  C12N9/0006 ,  C12N9/0008 ,  C12N9/0069 ,  C12N9/0073 ,  C12N9/1007 ,  C12N9/1085 ,  C12N9/88 ,  C12P7/22 ,  C12P7/42 ,  C12Y101/01001 ,  C12Y101/01025 ,  C12Y102/99007 ,  C12Y113/11003 ,  C12Y114/13082 ,  C12Y201/01015 ,  C12Y205/01054 ,  C12Y402/0101 ,  C12Y402/01118 ,  C12Y402/03004

摘要： A method for producing an objective substance such as vanillin and vanillic acid is provided. An objective substance is produced from a carbon source or a precursor of the objective substance by using a microorganism having an objective substance-producing ability, which microorganism has been modified so that the activity of an L-cysteine biosynthesis enzyme is increased.

公开(公告)号：US11807873B2

公开(公告)日：2023-11-07

申请号：US17504901

申请日：2021-10-19

申请人： Alliance for Sustainable Energy, LLC

发明人： Christopher W. Johnson ,  Allison Jean Zimont Werner ,  Gregg Tyler Beckham ,  Sandra Fabienne Notonier

IPC分类号： C12N9/02 ,  C12P7/44 ,  C12R1/39 ,  C12R1/40 ,  C12N1/20

CPC分类号： C12N9/0071 ,  C12N9/0069 ,  C12N9/0073 ,  C12P7/44 ,  C12N1/205 ,  C12R2001/39 ,  C12R2001/40 ,  C12Y114/13082

摘要： The present disclosure relates to a genetically modified microbial cell that includes a first genetic modification resulting in the expression of an exogenous vanillate demethylase, such that the microbial cell is capable of metabolizing an S-lignin decomposition product and producing 2-pyrone-4,6-dicarboxylate (PDC).

公开(公告)号：US20190249206A1

公开(公告)日：2019-08-15

申请号：US16392791

申请日：2019-04-24

申请人： AJINOMOTO CO., INC.

发明人： Benjamin Mijts ,  Christine Roche ,  Sayaka Asari ,  Miku Toyazaki ,  Keita Fukui

IPC分类号： C12P7/24 ,  C12R1/15 ,  C12R1/19 ,  C12N1/36

CPC分类号： C12P7/24 ,  C12N1/36 ,  C12N2330/50 ,  C12N2510/02 ,  C12P7/42 ,  C12P13/12 ,  C12R1/15 ,  C12R1/19 ,  C12Y101/01001 ,  C12Y101/01025 ,  C12Y113/11003 ,  C12Y114/13082

摘要： A method for producing an objective substance such as vanillin and vanillic acid is provided. An objective substance is produced from a carbon source or a precursor of the objective substance by using a microorganism having an objective substance-producing ability, which microorganism has been modified so that the activity of enolase is reduced.