公开(公告)号：US12077613B2

公开(公告)日：2024-09-03

申请号：US16970623

申请日：2019-02-19

申请人： COMPAGNIE INDUSTRIELLE DE LA MATIERE VEGETALE—CIMV

发明人： Bouchra Benjelloun Mlayah ,  Michel Delmas

IPC分类号： C08B37/00 ,  C07G1/00 ,  C13K1/02

CPC分类号： C08B37/0057 ,  C07G1/00 ,  C13K1/02

摘要： A method of production of lignin and hemicellulose from a plant lignocellulosic material includes (a) contacting a plant lignocellulosic material with an extraction solution during more than 2 hours at a temperature between 95° ° C. to 110° C., thereby obtaining a solid fraction and a liquid fraction, (b) separating the solid fraction and the liquid fraction, (c) concentrating the liquid fraction so as to obtain a concentrated liquid fraction, (d) mixing equal parts by weight of water with the concentrated liquid fraction so as to obtain a suspension comprising solid particles in suspension in a liquid medium, (e) separating the particles and the medium of the suspension, (f) recovering the particles of the suspension thereby obtaining a fraction comprising lignin called lignified fraction, (g) recovering the medium of the suspension thereby obtaining a fraction comprising hemicellulose called hemicellulosic fraction.

公开(公告)号：US20240247081A1

公开(公告)日：2024-07-25

申请号：US18437450

申请日：2024-02-09

申请人： GranBio Intellectual Property Holdings, LLC

发明人： Kimberly NELSON ,  Theodora RETSINA ,  Vesa PYLKKANEN ,  Ryan O'CONNOR

IPC分类号： C08B15/08 ,  C07G1/00 ,  C08B15/00 ,  C08B15/02 ,  C08B37/00 ,  C08H8/00 ,  C08L1/02 ,  C12P7/04 ,  C12P7/10 ,  C12P7/14 ,  C12P7/16 ,  C12P7/28 ,  C12P7/46 ,  C12P7/56 ,  C12P19/02 ,  C12P19/14 ,  C13K1/02 ,  D21C3/04 ,  D21C3/06 ,  D21C3/20 ,  D21C5/00 ,  D21C9/00 ,  D21C9/10 ,  D21C11/00 ,  D21H11/18

CPC分类号： C08B15/08 ,  C07G1/00 ,  C08B15/00 ,  C08B15/02 ,  C08B37/0057 ,  C08H8/00 ,  C08L1/02 ,  C12P7/04 ,  C12P7/10 ,  C12P7/14 ,  C12P7/16 ,  C12P7/28 ,  C12P7/46 ,  C12P7/56 ,  C12P19/02 ,  C12P19/14 ,  C13K1/02 ,  D21C3/04 ,  D21C3/06 ,  D21C3/20 ,  D21C5/00 ,  D21C5/005 ,  D21C9/002 ,  D21C9/007 ,  D21C9/10 ,  D21C11/0007 ,  D21H11/18 ,  C12P2201/00 ,  C12P2203/00 ,  Y02E50/10 ,  Y02P40/40

摘要： Processes disclosed are capable of converting biomass into high-crystallinity nanocellulose with surprisingly low mechanical energy input. In some variations, the process includes fractionating biomass with an acid (such as sulfur dioxide), a solvent (such as ethanol), and water, to generate cellulose-rich solids and a liquid containing hemicellulose and lignin; and mechanically treating the cellulose-rich solids to form nanofibrils and/or nanocrystals. The crystallinity of the nanocellulose material may be 80% or higher, translating into good reinforcing properties for composites. The nanocellulose material may include nanofibrillated cellulose, nanocrystalline cellulose, or both. In some embodiments, the nanocellulose material is hydrophobic via deposition of some lignin onto the cellulose surface. Optionally, sugars derived from amorphous cellulose and hemicellulose may be separately fermented, such as to monomers for various polymers. These polymers may be combined with the nanocellulose to form completely renewable composites.

公开(公告)号：US11932706B2

公开(公告)日：2024-03-19

申请号：US17163738

申请日：2021-02-01

申请人： GranBio Intellectual Property Holdings, LLC

发明人： Kimberly Nelson ,  Theodora Retsina ,  Vesa Pylkkanen ,  Ryan O'Connor

IPC分类号： C08B15/08 ,  C07G1/00 ,  C08B15/00 ,  C08B15/02 ,  C08B37/00 ,  C08H8/00 ,  C08L1/02 ,  C12P7/04 ,  C12P7/10 ,  C12P7/14 ,  C12P7/16 ,  C12P7/28 ,  C12P7/46 ,  C12P7/56 ,  C12P19/02 ,  C12P19/14 ,  C13K1/02 ,  D21C3/04 ,  D21C3/06 ,  D21C3/20 ,  D21C5/00 ,  D21C9/00 ,  D21C9/10 ,  D21C11/00 ,  D21H11/18

CPC分类号： C08B15/08 ,  C07G1/00 ,  C08B15/00 ,  C08B15/02 ,  C08B37/0057 ,  C08H8/00 ,  C08L1/02 ,  C12P7/04 ,  C12P7/10 ,  C12P7/14 ,  C12P7/16 ,  C12P7/28 ,  C12P7/46 ,  C12P7/56 ,  C12P19/02 ,  C12P19/14 ,  C13K1/02 ,  D21C3/04 ,  D21C3/06 ,  D21C3/20 ,  D21C5/00 ,  D21C5/005 ,  D21C9/002 ,  D21C9/007 ,  D21C9/10 ,  D21C11/0007 ,  D21H11/18 ,  C12P2201/00 ,  C12P2203/00 ,  Y02E50/10 ,  Y02P40/40

摘要： Processes disclosed are capable of converting biomass into high-crystallinity nanocellulose with surprisingly low mechanical energy input. In some variations, the process includes fractionating biomass with an acid (such as sulfur dioxide), a solvent (such as ethanol), and water, to generate cellulose-rich solids and a liquid containing hemicellulose and lignin; and mechanically treating the cellulose-rich solids to form nanofibrils and/or nanocrystals. The crystallinity of the nanocellulose material may be 80% or higher, translating into good reinforcing properties for composites. The nanocellulose material may include nanofibrillated cellulose, nanocrystalline cellulose, or both. In some embodiments, the nanocellulose material is hydrophobic via deposition of some lignin onto the cellulose surface. Optionally, sugars derived from amorphous cellulose and hemicellulose may be separately fermented, such as to monomers for various polymers. These polymers may be combined with the nanocellulose to form completely renewable composites.

公开(公告)号：US20230417740A1

公开(公告)日：2023-12-28

申请号：US18319832

申请日：2023-05-18

申请人： Wake Forest University Health Sciences

发明人： Aleksander Skardal ,  Shay Soker

IPC分类号： G01N33/50 ,  C08H8/00 ,  C08B37/00 ,  C08H7/00 ,  B33Y70/00 ,  B29C64/106 ,  B01L3/00 ,  C12N5/071

CPC分类号： G01N33/5082 ,  C08H8/00 ,  C08B37/0057 ,  C08H6/00 ,  B33Y10/00 ,  B29C64/106 ,  B01L3/5027 ,  C12N5/0671 ,  G01N33/5014 ,  B33Y70/00

摘要： An extrudable hydrogel composition useful for making a three-dimensional organ construct includes a cross-linkable prepolymer, a post-deposition crosslinking group, optionally, an initiator that catalyzes the reaction between the prepolymer and said the crosslinking group; live cells (e.g., plant, animal, or microbial cells), optionally at least one growth factor, and optionally water to balance. Methods of using the same and products so made are also described.

公开(公告)号：US11802169B2

公开(公告)日：2023-10-31

申请号：US16960895

申请日：2019-08-16

申请人： INSTITUTE OF CHEMICAL INDUSTRY OF FOREST PRODUCTS, CAF

发明人： Kui Wang ,  Jianchun Jiang ,  Yanyan Liu ,  Junming Xu ,  Min Wei ,  Linshan Wei ,  Ruizhen Wang

IPC分类号： C08B37/00

CPC分类号： C08B37/0057

摘要： The invention proposes a method of separating hemicellulose through efficient pretreatment of fibrous biomass materials. Fibrous biomass materials are first pretreated by the slurry method: the fibrous biomass materials are milled through ball mills and sieved to obtain fibrous biomass material powder, and the powder is mixed with water at room temperature to obtain slurry premixed solution of the fibrous biomass material powder. Through regulation and control of the reaction temperature, the time and the water amount, efficient hydrothermal removal of hemicellulose from the fibrous biomass material powder is realized. After the mixed solution is filtered, the filtrate is subject to gradient sedimentation to separate hemicellulose with low dispersity, and the sediment is then dried before storage. After the filter residue is mixed with polar aprotic solvent and water, and heated and stirred in a pressurized reactor, high-purity cellulose is obtained through filtering and separation.

公开(公告)号：US11649296B2

公开(公告)日：2023-05-16

申请号：US17880551

申请日：2022-08-03

申请人： Renmatix, Inc.

发明人： Ewellyn A. Capanema ,  Mikhail Y. Balakshin ,  Patrick David Fitzgibbon ,  Matyas Kosa ,  Todd Michael McLarty ,  Charles Sebastian Sanderson

IPC分类号： C09J161/00 ,  C08B15/08 ,  C08B37/00 ,  C08H7/00 ,  C08L97/00 ,  C08L1/02 ,  C08B15/00 ,  C09J101/02 ,  C09J161/06 ,  C09J175/04 ,  C08B15/02 ,  C07G1/00 ,  C08B11/18 ,  C08B15/06 ,  C08L97/02 ,  C09J11/06 ,  C09J201/00 ,  G01N23/20

CPC分类号： C08B15/08 ,  C07G1/00 ,  C08B11/18 ,  C08B15/00 ,  C08B15/02 ,  C08B15/06 ,  C08B37/0057 ,  C08H6/00 ,  C08L1/02 ,  C08L97/005 ,  C08L97/02 ,  C09J101/02 ,  C09J161/06 ,  C09J175/04 ,  C09J11/06 ,  C09J201/00 ,  G01N23/20 ,  C09J161/06 ,  C08L1/02

摘要： Cellulose-containing compositions and method of making same are disclosed. The compositions comprise a cellulose product comprising a type-I cellulose, a type-II cellulose, amorphous cellulose, or a combination thereof. Further, methods are disclosed for making these compositions and for further hydrolyzing these compositions. Additionally, uses for the cellulose-containing compositions are disclosed.

公开(公告)号：US20190218242A1

公开(公告)日：2019-07-18

申请号：US16363781

申请日：2019-03-25

申请人： RENMATIX, INC.

发明人： Patrick David Fitzgibbon ,  Thomas Arthur Kindler ,  Todd Michael McLarty ,  Charles Sebastian Sanderson ,  Michael L. Smith

IPC分类号： C07G1/00 ,  C08B37/00 ,  C08H8/00 ,  C08H7/00

CPC分类号： C07G1/00 ,  C08B37/0057 ,  C08H6/00 ,  C08H8/00

摘要： Provided is a method of coalescing a substance comprising providing a first mixture comprising a substance, agitating at least a portion of the first mixture under turbulent conditions for a first time period, thereby causing particles comprising and substance to collide and form into larger particles.

公开(公告)号：US20180201870A1

公开(公告)日：2018-07-19

申请号：US15527688

申请日：2015-12-01

申请人： Council of Scientific and Industrial Research

发明人： Prasanta Kumar Rout ,  Ashween Deepak Nannaware ,  Om Prakash ,  Ram Rajasekharan

IPC分类号： C11B1/10 ,  C11B7/00 ,  C08B37/00 ,  C08H8/00 ,  B01D11/02

CPC分类号： C11B1/10 ,  B01D11/0284 ,  B01D11/0288 ,  C08B37/0003 ,  C08B37/0057 ,  C08H8/00 ,  C11B7/0058

摘要： Agricultural residues (biomasses) have come-up as potential valuable renewable resources for transformation into many bio-products. To achieve this goal, the isolation of major biopolymers in their purest form through an economical process is demanded for synthesis of the target fine chemicals without impurities. However, the difficulty of fractionating the biomass into cellulose, hemicellulose and lignin by a simple method has greatly limited their isolation from agricultural residues. Also, the lipids and waxes present on the surface of the agricultural residues protect it from external chemical and microbial agents. To overcome this issue, the lipids and waxes have been isolated from the biomass through two step organic solvents extraction. Thereafter lignin, hemicellulose and cellulose are isolated successively from the de-waxed biomass.

公开(公告)号：US10005936B2

公开(公告)日：2018-06-26

申请号：US14646445

申请日：2013-11-21

申请人： Nanyang Technological University

发明人： W. J. Terry Steele ,  Vladislav Papper ,  Robert S. Marks

IPC分类号： C09J167/04 ,  C09J105/04 ,  A61N5/06 ,  C09J189/00 ,  C08K9/04 ,  C08K9/02 ,  A61K31/715 ,  A61K31/734 ,  C08G63/685 ,  A61L24/00 ,  A61L24/04 ,  C09J105/10 ,  C08B11/08 ,  C08B15/00 ,  C08B31/00 ,  C08B33/00 ,  C08B35/00 ,  C08B37/00 ,  C08B37/02 ,  C08B37/08 ,  C08H1/06 ,  C09J101/08 ,  C09J101/28 ,  C09J103/04 ,  C09J103/14 ,  C09J105/00 ,  C09J105/02 ,  C09J105/08 ,  C09J189/06 ,  A61K45/06 ,  A61K33/00 ,  A61K9/00 ,  C09J201/02 ,  C08J5/12

CPC分类号： C09J167/04 ,  A61K9/0014 ,  A61K9/0024 ,  A61K31/715 ,  A61K31/734 ,  A61K33/00 ,  A61K45/06 ,  A61L24/001 ,  A61L24/0031 ,  A61L24/046 ,  A61L2430/34 ,  A61N5/062 ,  C08B11/08 ,  C08B15/00 ,  C08B31/00 ,  C08B33/00 ,  C08B35/00 ,  C08B37/00 ,  C08B37/0021 ,  C08B37/003 ,  C08B37/0057 ,  C08B37/0072 ,  C08B37/0075 ,  C08B37/0084 ,  C08G63/6852 ,  C08H1/06 ,  C08J5/128 ,  C08J2300/16 ,  C08J2367/04 ,  C08J2389/00 ,  C08J2400/106 ,  C08K9/02 ,  C08K9/04 ,  C08L2205/16 ,  C09J101/08 ,  C09J101/284 ,  C09J103/04 ,  C09J103/14 ,  C09J105/00 ,  C09J105/02 ,  C09J105/04 ,  C09J105/08 ,  C09J105/10 ,  C09J189/00 ,  C09J189/06 ,  C09J201/025 ,  C08L79/00 ,  A61K2300/00

摘要： A novel diazirine-based biocompatible polymer that can be used as on-demand or tunable bioadhesive and applied across various clinically important surfaces. The biocompatible polymer comprises a single strand of repeating units and up to 5,000 photoreactive diazirine groups covalently attached to it. A bioadhesive composition comprises the polymer of the present invention and suitable solvents, surfactants, stabilizers, fillers and other additives. The composition may additionally contain metallic particles of size less than 50 micron made of rare earth elements and has UV or NIR transparency less than 1 optical density unit per 1 centimeter. The poly-diazirine surface grafted thin films can be used for minimally invasive surgeries.

公开(公告)号：US20170327523A1

公开(公告)日：2017-11-16

申请号：US15525604

申请日：2014-11-12

申请人： RENMATIX, INC.

发明人： Patrick David Fitzgibbon ,  Thomas Arthur Kindler ,  Todd Michael McLarty ,  Charles Sebastian Sanderson ,  Michael L. Smith

IPC分类号： C07G1/00 ,  C08B37/00

CPC分类号： C07G1/00 ,  C08B37/0057 ,  C08H6/00 ,  C08H8/00

摘要： Provided is a method of coalescing a substance comprising providing a first mixture comprising a substance, agitating at least a portion of the first mixture under turbulent conditions for a first time period, thereby causing particles comprising and substance to collide and form into larger particles.