公开(公告)号：US20240059443A1

公开(公告)日：2024-02-22

申请号：US18270932

申请日：2022-01-11

申请人： PHARMA INTEGRATION S.R.L.

发明人： Claudio BECHINI

IPC分类号： B65B43/46 ,  B65B31/00 ,  B65B3/00

CPC分类号： B65B43/46 ,  B65B31/00 ,  B65B3/003

摘要： A device (1) for moving a group of containers (A) for pharmaceutical or biotechnological use, between chambers (11, 12) with a controlled atmosphere comprising a support structure (7), supports (2) configured to accommodate containers (A) with an exposed part (B), a guide (3) for guiding the supports (2), rotationally coupled to the support structure (7), first rotating means (4) of the guide (3) and movement means (5) of the supports along the guide (3). The guide (3) rotates to locate the exposed parts (B) of the containers (A) in one of the chambers (11, 12) and the movement means (5) vary the distances (D) between the supports (2), preferably by means of a main body (51) which is rotationally coupled to the guide (3) and which comprises an external surface (52) on which tracks are formed (53, 54, 55, 56, 57, 58, 59, 60). Also described are an apparatus (100) and a method for producing pharmaceutical or biotechnological articles.

公开(公告)号：US11878829B2

公开(公告)日：2024-01-23

申请号：US18063980

申请日：2022-12-09

申请人： NEW SPS POD, LLC

发明人： Thomas M. McLenithan ,  Andrzej Kepinski ,  John Paselsky ,  Jeff Williams ,  Richard McKenzie ,  Richard Bishop

IPC分类号： B65B3/02 ,  B65B9/04 ,  B65B31/00 ,  B65B39/14 ,  B65B41/12 ,  B65B43/52 ,  B65B47/02 ,  B65B51/00 ,  B65B61/06 ,  B65D65/46 ,  C11D17/04

CPC分类号： B65B9/042 ,  B65B3/022 ,  B65B31/00 ,  B65B39/14 ,  B65B41/12 ,  B65B43/52 ,  B65B47/02 ,  B65B51/00 ,  B65B61/06 ,  B65D65/46 ,  C11D17/042 ,  C11D17/045

摘要： A packaging machine is provided for producing single and multiple compartment film wrapped pouches. Multiple linear motors allow aspects of the forming, filling, cutting and discharging to run at different speeds. The pouches are formed, filled and discharged from platens that are secured to movers that proceed through the packaging process by following magnetic fields created by independently controlled linear motors. Overall, cycle time is decreased as a result of speeding up parts of the process, including the platen return process, possible because there is no mechanical connection and not a single conveyor moving the platens while the other parts of the process may be simultaneously slowed down or even temporarily stopped. Changeover of platens, to accommodate different products, such as single compartment pouch to multiple compartment pouches, is also simplified because platens are simply connected to the movers and are thus easily removed and replaced.

公开(公告)号：US11731822B2

公开(公告)日：2023-08-22

申请号：US17470935

申请日：2021-09-09

申请人： A. RAYMOND ET CIE

发明人： Gaëtan Rey

IPC分类号： A61B50/33 ,  B65D77/00 ,  B65B5/06 ,  B65B7/28 ,  B65B31/00 ,  B65D25/10 ,  B65D81/20 ,  A61B50/00 ,  A61B50/30

CPC分类号： B65D77/003 ,  A61B50/33 ,  B65B5/068 ,  B65B7/2842 ,  B65B31/00 ,  B65D25/108 ,  B65D81/2015 ,  A61B2050/006 ,  A61B2050/3008 ,  A61B2050/314

摘要： A packaging system for medical containers having a main opening, comprising: a vessel having a shoulder; a tray provided with cavities that is intended for receiving a medical container and rests on the shoulder; a plurality of caps that close the main opening; and a lid that seals the vessel. A method for packaging medical containers, comprises the following steps: providing a vessel; arranging a tray on the shoulder of the vessel; arranging medical containers in the cavities; arranging a cap on the medical containers so as to close the main opening thereof; sealing a lid on an upper edge of the peripheral wall of the vessel; and placing the vessel in at least one sealed bag.

公开(公告)号：US10077124B2

公开(公告)日：2018-09-18

申请号：US14667179

申请日：2015-03-24

申请人： TOYO SEIKAN GROUP HOLDINGS, LTD.

发明人： Ryo Suenaga ,  Satoshi Tanaka ,  Kyohei Ota

IPC分类号： B01D19/00 ,  B65B9/04 ,  B01L3/00 ,  C12M1/00 ,  C12M1/34 ,  B65B31/00

CPC分类号： B65B9/042 ,  B01L3/502723 ,  B01L3/505 ,  B01L2200/0684 ,  B01L2300/0654 ,  B01L2400/0481 ,  B65B31/00 ,  C12M23/14 ,  C12M41/36

摘要： A method for removing bubbles from an observation area includes pressing, with a pressing member, a part of an upper surface of the container that is positioned above the observation area, and moving the pressing member so as to push the bubbles outside the observation area.

公开(公告)号：US10053244B2

公开(公告)日：2018-08-21

申请号：US15049453

申请日：2016-02-22

申请人： ROLLS-ROYCE plc

发明人： Daniel Clark

IPC分类号： B65B1/04 ,  B22F3/00 ,  B22F3/15 ,  B65B31/00

CPC分类号： B65B1/04 ,  B22F3/003 ,  B22F3/004 ,  B22F3/15 ,  B65B31/00

摘要： The present invention provides a pipe for transferring powder material from a reservoir to a container e.g. prior to hot isostatic pressing. The pipe comprises a continuous outer wall and a concentric continuous inner wall enclosed within and spaced from the outer wall. The spacing between the inner and outer walls defines a flow channel extending from an inlet to an outlet. The radial cross sectional area of the outlet is greater than the cross sectional area of the inlet.

公开(公告)号：US09950820B2

公开(公告)日：2018-04-24

申请号：US14889017

申请日：2015-01-22

申请人： YUSHIN CO., LTD.

发明人： Katsunori Futase

IPC分类号： B65B31/00 ,  B65B9/08 ,  B65B7/02 ,  B65D75/58 ,  B65B51/10 ,  B65B31/04 ,  B65B55/00 ,  B65B61/18 ,  B65B9/06 ,  B65B51/30

CPC分类号： B65B31/00 ,  B65B7/02 ,  B65B9/06 ,  B65B9/08 ,  B65B31/045 ,  B65B51/10 ,  B65B51/306 ,  B65B55/00 ,  B65B61/186 ,  B65D75/5883

摘要： A method for filling and packing a gas and a liquid material by filling the gas in an amount corresponding to 2-40 vol % of the volume of the liquid material together with the liquid material into a package bag composed of plastic films through an unsealed opening portion thereof and then sealing the unsealed opening portion by heat sealing, characterized in that the gas is previously dispersed and incorporated in form of microbubbles having a diameter of not more than 50 μm in to the liquid material and filled into in the package bag at a state of microbubble-containing liquid material, or the gas is filled while generating as microbubbles having a diameter of not more than 50 μm in the liquid material previously supplied to the package bag.

公开(公告)号：US20180043020A1

公开(公告)日：2018-02-15

申请号：US15793976

申请日：2017-10-25

申请人： Coherus Biosciences, Inc.

发明人： John Ogez ,  Jun Liu ,  Wenchang Ji ,  Patrick Daniel Begley ,  Isaias Prado ,  Mark Manning

IPC分类号： A61K39/395 ,  B65B7/28 ,  B65B3/00 ,  B65B31/00 ,  A61K9/08 ,  C07K16/24

CPC分类号： A61K39/39591 ,  A61K9/0019 ,  A61K9/08 ,  A61K9/19 ,  A61K47/183 ,  B65B3/003 ,  B65B3/006 ,  B65B7/28 ,  B65B7/2821 ,  B65B31/00 ,  B65B31/027 ,  C07K16/241 ,  C07K2317/21 ,  C07K2317/76

摘要： The present invention is directed to methods for reducing immunogenicity of a drug product, utilizing filling a container wherein the filled container has no headspace. The present invention is further directed to methods for stabilizing an aqueous drug substance solution by filling a container with the aqueous drug substance solution wherein the filled container has no headspace. The present invention is further directed to formulations of drug substances with reduced immunogenicity.

公开(公告)号：US20180000135A1

公开(公告)日：2018-01-04

申请号：US15707923

申请日：2017-09-18

申请人： Thomas D. Gillette

发明人： Thomas D. Gillette

IPC分类号： A23L3/00 ,  B65B55/14 ,  B65B55/06 ,  B65B55/02 ,  B65B31/00 ,  B65B25/00 ,  A23L3/358 ,  B65B55/18 ,  A23L3/02

CPC分类号： A23L3/00 ,  A23L3/02 ,  A23L3/358 ,  B65B25/001 ,  B65B31/00 ,  B65B55/02 ,  B65B55/06 ,  B65B55/14 ,  B65B55/18

摘要： Systems and methods for packaging food products, such as fruits, vegetables, and meats. Specifically, the described methods relate to systems and methods for packaging food products in a manner that increases the products' shelf life. Generally, the methods begin by providing a food product. In some cases, debris is removed from the food product. To kill bacteria and other microbes on the food product, the food product is optionally washed in ozonated water. To deactivate enzymes within the food product, the food product is heated, though not necessarily cooked or blanched. The food product is then typically sealed in a barrier package containing between about 1 percent and about 50 percent oxygen, by volume. In some cases, the sealed package is then heated to between about 165 and about 285 degrees Fahrenheit to kill microbes in the sealed package. Other implementations are also described.

公开(公告)号：US20170320617A1

公开(公告)日：2017-11-09

申请号：US15147184

申请日：2016-05-05

申请人： Luis Burgos Agudo

发明人： Luis Burgos Agudo

IPC分类号： B65D5/44 ,  B65D77/22 ,  B65D75/58 ,  B65B61/20 ,  B65B51/22 ,  B65B31/00 ,  B65B7/20 ,  B65D83/06 ,  B65B1/02

CPC分类号： B65D5/443 ,  B31B50/84 ,  B65B1/02 ,  B65B7/20 ,  B65B31/00 ,  B65B31/047 ,  B65B51/225 ,  B65B61/20 ,  B65D5/721 ,  B65D5/746 ,  B65D75/5877 ,  B65D77/225 ,  B65D81/2076 ,  B65D83/06

摘要： A laminated package for solid products in powder or grain form, includes a set of stiffening notches, a dispensing mouth with a seal, valves for loading inert gas, in which the lateral folds of the upper face are folded inwards under the front and rear flaps, and the lateral folds of the lower face are folded outward and folded and stuck on the lower face over the front and rear flaps, and a method for forming the package.

公开(公告)号：US20170283098A1

公开(公告)日：2017-10-05

申请号：US15630580

申请日：2017-06-22

申请人： Frito-Lay North America, Inc.

发明人： Eduard EDWARDS ,  Chad Arthur HUEBNER

IPC分类号： B65B1/22 ,  B65B51/30 ,  B65B65/02 ,  B65B9/207 ,  B65B31/00

CPC分类号： B65B1/22 ,  B65B9/2007 ,  B65B9/2049 ,  B65B9/207 ,  B65B31/00 ,  B65B51/30 ,  B65B51/306 ,  B65B65/02

摘要： A method and apparatus for settling a product in a package made on a form, fill and seal machine. In one aspect the invention comprises the steps: providing a package material on a product conduit of a form, fill and seal machine; forming a first end seal on the package material to form a partially formed package; filling the partially formed package with product; and settling the product in the partially formed package while continuously conveying the package material along the product conduit. In a second aspect, the invention comprises a product settler comprising a first object positioned to cause an impact against a package material. The impact agitates the package material and settles a product from an unsettled height to a settled height while the package material is continuously conveyed.