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公开(公告)号:US11952155B2
公开(公告)日:2024-04-09
申请号:US17296770
申请日:2019-11-25
CPC分类号: B65B3/003 , A61J1/10 , A61J1/1475 , A61J1/2024 , A61J1/2093 , B65B3/022 , B65B29/10
摘要: A method of manufacturing a flexible container housing a drug substance is disclosed that includes forming a first compartment from a flexible sheet-like material, filling a liquid into the first compartment, sealing the first compartment, forming a second compartment from the flexible sheet-like material, filling a dry drug formulation into the second compartment, and sealing the second compartment. The method further involves lyophilizing the drug formulation inside a tubular cartridge, filling the second compartment by introducing the tubular cartridge through an opening of the second compartment such that an open end of the tubular cartridge is positioned distant from the opening of the second compartment, providing the drug formulation from the open end of the tubular cartridge into the second compartment, and withdrawing the tubular cartridge from the second compartment. The first and second compartments are separated by a frangible seal which opens when the first compartment is compressed.
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公开(公告)号:US20180237175A1
公开(公告)日:2018-08-23
申请号:US15961391
申请日:2018-04-24
发明人: R. Charles Murray
CPC分类号: B65B9/2056 , B65B9/2014 , B65B29/10 , B65B2220/22 , B65B2230/02 , B65D81/3266
摘要: A machine and a method for forming a two-compartment pouch having a lower compartment and an upper compartment The method includes the steps of drawing a film over a pair of fill tubes; sealing side edges of the film to form a sleeve; forming a bottom seal on the sleeve; pulling the sleeve downwardly; filling a bottom portion of the pouch using one of the fill tubes; forming a second seal over the filled bottom portion; filling an upper portion of the pouch using the other fill tube; and sealing the upper portion.
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公开(公告)号:US10011399B1
公开(公告)日:2018-07-03
申请号:US14712929
申请日:2015-05-15
申请人: Loren S. Adell
发明人: Loren S. Adell
IPC分类号: B65D35/24 , B05C17/005 , B65B3/04 , B65B51/10 , B65B43/02 , B65D17/50 , B65D77/06 , B65D35/22 , B65D77/08 , B29C65/72 , B29C65/76 , A61K6/00
CPC分类号: B65D35/242 , A61K6/00 , B05C17/00563 , B29C65/72 , B29C65/76 , B65B3/04 , B65B9/023 , B65B29/10 , B65B51/10 , B65B61/20 , B65D35/22 , B65D35/24 , B65D75/5811 , B65D77/06 , B65D77/08 , B65D81/3266
摘要: A hermetically sealed enclosure for use in fabricating a polymeric dental article. Monomers are mixed within the enclosure by squeezing a first burst pouch to break a first burst seal between it and a second burst pouch and manipulating the enclosure by hand to initiate a polymerization reaction while the enclosure remains hermetically sealed. A second burst seal between the second burst pouch and a dispensing funnel chamber is broken by further squeezing which forces the mixture into the dispensing funnel chamber. The mixture is dispensed from an outlet of the dispensing funnel chamber by further squeezing after a tear-off strip closing the outlet has been torn off.
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公开(公告)号:US09981761B2
公开(公告)日:2018-05-29
申请号:US14862785
申请日:2015-09-23
发明人: R. Charles Murray
CPC分类号: B65B9/2056 , B65B9/2014 , B65B29/10 , B65B2220/22 , B65B2230/02 , B65D81/3266
摘要: A machine and a method for forming a two-compartment pouch having a lower compartment and an upper compartment The method includes the steps of drawing a film over a pair of fill tubes; sealing side edges of the film to form a sleeve; forming a bottom seal on the sleeve; pulling the sleeve downwardly; filling a bottom portion of the pouch using one of the fill tubes; forming a second seal over the filled bottom portion; filling an upper portion of the pouch using the other fill tube; and sealing the upper portion.
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公开(公告)号:US09856045B2
公开(公告)日:2018-01-02
申请号:US14475275
申请日:2014-09-02
发明人: Nicholas Wu
IPC分类号: B65B55/02 , A61L2/08 , B65B3/02 , B65B29/10 , B65B55/08 , B65B55/10 , B65B3/00 , B65B31/02 , B65B57/04 , B65B57/06 , B65B57/08 , B65B57/18
CPC分类号: B65B55/027 , A61L2/087 , B65B3/003 , B65B3/02 , B65B29/10 , B65B31/024 , B65B55/08 , B65B55/10 , B65B57/04 , B65B57/06 , B65B57/08 , B65B57/18 , B65B2220/14 , B65B2230/02
摘要: A flexible container, system and method of manufacture can include an in-line system that allows flexible containers of varying sizes to be manufactured in a single relatively high speed and efficient production line and in a single clean room through the use of transport and exchange equipment configured to adeptly handle flexible containers throughout the process.
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公开(公告)号:US20170015052A1
公开(公告)日:2017-01-19
申请号:US15113923
申请日:2015-03-25
发明人: Huide D. Zhu , Lirong Zhou , Michael C. Cocca , Andrew R. Kneisel , Daniel P. Sophiea , Matthew B. Feldpausch , Gary L. Jialanella
CPC分类号: B29C65/4805 , B05B15/20 , B29L2031/10 , B29L2031/30 , B60J1/006 , B60J10/34 , B65B29/10 , B65D35/22 , B65D81/3244 , B65D81/3261 , B65D81/3272 , E21D20/026
摘要: A two-component reactive dispensing system that is pliable is comprised of an outer sausage tubular member having therein an inner sausage tubular member in which the inner tubular member is bonded to the inner surface of the outer sausage tubular member longitudinally along a portion of the outer surface of the inner tubular sausage member. The compartments formed by the inner and outer tubular sausage members are filled with materials that are reactive with each other and the ends are sealed by gathering the ends and sealed using, for example wire wrap around clips.
摘要翻译: 柔软的双组分反应性分配系统由外肠道管状构件组成,其中具有内部香肠管状构件,其中内部管状构件沿着外部肠衣的一部分纵向地连接到外部香肠管状构件的内表面 内部管状肠衣的表面。 由内外管状构件形成的隔室用彼此反应的材料填充,并且端部通过收集端部而被密封,并且通过例如围绕夹子的缠绕线进行密封。
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公开(公告)号:US20160270602A1
公开(公告)日:2016-09-22
申请号:US15166501
申请日:2016-05-27
发明人: Theodore Casey
摘要: A container system for separately storing and mixing two or more substances. The container system comprises a mixing container having a main container that stores one or more first substances. The main container has a first upper opening. The container system also includes a storage repository coupled to main container, and which stores one or more second substances. The storage repository includes a lip defining a second upper opening, which has an outside diameter smaller than the diameter of the first upper opening. A method and an assembly system for coupling components of a container system. The assembly system may include a conveyor belt and an assembly apparatus with a motor driving a pulley wheel, and a continuous belt rotationally driven by the pulley wheel, the continuous belt rotationally disposed on at least one locking wheel.
摘要翻译: 用于分别存储和混合两种或多种物质的容器系统。 容器系统包括具有存储一种或多种第一物质的主容器的混合容器。 主容器具有第一上开口。 容器系统还包括联接到主容器并且存储一个或多个第二物质的储存库。 存储库包括限定第二上部开口的唇缘,该第二上部开口的外径小于第一上部开口的直径。 一种用于联接容器系统的部件的方法和装配系统。 组装系统可以包括传送带和具有驱动皮带轮的马达的组装装置,以及由滑轮旋转地驱动的连续皮带,连续的带旋转地设置在至少一个锁定轮上。
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公开(公告)号:US20160158720A1
公开(公告)日:2016-06-09
申请号:US15042975
申请日:2016-02-12
申请人: Todd Schroeter
发明人: Todd Schroeter
CPC分类号: B01J7/02 , A61L2/20 , A61L9/015 , A61L2202/11 , B01J8/008 , B01J2208/00814 , B65B7/02 , B65B29/10 , C01B11/024 , C02F1/685 , C02F1/76
摘要: A device for facilitating a chemical reaction while submerged in a liquid catalyst includes an upper member, a lower member, and a dissolvable member disposed between and ultimately enclosed by said upper and lower members such that upper and lower chambers are formed having substantially equal volumes. The upper chamber may receive a dry sodium chlorite and the lower chamber may receive a dry acid mixture. In order to keep the device submerged in the liquid catalyst, an inert ballast may also be added to the upper and/or lower chamber, such as glass shards.
摘要翻译: 用于在浸没在液体催化剂中时促进化学反应的装置包括上部构件,下部构件和设置在所述上部和下部构件之间并最终被所述上部和下部构件包围的可溶解构件,使得形成具有基本相等体积的上部和下部腔室。 上部室可以接收干燥的亚氯酸钠,并且下部室可以接收干酸混合物。 为了将装置浸没在液体催化剂中,还可以向上部和/或下部室(例如玻璃碎片)中添加惰性镇流器。
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公开(公告)号:US20150013276A1
公开(公告)日:2015-01-15
申请号:US14272500
申请日:2014-05-07
申请人: ARTE CORPORATION
发明人: Kiyoshi OKAJIMA , Seiji SHIMAZAKI
CPC分类号: A61M5/2448 , A61J1/20 , A61L2/07 , A61M5/001 , A61M5/002 , A61M5/008 , A61M5/1782 , A61M5/284 , A61M2005/3114 , A61M2207/00 , B65B3/003 , B65B3/027 , B65B7/161 , B65B7/2821 , B65B29/10 , B65B31/027 , B65B63/08 , B65B2220/14 , B65B2230/02
摘要: A manufacturing method of two-chamber type combined container-syringe including: a vacuum plugging process (S2) of eliminating air bubbles from the dissolving solution of the dissolving solution-filled cartridge and sealing the dissolving solution with a middle stopper after the dissolving solution filling process (S1); a vacuum plugging process (S2) has a first cooling processing (S21) of cooling the inside of a vacuum plugging equipment in which a dissolving solution-filled cartridge is disposed to a cooling temperature that does not freeze the dissolving solution, a first decompression processing (S23) of decreasing a pressure inside the vacuum plugging equipment while the vacuum plugging equipment maintains the cooling temperature after the first cooling processing (S21), and a middle stopper pushing processing (S24) of pushing the middle stopper downward and bringing the middle stopper into contact with the dissolving solution after the first decompression processing (S23). The dissolving solution can be easily filled in a bubble-free state in the two-chamber type combined container-syringe.
摘要翻译: 一种双室型组合容器注射器的制造方法,包括:从溶解液填充药筒的溶解液中除去气泡的真空堵塞工序(S2),在溶解液填充后用中间塞子密封溶解液 过程(S1); 真空堵塞处理(S2)具有冷却处理(S21),其中将填充有溶解液的筒体的真空堵塞设备的内部冷却至不冷冻溶解溶液的冷却温度,第一减压处理 (S23),在真空堵塞设备保持第一冷却处理之后的冷却温度(S21)的同时减小真空堵塞设备内部的压力的中间止动器推动处理(S24),并且使中间止动器 在第一减压处理后与溶解溶液接触(S23)。 溶解液可以容易地在双室型组合容器注射器中以无气泡状态填充。
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公开(公告)号:US08567437B2
公开(公告)日:2013-10-29
申请号:US12940342
申请日:2010-11-05
IPC分类号: F16K11/16
CPC分类号: E21D20/026 , B65B29/10 , Y10T137/0318 , Y10T137/8766 , Y10T137/87684 , Y10T137/87692
摘要: Provided is a system and method for producing resin cartridges that can be used in mine roof bolt applications. The system and method can be used to produce resin cartridges that contain a first portion that includes a resin and a catalyst that cure at a first speed when mixed together and a second portion that includes a resin and a catalyst that cure at a second speed when mixed together. The system can include a base material supply source, a plurality of branch lines, at least one altering material supply line in fluid communication with at least one branch line, a valve arrangement, a product line, and a packaging machine.
摘要翻译: 提供了可用于矿山屋顶螺栓应用中的用于生产树脂盒的系统和方法。 该系统和方法可以用于生产含有第一部分的树脂盒,该第一部分包括树脂和在混合时以一速固化的催化剂,以及包含树脂的第二部分和以第二速度固化的催化剂, 混在一起 该系统可以包括基材供应源,多个分支管线,至少一个与至少一条分支管线流体连通的改变材料供应管线,阀门装置,产品线和包装机器。
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