公开(公告)号：US20160267731A1

公开(公告)日：2016-09-15

申请号：US14784613

申请日：2013-04-16

Applicant: WISCONSIN ALUMNI RESEARCH FOUNDATION

Inventor： Jannah A. Stanley ,  Ashley Chapman ,  Matthew Joyce

IPC: G07C9/00

CPC classification number: G07C9/00134 ,  B01L3/0255 ,  B01L3/0262 ,  B01L3/0293 ,  B01L3/50273 ,  B01L3/563 ,  B01L2200/16 ,  B01L2300/047 ,  B01L2300/0672 ,  B01L2300/0816 ,  B01L2400/024 ,  B01L2400/0406 ,  B01L2400/0481 ,  B01L2400/0683 ,  G07C9/00166 ,  G07C2209/08

Abstract: Embodiments are directed to providing access without determining an identity of a requester. A fixture may receive a rule pertaining to access to a floor of a building. The fixture may receive a request to access the floor of the building. The fixture may grant access to the floor based on a determination that the rule indicates that access to the floor should be granted.

Abstract translation: 实施例旨在提供访问而不确定请求者的身份。 固定装置可以接收关于访问建筑物楼层的规则。 固定装置可以接收到访问建筑物楼层的请求。 基于确定规则表明应该授予对楼层的访问，该固定装置可以授予访问权限。

公开(公告)号：US08287744B2

公开(公告)日：2012-10-16

申请号：US12775452

申请日：2010-05-06

Applicant: Thomas Hantschel ,  David K. Fork ,  Eugene M. Chow ,  Dirk De Bruyker ,  Michel A. Rosa

Inventor： Thomas Hantschel ,  David K. Fork ,  Eugene M. Chow ,  Dirk De Bruyker ,  Michel A. Rosa

IPC: B44C1/22 ,  B32B38/10 ,  C23C14/34

CPC classification number: G01N35/1074 ,  B01J2219/00387 ,  B01L3/0244 ,  B01L3/0255 ,  B01L3/502715 ,  B01L2300/0819 ,  B01L2400/025 ,  B01L2400/0406 ,  B41J2/14314 ,  B41J2/16 ,  B41J2/1628 ,  B41J2/1629 ,  B41J2/1631 ,  B41J2/1632 ,  B41J2/1639 ,  B41J2/1643 ,  C40B60/14 ,  G01N35/1009 ,  G01N2035/00237 ,  G01N2035/1037 ,  G03F7/0002 ,  Y10T436/2575

Abstract: Fluidic conduits, which can be used in microarraying systems, dip pen nanolithography systems, fluidic circuits, and microfluidic systems, are disclosed that use channel spring probes that include at least one capillary channel. Formed from spring beams (e.g., stressy metal beams) that curve away from the substrate when released, channels can either be integrated into the spring beams or formed on the spring beams. Capillary forces produced by the narrow channels allow liquid to be gathered, held, and dispensed by the channel spring probes. Because the channel spring beams can be produced using conventional semiconductor processes, significant design flexibility and cost efficiencies can be achieved.

公开(公告)号：US08241508B2

公开(公告)日：2012-08-14

申请号：US11463940

申请日：2006-08-11

Applicant: Brian R D'Urso ,  John T Simpson

Inventor： Brian R D'Urso ,  John T Simpson

IPC: C25F3/00

CPC classification number: H01J9/025 ,  B01L3/0244 ,  B01L3/0255 ,  B01L2200/12 ,  B01L2300/0819 ,  B05D5/083 ,  B82Y30/00 ,  C03C4/00 ,  C03C15/00 ,  C03C2204/08 ,  G01N33/54393 ,  H01J1/3044 ,  Y10T428/24149 ,  Y10T428/24479 ,  Y10T428/3154 ,  Y10T428/31678

Abstract: A method of making a composite material having sharp surface features includes the steps of: making a composite body comprised of a recessive phase and a protrusive phase, the recessive phase having a higher susceptibility to a preselected etchant than the protrusive phase; and treating a surface of the composite body with the preselected etchant so that the protrusive phase protrudes from the surface to form a sharp surface feature, and the recessive phase defines a recessed surface area between the surface features.

Abstract translation: 制备具有尖锐表面特征的复合材料的方法包括以下步骤：制备由隐性相和突出相组成的复合体，所述隐性相对预选蚀刻剂的敏感性高于突出相; 以及用预选的蚀刻剂处理复合体的表面，使得突出相从表面突出以形成锋利的表面特征，并且隐性相限定了表面特征之间的凹陷表面积。

公开(公告)号：US08147665B2

公开(公告)日：2012-04-03

申请号：US10578318

申请日：2004-11-15

Applicant: Thierry Livache ,  Bruno Corso ,  Thibaut Mercey ,  Nathalie Lassalle

Inventor： Thierry Livache ,  Bruno Corso ,  Thibaut Mercey ,  Nathalie Lassalle

IPC: G01N27/327

CPC classification number: B01L3/0244 ,  B01L3/0255 ,  B01L2300/0645 ,  B01L2400/025

Abstract: The invention relates to a device for receiving a fluid sample, which is designed such as to form an electrode, such as a counter electrode or a working electrode, in an electrochemical cell. The inventive device comprises an end part having at least one cavity which opens to the exterior via an opening and which is equipped with a base. The invention is characterized in that the aforementioned end part comprises a first electrically-insulating hydrophobic zone which is adjacent to the cavity opening and a second electrically-conducting hydrophilic zone which is adjacent to the first zone and which at least partially covers the base of the cavity, such that, when the end part is immersed in the fluid and then removed therefrom, the cavity retains part of the fluid by means of capillary action.

Abstract translation: 本发明涉及一种用于接收流体样品的装置，其被设计成在电化学电池中形成诸如对电极或工作电极之类的电极。 本发明的装置包括具有至少一个空腔的端部，所述至少一个空腔经由开口向外部开口并且具有底座。 本发明的特征在于，上述端部包括与腔开口相邻的第一电绝缘疏水区和邻近第一区的第二导电亲水区，并且至少部分地覆盖第一区的底部 使得当端部浸入流体中然后从其中移出时，空腔通过毛细管作用保持部分流体。

公开(公告)号：US08080221B2

公开(公告)日：2011-12-20

申请号：US12775459

申请日：2010-05-06

Applicant: Thomas Hantschel ,  David K. Fork ,  Eugene M. Chow ,  Dirk De Bruyker ,  Michel A. Rosa

Inventor： Thomas Hantschel ,  David K. Fork ,  Eugene M. Chow ,  Dirk De Bruyker ,  Michel A. Rosa

IPC: B01L3/00

CPC classification number: B01L3/0244 ,  B01J2219/00387 ,  B01L3/0255 ,  B01L3/502715 ,  B01L2300/0819 ,  B01L2400/025 ,  B01L2400/0406 ,  B41J2/14314 ,  B41J2/16 ,  B41J2/1628 ,  B41J2/1629 ,  B41J2/1631 ,  B41J2/1632 ,  B41J2/1639 ,  B41J2/1643 ,  B82Y10/00 ,  B82Y40/00 ,  C40B60/14 ,  G01N35/1009 ,  G01N35/1074 ,  G01N2035/00237 ,  G01N2035/1037 ,  G03F7/0002

Abstract: Fluidic conduits, which can be used in microarraying systems, dip pen nanolithography systems, fluidic circuits, and microfluidic systems, are disclosed that use channel spring probes that include at least one capillary channel. Formed from spring beams (e.g., stressy metal beams) that curve away from the substrate when released, channels can either be integrated into the spring beams or formed on the spring beams. Capillary forces produced by the narrow channels allow liquid to be gathered, held, and dispensed by the channel spring probes. Because the channel spring beams can be produced using conventional semiconductor processes, significant design flexibility and cost efficiencies can be achieved.

Abstract translation: 公开了可用于微阵列系统，浸笔纳米光刻系统，流体回路和微流体系统的流体导管，其使用包括至少一个毛细通道的通道弹簧探针。 由释放时从基板弯曲的弹簧梁（例如，应力金属梁）形成，通道可以集成到弹簧梁中或形成在弹簧梁上。 由窄通道产生的毛细管力允许液体被通道弹簧探针收集，保持和分配。 由于可以使用传统的半导体工艺制造通道弹簧梁，所以可以实现显着的设计灵活性和成本效率。

公开(公告)号：US20100119711A1

公开(公告)日：2010-05-13

申请号：US12613258

申请日：2009-11-05

Applicant: Nathaniel C. CADY ,  Magnus BERGKVIST ,  Alison GRACIAS

Inventor： Nathaniel C. CADY ,  Magnus BERGKVIST ,  Alison GRACIAS

IPC: B05C5/02 ,  G03F7/20

CPC classification number: B01L3/0248 ,  B01L3/0255 ,  B01L2400/0406 ,  B01L2400/0487 ,  B82Y10/00 ,  B82Y40/00 ,  G03F7/0002

Abstract: Polymer-based micro-cantilevers for depositing material onto a surface include, in one embodiment, a body portion, an elongated beam portion sized smaller than and extending from the body portion and having a length greater than about 500 microns. The body portion includes a reservoir and the elongated beam portion having a passageway disposed therein. The passageway has an inlet opening in fluid communication with the reservoir and an outlet opening at a distal end of the elongated beam portion. The passageway comprises a width greater than 10 microns to about 100 microns, and a height of about 25 microns to about 100 microns. Methods for delivering fluid and living cells using the polymer-based micro-cantilevers are also disclosed.

Abstract translation: 在一个实施例中，用于将材料沉积到表面上的聚合物基微悬臂包括主体部分，细长梁部分的尺寸小于并从主体部分延伸并具有大于约500微米的长度。 主体部分包括储存器，并且细长梁部分具有设置在其中的通道。 通道具有与储存器流体连通的入口开口和在细长梁部分的远端处的出口开口。 该通道包括大于10微米至约100微米的宽度，以及约25微米至约100微米的高度。 还公开了使用聚合物基微悬臂梁输送流体和活细胞的方法。

公开(公告)号：US07279135B2

公开(公告)日：2007-10-09

申请号：US10841532

申请日：2004-05-10

Applicant: Chia-Lung Kuo ,  Jr Shiang You ,  Yu Long Huang ,  Ching-Yi Wu

Inventor： Chia-Lung Kuo ,  Jr Shiang You ,  Yu Long Huang ,  Ching-Yi Wu

IPC: B05C1/00 ,  B05C19/06

CPC classification number: B01L3/0255 ,  B01J2219/00387 ,  B01J2219/00585 ,  B01J2219/00596 ,  B01J2219/00605 ,  B01J2219/00621 ,  B01J2219/00659 ,  B01L3/0244 ,  B01L2400/025 ,  C40B60/14 ,  G01N2035/1037

Abstract: A probe for providing micro liquid drops including a main rod, a limiting portion and a probe tip portion is disclosed. At least one guiding flow way and several storing recesses are disposed on the conical outer surface of the probe tip portion. Each storing recess has a volume that is larger than the volume of the guiding flow way. Also, under the gravity and capillarity effect, the output speed is controlled by the number, size and shape of the guiding flow ways and the storing recesses so that each probe structure is strong, the liquid storing capacity is high, its liquid output is stable, it is easier to manufacture the guiding flow ways, and it is easy to clean.

Abstract translation: 公开了一种用于提供包括主杆，限制部分和探针尖端部分的微液滴的探针。 至少一个引导流程和几个存储凹槽设置在探针末端部分的锥形外表面上。 每个储存凹槽具有大于引导流动方式的体积的体积。 此外，在重力和毛细作用效应下，输出速度由引导流路和存储凹槽的数量，大小和形状控制，使得每个探针结构坚固，液体储存能力高，液体输出稳定 ，制造引导流程更容易，易于清洗。

公开(公告)号：US07153699B2

公开(公告)日：2006-12-26

申请号：US10328932

申请日：2002-12-23

Applicant: John Gilbert ,  Jaishree Trikha

Inventor： John Gilbert ,  Jaishree Trikha

IPC: G01N1/10 ,  G01N1/00 ,  G01N1/40 ,  B01L3/02

CPC classification number: C40B50/08 ,  B01L3/0244 ,  B01L3/0248 ,  B01L3/0255 ,  B01L3/06 ,  B01L3/5088 ,  B01L2200/142 ,  B01L2200/143 ,  B01L2200/147 ,  B01L2300/1822 ,  B01L2400/0439 ,  C40B40/10 ,  G01N2035/1037 ,  Y10T436/25 ,  Y10T436/2575

Abstract: A two-pin liquid handling system for crystallizing biomolecules comprises a pair of interacting pins for holding a droplet of liquid therebetween. Each pin includes a tip spaced predetermined distance from the other pin to define a sample acquisition region. The two-pin liquid handling system includes a temperature and humidity control element for controlling the temperature of the sample acquisition region to cause transpiration of water to and from a droplet of biomolecule solution to promote crystallization of the biomolecule.

公开(公告)号：US20060088447A1

公开(公告)日：2006-04-27

申请号：US10515710

申请日：2003-05-27

Applicant: Donald Stimpson ,  Hideji Tajima

Inventor： Donald Stimpson ,  Hideji Tajima

IPC: B01L3/00

CPC classification number: B01L3/50853 ,  B01L3/0244 ,  B01L3/0255 ,  B01L3/563 ,  B01L9/547 ,  B01L2200/12 ,  B01L2300/046 ,  B01L2300/0829 ,  G01N35/1074 ,  G01N2035/1037 ,  Y10T436/110833 ,  Y10T436/15 ,  Y10T436/2575

Abstract: The present invention relates to a samples delivering device, a method of manufacturing a samples applicator, a method of delivering samples, and a base activation device which can handle a plurality of various samples, efficiently and promptly. The invention is constructed so as to have: one or more sets of vessels capable of accommodating fluids containing predetermined samples to be delivered to a base or one or more sets of vessels, a samples supply section having a samples applicator, wherein two or more retention tips capable of retaining a small quantity of fluids by being dipped in each of the fluids accommodated in the vessels are arranged according to the vessels, and a transfer means for relatively moving between the base and the one or more sets of vessels, and the applicator.

Abstract translation: 本发明涉及样品输送装置，制造样品涂布器的方法，输送样品的方法以及能够有效且及时地处理多种样品的基体激活装置。 本发明构造成具有：一组或多组能够容纳含有预定样品的流体的容器以便输送到基底或一组或多组容器，样品供应部分具有样品涂布器，其中两个或更多个保留 根据容器布置能够通过浸入容纳在容器中的每个流体中来保留少量流体的尖端，以及用于在基部和一组或多组容器之间相对移动的转移装置，以及施加器 。

公开(公告)号：US06726883B2

公开(公告)日：2004-04-27

申请号：US10441095

申请日：2003-05-20

Applicant: Seiichiro Ito ,  Mitsuhiro Tachibana ,  Naoki Yokokawa

Inventor： Seiichiro Ito ,  Mitsuhiro Tachibana ,  Naoki Yokokawa

IPC: B41J225

CPC classification number: B01L3/0255 ,  B01J2219/00387 ,  B01J2219/00608 ,  B01J2219/0061 ,  B01J2219/00612 ,  B01J2219/00677 ,  B01L2400/025 ,  B82Y30/00 ,  C40B60/14 ,  Y10T436/2575

Abstract: Identically shaped spots can be formed sequentially and stably by a spotting pin comprising a bar-like plunger 20. Four projections each formed in the shape of a top portion of a quadrangular pyramid are formed on the head of the plunger 20. The apexes 21 of the quadrangular pyramids constituting the projections are located inside a virtual plane extending from the peripheral wall of the plunger.

Abstract translation: 相同形状的斑点可以通过包括棒状柱塞20的斑点针顺序地且稳定地形成。在柱塞20的头部上形成四边形金字塔顶部形状的四个突起。顶点21 构成突起的四角锥体位于从柱塞的周壁延伸的虚拟平面内。