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    Flow passage structure and flow passage structure manufacturing method
    2.
    发明授权
    Flow passage structure and flow passage structure manufacturing method 有权
    流道结构和流道结构制造方法

    公开(公告)号：US09534722B2

    公开(公告)日：2017-01-03

    申请号：US14235311

    申请日：2012-08-20

    申请人： Koji Noishiki ,  Tomohiro Suzuki ,  Yasutake Miwa

    发明人： Koji Noishiki ,  Tomohiro Suzuki ,  Yasutake Miwa

    IPC分类号： B01J19/00 ,  F16L41/02 ,  F28D9/00

    CPC分类号： F16L41/02 ,  B01J19/00 ,  B01J19/0093 ,  B01J2219/00783 ,  B01J2219/00786 ,  B01J2219/00808 ,  B01J2219/00813 ,  B01J2219/00822 ,  B01J2219/00873 ,  B01J2219/00889 ,  B01J2219/00891 ,  B01J2219/0099 ,  F28D9/00 ,  F28F2260/02 ,  Y10T137/0402 ,  Y10T137/87571 ,  Y10T137/87652

    摘要： A flow passage structure is provided with a fluid flow passage that includes a plurality of straight flow passages, a first return bend that connects the downstream end of the straight flow passage through which a fluid flows from a second end surface toward a first end surface among the plurality of straight flow passages to the upstream end of the straight flow passage which is disposed at the downstream side of the straight flow passage and is adjacent to the straight flow passage, and a second return bend that connects the downstream end of the straight flow passage through which the fluid flows from the first end surface toward the second end surface among the plurality of straight flow passages to the upstream end of the straight flow passage which is disposed at the downstream side of the straight flow passage and is adjacent to the straight flow passage.

    摘要翻译： 流路结构设置有包括多个直流通道的流体流动通道，第一返回弯曲部，其连接流体从第二端面朝向第一端面流动的直流路的下游端，第一返回弯曲部 所述多条直流通道设置在所述直流通道的下游侧并且与所述直流通道相邻的所述直流通道的上游端;以及第二回流弯管，其连接所述直流通道的下游端 多个直流通道中的流体从第一端面朝向第二端面流动的直通流路的上游端，该直流通道的上游端设置在直流通道的下游侧并与直线 流通道

    Fluidic module permanent stack assemblies and methods
    3.
    发明授权
    Fluidic module permanent stack assemblies and methods 有权
    流体模块永久堆栈组件和方法

    公开(公告)号：US09446378B2

    公开(公告)日：2016-09-20

    申请号：US14361842

    申请日：2012-11-30

    申请人： Corning Incorporated

    发明人： Thierry Luc Alain Dannoux ,  Sylvain Maxime F. Gremetz ,  Olivier Lobet ,  Ronan Tanguy

    IPC分类号： B01J19/32 ,  B23P19/10 ,  B01J19/00 ,  C03B23/24 ,  B81C3/00 ,  C03C3/091 ,  C03C27/00

    CPC分类号： B01J19/32 ,  B01J19/0093 ,  B01J2219/00786 ,  B01J2219/00806 ,  B01J2219/00808 ,  B01J2219/00824 ,  B01J2219/00831 ,  B01J2219/32213 ,  B01J2219/32275 ,  B01J2219/32425 ,  B01J2219/32441 ,  B01J2219/328 ,  B23P19/10 ,  B81B2201/058 ,  B81C3/001 ,  B81C2201/019 ,  C03B23/245 ,  C03C3/091 ,  C03C27/00 ,  Y10T29/49904

    摘要： The present disclosure provides an assembled stack of fluidic modules comprising at least first and second fluidic modules assembled in a stacked configuration. The first fluidic module has first and second major planar surfaces and encloses a first fluidic passage extending therethrough from a first passage entrance to a first passage exit with the first passage exit located on the second major planar surface of the first fluidic module. The second fluidic module also has first and second major planar surfaces and encloses a second fluidic passage extending therethrough from a second passage entrance to a second passage exit, with the second passage entrance located on the first major planar surface of the second fluidic module. The second major planar surface of the first fluidic module and the first major planar surface of the second fluidic module are spaced apart and physically joined together by at least three separate glass or glass-ceramic pads fused therebetween, and the at least three pads include at least one pad having no through-hole and at least one pad having a through-hole, with the through-hole forming a sealed fluidic interconnection between the first fluidic passage and the second fluidic passage. A method of forming the assembled stack is also disclosed.

    摘要翻译： 本公开提供了一组流体模块，其包括以堆叠结构组装的至少第一和第二流体模块。 第一流体模块具有第一和第二主平面表面，并且包围第一流体通道，其从第一通道入口延伸到第一通道出口，第一通道出口位于第一流体模块的第二主平面上。 第二流体模块还具有第一和第二主平面表面，并且包围从第二通道入口延伸穿过第二通道出口的第二流体通道，第二通道入口位于第二流体模块的第一主平面上。 第一流体模块的第二主平面表面和第二流体模块的第一主平面表面间隔开并通过至少三个分开的玻璃或玻璃 - 陶瓷垫在其间融合并物理地连接在一起，并且至少三个垫包括在 至少一个不具有通孔的垫和至少一个具有通孔的垫，所述通孔在所述第一流体通道和所述第二流体通道之间形成密封的流体互连。 还公开了一种形成组装堆叠的方法。

    FLOW PASSAGE STRUCTURE AND FLOW PASSAGE STRUCTURE MANUFACTURING METHOD
    5.
    发明申请
    FLOW PASSAGE STRUCTURE AND FLOW PASSAGE STRUCTURE MANUFACTURING METHOD 有权
    流动通道结构和流动通道结构制造方法

    公开(公告)号：US20140166137A1

    公开(公告)日：2014-06-19

    申请号：US14235311

    申请日：2012-08-20

    申请人： Koji Noishiki ,  Tomohiro Suzuki ,  Yasutake Miwa

    发明人： Koji Noishiki ,  Tomohiro Suzuki ,  Yasutake Miwa

    IPC分类号： F16L41/02

    CPC分类号： F16L41/02 ,  B01J19/00 ,  B01J19/0093 ,  B01J2219/00783 ,  B01J2219/00786 ,  B01J2219/00808 ,  B01J2219/00813 ,  B01J2219/00822 ,  B01J2219/00873 ,  B01J2219/00889 ,  B01J2219/00891 ,  B01J2219/0099 ,  F28D9/00 ,  F28F2260/02 ,  Y10T137/0402 ,  Y10T137/87571 ,  Y10T137/87652

    摘要： A flow passage structure is provided with a fluid flow passage that includes a plurality of straight flow passages, a first return bend that connects the downstream end of the straight flow passage through which a fluid flows from a second end surface toward a first end surface among the plurality of straight flow passages to the upstream end of the straight flow passage which is disposed at the downstream side of the straight flow passage and is adjacent to the straight flow passage, and a second return bend that connects the downstream end of the straight flow passage through which the fluid flows from the first end surface toward the second end surface among the plurality of straight flow passages to the upstream end of the straight flow passage which is disposed at the downstream side of the straight flow passage and is adjacent to the straight flow passage.

    摘要翻译： 流路结构设置有包括多个直流通道的流体流动通道，第一返回弯曲部，其连接流体从第二端面朝向第一端面流动的直流路的下游端，第一返回弯曲部 所述多条直流通道设置在所述直流通道的下游侧并且与所述直流通道相邻的所述直流通道的上游端;以及第二回流弯管，其连接所述直流通道的下游端 多个直流通道中的流体从第一端面朝向第二端面流动的直通流路的上游端，该直流通道的上游端设置在直流通道的下游侧并与直线 流通道

    METHOD AND DEVICE FOR MANUFACTURING OF RADIOPHARMACEUTICALS
    7.
    发明申请
    METHOD AND DEVICE FOR MANUFACTURING OF RADIOPHARMACEUTICALS 审中-公开
    用于制造放射线照相的方法和装置

    公开(公告)号：US20120108858A1

    公开(公告)日：2012-05-03

    申请号：US12982499

    申请日：2010-12-30

    申请人： MAXIM KISELEV

    发明人： MAXIM KISELEV

    IPC分类号： C07C25/00

    CPC分类号： C07B59/005 ,  A61K51/0491 ,  B01J19/004 ,  B01J19/0093 ,  B01J2219/00799 ,  B01J2219/00806 ,  B01J2219/00808 ,  B01J2219/00817 ,  B01J2219/00822 ,  B01J2219/00862 ,  B01J2219/00873 ,  B01J2219/00889

    摘要： The invention relates to a device for processing radioisotopes and production of radiopharmaceuticals, for example, 18F-2 Deoxy-2-Fluoro-D-Glucose (FDG), for Positron Emission Tomography (PET). Use of a tilting and rotating reactor with optimized geometry allows for decreased processing time and increased efficiency. Reagent vials are separated from the reactor module and placed in a separate enclosure allowing safe reloading of the system and production of multiple batches with minimal operator exposure to radiation. Reagent vials enclosure is protected from the environment and filled with purified air to reduce risk of contamination. Product and reagents pathways are sealed from the environment and are sterilized.

    摘要翻译： 本发明涉及用于正电子发射断层扫描（PET）的放射性同位素和放射性药物的制备装置，例如18F-2脱氧-2-氟-D-葡萄糖（FDG）。 使用具有优化几何形状的倾斜和旋转反应器可减少加工时间并提高效率。 将试剂瓶与反应器模块分离，并放置在单独的外壳中，允许系统的安全重新装载，并且以最小的操作者暴露于辐射来生产多个批次。 试剂盒外壳受环境保护，并充满净化空气，以减少污染的风险。 产品和试剂通道与环境密封并进行灭菌。

    RIGID DISPOSABLE FLOW PATH
    8.
    发明申请
    RIGID DISPOSABLE FLOW PATH 审中-公开
    刚性流通路径

    公开(公告)号：US20120000566A1

    公开(公告)日：2012-01-05

    申请号：US13170926

    申请日：2011-06-28

    申请人： Martin Morrissey ,  Neil Schauer

    发明人： Martin Morrissey ,  Neil Schauer

    IPC分类号： F16L9/00

    CPC分类号： F16L9/00 ,  B01J19/0093 ,  B01J2219/00783 ,  B01J2219/00808 ,  B01J2219/00813 ,  B01J2219/00833 ,  B01J2219/00968 ,  B01L3/502707 ,  B01L3/502715 ,  B01L3/561 ,  B01L2200/027 ,  B01L2200/0689 ,  B01L2300/0887 ,  F16L9/127 ,  F16L9/133 ,  F16L9/22 ,  Y10T137/87153

    摘要： The present invention provides a disposable rigid flow path which by itself or in conjunction with a clam shell or manifold system provides additional pressure resistance for the disposable device. In a first embodiment, the device is comprised of a first sheet of rigid plastic material and a second sheet of plastic material. Each sheet has a first major surface and a second major surface and a thickness between the first and second major surfaces. At least one and preferably both have flow channels formed in them. The flow channels are formed in the sheet(s) in manner such that the area of the sheet where the flow channels are formed extend away from the first major surface of the sheet and beyond the normal plane of the second major surface of the sheet. The first and second sheets are liquid tightly sealed to each other at their adjoining first major surfaces. In the embodiment where each sheet contains a flow channel, the flow channels of the two sheets are aligned and in register with each other. One or more fittings are secured in the flow channel(s) at an edge of the two liquid tightly sealed sheets so as to function as an inlet, outlet or other port for the system. In another embodiment tubing is placed in the channels before the sheets are secured to one another.

    摘要翻译： 本发明提供了一次性刚性流动路径，其自身或与蛤壳或歧管系统结合为一次性装置提供额外的耐压性。 在第一实施例中，该装置由第一片刚性塑料材料和第二片塑料材料构成。 每个片材具有第一主表面和第二主表面以及第一和第二主表面之间的厚度。 至少一个并且优选地两者都具有在其中形成的流动通道。 流动通道以片材的形式形成，使得形成流动通道的片材的面积远离片材的第一主表面并超过片材的第二主表面的法线平面。 第一和第二片在其邻接的第一主表面彼此液密地密封。 在每个片材包含流动通道的实施例中，两个片材的流动通道彼此对齐并且彼此对准。 一个或多个配件固定在两个液密封片的边缘处的流动通道中，以便用作系统的入口，出口或其他端口。 在另一个实施例中，在片彼此固定之前，将管道放置在通道中。

    Rigid disposable flow path
    10.
    发明授权
    Rigid disposable flow path 有权
    刚性一次性流路

    公开(公告)号：US09494259B2

    公开(公告)日：2016-11-15

    申请号：US14074815

    申请日：2013-11-08

    申请人： EMD Millipore Corporation

    发明人： Martin Morrissey ,  Neil Schauer

    IPC分类号： F16L9/127 ,  F16L9/00 ,  F16L9/133 ,  F16L9/22 ,  B01L3/00 ,  B01J19/00

    CPC分类号： F16L9/00 ,  B01J19/0093 ,  B01J2219/00783 ,  B01J2219/00808 ,  B01J2219/00813 ,  B01J2219/00833 ,  B01J2219/00968 ,  B01L3/502707 ,  B01L3/502715 ,  B01L3/561 ,  B01L2200/027 ,  B01L2200/0689 ,  B01L2300/0887 ,  F16L9/127 ,  F16L9/133 ,  F16L9/22 ,  Y10T137/87153

    摘要： A disposable flow path having a manifold system that provides pressure resistance for the disposable device. The disposable device is comprised of a first rigid plastic sheet and a second rigid plastic sheet. Each sheet has two major surfaces and a thickness between them. At least one sheet surface has flow channels formed in it. The flow channels extend away from a first major surface and beyond the normal plane of a second major surface of the sheet. The sheets are liquid tightly sealed to each other at their adjoining first major surfaces. When each sheet contains a flow channel, the flow channels are aligned and in register with each other. One or more fittings can be secured in the flow channel(s) at an edge of the two liquid tightly sealed sheets. Alternatively, tubing is placed in the channels before the sheets are secured to one another.

    摘要翻译： 一次性流路，其具有为一次性装置提供耐压性的歧管系统。 一次性装置包括第一刚性塑料片和第二刚性塑料片。 每片具有两个主表面和它们之间的厚度。 至少一个片材表面上形成有流动通道。 流动通道远离第一主表面并超过板的第二主表面的法线平面。 片材在相邻的第一主要表面彼此液体密封。 当每个纸张包含流动通道时，流动通道对齐并彼此对准。 一个或多个配件可以固定在两个液密封片的边缘处的流动通道中。 或者，在片彼此固定之前，将管道放置在通道中。