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公开(公告)号:US07919056B2
公开(公告)日:2011-04-05
申请号:US12293188
申请日:2007-03-29
CPC分类号: B01J19/0093 , B01J19/0013 , B01J2219/00783 , B01J2219/00804 , B01J2219/00808 , B01J2219/0081 , B01J2219/00822 , B01J2219/00824 , B01J2219/0086 , B01J2219/00867 , B01J2219/00873 , B01J2219/00889 , B01J2219/00891 , B01J2219/00984 , B01J2219/00997
摘要: A micro-reactor system assembly comprises a stack of at least n process modules (1-6), wherein n is an integer equal to or greater than 1, made from a rigid first material and comprising at least one reactive fluid passage (1A, 1B, 2A, 3A, 6A) for accommodating and guiding a reactive fluid, and at least n+1 heat exchange modules (7, 8) made from a ductile second material other than said first material and comprising at least one heat exchange fluid passage (7A, 8A) for accommodating and guiding a heat exchange fluid, wherein each process module (1-6) is sandwiched between two adjacent heat exchange modules (7, 8).
摘要翻译: 微反应器系统组件包括由刚性第一材料制成的至少n个工艺模块(1-6)的堆叠,其中n是等于或大于1的整数,并且包括至少一个反应流体通道(1A, 1B,2A,3A,6A),用于容纳和引导反应流体,以及至少n + 1个热交换模块(7,8),其由除所述第一材料之外的延性第二材料制成,并且包括至少一个热交换流体通道 (7A,8A),用于容纳和引导热交换流体,其中每个处理模块(1-6)夹在两个相邻的热交换模块(7,8)之间。
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公开(公告)号:US20130338400A1
公开(公告)日:2013-12-19
申请号:US13817972
申请日:2011-08-16
申请人: Nikolaus Bieler , Stefan Ellinger , Martina Furrer , Viktor Ladnak , Constanze Müller , Leo Schmid , Cornelia Zur Täschler
发明人: Nikolaus Bieler , Stefan Ellinger , Martina Furrer , Viktor Ladnak , Constanze Müller , Leo Schmid , Cornelia Zur Täschler
IPC分类号: C07C209/74
CPC分类号: C07C209/74 , Y02P20/582 , C07C211/52
摘要: A process for the chlorination of alkylanilines is provided allowing a highly selective chlorination in the meta-position of the aromatic ring. This is achieved by reacting a mixture comprising the alkylaniline and sulfuric acid with chlorine. This process allows a meta-chlorination with a selectivity of more than 90%.
摘要翻译: 提供烷基苯胺的氯化方法,允许在芳环的间位进行高度选择性氯化。 这是通过使包含烷基苯胺和硫酸的混合物与氯反应来实现的。 该方法允许以大于90%的选择性进行间氯化。
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公开(公告)号:US08287824B2
公开(公告)日:2012-10-16
申请号:US13037643
申请日:2011-03-01
CPC分类号: B01J19/0093 , B01J19/0013 , B01J2219/00783 , B01J2219/00804 , B01J2219/00808 , B01J2219/0081 , B01J2219/00822 , B01J2219/00824 , B01J2219/0086 , B01J2219/00867 , B01J2219/00873 , B01J2219/00889 , B01J2219/00891 , B01J2219/00984 , B01J2219/00997
摘要: A micro-reactor system assembly comprises a stack of at least n process modules (1-6), wherein n is an integer equal to or greater than 1, made from a rigid first material and comprising at least one reactive fluid passage (1A, 1B, 2A, 3A, 6A) for accommodating and guiding a reactive fluid, and at least n+1 heat exchange modules (7, 8) made from a ductile second material other than said first material and comprising at least one heat exchange fluid passage (7A, 8A) for accommodating and guiding a heat exchange fluid, wherein each process module (1-6) is sandwiched between two adjacent heat exchange modules (7, 8).
摘要翻译: 微反应器系统组件包括由刚性第一材料制成的至少n个工艺模块(1-6)的堆叠,其中n是等于或大于1的整数,并且包括至少一个反应流体通道(1A, 1B,2A,3A,6A),用于容纳和引导反应流体,以及至少n + 1个热交换模块(7,8),其由除所述第一材料之外的延性第二材料制成,并且包括至少一个热交换流体通道 (7A,8A),用于容纳和引导热交换流体,其中每个处理模块(1-6)夹在两个相邻的热交换模块(7,8)之间。
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公开(公告)号:US20090270663A1
公开(公告)日:2009-10-29
申请号:US12373636
申请日:2007-07-11
IPC分类号: C07C17/38
CPC分类号: C07F3/02 , B01F5/0603 , B01F5/0606 , B01F13/0059 , B01J19/0093 , B01J2219/00867 , B01J2219/00873 , B01J2219/00889 , B01J2219/00984 , C07B49/00
摘要: The present invention relates to a process for Grignard type reactions comprising mixing at least two fluids in a microreactor having at least two injection points.
摘要翻译: 本发明涉及格利雅型反应方法,包括在具有至少两个注射点的微反应器中混合至少两种流体。
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公开(公告)号:US09193667B2
公开(公告)日:2015-11-24
申请号:US13817972
申请日:2011-08-16
申请人: Nikolaus Bieler , Stefan Ellinger , Martina Furrer , Viktor Ladnak , Constanze Müller , Leo Schmid , Cornelia Zur Täschler
发明人: Nikolaus Bieler , Stefan Ellinger , Martina Furrer , Viktor Ladnak , Constanze Müller , Leo Schmid , Cornelia Zur Täschler
IPC分类号: C07C209/00 , C07C209/74
CPC分类号: C07C209/74 , Y02P20/582 , C07C211/52
摘要: A process for the chlorination of alkylanilines is provided allowing a highly selective chlorination in the meta-position of the aromatic ring. This is achieved by reacting a mixture comprising the alkylaniline and sulfuric acid with chlorine. This process allows a meta-chlorination with a selectivity of more than 90%.
摘要翻译: 提供烷基苯胺的氯化方法,允许在芳环的间位进行高度选择性氯化。 这是通过使包含烷基苯胺和硫酸的混合物与氯反应来实现的。 该方法允许以大于90%的选择性进行间氯化。
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6.
公开(公告)号:US08632734B2
公开(公告)日:2014-01-21
申请号:US11800765
申请日:2007-05-07
申请人: Philippe J Barthe , Nikolaus Bieler , Celine Claude Guermeur , Olivier Lobet , Maxime Moreno , Dominique Roberge , Pierre Woehl
发明人: Philippe J Barthe , Nikolaus Bieler , Celine Claude Guermeur , Olivier Lobet , Maxime Moreno , Dominique Roberge , Pierre Woehl
CPC分类号: B01F13/0059 , B01F5/0603 , B01F5/061 , B01F5/0643 , B01F5/0646 , B01F5/0647 , B01J19/0093 , B01J2219/00783 , B01J2219/00822 , B01J2219/00824 , B01J2219/00831 , B01J2219/00833 , B01J2219/0086 , B01J2219/00873 , B01J2219/00889 , B01J2219/00891 , B01J2219/00997 , F28D9/0075 , F28F2260/02 , Y10T436/2575
摘要: A microreaction device or system (4) includes at least one thermal control fluidic passage (C,E) and a principal working fluidic passage (A) with average cross-sectional area in the range of 0.25 to 100 mm2, and having a primary entrance (92) and multiple secondary entrances (94) with the spacing between secondary entrances (94) having a length along the passage (A) of at least two times the root of the average cross-sectional area of the passage (A). The device or system (4) also includes at least one secondary working fluidic passage (B) having an entrance (102) and multiple exits (106) including a final exit (106), each exit (106) being in fluid communication with a corresponding one of the multiple secondary entrances (94) of the principal fluidic passage (A).
摘要翻译: 微反应装置或系统(4)包括平均横截面积在0.25至100mm 2范围内的至少一个热控流体通道(C,E)和主工作流体通道(A),并且具有主入口 (92)和多个次级入口(94),其中第二入口(94)之间的间隔具有沿着通道(A)的长度为通道(A)的平均横截面积的根部的至少两倍。 装置或系统(4)还包括具有入口(102)和多个出口(106)的至少一个次级工作流体通道(B),多个出口(106)包括最终出口(106),每个出口(106)与 主要流体通道(A)的多个次级入口(94)中的对应的一个。
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公开(公告)号:US08512653B2
公开(公告)日:2013-08-20
申请号:US13434210
申请日:2012-03-29
CPC分类号: B01J19/0093 , B01J19/0013 , B01J2219/00783 , B01J2219/00804 , B01J2219/00808 , B01J2219/0081 , B01J2219/00822 , B01J2219/00824 , B01J2219/0086 , B01J2219/00867 , B01J2219/00873 , B01J2219/00889 , B01J2219/00891 , B01J2219/00984 , B01J2219/00997
摘要: A micro-reactor system assembly comprises a stack of at least n process modules (1-6), wherein n is an integer equal to or greater than 1, made from a rigid first material and comprising at least one reactive fluid passage (1A, 1B, 2A, 3A, 6A) for accommodating and guiding a reactive fluid, and at least n+1 heat exchange modules (7, 8) made from a ductile second material other than said first material and comprising at least one heat exchange fluid passage (7A, 8A) for accommodating and guiding a heat exchange fluid, wherein each process module (1-6) is sandwiched between two adjacent heat exchange modules (7, 8).
摘要翻译: 微反应器系统组件包括由刚性第一材料制成的至少n个工艺模块(1-6)的堆叠,其中n是等于或大于1的整数,并且包括至少一个反应流体通道(1A, 1B,2A,3A,6A),用于容纳和引导反应流体,以及至少n + 1个热交换模块(7,8),其由除所述第一材料之外的延性第二材料制成,并且包括至少一个热交换流体通道 (7A,8A),用于容纳和引导热交换流体,其中每个处理模块(1-6)夹在两个相邻的热交换模块(7,8)之间。
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公开(公告)号:US20110150727A1
公开(公告)日:2011-06-23
申请号:US13037643
申请日:2011-03-01
IPC分类号: B01J8/00
CPC分类号: B01J19/0093 , B01J19/0013 , B01J2219/00783 , B01J2219/00804 , B01J2219/00808 , B01J2219/0081 , B01J2219/00822 , B01J2219/00824 , B01J2219/0086 , B01J2219/00867 , B01J2219/00873 , B01J2219/00889 , B01J2219/00891 , B01J2219/00984 , B01J2219/00997
摘要: A micro-reactor system assembly comprises a stack of at least n process modules (1-6), wherein n is an integer equal to or greater than 1, made from a rigid first material and comprising at least one reactive fluid passage (1A, 1B, 2A, 3A, 6A) for accommodating and guiding a reactive fluid, and at least n+1 heat exchange modules (7, 8) made from a ductile second material other than said first material and comprising at least one heat exchange fluid passage (7A, 8A) for accommodating and guiding a heat exchange fluid, wherein each process module (1-6) is sandwiched between two adjacent heat exchange modules (7, 8).
摘要翻译: 微反应器系统组件包括由刚性第一材料制成的至少n个工艺模块(1-6)的堆叠,其中n是等于或大于1的整数,并且包括至少一个反应流体通道(1A, 1B,2A,3A,6A),用于容纳和引导反应流体,以及至少n + 1个热交换模块(7,8),其由除所述第一材料之外的延性第二材料制成,并且包括至少一个热交换流体通道 (7A,8A),用于容纳和引导热交换流体,其中每个处理模块(1-6)夹在两个相邻的热交换模块(7,8)之间。
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公开(公告)号:US07939698B2
公开(公告)日:2011-05-10
申请号:US12373636
申请日:2007-07-11
IPC分类号: C07C17/38
CPC分类号: C07F3/02 , B01F5/0603 , B01F5/0606 , B01F13/0059 , B01J19/0093 , B01J2219/00867 , B01J2219/00873 , B01J2219/00889 , B01J2219/00984 , C07B49/00
摘要: The present invention relates to a process for Grignard type reactions comprising mixing at least two fluids in a microreactor having at least two injection points.
摘要翻译: 本发明涉及格利雅型反应方法,包括在具有至少两个注射点的微反应器中混合至少两种流体。
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公开(公告)号:US20140322105A1
公开(公告)日:2014-10-30
申请号:US14330278
申请日:2014-07-14
IPC分类号: B01J19/00
CPC分类号: B01J19/0093 , B01J19/0013 , B01J2219/00783 , B01J2219/00804 , B01J2219/00808 , B01J2219/0081 , B01J2219/00822 , B01J2219/00824 , B01J2219/0086 , B01J2219/00867 , B01J2219/00873 , B01J2219/00889 , B01J2219/00891 , B01J2219/00984 , B01J2219/00997
摘要: A micro-reactor system assembly comprises a stack of at least n process modules (1-6), wherein n is an integer equal to or greater than 1, made from a rigid first material and comprising at least one reactive fluid passage (1A, 1B, 2A, 3A, 6A) for accommodating and guiding a reactive fluid, and at least n+1 heat exchange modules (7, 8) made from a ductile second material other than said first material and comprising at least one heat exchange fluid passage (7A, 8A) for accommodating and guiding a heat exchange fluid, wherein each process module (1-6) is sandwiched between two adjacent heat exchange modules (7, 8).
摘要翻译: 微反应器系统组件包括由刚性第一材料制成的至少n个工艺模块(1-6)的堆叠,其中n是等于或大于1的整数,并且包括至少一个反应流体通道(1A, 1B,2A,3A,6A),用于容纳和引导反应流体,以及至少n + 1个热交换模块(7,8),其由除所述第一材料之外的延性第二材料制成,并且包括至少一个热交换流体通道 (7A,8A),用于容纳和引导热交换流体,其中每个处理模块(1-6)夹在两个相邻的热交换模块(7,8)之间。
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