Apparatus, System and Method
    3.
    发明申请
    Apparatus, System and Method 失效
    仪器,系统和方法

    公开(公告)号:US20120070813A1

    公开(公告)日:2012-03-22

    申请号:US13234024

    申请日:2011-09-15

    IPC分类号: G09B23/28

    摘要: This invention provides an apparatus for simulating digestion of a foodstuff, which apparatus comprises: (a) an outer containment vessel into which fluid can be introduced and removed via at least one orifice, and (b) an inner digestion chamber comprising a rigid portion through which the foodstuff can be introduced and a flexible portion which tapers from the rigid portion to an aperture from which the foodstuff can be removed, wherein said inner chamber is securable within the outer vessel such that reversible alteration of fluid pressure within the outer vessel causes reversible partial compression of the flexible portion for mixing foodstuff present therein. The invention also provides systems and methods for simulating digestion of a foodstuff.

    摘要翻译: 本发明提供了一种用于模拟食物消化的装置,该装置包括:(a)外部容纳容器,流体可以经由至少一个孔引入并移除到该外部容器容器中,以及(b)内部消化室,其包括通过 食品可以被引入,并且柔性部分从刚性部分逐渐变细到食物可以从中去除的孔,其中所述内室在外部容器内是可固定的,使得外部容器内的流体压力的可逆变化导致可逆的 用于混合存在于其中的食品的柔性部分的部分压缩。 本发明还提供了用于模拟食物消化的系统和方法。

    Method For Producing Microparticles In A Continuous Phase Liquid
    6.
    发明申请
    Method For Producing Microparticles In A Continuous Phase Liquid 失效
    在连续相液体中生产微粒的方法

    公开(公告)号:US20090315203A1

    公开(公告)日:2009-12-24

    申请号:US12548365

    申请日:2009-08-26

    IPC分类号: C08J3/14

    摘要: A continuous phase liquid and a dispersed phase liquid are permitted to flow together through a co-flow channel. Preferably, the dispersed phase liquid is arranged to flow within the flowing body of the continuous phase liquid in the co-flow channel so that the dispersed phase liquid is sheathed by the continuous phase liquid. The continuous phase and dispersed phase liquids are comminuted into microparticles in the co-flow channel by intermittently blocking the co-flow channel.

    摘要翻译: 允许连续相液体和分散相液体通过共流通道一起流动。 优选地,分散相液体布置成在共流通道中在连续相液体的流动体内流动,使得分散相液体被连续相液体包覆。 连续相和分散相液体通过间歇地阻塞共流通道而在共流通道中粉碎成微粒。

    Method and apparatus for treatment of human or animal cell samples
    7.
    发明授权
    Method and apparatus for treatment of human or animal cell samples 失效
    用于治疗人或动物细胞样品的方法和装置

    公开(公告)号:US5985669A

    公开(公告)日:1999-11-16

    申请号:US875042

    申请日:1997-10-03

    申请人: Jari Palander

    发明人: Jari Palander

    摘要: Apparatus for treatment of human or animal cell samples on a microscopic slide includes an element having a recessed face defined by rails which are adapted to slide on surface of the slide. An opening at the leading edge of the element has a bevelled edge and provides access to a cavity formed between the face and the surface of the slide when the rails bear on the slide. The slide is tilted slightly and a vacuum nozzle is arranged at the lower edge of the slide. An end stop may be clamped to the end of the slide opposite to the end where the nozzle is located and has a bevelled edge complimentary to the bevelled edge of the element for closing the opening. A method of spreading liquid over the surface and the sample involves placing the rails on the surface with the cavity displaced laterally from the sample and the face and surface parallel, dispensing the liquid onto the surface and moving the element relative to the surface whereby the liquid becomes trapped in the cavity, and is spread evenly over the sample. The method also involves removing excess liquid after incubation by exposing the cavity to the vacuum nozzle by sliding the element over the lower edge of the slide and allowing the nozzle to suck the excess liquid away. Further treatment liquid may be added adjacent to the opening during the suction process to provide a second treatment without exposing the sample to air between treatments.

    摘要翻译: PCT No.PCT / AU96 / 00007 Sec。 371日期1997年10月3日第 102(e)日期1997年10月3日PCT 1996年1月4日PCT PCT。 WO96 / 21142 PCT公开号 日期1996年7月11日用于在微观载玻片上治疗人或动物细胞样品的装置包括具有由轨道限定的凹面的元件,其适于在载玻片的表面上滑动。 当元件的前缘处的开口具有倾斜的边缘并且当轨道承载在滑块上时,提供进入形成在滑动件的表面和表面之间的空腔。 滑块稍微倾斜,并且在滑块的下边缘处布置有真空喷嘴。 端部止动件可以被夹紧到滑块的与喷嘴所在的端部相对的端部,并且具有与元件的斜边缘互补的用于关闭开口的倾斜边缘。 在表面和样品上铺展液体的方法包括将轨道放置在表面上,其中空腔从样品横向偏移并且面和表面平行,将液体分配到表面上并使元件相对于表面移动,由此液体 被困在腔中,并均匀分布在样品上。 该方法还包括通过将元件滑动在滑块的下边缘上并使喷嘴吸收多余的液体而将孵化后的多余液体暴露于真空喷嘴。 在抽吸过程中可以在开口附近添加另外的处理液体以提供第二处理,而不将样品暴露在处理之间的空气中。

    Apparatus, System and Method
    9.
    发明申请
    Apparatus, System and Method 有权
    仪器,系统和方法

    公开(公告)号:US20080206728A1

    公开(公告)日:2008-08-28

    申请号:US11995062

    申请日:2006-07-18

    IPC分类号: G09B23/30

    摘要: This invention provides an apparatus for simulating digestion of a foodstuff, which apparatus comprises: (a) an outer containment vessel into which fluid can be introduced and removed via at least one orifice, and (b) an inner digestion chamber comprising a rigid portion (240) through which the foodstuff can be introduced and a flexible portion (250) which tapers from the rigid portion to an aperture (260) from which the foodstuff can be removed wherein said inner chamber is seχurable within the outer vessel such that reversible alteration of fluid pressure within the outer vessel causes reversible partial compression of the flexible portion for mixing foodstuff present therein. Also provided is an apparatus for simulating mechanical digestion of a foodstuff, which apparatus comprises: (a) an outer cylinder (534) including in a first end wall an entry port through which the foodstuff can be introduced, and at the opposite second end an opening for receiving an inner cylinder (532), and in the side wall proximal to the first end wall an exit port from which the foodstuff can be removed, (b) an inner cylinder (533) slidably mounted within the outer cylinder and including in a first end wall an aperture through which the foodstuff can be reversibly forced between the inner and outer cylinders, and at the opposite second end an opening for receiving a plunger, and (c) a plunger slidably (530) mounted within the inner cylinder for drawing the foodstuff through the entry port and aperture into the inner cylinder, wherein the aperture is within a resilient diaphragm secured within the end wall of the inner cylinder, and wherein the volume of the inner cylinder is between 20 and 200 ml. The invention also provides systems and methods for simulating digestion of a foodstuff.

    摘要翻译: 本发明提供了一种用于模拟食物消化的装置,该装置包括:(a)外部容纳容器,流体可以通过至少一个孔口被引入和移除,以及(b)内部消化室,其包括刚性部分 240),通过所述柔性部分(250)从所述刚性部分逐渐变细到所述孔(260),所述食物可以从所述孔(260)逐渐变细,所述内部腔可在所述外部容器内被可靠地改变, 外部容器内的流体压力导致用于混合存在于其中的食品的柔性部分的可逆部分压缩。 还提供了一种用于模拟食品的机械消化的装置,该装置包括:(a)外筒(534),其在第一端壁中包括入口,食物可通过该入口入口,并且在相对的第二端 用于容纳内筒(532)的开口,以及在靠近第一端壁的侧壁中可以移除食物的出口,(b)可滑动地安装在外筒内的内筒, 所述第一端壁是所述食物通过所述孔可逆地在所述内圆柱体和所述内圆筒之间被迫动,并且在相对的第二端处具有用于接收柱塞的开口,以及(c)安装在所述内圆筒内的可滑动(530)的柱塞, 将食物通过入口和孔抽入内筒,其中孔位于固定在内筒的端壁内的弹性膜内,并且其中内圆柱体的体积 r在20和200毫升之间。 本发明还提供了用于模拟食物消化的系统和方法。

    Disposable mixing system
    10.
    发明授权
    Disposable mixing system 失效
    一次性混合系统

    公开(公告)号:US07377686B2

    公开(公告)日:2008-05-27

    申请号:US10819806

    申请日:2004-04-07

    申请人: John Dana Hubbard

    发明人: John Dana Hubbard

    IPC分类号: B01F13/00

    摘要: The present invention uses one or more bags that are capable of being selectively pressurized and deflated in conjunction with a disposable bio bag such as a fermenter, mixing bag, storage bag and the like. The pressure bag(s) may surround a selected outer portion of the bag or may be contained within an inner portion of such a bag. By selectively pressurizing and deflating the pressure bag(s), one is able to achieve fluid motion in the bag thereby ensuring cell suspension, mixing and gas transfer within the bag without damaging shear forces or foam generation.

    摘要翻译: 本发明使用一种或多种能够与一次性生物袋如发酵罐,混合袋,储存袋等一起选择性加压和放气的袋子。 压力袋可以围绕袋的选定的外部部分,或者可以包含在这种袋的内部。 通过选择性地加压和放气压力袋,人们能够在袋中实现流体运动,从而确保袋内的细胞悬浮,混合和气体传递而不损害剪切力或发泡。