公开(公告)号：US20240252818A1

公开(公告)日：2024-08-01

申请号：US18485642

申请日：2023-10-12

Applicant: BlephEx, LLC

Inventor： James M. RYNERSON

IPC: A61N1/32 ,  A61N1/04 ,  A61N1/08 ,  A61N1/20 ,  A61N1/36

CPC classification number: A61N1/328 ,  A61N1/205 ,  A61N1/323 ,  A61N1/3601 ,  A61N1/36034 ,  A61N1/0492 ,  A61N2001/083

Abstract: Provided are methods and devices for treating skin conditions using an electrical signal applied to the skin of a subject.

公开(公告)号：US20240216686A1

公开(公告)日：2024-07-04

申请号：US18608885

申请日：2024-03-18

Applicant: Advanced Neuromodulation Systems, Inc.

Inventor： Simeng Zhang ,  Hyun-Joo Park ,  Erika Ross

IPC: A61N1/36 ,  A61N1/04 ,  A61N1/06 ,  A61N1/32

CPC classification number: A61N1/36034 ,  A61N1/0456 ,  A61N1/0492 ,  A61N1/06 ,  A61N1/323

Abstract: A noninvasive/minimally invasive neuromodulation system and method for providing therapy to a target neural tissue of a patient. In one arrangement, an example method comprises applying at least two input waveforms to respective pairs of electrodes affixed on the patient's skin or subcutaneously disposed relative to the target neural tissue, wherein the frequencies of the input waveforms are configured such that they combine, when simultaneously applied, to generate a beat waveform having a beat frequency due to interference. The beat waveform is causative of a transcutaneous/subcutaneous temporal interference (T/STI) electric field generated in the patient body, the T/STI electric field including an interference region at least partially overlapping the target neural tissue of the patient, wherein the beat frequency is of a value operative to impart a therapeutic effect to the target neural tissue.

公开(公告)号：US20190184157A1

公开(公告)日：2019-06-20

申请号：US15857361

申请日：2017-12-28

Applicant: Industrial Technology Research Institute ,  KAOHSIUNG MEDICAL UNIVERSITY

Inventor： Chia-Chan HSU ,  Chao-Jen HUANG ,  Su-Shin LEE

IPC: A61N1/32 ,  A61N1/36 ,  A61N1/04

CPC classification number: A61N1/328 ,  A61N1/0476 ,  A61N1/323 ,  A61N1/326 ,  A61N1/36017

Abstract: An electrical stimulation control circuit including a pulse generator, a processing circuit and an electrode is provided. The pulse generator is configured to generate a switching signal. The processing circuit generates an energy signal according to the switching signal. The electrode is configured to contact the skin of a living body and includes a first comb electrode and a second comb electrode. The first comb electrode receives the energy signal and includes a plurality of first electrodes. The first electrodes are electrically connected to each other and extended along a first direction. The second comb electrode receives a ground signal and includes a plurality of second electrodes. The second electrodes are electrically connected to each other and extended along a second direction opposite to the first direction. The first electrodes and the second electrodes are arranged in a staggered manner and electrically insulated from each other.

公开(公告)号：US09943683B2

公开(公告)日：2018-04-17

申请号：US15666362

申请日：2017-08-01

Applicant: DJO, LLC

Inventor： Thomas Jerome Bachinski ,  Richard Paul Shindley ,  Dennis Lutz

IPC: A61N1/00 ,  A61N1/08 ,  A61N1/32 ,  A61N1/372 ,  A61N1/04 ,  A61N1/36 ,  A61N1/02 ,  G06F19/00 ,  A61N1/375

CPC classification number: A61N1/08 ,  A61B2560/0456 ,  A61N1/025 ,  A61N1/0412 ,  A61N1/0428 ,  A61N1/0452 ,  A61N1/0456 ,  A61N1/0468 ,  A61N1/0472 ,  A61N1/048 ,  A61N1/0484 ,  A61N1/0492 ,  A61N1/323 ,  A61N1/325 ,  A61N1/36014 ,  A61N1/36021 ,  A61N1/37211 ,  A61N1/37264 ,  A61N1/3756 ,  A61N2001/083 ,  G16H40/63

Abstract: A patch for a therapeutic electrical stimulation device includes a shoe connected to the first side of the patch, the shoe including a body extending in a longitudinal direction from a first end to a second end, and having first and second surfaces, the first end of the shoe defining at least two ports, and the first surface of the shoe defining a connection member. The patch also includes at least one conductor positioned in the ports of the first end of the shoe. The shoe is configured for sliding insertion into a receptacle defined by a controller so that the conductor is connected to the controller to deliver electrical current from the controller, through the conductor, and to the electrodes, and the connection member is at least partially captured by a detent defined by the controller in the receptacle to retain the shoe within the receptacle.

公开(公告)号：US20180021574A1

公开(公告)日：2018-01-25

申请号：US15689608

申请日：2017-08-29

Applicant: Medtronic Ardian Luxembourg S.a.r.l.

Inventor： Denise Zarins

IPC: A61N1/36 ,  A61N1/32 ,  A61B18/14 ,  A61N1/20 ,  A61B18/12 ,  A61N1/05 ,  A61F7/10 ,  A61B18/00 ,  A61F7/12

CPC classification number: A61N1/36007 ,  A61B18/1206 ,  A61B18/1492 ,  A61B2018/0022 ,  A61B2018/00267 ,  A61B2018/00404 ,  A61B2018/00434 ,  A61B2018/00511 ,  A61B2018/00577 ,  A61B2018/00613 ,  A61F7/10 ,  A61F2007/126 ,  A61N1/05 ,  A61N1/0507 ,  A61N1/0551 ,  A61N1/0558 ,  A61N1/205 ,  A61N1/323 ,  A61N1/326 ,  A61N1/327 ,  A61N1/3605 ,  A61N1/36114 ,  A61N1/36117

Abstract: Methods and apparatus are provided for multi-vessel neuromodulation, e.g., via a pulsed electric field. Such multi-vessel neuromodulation may effectuate irreversible electroporation or electrofusion, necrosis and/or inducement of apoptosis, alteration of gene expression, action potential attenuation or blockade, changes in cytokine up-regulation and other conditions in target neural fibers. In some embodiments, the multi-vessel neuromodulation is applied to neural fibers that contribute to renal function. Such multi-vessel neuromodulation optionally may be performed bilaterally.

公开(公告)号：US09737705B2

公开(公告)日：2017-08-22

申请号：US15178468

申请日：2016-06-09

Applicant: EMPI Inc.

Inventor： Thomas Jerome Bachinski ,  Richard Paul Shindley ,  Dennis Lutz

IPC: A61N1/00 ,  A61N1/08 ,  A61N1/02 ,  A61N1/04 ,  A61N1/36 ,  A61N1/32 ,  A61N1/372 ,  A61N1/375 ,  G06F19/00

CPC classification number: A61N1/08 ,  A61B2560/0456 ,  A61N1/025 ,  A61N1/0412 ,  A61N1/0428 ,  A61N1/0452 ,  A61N1/0456 ,  A61N1/0468 ,  A61N1/0472 ,  A61N1/048 ,  A61N1/0484 ,  A61N1/0492 ,  A61N1/323 ,  A61N1/325 ,  A61N1/36014 ,  A61N1/36021 ,  A61N1/37211 ,  A61N1/37264 ,  A61N1/3756 ,  A61N2001/083 ,  G16H40/63

Abstract: A patch for a therapeutic electrical stimulation device includes a shoe connected to the first side of the patch, the shoe including a body extending in a longitudinal direction from a first end to a second end, and having first and second surfaces, the first end of the shoe defining at least two ports, and the first surface of the shoe defining a connection member. The patch also includes at least one conductor positioned in the ports of the first end of the shoe. The shoe is configured for sliding insertion into a receptacle defined by a controller so that the conductor is connected to the controller to deliver electrical current from the controller, through the conductor, and to the electrodes, and the connection member is at least partially captured by a detent defined by the controller in the receptacle to retain the shoe within the receptacle.

公开(公告)号：US20160317383A1

公开(公告)日：2016-11-03

申请号：US15108598

申请日：2014-12-31

Applicant: IFTECH INVENTING FUTURE TECHNOLOGY INC.

Inventor： Michael Gerald STANFIELD ,  Brodie Myles STANFIELD

IPC: A61H23/02 ,  A61N1/32 ,  A41D13/12 ,  A61B5/00 ,  A61F7/02 ,  A61N1/04 ,  A61N1/36

CPC classification number: A61H23/0254 ,  A41D13/12 ,  A61B5/0533 ,  A61B5/6804 ,  A61B2562/0204 ,  A61F7/02 ,  A61F2007/0234 ,  A61H3/061 ,  A61H9/0078 ,  A61H23/0236 ,  A61H23/0245 ,  A61H23/04 ,  A61H99/00 ,  A61H2003/063 ,  A61H2201/025 ,  A61H2201/10 ,  A61H2201/1614 ,  A61H2201/1619 ,  A61H2201/1623 ,  A61H2201/1628 ,  A61H2201/1635 ,  A61H2201/164 ,  A61H2201/165 ,  A61H2201/501 ,  A61H2201/5015 ,  A61H2201/5043 ,  A61H2201/5046 ,  A61H2201/5097 ,  A61H2205/06 ,  A61H2230/04 ,  A61H2230/06 ,  A61H2230/30 ,  A61H2230/40 ,  A61H2230/50 ,  A61N1/0452 ,  A61N1/0456 ,  A61N1/0484 ,  A61N1/323 ,  A61N1/36014

Abstract: A garment with prepositioned, definite sensory stimulating devices attached. These sensory stimulating devices include, but are not limited to, electrical stimulation, audio and physical stimulation such as localised force generation, compression, constriction, vibration, and surround sound. Predetermined and defined actuators allow the wearer to receive tissue, nerve and/or muscle stimulation and/or contraction so that the stimulation is precise as determined by its ability to conform to the scientific methodology of repeatability, reproducibility and reliability; this being due to consistency of actuator positioning in one or multiple locals on the human body. A personal surround sound can also be integrated to the garment to ensure the wearer is always in the optimal position relative the speakers. These actuators can be force generators within the garment for the wearer to feel impact or apparatus or electrodes included in the garment to locally constrict and increase pressure on the wearer.

Abstract translation: 附有预定位，确定感觉刺激装置的服装。 这些感觉刺激装置包括但不限于电刺激，音频和物理刺激，例如局部力产生，压缩，收缩，振动和环绕声。 预定和定义的致动器允许穿着者接受组织，神经和/或肌肉刺激和/或收缩，使得刺激是精确的，其由其符合可重复性，再现性和可靠性的科学方法的能力确定; 这是由于致动器定位在人体上的一个或多个本地人的一致性。 个人环绕声还可以集成到衣服中，以确保佩戴者总是处于相对于扬声器的最佳位置。 这些致动器可以是衣服内的力发生器，用于穿着者感觉到衣服中包含的冲击或装置或电极，以局部收缩并增加穿着者的压力。

公开(公告)号：US20160287866A1

公开(公告)日：2016-10-06

申请号：US15178468

申请日：2016-06-09

Applicant: EMPI Inc.

Inventor： Thomas Jerome Bachinski ,  Richard Paul Shindley ,  Dennis Lutz

IPC: A61N1/08 ,  A61N1/02 ,  A61N1/36 ,  A61N1/04 ,  A61N1/32

CPC classification number: A61N1/08 ,  A61B2560/0456 ,  A61N1/025 ,  A61N1/0412 ,  A61N1/0428 ,  A61N1/0452 ,  A61N1/0456 ,  A61N1/0468 ,  A61N1/0472 ,  A61N1/048 ,  A61N1/0484 ,  A61N1/0492 ,  A61N1/323 ,  A61N1/325 ,  A61N1/36014 ,  A61N1/36021 ,  A61N1/37211 ,  A61N1/37264 ,  A61N1/3756 ,  A61N2001/083 ,  G16H40/63

Abstract: A patch for a therapeutic electrical stimulation device includes a shoe connected to the first side of the patch, the shoe including a body extending in a longitudinal direction from a first end to a second end, and having first and second surfaces, the first end of the shoe defining at least two ports, and the first surface of the shoe defining a connection member. The patch also includes at least one conductor positioned in the ports of the first end of the shoe. The shoe is configured for sliding insertion into a receptacle defined by a controller so that the conductor is connected to the controller to deliver electrical current from the controller, through the conductor, and to the electrodes, and the connection member is at least partially captured by a detent defined by the controller in the receptacle to retain the shoe within the receptacle.

公开(公告)号：US20160220782A1

公开(公告)日：2016-08-04

申请号：US15095147

申请日：2016-04-10

Applicant: James Otis

Inventor： James Otis

IPC: A61M21/00 ,  A61N1/36 ,  A61N5/06

CPC classification number: A61M21/00 ,  A61M21/02 ,  A61M2021/0022 ,  A61M2021/0027 ,  A61M2021/0044 ,  A61M2021/0055 ,  A61M2021/0072 ,  A61M2205/584 ,  A61N1/323 ,  A61N1/36025 ,  A61N5/0618 ,  A61N5/0622 ,  A61N2005/0651

Abstract: In exemplary implementations of this invention, stimuli are intermittently presented to the left or right side of a user. For example, this invention may comprise a method of presenting stimuli to a bilateral organism, which organism has a left side and a right side, wherein: (a) the stimuli are produced by at least one transducer, (b) the stimuli include an intermittent beat train, and (c) the beat train has a beat frequency that is substantially equal to 7.8×(1.618)n Hz, where n is an even integer, which even integer may be negative, zero or positive.

Abstract translation: 在本发明的示例性实现中，刺激被间歇地呈现给用户的左侧或右侧。 例如，本发明可以包括向双侧生物呈现刺激的方法，所述生物体具有左侧和右侧，其中：（a）刺激由至少一个换能器产生，（b）刺激包括 （c）节拍列具有基本上等于7.8×（1.618）n Hz的拍频，其中n是偶数整数，偶数整数可以是负的，零或正的。

公开(公告)号：US20160199662A1

公开(公告)日：2016-07-14

申请号：US14916011

申请日：2014-09-05

Applicant: EBS TECHNOLOGIES GMBH

Inventor： Ingo Wundrich ,  Udo Warschewske

IPC: A61N2/00 ,  A61N1/36

CPC classification number: A61N2/002 ,  A61N1/0456 ,  A61N1/0484 ,  A61N1/323 ,  A61N1/36014 ,  A61N1/36025 ,  A61N1/36046 ,  A61N1/36103 ,  A61N2/006 ,  A61N2/02

Abstract: The invention relates to a system for electrical and/or magnetic neuronal stimulation, comprising a signal generator for generating a stimulation signal, in particular an alternating-current stimulation signal, an applicator for applying the stimulation signal, in particular in an area on or directly around the optic nerve, a lead for deriving a measurement signal, in particular an EEG signal, a biomarker calculation unit for calculating a biomarker based on the measurement signal, and an optimization unit, in particular for performing a stochastic optimization process, for optimizing the value of the biomarker by varying the stimulation signal.

Abstract translation: 本发明涉及一种用于电和/或磁神经元刺激的系统，包括用于产生刺激信号，特别是交流刺激信号的信号发生器，用于施加刺激信号的施加器，特别是在或直接 围绕视神经，用于导出测量信号的导线，特别是EEG信号，用于基于测量信号计算生物标志物的生物标志物计算单元，以及优化单元，特别是用于执行随机优化过程，用于优化 通过改变刺激信号的生物标志物的价值。