公开(公告)号：US12053610B2

公开(公告)日：2024-08-06

申请号：US15672691

申请日：2017-08-09

申请人： Kimberley Levy ,  Frank Levy

发明人： Kimberley Levy ,  Frank Levy

IPC分类号： A61M39/22 ,  A61M5/00 ,  A61M5/19 ,  A61M5/178 ,  A61M39/00 ,  A61M39/24

CPC分类号： A61M5/007 ,  A61M5/19 ,  A61M39/223 ,  A61M2005/006 ,  A61M2005/1787 ,  A61M2039/0009 ,  A61M2039/0027 ,  A61M39/24 ,  A61M2202/0225 ,  F04C2270/0421

摘要： A system for controlled delivery of medical fluids to a patient includes an inlet conduit attached to a source of a medical fluid and an outlet conduit connected to the patient. The inlet and outlet conduits are interconnected by a multiple stage control valve assembly and a pair of syringes. The control valve assembly is alternated between a first state wherein the inlet conduit communicates with a first syringe for transmitting fluid from the source to the first syringe, a second state wherein the first syringe communicates with a second syringe and is isolated from the inlet conduit and the outlet for transmitting fluid from the first syringe to the second syringe, and a third state wherein the second syringe communicates with the outlet and is isolated from the inlet and the first syringe for transmitting fluid from the second syringe to the patient through the outlet.

公开(公告)号：US11925764B2

公开(公告)日：2024-03-12

申请号：US17461484

申请日：2021-08-30

申请人： VERO Biotech Inc.

发明人： David H. Fine

IPC分类号： A61K33/00 ,  A61K31/655 ,  A61K47/02 ,  A61M5/165 ,  A61M15/00 ,  A61M15/08 ,  A61M16/10 ,  A61M16/12 ,  A61M35/00 ,  A61K9/00 ,  A61K9/70 ,  A61M5/00

CPC分类号： A61M16/12 ,  A61K31/655 ,  A61K33/00 ,  A61K47/02 ,  A61M5/165 ,  A61M15/00 ,  A61M15/08 ,  A61M15/085 ,  A61M16/105 ,  A61M35/006 ,  A61K9/0043 ,  A61K9/0073 ,  A61K9/7023 ,  A61M2005/006 ,  A61M2202/0275 ,  A61M2205/75

摘要： A method for delivering nitric oxide therapy to a subject can include administering a composition including a nitric-oxide releasing agent and silica to the subject and releasing a therapeutic amount of nitric oxide from the composition.

公开(公告)号：US11701256B2

公开(公告)日：2023-07-18

申请号：US16271138

申请日：2019-02-08

申请人： Novartis AG

发明人： Mark Alan Hopkins

IPC分类号： A61F9/007 ,  A61F9/00 ,  A61K9/00 ,  A61K31/02 ,  A61K33/16 ,  A61M5/178 ,  A61M13/00 ,  B65B31/02 ,  F17C5/06 ,  B65B3/00 ,  A61M37/00 ,  A61M5/00

CPC分类号： A61F9/00727 ,  A61F9/0008 ,  A61F9/00736 ,  A61K9/0048 ,  A61K31/02 ,  A61K33/16 ,  A61M5/1782 ,  A61M13/003 ,  A61M37/00 ,  B65B3/003 ,  B65B31/025 ,  F17C5/06 ,  A61M2005/006 ,  A61M2202/02 ,  A61M2205/3317 ,  A61M2210/0612

摘要： A gas mixing system for providing mixed gas for intraocular injection. In some embodiments, a first fixed-volume chamber is automatically purged and filled with gas from a first gas supply input, to a first predetermined pressure. A second fixed-volume chamber is purged and filled with gas from a second gas supply input, to a second predetermined pressure. The first and second predetermined pressures are determined based on a desired concentration of gases in the final mix, and the respective volumes of the first and second fixed-volume chambers and of a third fixed-volume chamber. Gas from the first fixed-volume chamber is then allowed to mix with gas in the third fixed-volume chamber, which was previously purged. Next, gas from the second fixed-volume chamber is allowed to mix with gas in the third fixed-volume chamber. Finally, the mixture of gases in the third fixed-volume chamber is expressed into an intraocular syringe.

公开(公告)号：US11701215B2

公开(公告)日：2023-07-18

申请号：US16266687

申请日：2019-02-04

申请人： Giner, Inc.

发明人： Linda Tempelman ,  Simon Stone ,  Klearchos Papas

IPC分类号： A61F2/02 ,  A61M5/142 ,  A61M5/00 ,  A61K48/00

CPC分类号： A61F2/022 ,  A61K48/0075 ,  A61M2005/006 ,  A61M2005/14204 ,  A61M2202/0208 ,  A61M2205/7536

摘要： System for gas treatment of cellular implants. The system enhances the viability and function of cellular implants, particularly those with high cellular density, for use in human or veterinary medicine. The system utilizes a miniaturized electrochemical gas generator subsystem that continuously supplies oxygen and/or hydrogen to cells within an implantable and immunoisolated cell containment subsystem to facilitate cell viability and function at high cellular density while minimizing overall implant size. The cell containment subsystem is equipped with features to allow gas delivery through porous tubing or gas-only permeable internal gas compartments within the implantable cell containment subsystem. Furthermore, the gas generator subsystem includes components that allow access to water for electrolysis while implanted, thereby promoting long-term implantability of the gas generator subsystem. An application of the system is a pancreatic islet (or pancreatic islet analogue) implant for treatment of Type 1 diabetes (T1D) that would be considered a bio-artificial pancreas.

公开(公告)号：US20180317932A1

公开(公告)日：2018-11-08

申请号：US15588698

申请日：2017-05-08

申请人： William H'Doubler

发明人： William H'Doubler

IPC分类号： A61B17/12 ,  A61M5/00 ,  A61M25/10 ,  A61M25/00

CPC分类号： A61B17/12136 ,  A61B17/1204 ,  A61B17/12109 ,  A61M5/007 ,  A61M25/005 ,  A61M25/0052 ,  A61M25/007 ,  A61M25/0662 ,  A61M25/10182 ,  A61M2005/006 ,  A61M2025/0076 ,  A61M2025/105 ,  A61M2025/1052 ,  A61M2202/0225 ,  A61M2202/0478

摘要： The disclosure sets forth various exemplary embodiments of systems, methods, and/or medical apparatuses including but not limited to: a sheath; and a balloon disposed at a working distal end of the sheath. According to one example embodiment the medical device can include where the sheath can include woven wire reinforcing axial and longitudinal strength, side holes, a one direction distal valve, and can include an inflator. According to one example embodiment the medical device can include where the sheath can include a narrow cross-section of, e.g., 7-8 Fr and balloon of length of, e.g., 12 cm.

公开(公告)号：US09700680B2

公开(公告)日：2017-07-11

申请号：US15064306

申请日：2016-03-08

申请人： Medtrick Inc

发明人： Ajay Sharma

IPC分类号： A61M5/00 ,  A61M5/315 ,  A61B8/08 ,  A61M5/19 ,  A61M25/01 ,  A61M16/06 ,  A61M16/10

CPC分类号： A61M5/31596 ,  A61B8/0841 ,  A61B8/0883 ,  A61B8/481 ,  A61M5/002 ,  A61M5/007 ,  A61M5/19 ,  A61M5/315 ,  A61M16/06 ,  A61M16/10 ,  A61M25/0108 ,  A61M2005/006 ,  A61M2005/31598 ,  A61M2210/125

摘要： A dedicated device for detection of vascular shunts can include a first chamber, a second chamber, and a third chamber. The first chamber can be configured to hold liquid, the second chamber to hold gas, and the third chamber can be in communication with the first and second chambers. The third chamber can include small-scale geometric features configured to produce gas bubbles as liquid from the first chamber and gas from the second chamber simultaneously flow into the third chamber. The device can also include a device opening in communication with the third chamber such that a mixture of liquid and gas bubbles can flow out of the device opening. The device can also include a plunger configured to force the liquid and the gas simultaneously from the first and second chambers, through the third chamber to mix with each other and produce bubbles, and further through the device opening.

公开(公告)号：US20170136174A1

公开(公告)日：2017-05-18

申请号：US14944574

申请日：2015-11-18

申请人： Frank Levy ,  Kimberley Levy

发明人： Frank Levy ,  Kimberley Levy

IPC分类号： A61M5/00 ,  A61M39/22 ,  A61M5/19 ,  A61M13/00

CPC分类号： A61M5/007 ,  A61M5/19 ,  A61M13/003 ,  A61M39/223 ,  A61M2005/006 ,  A61M2202/0225 ,  A61M2205/073 ,  A61M2202/0007

摘要： A delivery system for the effective, reliable and foolproof delivery of controlled amounts of a medical grade gas to a patient includes a compressed gas unit composed of a vacuum sealed bag to which is secured at least one compressed gas cartridge and a multi-part valve delivery system.

公开(公告)号：US20170056594A1

公开(公告)日：2017-03-02

申请号：US15118635

申请日：2015-07-21

申请人： Joong Suk Jin ,  Se Hoon Chin

发明人： Se Hoon Chin

IPC分类号： A61M5/31 ,  A61M5/19 ,  A61M5/34

CPC分类号： A61M5/3129 ,  A61M5/178 ,  A61M5/19 ,  A61M5/347 ,  A61M2005/006 ,  A61M2005/1787 ,  A61M2005/3128

摘要： A syringe mechanism for the auto-regeneration of the dermis is provided. The syringe mechanism includes: a liquid syringe filled with liquid in a cylinder thereof, a piston inserted into a top of the cylinder, a discharge portion formed at a bottom portion of the cylinder, and screw threads formed around the discharge portion; and an injecting member having a cylindrical body portion, an inlet portion formed to be inserted and coupled with the discharge portion at a top end of the cylindrical body portion, and a coupling portion formed to be coupled with the screw threads around the inlet portion, the screw threads and the coupling portion rotated and inserted so as to be fastened to the liquid syringe so that liquid is injected into the top portion of the body portion via the liquid syringe.

摘要翻译： 提供了一种用于真皮自动再生的注射器机构。 注射器机构包括：在其圆柱体中充满液体的液体注射器，插入到气缸的顶部的活塞，形成在气缸的底部的排出部分和形成在排出部分周围的螺纹; 以及具有圆柱形主体部分的注入构件，形成为在所述圆柱形主体部分的顶端处与所述排出部分插入并联接的入口部分，以及形成为与所述螺纹线围绕所述入口部分联接的联接部分， 螺纹和连接部分旋转并插入，以便紧固到液体注射器，使得液体经由液体注射器注入到主体部分的顶部。

公开(公告)号：US20160263328A1

公开(公告)日：2016-09-15

申请号：US15063264

申请日：2016-03-07

申请人： Tom H Williamson Ltd.

发明人： Thomas Hardie WILLIAMSON ,  Edward John GOODWIN

IPC分类号： A61M5/315 ,  G09F3/00 ,  G09F3/04 ,  A61M5/00

CPC分类号： A61M5/31525 ,  A61M5/3129 ,  A61M2005/006 ,  A61M2005/3114 ,  A61M2005/3126 ,  G09F3/0295 ,  G09F3/04 ,  G09F23/00

摘要： A flexible self-adhesive label (10), for a syringe (200) comprising a barrel (210) with a front end and a rear end and having a tip (220) at the front end of the barrel. The label comprises a main body (20), for labelling the barrel of the syringe, the main body having a front end and a rear end. The label further comprises a tongue (30) at the front end of the main body. The tongue includes an aperture (32) for engaging with the tip of the syringe, for locating the main body (20) of the label in a longitudinal direction with respect to the barrel. Also provided is a method of labelling and filling a syringe, using the label.

摘要翻译： 一种用于注射器（200）的柔性自粘标签（10），包括具有前端和后端的筒体（210），并且在枪管的前端具有尖端（220）。 标签包括用于标记注射器的筒体的主体（20），主体具有前端和后端。 标签还包括位于主体前端的舌部（30）。 舌头包括用于与注射器的尖端接合的孔（32），用于沿着相对于枪管的纵向方向定位标签的主体（20）。 还提供了使用标签来标记和填充注射器的方法。

公开(公告)号：US20160151598A1

公开(公告)日：2016-06-02

申请号：US14948992

申请日：2015-11-23

申请人： GENO LLC

发明人： David H. Fine, I

IPC分类号： A61M16/12 ,  A61M16/10

CPC分类号： A61M16/12 ,  A61K9/0043 ,  A61K9/0073 ,  A61K9/7023 ,  A61K31/655 ,  A61K33/00 ,  A61K47/02 ,  A61M5/165 ,  A61M15/00 ,  A61M15/08 ,  A61M15/085 ,  A61M16/105 ,  A61M35/006 ,  A61M2005/006 ,  A61M2202/0275 ,  A61M2205/75

摘要： A method for delivering nitric oxide therapy to a subject can include administering a composition including a nitric-oxide releasing agent and silica to the subject and releasing a therapeutic amount of nitric oxide from the composition.

摘要翻译： 将一氧化氮治疗用于对象的方法可以包括向受试者施用包含一氧化氮释放剂和二氧化硅的组合物，并从组合物中释放治疗量的一氧化氮。