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公开(公告)号：US20240252648A1
公开(公告)日：2024-08-01
申请号：US18462080
申请日：2023-09-06
发明人： Dov Tamarkin , Elana Gazal , Yohan Hazot , David Schuz , Irakliy Papiashvili
IPC分类号： A61K47/44 , A61K8/31 , A61K8/34 , A61K8/36 , A61K9/00 , A61K9/12 , A61K31/137 , A61K31/192 , A61K31/4164 , A61K31/57 , A61K31/573 , A61K31/593 , A61K31/65 , A61K45/06 , A61K47/02 , A61K47/06 , A61K47/10 , A61K47/12 , A61K47/24 , A61Q17/04 , A61Q19/00 , A61Q19/10
CPC分类号： A61K47/44 , A61K8/31 , A61K8/342 , A61K8/361 , A61K9/0014 , A61K9/0048 , A61K9/12 , A61K9/122 , A61K9/124 , A61K31/137 , A61K31/192 , A61K31/4164 , A61K31/57 , A61K31/573 , A61K31/593 , A61K31/65 , A61K45/06 , A61K47/02 , A61K47/06 , A61K47/10 , A61K47/12 , A61K47/24 , A61Q17/04 , A61Q19/00 , A61Q19/10 , A61K2800/31 , A61K2800/33
摘要： The present disclosure relates generally to compositions for cosmetic or pharmaceutical application. The compositions include a carrier and rheology modulators.APP
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2.发明授权公开(公告)号：US11975099B2
公开(公告)日：2024-05-07
申请号：US17311354
申请日：2019-12-11
发明人： Shaohua Liu , Hanshu Zhang , Aijun Yang , Yiran Liu
摘要： The present invention relates to an ethanol foam sclerosing agent for vascular anomalies and a preparation method thereof. The ethanol foam sclerosing agent includes absolute ethanol, water, Tween 80 and a stabilizer. The ethanol foam sclerosing agent further includes hyaluronic acid. The mass composition of the ethanol foam sclerosing agent includes 32-42% of absolute ethanol, 0.5-2% of Tween 80, 0-25% (excluding 0) of egg yolk lecithin, 0-2% (excluding 0) of hyaluronic acid, and the balance of water. The stabilizer is hyaluronic acid or glycerin. Foam is prepared by the Tessari method. While the original therapeutic effect of ethanol is not changed, the side effect of the ethanol is significantly reduced.
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3.发明公开公开(公告)号：US20240024300A1
公开(公告)日：2024-01-25
申请号：US18353870
申请日：2023-07-17
发明人： David W. Osborne
摘要： A method for altering the PK profile of a pharmaceutical formulation containing a PDE-4 inhibitor, such as roflumilast, to reduce the spike in Cmax. The spike in Cmax is reduced by topically administering the PDE-4 inhibitor in combination with one or more phosphate ester surfactants. Reducing the spike in Cmax will reduce gastrointestinal side effects and result in better patient compliance.
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公开(公告)号：US20230346805A1
公开(公告)日：2023-11-02
申请号：US17597892
申请日：2020-07-30
发明人： Iain Stuart , Flor De Maria Alvarez Mitre , Russell Elliott , Gary Lawrence , Meital Cohen-Asis , Anat London-Drori , Yohan Hazot , Ariel Margulis
IPC分类号： A61K31/65 , A61K9/12 , A61K31/192 , A61K47/44 , A61K47/10 , A61P17/10 , A61K9/00 , A61K47/24 , A61K47/46 , A61Q19/00 , A61K8/02 , A61K8/04 , A61K8/92 , A61K8/34 , A61K8/36 , A61K8/42
CPC分类号： A61K31/65 , A61K9/122 , A61K31/192 , A61K47/44 , A61K47/10 , A61P17/10 , A61K9/0014 , A61K47/24 , A61K47/46 , A61Q19/00 , A61K8/0245 , A61K8/046 , A61K8/922 , A61K8/92 , A61K8/927 , A61K8/342 , A61K8/361 , A61K8/42 , A61K2800/651 , A61K2800/412
摘要： The present disclosure relates to compositions, including foamable compositions with improved properties, such as those comprising waxes, emollients, foam adjuvants and/or active agents, and methods for preparing and using them.
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公开(公告)号：US20230310820A1
公开(公告)日：2023-10-05
申请号：US18312217
申请日：2023-05-04
申请人： Frank Levy , Kimberley Levy
发明人： Frank Levy , Kimberley Levy
CPC分类号： A61M35/003 , A01N25/00 , A61K9/122 , A61M5/2053 , A61M13/003 , A61M35/00 , A61M37/00 , A61B2017/00893
摘要： A medical fluid suspension generating apparatus for performing medical procedures includes a Venturi-agitating tip assembly composed of a multi-channel arrangement at a proximal first end thereof and a tip at a distal second end thereof. The apparatus also includes a compressed medical fluid unit fluidly connected to the multi-channel arrangement at a proximal first end of the Venturi-agitating tip assembly and a medical solution fluidly connected to the multi-channel arrangement at a proximal first end of the Venturi-agitating tip assembly. Pressurized gas, from the compressed medical fluid unit, and the medical solution are combined within the Venturi-agitating tip assembly in a manner generating an enriched medical suspension that is ultimately dispensed from the suspension delivery apparatus.
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公开(公告)号：US20230233421A1
公开(公告)日：2023-07-27
申请号：US18126138
申请日：2023-03-24
发明人： Stephen BALDWIN , Scott CARPENTER , Heidi GRAHAM , Nanhye KIM , Tom MEYER , David Reynolds , Jerry Glen Vancleave , Eric DANN , Thomas DANN , Renee NELSON , Brian DANN
IPC分类号： A61K8/04 , A61K8/27 , A61Q17/04 , A61Q19/00 , A61K8/19 , A61Q7/00 , B65D83/14 , A61Q11/00 , A23P30/40 , A61K9/12 , A61Q5/06 , B65D83/20 , B65D83/62
CPC分类号： A61K8/046 , A61K8/27 , A61Q17/04 , A61Q19/00 , A61K8/19 , A61Q7/00 , B65D83/752 , A61Q11/00 , A61Q19/004 , A23P30/40 , A61K9/122 , A61Q5/06 , B65D83/207 , B65D83/62 , A61K2800/22 , A61K2800/87
摘要： The present disclosure relates to, inter alia, a formulation in a package, the formulation comprises one or more active agents and is co-mingled with a whipping agent prior to being filled under pressure into the package. The whipping agent is added in sufficient amounts to be dispersed in the formulation. The pressurized package is under sufficient pressure suitable to maintain the whipping agent dispersed in the formulation; and the pressurized package is under sufficient pressure to expel the formulation as a whipped formulation upon application of external force on the formulation in the package.
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公开(公告)号：US20190183797A1
公开(公告)日：2019-06-20
申请号：US16318805
申请日：2017-07-18
发明人： Rolf Daniels , Tobias Zahn
CPC分类号： A61K9/122 , A61K8/046 , A61K8/06 , A61K8/375 , A61K8/922 , A61K8/9789 , A61K9/0014 , A61K9/107 , A61K36/185 , A61K47/06 , A61K47/14 , A61K47/44 , A61P17/02 , A61P31/22 , A61Q19/00
摘要： The present disclosure relates to foams comprising outer birch bard extracts. Stable compositions thereof, as well as methods of producing such foams, and methods of using of such foams are also described herein. The foams of the present disclosure contain triterpenes, which are known to improve wound healing.
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公开(公告)号：US20180344640A1
公开(公告)日：2018-12-06
申请号：US16059720
申请日：2018-08-09
IPC分类号： A61K9/12 , A61K9/00 , A61K31/4164
CPC分类号： A61K9/122 , A61K9/0014 , A61K31/4164
摘要： The invention provides a water-based composition for treating an infection by a dermatophyte fungus comprising econazole or a pharmaceutically acceptable salt thereof. Also provided are methods of treatment utilizing the water-based foam composition, as well as its preparation.
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9.发明申请公开(公告)号：US20180264417A1
公开(公告)日：2018-09-20
申请号：US15982468
申请日：2018-05-17
CPC分类号： B01F3/04453 , A61B17/12109 , A61B17/12186 , A61K9/0019 , A61K9/122 , A61K47/02 , B01F7/1695 , B01F13/0033 , B01F13/0818 , B01F15/0206 , B01F15/0223 , B01F15/0225 , B01F15/0256 , B01F2003/04879 , B01F2003/04893 , B01F2003/04943 , B01F2215/0032
摘要： The present disclosure relates to a container for the production of a foamed sclerosant composition, to kits and systems including such a container, to methods for preparing a foamed sclerosant composition using such containers, and to foamed sclerosant compositions obtainable by such methods. In an aspect, the container comprises a sealed sterile container body having one or more sidewalls extending between a top and a bottom of the container body and defining a foaming space. The container further comprises a mixing element disposed in the container body. The container contains a previously introduced gas and liquid sclerosant composition. The mixing element is configured to be operatively coupled with a rotatable actuator without the actuator reaching the foaming space. A medical professional may select the appropriate quantity and concentration for every treatment.
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公开(公告)号：US20180235983A1
公开(公告)日：2018-08-23
申请号：US15552887
申请日：2016-02-25
摘要： The present invention relates to a method of preparing a nanoparticulate topical composition of a water soluble, water-susceptible active ingredient or its pharmaceutically acceptable salt, the method comprising steps of milling the water soluble, water-susceptible active ingredient or its salt, a wetting agent and a non-aqueous liquid vehicle to obtain a non-aqueous nanosuspension and converting the non-aqueous nanosuspension into a topical composition.
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