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    Optical implant and methods of implantation
    1.
    发明授权
    Optical implant and methods of implantation 有权

    公开(公告)号：US11980542B2

    公开(公告)日：2024-05-14

    申请号：US18118071

    申请日：2023-03-06

    申请人： Gholam Peyman

    发明人： Gholam Peyman ,  Lisa Brothers Arbisser

    IPC分类号： A61F2/16

    CPC分类号： A61F2/1648 ,  A61F2002/1681 ,  A61F2002/16965

    摘要： An apparatus has a central lens body for providing vision correction for a patient. The lens body has a central aperture and is configured as one of: a diffractive lens or a refractive lens. The lens body has at least one haptic extending from the lens body, and the central aperture has a form of a circular hole extending fully through the lens body when the apparatus is implanted in the eye. The lens body is formed from a substantially transparent material and the central aperture includes a darkened perimeter. The darkened perimeter of the central aperture includes a darkened internal wall extending through the lens body from an anterior surface to a posterior surface of the lens body.

    METHODS FOR TAILORING THE REFRACTIVE INDEX OF LENSES
    7.
    发明申请
    METHODS FOR TAILORING THE REFRACTIVE INDEX OF LENSES 审中-公开
    用于定制镜片折射率的方法

    公开(公告)号：US20160195735A1

    公开(公告)日：2016-07-07

    申请号：US15068396

    申请日：2016-03-11

    申请人： Battelle Memorial Institute

    发明人： Herbert S. Bresler ,  Erik Edwards ,  Amy M. Heintz ,  John S. Laudo ,  Alexander C. Morrow ,  Steven M. Risser

    IPC分类号： G02C7/02 ,  G02C7/04 ,  G02B1/04

    CPC分类号： G02C7/022 ,  A61F2/1627 ,  A61F2/1635 ,  A61F2/1659 ,  A61F2002/16965 ,  G02B1/043 ,  G02C7/04

    摘要： Methods and devices for altering the power of a lens, such as an intraocular lens, are disclosed. In one method, the lens comprises a single polymer matrix containing crosslinkable pendant groups, wherein the polymer matrix increases in volume when crosslinked. The lens does not contain free monomer. Upon exposure to ultraviolet radiation, crosslinking causes the exposed portion of the lens to increase in volume, causing an increase in the refractive index. In another method, the lens comprises a polymer matrix containing photobleachable chromophores. Upon exposure to ultraviolet radiation, photobleaching causes a decrease in refractive index in the exposed portion without any change in lens thickness. These methods avoid the need to wait for diffusion to occur to change the lens shape and avoid the need for a second exposure to radiation to lock in the changes to the lens.

    摘要翻译： 公开了用于改变诸如人工晶状体的透镜的功率的方法和装置。 在一种方法中，透镜包含含有可交联侧基的单一聚合物基质，其中当交联时聚合物基体的体积增加。 镜头不含有游离单体。 当暴露于紫外线辐射时，交联使得透镜的暴露部分体积增加，导致折射率增加。 在另一种方法中，透镜包含含有可光漂白的发色团的聚合物基质。 在紫外线照射下，光漂白导致曝光部分的折射率降低，透镜厚度没有变化。 这些方法避免了等待发生扩散以改变透镜形状的需要，并且避免了第二次暴露于辐射以锁定透镜变化的需要。

    STABLE POLYMERIZABLE UV-ABSORBING COLORANT FOR INTRAOCULAR LENS
    9.
    发明申请
    STABLE POLYMERIZABLE UV-ABSORBING COLORANT FOR INTRAOCULAR LENS 有权
    稳定的聚合紫外线吸收剂用于内窥镜

    公开(公告)号：US20150094439A1

    公开(公告)日：2015-04-02

    申请号：US14397352

    申请日：2013-04-30

    申请人： KOWA COMPANY, LTD.

    发明人： Masahiro Tamura ,  Takahide Oshita

    IPC分类号： C07C245/08 ,  A61L27/16 ,  C08F220/68

    CPC分类号： C07C245/08 ,  A61F2/16 ,  A61F2002/16965 ,  A61L27/16 ,  A61L27/50 ,  A61L2430/16 ,  C08F220/00 ,  C08F220/60 ,  C08F220/68 ,  C09B29/0003 ,  C09B29/12 ,  C09B69/106 ,  C08L33/26

    摘要： A polymerizable UV-absorbing colorant monomer is provided, which is excellent in stability under alkaline conditions and which is available for a useful material polymer for an intraocular lens. A compound, which is represented by the following general formula (1), is used as a polymerizable UV-absorbing monomer available for a material polymer for an intraocular lens: (in the general formula (1), R1 is a hydrogen atom, a hydroxy group, a carboxy group, an alkyl group having 1 to 8 carbon atoms, an alkoxy group having 1 to 8 carbon atoms, a sulfonic acid group, or a benzyloxy group, R2 is a hydrogen atom, a hydroxy group, or an alkoxy group having 1 to 4 carbon atoms, and R3 is represented by the following formula (2)): (in the general formula (2), R4 is a hydrogen atom or a methyl group, and R5 is a single bond or an alkylene group having 1 to 4 carbon atoms which may have a substituent or substituents.)

    摘要翻译： 提供了一种可聚合的UV吸收着色剂单体，其在碱性条件下的稳定性优异，并且可用于眼内透镜的有用材料聚合物。 使用由以下通式（1）表示的化合物作为可用于眼内透镜材料聚合物的可聚合的UV吸收单体：（在通式（1）中，R 1是氢原子， 羟基，羧基，碳原子数1〜8的烷基，碳原子数1〜8的烷氧基，磺酸基或苄氧基，R2是氢原子，羟基或烷氧基 具有1至4个碳原子的基团，R 3由下式（2）表示）：（在通式（2）中，R 4是氢原子或甲基，R 5是单键或亚烷基 具有1至4个可具有取代基的碳原子。）