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公开(公告)号：US12016333B2
公开(公告)日：2024-06-25
申请号：US17470055
申请日：2021-09-09
申请人： University of Florida Research Foundation, Inc. , Iowa State University Research Foundation, Inc.
发明人： Bryony C. Bonning , Mariah Kemmerer
IPC分类号： A01N37/46 , A01N25/06 , A01N63/00 , A01N63/50 , C07K14/005 , C07K14/015 , C07K14/435 , C12N7/00 , C12N15/85 , C12N15/86
CPC分类号： A01N37/46 , A01N25/06 , A01N63/00 , A01N63/50 , C07K14/005 , C07K14/015 , C07K14/43563 , C12N7/00 , C12N15/86 , C07K2319/55 , C12N2015/8518 , C12N2750/14022 , C12N2750/14031 , A01N63/50 , A01N63/14
摘要： A coat protein of Junonia coenia densovirus (JcDNV) is used to deliver attached peptide insect toxin across the gut epithelium of a fall armyworm, Spodoptera frugiperda. A fusion protein comprising VP4 attached to an insect toxin via a peptide linker is developed. A composition comprising a JcDNV coat protein attached to an insect toxin via a peptide linker can be used for insect pest control.
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公开(公告)号：US20240150747A1
公开(公告)日：2024-05-09
申请号：US18281486
申请日：2021-03-17
摘要： The present disclosure relates to compositions and methods for inducing encystment of and/or stabilising ciliate cells. In particular, the present disclosure relates to polymers and polymeric solutions, including hydrocolloids, which may be used to induce encystment of trophont ciliate cells to form encysted ciliate cells and/or stabilise encysted cells. The present disclosure also relates to methods of infecting and/or colonising molluscs with the compositions and ciliates described herein.
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公开(公告)号：US11918631B2
公开(公告)日：2024-03-05
申请号：US15159929
申请日：2016-05-20
发明人： David Bikard , Luciano Marraffini
IPC分类号： A61K38/46 , A01N63/00 , A61K31/7105 , A61K31/713 , A61K45/06 , C12N9/16 , C12N9/22 , C12N15/113 , C12N15/74
CPC分类号： A61K38/465 , A01N63/00 , A61K31/7105 , A61K31/713 , A61K45/06 , C12N9/16 , C12N9/22 , C12N15/113 , C12N15/74 , C12Y301/00 , C12N2310/10 , C12N2310/20 , C12N2795/10331 , C12N2795/10332 , C12N2795/10343 , C12N2795/10371 , A61K31/7105 , A61K2300/00 , A61K31/713 , A61K2300/00
摘要： Provided are compositions and methods for selectively reducing the amount of antibiotic resistant and/or virulent bacteria in a mixed bacteria population, or for reducing any other type of unwanted bacteria in a mixed bacteria population. The compositions and methods involve targeting bacteria that are differentiated from other members of the population by at least one unique clustered regularly interspaced short palindromic repeats (CRISPR) targeted DNA sequence. The compositions and methods can be readily adapted to target any bacteria or any bacteria plasmid, or both.
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公开(公告)号：US11844760B2
公开(公告)日：2023-12-19
申请号：US16813615
申请日：2020-03-09
IPC分类号： A01N63/00 , A61K31/7105 , C12N15/113 , C12N15/74 , C12N15/70 , A61K31/711 , A61K45/06 , C12N15/10 , C12N9/16 , A61K35/74 , C12N15/90 , A01N63/50 , A01N63/60 , A61K48/00 , C12N1/20 , C12N7/00 , A61K35/00
CPC分类号： A61K31/7105 , A01N63/00 , A01N63/50 , A01N63/60 , A61K31/711 , A61K35/74 , A61K45/06 , A61K48/005 , C12N1/20 , C12N7/00 , C12N9/16 , C12N15/102 , C12N15/113 , C12N15/70 , C12N15/746 , C12N15/902 , A61K2035/11 , A61K2300/00 , C12N2310/20 , C12N2320/31 , C12N2795/00032 , C12N2795/10132 , Y02A50/30 , A61K31/7105 , A61K2300/00 , A61K31/711 , A61K2300/00 , A01N63/60 , A01N63/20 , A01N63/50 , A01N63/60
摘要： The invention relates to methods, uses, systems, arrays, engineered nucleotide sequences and vectors for inhibiting bacterial population growth or for altering the relative ratio of sub-populations of first and second bacteria in a mixed population of bacteria. The invention is particularly useful, for example, for treatment of microbes such as for environmental, medical, food and beverage use. The invention relates inter alia to methods of controlling microbiologically influenced corrosion (MIC) or biofouling of a substrate or fluid in an industrial or domestic system.
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公开(公告)号：US11751572B2
公开(公告)日：2023-09-12
申请号：US17379979
申请日：2021-07-19
CPC分类号： A01N63/00
摘要： The present disclosure provides a method of increasing aggregation in a soil comprising the step of administering to the soil an amount of a microalgae material to increase aggregation in the soil compared to a substantially identical untreated soil, wherein the microalgae material comprises Chlorella cells and/or Schizochytrium cells. Also disclosed is a method of enhancing the active carbon score of a soil, comprising administering an amount of a microalgae material to the soil to increase the active carbon score of the soil compared to a substantially identical untreated soil, wherein the microalgae material comprises Chlorella cells and/or Schizochytrium cells.
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公开(公告)号：US11702665B2
公开(公告)日：2023-07-18
申请号：US17217952
申请日：2021-03-30
发明人： Damian Curtis , Benjamin L. Golomb , Dilara Ally , Florencia A. Ficarra , Rauf Salamzade , Bjorn A. Traag
IPC分类号： C12N15/74 , C12N9/04 , C07K14/325 , C12N9/24 , C12N9/42 , C07K14/195 , C12N11/16 , C12N15/62 , C12N1/20 , C12N15/10 , A01N63/50 , A01N63/10 , A01N63/00
CPC分类号： C12N15/74 , A01N63/00 , A01N63/10 , A01N63/50 , C07K14/195 , C07K14/325 , C12N1/20 , C12N9/0006 , C12N9/24 , C12N9/2442 , C12N11/16 , C12N15/1037 , C12N15/625 , C12Y101/01004 , C12Y302/01014 , C07K2319/035 , A01N63/50 , A01N37/46 , A01N63/25 , A01N63/00 , A01N37/46 , A01N63/10
摘要： Signal sequences useful for targeting proteins and peptides to the surface of endospores produced by Paenibacillus family members and methods of using the same are provided. The display of heterologous molecules, such as peptides, polypeptides and other recombinant constructs, on the spore surface of Paenibacillus family members, using particular N-terminal targeting sequences and derivatives of the same, are also provided.
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8.发明公开公开(公告)号：US20230217931A1
公开(公告)日：2023-07-13
申请号：US17784013
申请日：2020-12-21
申请人： Institut national de recherche pour l’agriculture, l’alimentation et l’environnement , INSTITUT NATIONAL SUPERIEUR DES SCIENCES AGRONOMIQUES, AGROALIMENTAIRES, HORTICOLES ET DU PAYSAGE , UNIVERSITE D'ANGERS
发明人： Bruno LE CAM , Valerie CAFFIER
摘要： The present invention relates to a bio-control method for combating the propagation of phytopathogenic fungi or oomycetes on plants, comprising the application, to the soil and/or to the vegetative apparatus of plants that are infected or are capable of being infected by pathogenic endemic fungal or oomycete strains referred to as type A, of a composition comprising a mixture of at least two strains, referred to as type B, of the same species, said type B strains being non-pathogenic for said plant, sexually compatible with said pathogenic type A strains and characterized in that they exhibit: a) sexual reproduction, b) a sexual phase initiated in non-parasitic mode, c) reproduction according to a heterothallic mode, and d) the existence of special forms or divergent populations within the species, capable of producing, by crossing with the type A strains, descendants that are non-pathogenic or even sterile on said plant of interest, and characterized in that the mixture of non-pathogenic type B strains comprises strains of opposite mating-type signs.
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公开(公告)号：US20190248715A1
公开(公告)日：2019-08-15
申请号：US16161012
申请日：2018-10-15
摘要： The present invention relates to increasing and/or maintaining nitrogen content in soil by administration of granular or powdered nitrification inhibitors coated with urease inhibitors. In one embodiment, urease inhibitors are dispersed in an improved organo liquid delivery system at concentration levels of 50-90%. In another embodiment, urease inhibitors were applied in a non-aqueous, organo liquid delivery system coating solid nitrification inhibitors utilizing simple blending equipment at temperatures of 20°-70° C. Another embodiment discloses a dry, flowable additive containing a nitrification inhibitor coated with a urease inhibitor which can be administered directly to the soil, to a dry natural and/or a manmade fertilizer or to a liquid fertilizer which provides for the reduction of nitrogen loss from the soil.
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10.发明申请公开(公告)号：US20190216091A1
公开(公告)日：2019-07-18
申请号：US16366816
申请日：2019-03-27
申请人： FMC Corporation
摘要： Compositions and methods for application to plants are provided for a new strain of Bacillus licheniformis RTI184 having plant growth promoting activity. Compositions and extracts of Bacillus licheniformis strains that include newly identified Fengycin-like and Dehydroxyfengycin-like cyclic lipopeptides designated as “Fengycin MB-Cit” and “Dehydroxyfengycin MB-Cit”, respectively, are also provided. In particular aspects, compositions containing the Bacillus licheniformis strain RTI184 can be applied alone or in combination with chemical agents or other microbial agents to benefit plant growth.
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