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公开(公告)号：US11905615B2
公开(公告)日：2024-02-20
申请号：US17808432
申请日：2022-06-23
发明人： Hong Xu
IPC分类号： C25D7/00 , B41J2/16 , C25D5/02 , C25D5/10 , C25D1/00 , C25D5/00 , A61M11/00 , C25D5/54 , B05B17/00 , C25D3/38 , C25D3/46 , C25D3/48 , C25D3/54 , C25D5/34 , C25D5/48
CPC分类号： C25D7/00 , A61M11/005 , B05B17/0646 , B41J2/162 , B41J2/1625 , B41J2/1629 , B41J2/1631 , C25D1/003 , C25D3/38 , C25D3/46 , C25D3/48 , C25D3/54 , C25D5/022 , C25D5/10 , C25D5/34 , C25D5/48 , C25D5/54 , C25D5/611
摘要： In one embodiment, a method for manufacturing an aperture plate includes depositing a releasable seed layer above a substrate, applying a first patterned photolithography mask above the releasable seed layer, the first patterned photolithography mask having a negative pattern to a desired aperture pattern, electroplating a first material above the exposed portions of the releasable seed layer and defined by the first mask, applying a second photolithography mask above the first material, the second photolithography mask having a negative pattern to a first cavity, electroplating a second material above the exposed portions of the first material and defined by the second mask, removing both masks, and etching the releasable seed layer to release the first material and the second material. The first and second material form an aperture plate for use in aerosolizing a liquid. Other aperture plates and methods of producing aperture plates are described according to other embodiments.
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公开(公告)号：US20230321368A1
公开(公告)日：2023-10-12
申请号：US17818549
申请日：2022-08-09
发明人： Patrick POWER
CPC分类号： A61M11/02 , A61M11/00 , A61M16/024 , A61M16/16 , A61M16/161 , A61M11/06
摘要： An aerosol delivery system has a nebulizer and a humidifier providing a gas flow to the nebulizer. A controller varies humidity level of the gas flow to the nebulizer so that if the nebulizer is not operating it has about 100% humidity and it is operating the value is less to allow for the humidification effect of the nebulizer. The control may be achieved by dynamically varying proportions of flow through a dry branch and a humidification branch.
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公开(公告)号：US11672939B2
公开(公告)日：2023-06-13
申请号：US16749024
申请日：2020-01-22
IPC分类号： A61M16/00 , A61M16/14 , A61M15/00 , A61M11/00 , A61M16/06 , A61M16/08 , A61M16/16 , B05B12/08 , B05B17/00 , B05B17/06
CPC分类号： A61M16/14 , A61M11/002 , A61M11/003 , A61M11/005 , A61M15/0085 , A61M16/0057 , A61M16/0666 , A61M16/0672 , A61M16/0833 , A61M16/0875 , A61M16/147 , A61M16/16 , A61M16/0808 , A61M2202/0208 , A61M2206/14 , B05B12/081 , B05B17/0646 , B05B17/0669
摘要： A supplemental oxygen delivery system is described in which Aerosol is delivered into a housing 10, 20, which sits in the circuit from the supplemental oxygen supply and optional humidifier. The supplemental oxygen passes through this chamber 10, 20 in which the aerosol is located, and collects the aerosol transporting it to a patient via a nasal cannula 3 or a face mask 4. An aerosol generator 9 is mounted to the housing 10, 20 and delivers aerosol into an oxygen stream 13 flowing between an inlet 14 and an outlet 15 of the housing 10. The housing 10 also has a removable plug 16 in the base 17 thereof for draining any liquid that accumulates in the housing 10. There is no disruption of oxygen delivery to patients using nasal cannulas who currently have to use a separate face-mask when receiving nebulized medication.
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公开(公告)号：US11654448B2
公开(公告)日：2023-05-23
申请号：US16756204
申请日：2018-11-27
发明人： Michael Aherne , Colga Coye , Philip Scanlon
CPC分类号： B05B17/0646
摘要： An aperture plate (1) is attached at its rim (203) to a support washer (3) by adhesive. Anchor grooves (204) having a zig-zag pattern in plan are machined in the lower surface of the rim (203 of the aperture plate before application of the adhesive. The grooves (204) extend out to the edge of the aperture plate (1). The anchor grooves have a depth in the range of 10 μm to 40 μm, and a width in the range of 20 μm to 150 μm, and an angular pitch in the range of 2.5° to 12.5°. Excellent bonding strength is achieved for long term reliable attachment in an environment of high frequency vibration and moisture and chemical corrosion.
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公开(公告)号：US20230044607A1
公开(公告)日：2023-02-09
申请号：US17888334
申请日：2022-08-15
发明人： Brendan HOGAN , Kieran HYLAND , Anthony REDMOND
摘要： An aerosol generator with electrical power conducting pins has a vibratable plate with apertures therein and an annular piezo. An annular support member supports the piezo and the vibratable plate. A first electrical power conducting pin engages directly with a first, top, surface of the piezo. A second electrical power conducting pin indirectly conducts electrical power to a second surface of the piezo, by contacting an extension tab. There is a film of cured epoxy adhesive on the tab. The aerosol generator avoids need for soldered joints for electrical contact, and the pins are conveniently mounted parallel to each on the same lateral and top side of the piezo and support member. The pins may have multi-point tips for particularly effective electrical contact.
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公开(公告)号：US11534559B2
公开(公告)日：2022-12-27
申请号：US16118668
申请日：2018-08-31
摘要： A system for delivery of aerosol therapy to spontaneously breathing patients comprises a housing which defines a chamber. The housing has a base, a top and a main body extending between the base and the top. An ambient air inlet is located adjacent to the base and is normally closed by an inlet valve. The housing also has a patient port for receiving a mouthpiece or a face mask. The mouthpiece has an exhaust outlet closed by an exhaust valve. Similarly, the face mask has an exhaust outlet closed by an exhaust valve. Exhaled air is exhausted through the valves and to prevent recirculation through the chamber which would adversely affect dose efficiencies. The housing also has an aerosol port for receiving a vibrating mesh aerosol generating device. The aerosol port is located in a side of the main body of the housing for delivery of aerosol into the chamber between the inlet valve and the patient port. A boss extends upwardly from the base and is spaced-apart inwardly of the main body of the housing to define a reception space or well.
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公开(公告)号：US11446695B2
公开(公告)日：2022-09-20
申请号：US17227559
申请日：2021-04-12
发明人： Brendan Hogan , Kieran Hyland , Anthony Redmond
摘要： An aerosol generator has a vibratable plate with apertures therein and an annular piezo which causes movement of the vibratable plate. An annular support member supports the piezo and the vibratable plate. A first electrical power conducting pin engages directly with a first, top, surface of the piezo. A second electrical power conducting pin indirectly conducts electrical power to a second surface of the piezo, by contacting an extension tab of the support member, also on its top side. There is a film of cured epoxy adhesive on the tab, providing excellent gripping force between the pin and the support. The aerosol generator avoids need for soldered joints for electrical contact, and the pins are conveniently mounted parallel to each on the same lateral and top side of the piezo and support member. The pins may have multi-point tips for particularly effective electrical contact.
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公开(公告)号：US11440030B2
公开(公告)日：2022-09-13
申请号：US16358338
申请日：2019-03-19
发明人： Brendan Hogan , Hong Xu
摘要： An aperture plate is manufactured by plating metal around a mask of resist columns having a desired size, pitch, and profile, which yields a wafer about 60 μm thickness. This is approximately the full desired target aperture plate thickness. The plating is continued so that the metal overlies the top surfaces of the columns until the desired apertures are achieved. This needs only one masking/plating cycle to achieve the desired plate thickness. Also, the plate has passageways formed beneath the apertures, formed as an integral part of the method, by mask material removal. These are suitable for entrainment of aerosolized droplets exiting the apertures.
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公开(公告)号：US20210252231A1
公开(公告)日：2021-08-19
申请号：US17307057
申请日：2021-05-04
发明人： Michael CASEY , Joseph Grehan , Kieran Hyland , John Power
摘要： A nebulizer comprises a controller linked at its output to a nebulizer head, and at its input to a USB cable and USB plug for connection to a host system. The link between the USB plug and the controller is a USB cable with power and data channels. The controller comprises a boost circuit, a microcontroller 11, and a drive circuit. The latter provides power and control signals via a cable and proprietary plug to the nebulizer head. These signals provide power and control for a vibrating membrane receiving a liquid to be aerosolised. The controller has a housing with LED status lamps, and an ON/OFF button. The controller can be controlled via a host, either locally or remotely.
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公开(公告)号：US20200246558A1
公开(公告)日：2020-08-06
申请号：US16857701
申请日：2020-04-24
摘要： A system for delivery of aerosol therapy to spontaneously breathing patients comprises a housing which defines a chamber. The housing has a base, a top and a main body extending between the base and the top. An ambient air inlet is located adjacent to the base and is normally closed by an inlet valve. The housing also has a patient port for receiving a mouthpiece or a face mask. The mouthpiece has an exhaust outlet closed by an exhaust valve. Similarly, the face mask has an exhaust outlet closed by an exhaust valve. Exhaled air is exhausted through the valves and to prevent recirculation through the chamber which would adversely affect dose efficiencies. The housing also has an aerosol port for receiving a vibrating mesh aerosol generating device. The aerosol port is located in a side of the main body of the housing for delivery of aerosol into the chamber between the inlet valve and the patient port. A boss extends upwardly from the base and is spaced-apart inwardly of the main body of the housing to define a reception space or well.
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