摘要:
An embodiment of the invention is directed to a bone marrow aspiration device comprising a plurality of syringes, each of which operates in a series of sequential steps to obtain bone marrow of high quality and therapeutic value, i.e., having a high mesenchymal stem cell (“MSC”) MSC/ml number. In certain embodiments, a syringe may be used along with a collection vessel or with a second syringe. A further embodiment of the invention is directed to a method for using the bone marrow aspiration device as set forth herein.
摘要:
A system and method for isolating and separating lipoaspirate particles. The system includes a generally cylindrical container having a lid and a bottom wherein the container includes at least one input port positioned to permit a lipoaspirate fluid to enter the container above the bottom; and a source of a vacuum coupled to the container to provide a partial vacuum during use of the system.
摘要:
The claimed invention is directed to a spinal fusion device comprising a load-bearing interbody component configured to fit between two adjacent vertebrae, wherein the interbody component comprises one or more openings to allow access to the vertebrae, a retention component that is configured to at least partially close the one or more openings of the interbody component and one or more fasteners that are coupled to the retention component to compress the two adjacent vertebrae to the interbody component, and methods of using a spinal fusion device.
摘要:
Embodiments of the invention is directed to methods of forming a bone-like material, by placing a matrix into a culture container, adding cells to the matrix, placing the tissue-cell construct into the culturing environment and incubating the construct under appropriate conditions for the time required to produce an amount of bone-like material of sufficient volume to be harvested for further processing. Other embodiments of the invention are directed to the use of the bone-like material formed by methods of the invention in implantation procedures.
摘要:
A composite bone graft which comprises an allograft bone component; a synthetic bone substitute, wherein the synthetic bone substitute is in contact with the allograft bone component. The composite is arranged within a resorbable mesh casing.
摘要:
The invention is directed to an anchor for fixing a tendon or a ligament in a bone comprising: an elongated tubular body having a bore extending along a longitudinal axis, said tubular body comprising first and second independent parts slidably contacting each other, the first and second independent parts each having an outer circumferential surface along a length thereof parallel to the longitudinal axis, and each having an elongated partial inner bore, such that the tubular body is capable of mounting a tendon or ligament within the partial inner bore.
摘要:
The invention is directed to a method for isolating stromal cells to form a therapeutic composition; and administering said therapeutic composition to the subject. A further embodiment of the invention is directed to therapeutic compositions comprising isolated stromal cells.
摘要:
The invention is directed to an interbody fusion device comprises a fusion bearing device and a retention device and further comprises two bone screws that pass through the retention device and into the vertebral bodies. When implanted, the construct is flush with the anterior face of the vertebras and provides support and temporary fixation for the ultimate fusion of the vertebral bodies.
摘要:
The invention comprises a combination of biological elements that will naturally remodel in vivo based on applied mechanical forces. The final composition will possess mechanical properties similar to cartilage or a disc, and significantly less stiff than bone or implants comprised of metals or plastics. The equilibrium stress conduction will minimize unnatural forces on neighboring healthy discs.
摘要:
A method and apparatus is provided for use in spinal fusion procedures. An interbody fusion device has a first piece that is a load bearing device designed to bear the axial loading from the end plates of adjacent vertebrae. A second piece of the interbody fusion device is a retention component whose primary functions are to prevent migration of the load bearing device and loss or migration of graft material from within the load bearing device. A secondary function of the retention component is to address fixation of fasteners when the surgeon is confronted with a challenging access to adequate boney structures due to excessive curvature/angulation of the vertebrae column, minimal invasive surgery techniques, danger to surrounding vascular or neurological tissues, poor bone quality, or similar surgical complications. A tertiary function of the retention component is to provide better alignment and stabilization of misaligned vertebrae when spondylolisthesis is a significant factor. One or more fasteners secure the retention component to each of the vertebrae above and below the load bearing device. The fasteners cause the end plates of the vertebrae to compress the end plates to the load bearing device to facilitate proper fusion.