摘要:
A strong, porous article useful as a bone substitute material. The article comprises a continuous strong framework structure having struts defining interstices which interconnect throughout the bulk volume, and may have ceramic or osteoconductive material occupying at least a portion of the same bulk volume as the framework structure. Either as a coating on the strong framework struts or between the framework struts and the ceramic or osteoconductive—osteoinductive materials is a resilient material which serves to distribute stresses within the article.
摘要:
A strong, porous article useful as a bone substitute material and having an outer surface defining a shape having a bulk volume and having open interconnecting interstices extending throughout said volume and opening through said surface. The article comprises a continuous strong framework structure having interstices which interconnect throughout the bulk volume and a second continuous material occupying at least a portion of the same bulk volume as the framework structure. The second material comprises an osteoinductive and/or osteoconductive composition. This composition may be present in one of several forms. One of these is as a coating on the surface of the framework structure. A second form is in the form of a composite, intimately mixed with the framework material within the framework struts. The third form is as a porous mass within the interstices of the framework structure, having pores which are interconnecting with themselves, and with the interstices of the framework structure. Desirably, the porous osteoinductive or osteoconductive composition extends throughout said bulk volume. In a preferred embodiment, the framework structure is formed of a ceramic material. In a further embodiment, the framework structure may be further structurally reinforced with a dense material component integrally affixed thereto.
摘要:
A strong, porous article useful as a bone substitute material. The article comprises a continuous strong framework structure having struts defining interstices which interconnect throughout the bulk volume, and may have ceramic or osteoconductive material occupying at least a portion of the same bulk volume as the framework structure. Either as a coating on the strong framework struts or between the framework struts and the ceramic or osteoconductive-osteoinductive materials is a resilient material which serves to distribute stresses within the article.
摘要:
A method for forming a ceramic article useful as a bone substitute and having an outer surface defining a shape having a bulk volume and having open, interconnecting openings extending throughout the volume and opening through the surface, includes, providing an organic open-pore structure, coating surface of pores of the structure with a ceramic slip, pyrolyzing the organic structure to leave a ceramic structure having struts defining a plurality of interconnecting interstices, and providing within the interstices a porous osteoconductive composition exposed to the interconnecting openings. In a preferred embodiment, the ceramic slip includes a strong, supportive ceramic material and a separate osteoconductive material.
摘要:
A process for producing a rigid reticulated article involves coating a reticulated substrate which has open, interconnected porosity with a first dispersion comprising a ceramic or metal powder to form a first coating thereon; drying the coated reticulated substrate; contacting the coated reticulated substrate with one or more additional dispersions in succession to form one or more additional coatings thereon; drying the additional coatings between the steps of contacting; heating the coated reticulated substrate to pyrolyze organic components; and sintering the coated reticulated substrate to form a reticulated article, wherein each dispersion has a viscosity less than that of all preceding dispersions. A rigid reticulated article includes inner, intermediate and outer sintered layers of material in which the inner and outer layers are of different composition and the intermediate layer is a composite of the inner and outer layers.
摘要:
Instrument for creating voids and channels in bone; and for obtaining samples of bone tissue. The instruments are suitable for reducing fractures in bone and for compacting the bone to create a barrier for leakage upon material injection. The instruments may also be used for bone biopsy and for obtaining samples of bone tissue. Methods for using these instruments are also disclosed.
摘要:
A portable electrical device charging system and method for using thermal energy, especially for use in the field or as part of military operations, is disclosed. The inventive electrical device charging system has one or more thermal electric generators attached, physically connected to, or incorporated within a container or pouch that is used to heat packaged meals-ready-to-eat (“MRE”). With the generation of heat to cook the MRE, the heat transfer through the container or pouch activates the thermal electric generators which generates electricity, in the form of an electric current, that can be used to charge any electrical device including an electrical storage device. More particularly, the generated electrical current may be used to charge radios, batteries, cell phones, personal data assistant devices, tablets, cameras, flashlights, or any other similar device.
摘要:
An apparatus for the delivery of a biological composite and a method, kit, and system for preparing a biological composite is described herein. The biological composite includes both inorganic and biological materials.
摘要:
Biologically active composites containing calcium phosphate, more specifically beta-tri-calcium phosphate, and methods of preparing the same are disclosed herein. Also disclosed are methods of restoring an osseous void and complimentary kits for the disclosed composites.
摘要:
An apparatus for the delivery of a biological composite and a method, kit, and system for preparing a biological composite is described herein. The biological composite includes both inorganic and biological materials.