Abstract:
The present invention relates to a composition comprising embryonic stem cells or haematopoietic stem cells or precursor cells being obtained by differentiation of said embryonic stem cells as well as trophoblasts, trophoblasts precursor and/or placental cell derived from said trophopblasts, all cell types being derived from the same embryonic stem cell origin. Further, the present invention relates to the induction of immune tolerance in an Individual as well as methods for cell, tissue and organ transplantation. The composition according to the present invention may be used in the treatment or therapy of transplantation or gene therapy or in the field of tissue engineering.
Abstract:
The invention relates to the production of adult dedifferentiated, programmable stem cells from human monocytes by cultivation of monocytes in a culture medium which contains M-CSF and IL-3. The invention further relates to pharmaceutical preparations, which contain the dedifferentiated, programmable stem cells and the use of these stem cells for the production of target cells and target tissue.
Abstract:
The invention relates to the production of adult dedifferentiated, programmable stem cells from human monocytes by cultivation of monocytes in a culture medium which contains M-CSF and IL-3. The invention further relates to pharmaceutical preparations, which contain the dedifferentiated, programmable stem cells and the use of these stem cells for the production of target cells and target tissue.
Abstract:
Apparatus and method for harvesting seed bearing cones from a tree, the apparatus having a retrieving structure and holding structure to define a collecting enclosure therebetween to receive cone bearing material with structure to unload the collecting enclosure. The apparatus has a guide to encircle the tree to ensure generally axial movement, and separating structure adjacent an upper portion thereof which separates cone containing material from the tree resulting from upwards movement of the apparatus. In one embodiment the separating structure has a plurality of recesses to receive the tree trunk, the recesses being provided with knives which cut the branches when the trunk enters the recess and the device is moved upwardly up the trunk. Alternatively, the separating structure has recesses to receive branches and is provided with rake means to rake the cones from the branches. The method includes lowering of the apparatus generally axially down the tree and shifting the apparatus generally laterally to engage a portion of the tree within one of the recesses. Apparatus is moved axially upwardly so that edges of the recesses remove cone containing material from the tree.
Abstract:
The invention relates to the production of adult dedifferentiated, programmable stem cells from human monocytes by cultivation of monocytes in a culture medium which contains M-CSF and IL-3. The invention further relates to pharmaceutical preparations, which contain the dedifferentiated, programmable stem cells and the use of these stem cells for the production of target cells and target tissue.
Abstract:
The invention relates to cells of monocytic origin suitable for the prevention and/or treatment of diseases associated with disturbed self-tolerance, in particular autoimmune diseases and allergies, and to pharmaceutical preparations containing these cells. The cells are autologous in relation to the patient to whom they are to be administered. The invention further relates to a process for the generation and/or, propagation of autologous regulatory T cells.
Abstract:
The invention relates to the production of adult dedifferentiated, programmable stem cells from human monocytes by cultivation of monocytes in a culture medium which contains M-CSF and IL-3. The invention further relates to pharmaceutical preparations, which contain the dedifferentiated, programmable stem cells and the use of these stem cells for the production of target cells and target tissue.
Abstract:
The invention relates to the production of adult dedifferentiated, programmable stem cells from human monocytes by cultivation of monocytes in a culture medium which contains M-CSF and IL-3. The invention further relates to pharmaceutical preparations, which contain the dedifferentiated, programmable stem cells and the use of these stem cells for the production of target cells and target tissue.
Abstract:
The invention relates to transplant acceptance inducing cells of monocytic origin, their production as well as their use for generating transplant acceptance. The invention also relates to the monoclonal antibody GM-7, which specifically recognises human transplant acceptance inducing cells of the invention. The invention further relates to the use of the antibody GM-7 for detection and/or selection transplant-acceptance inducing cells.
Abstract:
The invention relates to the production of adult dedifferentiated, programmable stem cells from human monocytes by cultivation of monocytes in a culture medium which contains M-CSF and IL-3. The invention further relates to pharmaceutical preparations, which contain the dedifferentiated, programmable stem cells and the use of these stem cells for the production of target cells and target tissue.