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公开(公告)号：US20210348204A1
公开(公告)日：2021-11-11
申请号：US17285800
申请日：2019-10-16
Applicant: Trait Biosciences, Inc.
Inventor： Richard T. Sayre , Elton Carvalho Goncalves , Jennifer Stamps , Tawanda Zidenga , Stephanie Willette
Abstract: The current inventive technology includes novel systems, methods and compositions for the in vivo production, modification and isolation of terpene compounds from Cannabis or other plants. In particular, the invention provides systems and methods for high level in vivo biosynthesis of water-soluble terpene compounds. In one preferred embodiment, the present invention generally relates to the conversion of Cannabis sativa or hemp derived terpenes into water-soluble terpene compounds, such as terpene glycosides, glycosylated-xylosylated terpenes, and an acetylated glycoside terpenes. In one preferred aspect, the invention may include system for producing water-soluble terpene compounds in yeast and tobacco cell suspension cultures, as well as an in planta system using transgenic Cannabis or hemp plants.
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公开(公告)号：US20190316144A1
公开(公告)日：2019-10-17
申请号：US16426059
申请日：2019-05-30
Applicant: Trait Biosciences Inc.
Inventor： Richard T. Sayre , Elton Carvalho Gonçalves , Tawanda Zidenga , Stephanie Willette
IPC: C12N15/82 , C12N9/10 , A61K31/352 , C12N9/02
Abstract: The present invention includes systems, methods and compositions for the in vivo bioconversion of water-soluble cannabinoids in plant cell suspension cultures.
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公开(公告)号：US11946059B2
公开(公告)日：2024-04-02
申请号：US16426059
申请日：2019-05-30
Applicant: Trait Biosciences Inc.
Inventor： Richard T. Sayre , Elton Carvalho Gonçalves , Tawanda Zidenga , Stephanie Willette
IPC: C12N15/82 , A61K31/352 , C12N9/02 , C12N9/10
CPC classification number: C12N15/8257 , A61K31/352 , C12N9/0042 , C12N9/1051 , C12N15/8201 , C12Y106/02004 , C12Y204/01
Abstract: The present invention includes systems, methods and compositions for the in vivo bioconversion of water-soluble cannabinoids in plant cell suspension cultures.
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公开(公告)号：US20240301449A1
公开(公告)日：2024-09-12
申请号：US18430133
申请日：2024-02-01
Applicant: Trait Biosciences Inc.
Inventor： Richard T. Sayre , Elton Carvalho Gonçalves , Tawanda Zidenga , Stephanie Willette
IPC: C12P7/22 , A61K9/00 , A61K31/352 , A61K36/81 , C12P19/18
CPC classification number: C12P7/22 , A61K9/0056 , A61K31/352 , A61K36/81 , C12P19/18
Abstract: The present invention includes systems, methods and compositions for the in vivo bioconversion of water-soluble cannabinoid glycosides in cell cultures.
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Patent Agency Ranking
公开(公告)号：US11905543B2
公开(公告)日：2024-02-20
申请号：US16425654
申请日：2019-05-29
Applicant: Trait Biosciences Inc.
Inventor： Richard T. Sayre , Elton Carvalho Gonçalves , Tawanda Zidenga , Stephanie Willette
IPC: C12P7/22 , A61K9/00 , C12P19/18 , A61K31/352 , A61K36/81
CPC classification number: C12P7/22 , A61K9/0056 , A61K31/352 , A61K36/81 , C12P19/18
Abstract: The present invention includes systems, methods and compositions for the in vivo bioconversion of water-soluble acetylated cannabinoid glycosides in plant cell suspension cultures.
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6.发明申请公开(公告)号：US20200046639A1
公开(公告)日：2020-02-13
申请号：US16425744
申请日：2019-05-29
Applicant: Trait Biosciences Inc.
Inventor： Richard T. Sayre , Elton Carvalho Gonçalves , Tawanda Zidenga , Stephanie Willette
IPC: A61K9/00 , A61K31/7034 , A61K9/08 , A61K47/36 , A61K47/26 , A23L33/105 , A23L33/125 , C12G3/04
Abstract: The present invention includes systems, methods and compositions related to the production and use of chemically modified cannabinoid food and beverage additives having enhanced water solubility and stability.
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公开(公告)号：US20240207179A1
公开(公告)日：2024-06-27
申请号：US18364273
申请日：2023-08-02
Applicant: Trait Biosciences Inc.
Inventor： Richard T. Sayre , Elton Carvalho Gonçalves , Tawanda Zidenga , Stephanie Willette
IPC: A61K9/00 , A23L33/105 , A23L33/125 , A61K9/08 , A61K31/7034 , A61K47/26 , A61K47/36 , C12G3/04
CPC classification number: A61K9/0095 , A23L33/105 , A23L33/125 , A61K9/08 , A61K31/7034 , A61K47/26 , A61K47/36 , C12G3/04 , A23V2002/00
Abstract: The present invention includes systems, methods and compositions related to the production and use of chemically modified cannabinoid food and beverage additives having enhanced water solubility and stability.
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公开(公告)号：US20220267820A1
公开(公告)日：2022-08-25
申请号：US17189063
申请日：2021-03-01
Applicant: Trait Biosciences, Inc.
Inventor： Richard T. Sayre , Elton Carvalho Goncalves , Tawanda Zidenga , Stephanie Willette , Timothy Travers , Erick Lebrun
Abstract: The present invention relates generally to the use of novel UDP-glucosyltransferases enzymes having specific activity towards cannabinoid compounds. The present invention further relates generally to the use of novel UGT enzymes having specific activity towards cannabinoid compounds to generate water-soluble cannabinoid glycoside compounds.
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9.发明申请公开(公告)号：US20190382807A1
公开(公告)日：2019-12-19
申请号：US16425654
申请日：2019-05-29
Applicant: Trait Biosciences Inc.
Inventor： Richard T. Sayre , Elton Carvalho Gonçalves , Tawanda Zidenga , Stephanie Willette
IPC: C12P7/22 , A61K36/81 , A61K31/352 , A61K9/00
Abstract: The present invention includes systems, methods and compositions for the in vivo bioconversion of water-soluble acetylated cannabinoid glycosides in plant cell suspension cultures.
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