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公开(公告)号：US20210348204A1
公开(公告)日：2021-11-11
申请号：US17285800
申请日：2019-10-16
Applicant: Trait Biosciences, Inc.
Inventor： Richard T. Sayre , Elton Carvalho Goncalves , Jennifer Stamps , Tawanda Zidenga , Stephanie Willette
Abstract: The current inventive technology includes novel systems, methods and compositions for the in vivo production, modification and isolation of terpene compounds from Cannabis or other plants. In particular, the invention provides systems and methods for high level in vivo biosynthesis of water-soluble terpene compounds. In one preferred embodiment, the present invention generally relates to the conversion of Cannabis sativa or hemp derived terpenes into water-soluble terpene compounds, such as terpene glycosides, glycosylated-xylosylated terpenes, and an acetylated glycoside terpenes. In one preferred aspect, the invention may include system for producing water-soluble terpene compounds in yeast and tobacco cell suspension cultures, as well as an in planta system using transgenic Cannabis or hemp plants.
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公开(公告)号：US20220152212A1
公开(公告)日：2022-05-19
申请号：US17428537
申请日：2020-02-04
Applicant: Trait Biosciences, Inc.
Inventor： Jennifer Stamps , Elton Carvalho Goncalves , Richard T. Sayre , Tawanda Zidenga , Erick Scott LeBrun , Timothy Travers
IPC: A61K47/64 , A61K31/05 , A61K31/352
Abstract: The inventive technology includes novel systems, methods, and compositions for the generation of water-soluble short-chain fatty acid phenolic compounds, preferably cannabinoids, terpenes, and other volatile compounds produced in Cannabis and other cannabinoid producing plants. In particular, the inventive technology includes novel systems and methods to solubilize short-chain fatty acid phenolic compounds, such as cannabinoids, via binding to a water soluble and readily digested carrier protein.
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公开(公告)号：US20220151977A1
公开(公告)日：2022-05-19
申请号：US17428581
申请日：2020-02-04
Applicant: Trait Biosciences, Inc.
Inventor： Jennifer Stamps , Elton Carvalho Goncalves , Richard T. Sayre , Tawanda Zidenga , Erick Scott LeBrun , Timothy Travers
IPC: A61K31/352 , A61K47/64 , A61K31/05
Abstract: The inventive technology includes novel systems, methods, and compositions for the generation of water-soluble short-chain fatty acid phenolic compounds, preferably cannabinoids, terpenes, and other volatile compounds produced in Cannabis. In particular, the inventive technology includes novel systems, methods, and compositions to solubilize short-chain fatty acid phenolic coin-pounds, such as cannabinoids, via binding to a water soluble and readily digested carrier protein such as: lipocalins, lipocalin-like, odorant-binding proteins, and odorant-binding-like proteins.
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