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公开(公告)号:US20210348204A1
公开(公告)日:2021-11-11
申请号:US17285800
申请日:2019-10-16
Applicant: Trait Biosciences, Inc.
Inventor: Richard T. Sayre , Elton Carvalho Goncalves , Jennifer Stamps , Tawanda Zidenga , Stephanie Willette
Abstract: The current inventive technology includes novel systems, methods and compositions for the in vivo production, modification and isolation of terpene compounds from Cannabis or other plants. In particular, the invention provides systems and methods for high level in vivo biosynthesis of water-soluble terpene compounds. In one preferred embodiment, the present invention generally relates to the conversion of Cannabis sativa or hemp derived terpenes into water-soluble terpene compounds, such as terpene glycosides, glycosylated-xylosylated terpenes, and an acetylated glycoside terpenes. In one preferred aspect, the invention may include system for producing water-soluble terpene compounds in yeast and tobacco cell suspension cultures, as well as an in planta system using transgenic Cannabis or hemp plants.
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公开(公告)号:US11352635B2
公开(公告)日:2022-06-07
申请号:US16929679
申请日:2020-07-15
Applicant: TRAIT BIOSCIENCES, INC.
Inventor: Richard Sayre , Maria Soto-Aguilar , Tawanda Zidenga , Elton Carvalho Goncalves
IPC: C12N15/82
Abstract: The present invention includes systems, methods and compositions for increasing trichome formation and/or density in cannabinoid producing plants, such as Cannabis and hemp. Additional aspects of the invention further include systems, methods and compositions for increasing cannabinoid and terpene biosynthetic and storage capacity in Cannabis.
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公开(公告)号:US11352634B2
公开(公告)日:2022-06-07
申请号:US16242951
申请日:2019-01-08
Applicant: Trait Biosciences, Inc.
Inventor: Richard T. Sayre , Elton Carvalho Gonçalves , Tawanda Zidenga
Abstract: The inventive technology relates to systems and methods for enhanced in vivo production, accumulation and modification of cannabinoids. In one embodiment, the invention may include systems and methods for enhanced in vivo biosynthesis of chemically-modified water-soluble cannabinoids in a whole plant, or a cell suspension culture system.
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公开(公告)号:US20190316144A1
公开(公告)日:2019-10-17
申请号:US16426059
申请日:2019-05-30
Applicant: Trait Biosciences Inc.
Inventor: Richard T. Sayre , Elton Carvalho Gonçalves , Tawanda Zidenga , Stephanie Willette
IPC: C12N15/82 , C12N9/10 , A61K31/352 , C12N9/02
Abstract: The present invention includes systems, methods and compositions for the in vivo bioconversion of water-soluble cannabinoids in plant cell suspension cultures.
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5.
公开(公告)号:US10378020B2
公开(公告)日:2019-08-13
申请号:US16110728
申请日:2018-08-23
Applicant: Trait Biosciences, Inc.
Inventor: Richard T. Sayre , Elton Carvalho Gonçalves , Tawanda Zidenga
Abstract: The inventive technology relates to systems and methods for enhanced in vivo production, accumulation and modification of cannabinoids. In one embodiment, the invention may include systems and methods for enhanced in vivo biosynthesis of chemically-modified water-soluble cannabinoids in a whole plant, or a cell suspension culture system.
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6.
公开(公告)号:US20190153460A1
公开(公告)日:2019-05-23
申请号:US16242897
申请日:2019-01-08
Applicant: Trait Biosciences, Inc.
Inventor: Richard T. Sayre , Elton Carvalho Gonçalves , Tawanda Zidenga
IPC: C12N15/82 , C12N9/08 , C07K14/415
Abstract: The inventive technology relates to systems and methods for enhanced in vivo production, accumulation and modification of cannabinoids. In one embodiment, the invention may include systems and methods for enhanced in vivo biosynthesis of chemically-modified water-soluble cannabinoids in a whole plant, or a cell suspension culture system.
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公开(公告)号:US20240301449A1
公开(公告)日:2024-09-12
申请号:US18430133
申请日:2024-02-01
Applicant: Trait Biosciences Inc.
Inventor: Richard T. Sayre , Elton Carvalho Gonçalves , Tawanda Zidenga , Stephanie Willette
IPC: C12P7/22 , A61K9/00 , A61K31/352 , A61K36/81 , C12P19/18
CPC classification number: C12P7/22 , A61K9/0056 , A61K31/352 , A61K36/81 , C12P19/18
Abstract: The present invention includes systems, methods and compositions for the in vivo bioconversion of water-soluble cannabinoid glycosides in cell cultures.
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公开(公告)号:US11905543B2
公开(公告)日:2024-02-20
申请号:US16425654
申请日:2019-05-29
Applicant: Trait Biosciences Inc.
Inventor: Richard T. Sayre , Elton Carvalho Gonçalves , Tawanda Zidenga , Stephanie Willette
IPC: C12P7/22 , A61K9/00 , C12P19/18 , A61K31/352 , A61K36/81
CPC classification number: C12P7/22 , A61K9/0056 , A61K31/352 , A61K36/81 , C12P19/18
Abstract: The present invention includes systems, methods and compositions for the in vivo bioconversion of water-soluble acetylated cannabinoid glycosides in plant cell suspension cultures.
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公开(公告)号:US20210032650A1
公开(公告)日:2021-02-04
申请号:US16929679
申请日:2020-07-15
Applicant: TRAIT BIOSCIENCES, INC.
Inventor: Richard Sayre , Maria Soto-Aguilar , Tawanda Zidenga , Elton Carvalho Goncalves
IPC: C12N15/82
Abstract: The present invention includes systems, methods and compositions for increasing trichome formation and/or density in cannabinoid producing plants, such as Cannabis and hemp. Additional aspects of the invention further include systems, methods and compositions for increasing cannabinoid and terpene biosynthetic and storage capacity in Cannabis.
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10.
公开(公告)号:US20200046639A1
公开(公告)日:2020-02-13
申请号:US16425744
申请日:2019-05-29
Applicant: Trait Biosciences Inc.
Inventor: Richard T. Sayre , Elton Carvalho Gonçalves , Tawanda Zidenga , Stephanie Willette
IPC: A61K9/00 , A61K31/7034 , A61K9/08 , A61K47/36 , A61K47/26 , A23L33/105 , A23L33/125 , C12G3/04
Abstract: The present invention includes systems, methods and compositions related to the production and use of chemically modified cannabinoid food and beverage additives having enhanced water solubility and stability.
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