公开(公告)号：US10436687B2

公开(公告)日：2019-10-08

申请号：US15887855

申请日：2018-02-02

Applicant: Theranos, Inc.

Inventor： Clarissa Lui ,  Priyanshu Gupta

IPC: G01N1/00 ,  G01N1/40 ,  G01N33/49 ,  B01L3/00

Abstract: Devices, systems and methods for holding and transferring small volume fluid samples are disclosed. Holding vessels, including holding vessels having two or more internal compartments for holding small volume fluid samples, are disclosed. Transfer vessels for receiving small volume fluid samples from such holding vessels are disclosed. Transfer vessels for combining small volume fluid samples from such holding vessels are disclosed. Methods for providing small volume fluid samples for analysis with small loss of sample are disclosed. Methods for providing small volume fluid samples for analysis using automated sample analysis devices and systems, with small loss of sample, are disclosed.

公开(公告)号：US10244973B2

公开(公告)日：2019-04-02

申请号：US15160196

申请日：2016-05-20

Applicant: Theranos, Inc.

Inventor： Elizabeth A. Holmes ,  Clarissa Lui ,  Michael Chen ,  Daniel Young

IPC: A61B5/00 ,  A61B5/15 ,  A61B5/154 ,  B01L9/06 ,  A61B5/151 ,  B01L3/00 ,  B65D25/10 ,  B65D43/16 ,  B65D81/18

Abstract: Bodily fluid sample transport systems, devices, and method are provided. In at least one embodiment described herein, methods are provided for the physical transport of small volumes of bodily fluid in liquid form from one location to another location. By way of nonlimiting example, the samples are collected in liquid form at a collection site, transported in liquid form, and arrive at an analysis site in liquid form. In many embodiments, the liquid form during transport is not held in a porous matrix, wicking material, webbing, or similar material that prevents sample for being extracted in liquid form at the destination site. In one embodiment, small volume of sample in each sample vessel is in the range of about 1 ml to about 1 microliter.

公开(公告)号：US20170020425A1

公开(公告)日：2017-01-26

申请号：US15160196

申请日：2016-05-20

Applicant: Theranos, Inc.

Inventor： Elizabeth A. Holmes ,  Clarissa Lui ,  Michael Chen ,  Daniel Young

IPC: A61B5/15 ,  B65D81/18 ,  B01L9/06 ,  B65D43/16 ,  B01L3/00 ,  A61B5/151 ,  B65D25/10

CPC classification number: A61B5/150022 ,  A61B5/1422 ,  A61B5/1438 ,  A61B5/15003 ,  A61B5/150099 ,  A61B5/150213 ,  A61B5/150305 ,  A61B5/150343 ,  A61B5/150389 ,  A61B5/150473 ,  A61B5/150732 ,  A61B5/15074 ,  A61B5/150755 ,  A61B5/150786 ,  A61B5/15105 ,  A61B5/1545 ,  B01L3/5082 ,  B01L9/06 ,  B01L2200/025 ,  B01L2200/185 ,  B01L2300/021 ,  B01L2300/12 ,  B01L2300/1822 ,  B01L2300/1855 ,  B01L2300/1894 ,  B65D25/108 ,  B65D43/16 ,  B65D81/18

Abstract: Bodily fluid sample transport systems, devices, and method are provided. In at least one embodiment described herein, methods are provided for the physical transport of small volumes of bodily fluid in liquid form from one location to another location. By way of nonlimiting example, the samples are collected in liquid form at a collection site, transported in liquid form, and arrive at an analysis site in liquid form. In many embodiments, the liquid form during transport is not held in a porous matrix, wicking material, webbing, or similar material that prevents sample for being extracted in liquid form at the destination site. In one embodiment, small volume of sample in each sample vessel is in the range of about 1 ml to about 1 microliter.

Abstract translation: 提供了体液样品输送系统，装置和方法。 在本文描述的至少一个实施例中，提供了用于将液体形式的小体积体液从一个位置物理运输到另一个位置的方法。 通过非限制性的实例，将样品以液体形式收集在收集部位，以液体形式运输，并以液体形式到达分析部位。 在许多实施方案中，运输期间的液体形式不保持在多孔基质，芯吸材料，织带或类似材料中，以防止样品在目的地位置以液体形式提取。 在一个实施方案中，每个样品容器中的小体积样品在约1ml至约1微升的范围内。

公开(公告)号：USD748280S1

公开(公告)日：2016-01-26

申请号：US29528999

申请日：2015-06-02

Applicant: Theranos, Inc.

Designer： Clarissa Lui

公开(公告)号：US20170122846A1

公开(公告)日：2017-05-04

申请号：US15290248

申请日：2016-10-11

Applicant: Theranos, Inc.

Inventor： Elizabeth A. Holmes ,  Clarissa Lui ,  Michael Chen ,  Daniel Young

IPC: G01N1/20 ,  B01L3/00 ,  G01N1/38

CPC classification number: G01N1/20 ,  A61B5/150022 ,  A61B5/15003 ,  A61B5/150099 ,  A61B5/150251 ,  A61B5/150305 ,  A61B5/150343 ,  A61B5/150351 ,  A61B5/150389 ,  A61B5/150503 ,  A61B5/150572 ,  A61B5/150732 ,  A61B5/150755 ,  A61B5/150793 ,  A61B5/150824 ,  A61B5/150954 ,  A61B5/150984 ,  A61B5/150992 ,  A61B5/15109 ,  A61B5/15111 ,  A61B5/15113 ,  A61B5/15117 ,  A61B5/15186 ,  A61B5/154 ,  B01L3/502 ,  B01L3/52 ,  B01L3/527 ,  B01L3/545 ,  B01L2200/185 ,  B01L2300/022 ,  B01L2300/044 ,  B01L2300/0672 ,  B01L2300/0832 ,  B01L2300/0864 ,  B01L2300/0877 ,  B01L2300/18 ,  B01L2300/1822 ,  B01L2400/0409 ,  G01N1/38 ,  G01N1/4077 ,  G01N2001/005 ,  G01N2001/4083 ,  G01N2035/00326

Abstract: Bodily fluid sample collection systems, devices, and method are provided. The sample is collected at a first location and subjected to a first sample processing step. The sample may be shipped to a second location and subjected to a second sample processing step that does not introduce contaminants into a plasma portion of the sample formed from the first processing step. The sample may also be mixed with other material(s) in the collection device.

公开(公告)号：US20160245810A1

公开(公告)日：2016-08-25

申请号：US15041421

申请日：2016-02-11

Applicant: Theranos, Inc.

Inventor： Pranav Patel ,  Scott Tabakman ,  Kamila Belhocine ,  Aaron Richardson ,  Josephine Lee ,  Clarissa Lui ,  Sharada Sivaraman ,  Sheena Menzes ,  Surekha Gangakhedkar ,  Elizabeth A. Holmes

IPC: G01N33/569

CPC classification number: G16H10/40 ,  C12Q1/68 ,  C12Q1/6806 ,  C12Q1/6844 ,  C12Q1/689 ,  C12Q1/6893 ,  C12Q1/6895 ,  C12Q1/70 ,  C12Q1/701 ,  C12Q1/703 ,  C12Q1/705 ,  C12Q1/706 ,  C12Q1/707 ,  C12Q2521/501 ,  C12Q2600/158 ,  C12Q2600/16 ,  G01N33/56911 ,  G01N33/56916 ,  G01N33/56938 ,  G01N33/56944 ,  G01N33/56983 ,  G01N33/56988 ,  G01N33/56994 ,  G01N35/10 ,  G01N2035/00237 ,  G01N2333/11 ,  G01N2469/10 ,  G01N2469/20 ,  G06F19/3456 ,  G16H20/10 ,  G16H50/20 ,  Y02A50/58 ,  Y02A90/24 ,  Y02A90/26 ,  Y10T436/11

Abstract: Systems, methods, and devices for detecting infections in a clinical sample are provided. Small-volume clinical samples obtained at a point-of-service (POS) location and may be tested at the POS location for multiple markers for multiple diseases, including upper and lower respiratory diseases. Samples may be tested for cytokines, or for inflammation indicators. Dilution of samples, or levels of detection, may be determined by the condition or past history of a subject. Test results may be obtained within a short amount of time after sample placement in a testing device, or within a short amount of time after being obtained from the subject. A prescription for treatment of a detected disorder may be provided, and may be filled, at the POS location. A bill may be automatically generated for the testing, or for the prescription, may be automatically sent to an insurance provider, and payment may be automatically obtained.

Abstract translation: 提供了用于检测临床样品中的感染的系统，方法和装置。 在POS服务点（POS）位置获得的小批量临床样品，可在POS位置进行多种疾病包括上呼吸道疾病和下呼吸道疾病的多种标志物的检测。 可以测试样品的细胞因子或炎症指标。 样本的稀释或检测水平可以由受试者的状况或过去的历史来确定。 试样结果可以在试样放置在试验装置中之后的短时间内或在从受试者获得后的短时间内获得。 可以在POS位置提供用于治疗检测到的病症的处方，并且可以填充处方。 可以自动生成帐单用于测试，或者可以将处方自动发送给保险提供商，并且可以自动获得支付。

公开(公告)号：USD733317S1

公开(公告)日：2015-06-30

申请号：US29466710

申请日：2013-09-10

Applicant: Theranos, Inc.

Designer： Clarissa Lui

公开(公告)号：USD733316S1

公开(公告)日：2015-06-30

申请号：US29466443

申请日：2013-09-08

Applicant: Theranos, Inc.

Designer： Clarissa Lui

公开(公告)号：USD791964S1

公开(公告)日：2017-07-11

申请号：US29568769

申请日：2016-06-21

Applicant: Theranos, Inc.

Designer： Clarissa Lui

公开(公告)号：US20170168051A1

公开(公告)日：2017-06-15

申请号：US15356972

申请日：2016-11-21

Applicant: Theranos, Inc.

Inventor： Clarissa Lui ,  Elizabeth A. Holmes

IPC: G01N33/569 ,  C12Q1/68 ,  G01N35/10 ,  C12Q1/70

Abstract: Systems, methods, and devices for detecting infections in a clinical sample are provided. Small-volume clinical samples obtained at a point-of-service (POS) location and may be tested at the POS location for multiple markers for multiple diseases, including upper and lower respiratory diseases. Samples may be tested for cytokines, or for inflammation indicators. Dilution of samples, or levels of detection, may be determined by the condition or past history of a subject. Test results may be obtained within a short amount of time after sample placement in a testing device, or within a short amount of time after being obtained from the subject. A prescription for treatment of a detected disorder may be provided, and may be filled, at the POS location. A bill may be automatically generated for the testing, or for the prescription, may be automatically sent to an insurance provider, and payment may be automatically obtained.