摘要:
A 2-iminopyrrolidine derivative represented by the formula: {wherein ring B represents a benzene ring, pyridine ring, etc.; R101–R103 represent hydrogen, halogen, C1-6 alkyl, etc.; R5 represents hydrogen, C1-6 alkyl, C1-6 alkoxy-C1-6 alkyl, etc.; R6 represents hydrogen, C1-6 alkyl, C1-6 alkyloxycarbonyl, etc.; Y1 represents a single bond, —CH2—, etc.; Y2 represents a single bond, —CO—, etc.; and Ar represents hydrogen, a group represented by the formula: [wherein R10—R14 represent hydrogen, C1-6 alkyl, hydroxyl, C1-6 alkoxy, etc.; and R11 and R12 or R12 and R13 may bond together to form a 5- to 8-membered heterocyclic ring], etc.}, or a salt thereof.
摘要翻译:由下式表示的2-亚氨基吡咯烷衍生物:其中环B表示苯环,吡啶环等; R 101为-O-,卤素,C 1-6烷基等; R 5表示氢,C 1-6烷基,C 1-6烷氧基-C 1-6烷基 等等 R 6表示氢,C 1-6烷基,C 1-6烷氧基羰基等; Y 1表示单键,-CH 2 - 等; Y 2表示单键,-CO-等; 和Ar表示氢,由下式表示的基团:其中R 10 -R 14表示氢,C 1-6烷基,羟基 C 1-6烷氧基等; 并且R 11和R 12或R 12和R 13可以键合在一起形成5-8个 - 杂环]等,或其盐。
摘要:
A cyclic amidine derivative represented by the formula: [wherein R1, R2 and R3 represent hydrogen, C1-6 alkyl, aryl-C1-6 alkyl, etc.; R4, R5 and R7 represent hydrogen, C1-6 alkyl, etc.; Z represents 0 or 1; R6 represents hydrogen, C1-6 alkyl, C1-6 alkyloxycarbonyl, etc.; n represents 1 or 2; Y1 represents a single bond, —CH2—, etc.; Y2 represents a single bond, —CO—, etc.; Ar represents hydrogen, a group represented by the formula: [wherein R10-R14 represent hydrogen, C1-6 alkyl, hydroxyl, C1-6 alkoxy, etc., and R11 and R12 or R12 and R13 may bond together to form a 5- to 8-membered heterocycle], etc.] or a salt thereof.
摘要:
A 2-iminopyrrolidine derivative represented by the formula: {wherein ring B represents a benzene ring, pyridine ring, etc.; R101-R103 represent hydrogen, halogen, C1-6 alkyl, etc.; R5 represents hydrogen, C1-6 alkyl, C1-6 alkoxy-C1-6 alkyl, etc.; R6 represents hydrogen, C1-6 alkyl, C1-6 alkyloxycarbonyl, etc.; Y1 represents a single bond, —CH2—, etc.; Y2 represents a single bond, —CO—, etc.; and Ar represents hydrogen, a group represented by the formula: [wherein R10-R14 represent hydrogen, C1-6 alkyl, hydroxyl, C1-6 alkoxy, etc.; and R11 and R12 or R12 and R13 may bond together to form a 5- to 8-membered heterocyclic ring], etc.}, or a salt thereof.
摘要翻译:由下式表示的2-亚氨基吡咯烷衍生物:其中环B表示苯环,吡啶环等; R 101为-O-,卤素,C 1-6烷基等; R 5表示氢,C 1-6烷基,C 1-6烷氧基-C 1-6烷基 等等 R 6表示氢,C 1-6烷基,C 1-6烷氧基羰基等; Y 1表示单键,-CH 2 - 等; Y 2表示单键,-CO-等; 和Ar表示氢,由下式表示的基团:其中R 10 -R 14表示氢,C 1-6烷基,羟基 C 1-6烷氧基等; 并且R 11和R 12或R 12和R 13可以键合在一起形成5-8个 - 杂环]等,或其盐。
摘要:
A 2-iminoimidazole derivative represented by the formula: {wherein R1, R2 and R3 represent hydrogen, optionally substituted C1-6 alkyl, etc.; R6 represents hydrogen, C1-6 alkyl, C1-6 alkyloxycarbonyl, etc.; Y1 represents a single bond, —CH2—, etc.; Y2 represents a single bond, —CO—, etc.; and Ar represents hydrogen, a group represented by the formula: [wherein R10–R14 represent hydrogen, C1-6 alkyl, hydroxyl, C1-6 alkoxy, etc., and R11 and R12 or R12 and R13 may bond together to form a 5- to 8-membered heterocycle], etc.}or salt thereof.
摘要:
A 2-iminopyrrolidine derivative represented by the formula: {wherein ring B represents a benzene ring, pyridine ring, etc.; R101-R103 represent hydrogen, halogen, C1-6 alkyl, etc.; R5 represents hydrogen, C1-6 alkyl, C1-6 alkoxy-C1-6 alkyl, etc.; R6 represents hydrogen, C1-6 alkyl, C1-6 alkyloxycarbonyl, etc.; Y1 represents a single bond, —CH2—, etc.; Y2 represents a single bond, —CO—, etc.; and Ar represents hydrogen, a group represented by the formula: [wherein R10—R14 represent hydrogen, C1-6 alkyl, hydroxyl, C1-6 alkoxy, etc.; and R11 and R12 or R12 and R13 may bond together to form a 5- to 8-membered heterocyclic ring], etc.}, or a salt thereof.
摘要翻译:由下式表示的2-亚氨基吡咯烷衍生物:其中环B表示苯环,吡啶环等; R 101 -R 103代表氢,卤素,C 1-6烷基等; R 5表示氢,C 1-6烷基,C 1-6烷氧基-C 1-6烷基等; R 6表示氢,C 1-6烷基,C 1-6烷氧羰基等; Y 1表示单键,-CH 2 - 等; Y 2表示单键,-CO-等; 并且Ar表示氢,由下式表示的基团:其中R 10 -R 14表示氢,C 1-6烷基,羟基,C 1-6烷氧基等; 和R 11和R 12或R 12和R 13可以键合在一起形成5-至8-元杂环]等,或其盐。
摘要:
A cyclic amidine derivative represented by the formula: [wherein R1, R2 and R3 represent hydrogen, C1-6 alkyl, aryl-C1-6 alkyl, etc.; R4, R5 and R7 represent hydrogen, C1-6 alkyl, etc.; Z represents 0 or 1; R6 represents hydrogen, C1-6 alkyl, C1-6 alkyloxycarbonyl, etc.; n represents 1 or 2; Y1 represents a single bond, —CH2—, etc.; Y2 represents a single bond, —CO—, etc.; Ar represents hydrogen, a group represented by the formula: [wherein R10-R14 represent hydrogen, C1-6 alkyl, hydroxyl, C1-6 alkoxy, etc., and R11 and R12 or R12 and R13 may bond together to form a 5- to 8-membered heterocycle], etc.] or a salt thereof.
摘要:
The present invention discloses compounds and compositions of formula (I): having inhibitory activity on activation of STAT6, wherein X represents quinoline, isoquinoline, quinazoline or imidazopyridine; Y represents phenyl, piperazine, pyridine, thiophene, thiazole, oxathiazole or oxathiadiazole; and variables Z, n, R1, R2, R3 and R4 are as defined in the claims.
摘要:
An information processing apparatus includes a correlation unit that correlates distance information indicating a distance to an emission position of electromagnetic waves emitted in a shooting direction of a plurality of image pickup units with a first pixel in a first image that constitutes images taken by the image pickup units, the distance information being obtained based on reflected waves of the electromagnetic waves and the first pixel corresponding to the emission position of the electromagnetic waves, and a generation unit that generates a parallax image by using the distance information correlated with the first pixel for parallax computation of pixels in a second image that constitutes the images.
摘要:
An object detection apparatus includes an incident optical system, which includes light source units and a combining unit combining light beams emitted from the light source units; a deflection unit including rotating reflection parts that deflect the light beams to scan and be irradiated on a predetermined range of an object; an imaging unit forming an image based on the light from the predetermined range of the object; and an optical detection unit detecting the object based on the light received via the imaging unit. Further the combining unit combines the light beams such that each of the combined light beams passes a single light path when projected onto a predetermined plane, and each of the light paths exists outside a region of the deflection unit when projected onto the first plane.
摘要:
A fixing device includes a fixing unit, a power supply unit, a pressure applying unit, and a controller. The fixing unit fixes toner onto a recording medium, using heat generated by a heat generator. The power supply unit supplies power to drive the fixing unit. The pressure applying unit applies pressure to the recording medium in a nip part between the pressure applying unit and the fixing unit. When plural recording media are sequentially transported, the controller controls the power supply unit to supply power during a first time period from when a trailing edge of one of the recording media passes the nip part to when a leading edge of the subsequent recording medium arrives at the nip part, in accordance with a relationship between the first time period and a second time period required to start the supply of power after the supply of power is stopped.