公开(公告)号：US20190210940A1

公开(公告)日：2019-07-11

申请号：US16325676

申请日：2017-08-16

申请人： Organofuel Sweden AB

发明人： Armando Córdova ,  Samson Afewerki

IPC分类号： C07B35/02 ,  C07C45/29 ,  C07C45/30 ,  C07C45/62 ,  C07C45/72

CPC分类号： C07B35/02 ,  C07B31/00 ,  C07B33/00 ,  C07B35/04 ,  C07C45/29 ,  C07C45/294 ,  C07C45/30 ,  C07C45/62 ,  C07C45/72 ,  C07D319/06 ,  Y02P20/584 ,  C07C47/02 ,  C07C47/21 ,  C07C47/11

摘要： Embodiments herein concerns the eco-friendly conversion of simple alcohols to linear or branched functionalized alkanes, by integrated catalysis. The alcohols are firstlyoxidized either chemically or enzymatically to the corresponding aldehydes or ketones, followed by aldol condensations using a catalyst to give the corresponding enals or enones. The enals or enones are subsequently and selectively hydrogenated using a recyclable heterogeneous metal catalyst, organocatalyst or an enzyme to provide linear or branched functionalized alkanes with an aldehyde, keto- or alcohol functionality. The process is also iterative and can be further extended by repeating the above integrated catalysis for producing long-chain functionalized alkanes from simple alcohols.

公开(公告)号：US10995154B2

公开(公告)日：2021-05-04

申请号：US15778945

申请日：2016-11-23

申请人： Organofuel Sweden AB

发明人： Armando Córdova ,  Samson Afewerki

IPC分类号： C08B1/06 ,  C08B11/00 ,  C08B15/05 ,  C08L1/26 ,  C08L1/08 ,  C08L97/02 ,  B82Y30/00

摘要： The present disclosure relates to the environmentally preparation of nanocellulose and derivatives thereof. The invention further relates to the preparation of cellulose derivatives.

公开(公告)号：US10308588B2

公开(公告)日：2019-06-04

申请号：US15536295

申请日：2015-12-15

申请人： ORGANOFUEL SWEDEN AB

发明人： Armando Córdova ,  Carlos Palo-Nieto ,  Samson Afewerki

IPC分类号： C07D307/34 ,  C07C209/28 ,  C07D317/58 ,  C07C41/18 ,  C07C41/26 ,  C07C45/38 ,  C07C213/02 ,  C07C227/08 ,  C07C231/02 ,  C07D307/52 ,  B01J23/44 ,  B01J31/02 ,  B01J35/00 ,  B01J35/04

摘要： A mild and efficient synthesis of primary amines and amides from aldehydes or ketones using a heterogeneous metal catalyst and amine donor is disclosed. The initial heterogeneous metal-catalyzed reaction between the carbonyl and the amine donor components is followed by the addition of a suitable acylating agent component in one-pot, thus providing a catalytic one-pot three-component synthesis of amides. Integration of enzyme catalysis allows for eco-friendly one-pot co-catalytic synthesis of amides from aldehyde and ketone substrates, respectively. The process can be applied to asymmetric synthesis or to the co-catalytic one-pot three-component synthesis of capsaicin and its analogues from vanillin or vanillyl alcohol. A co-catalytic reductive amination/dynamic kinetic resolution (dkr) relay sequence for the asymmetric synthesis of optically active amides from ketones is disclosed. Implementation of a catalytic reductive amination/kinetic resolution (kr) relay sequence produces the corresponding optically active amide product and optical active primary amine product with the opposite stereochemistry from the starting ketones.

公开(公告)号：US10287226B2

公开(公告)日：2019-05-14

申请号：US15522838

申请日：2015-10-30

申请人： ORGANOFUEL SWEDEN AB

发明人： Armando Córdova ,  Samson Afewerki ,  Carlos Palo-Nieto

IPC分类号： C07C41/18 ,  C07C29/145 ,  C07C41/26 ,  C07C209/32 ,  C07C209/68 ,  C07C45/30 ,  C07C45/51 ,  C10G3/00 ,  C07C1/22 ,  C07C43/205 ,  C07C43/23 ,  C07C47/575 ,  C07C209/36 ,  C07C211/45 ,  C10L1/02 ,  C10L1/04

摘要： A method of reducing a C—O bond to the corresponding C—H bond in a substrate, which could be a benzylic alcohol, allylic alcohol, ester or an ether bond beta to a hydroxyl group or alpha to a carbonyl group using a recyclable metal catalyst system. The recyclable catalyst system is also applicable to reducing a C═O bond to the corresponding C—OH bond and then C—H bond. These methodologies can be linked in one-pot to selective oxidation and depolymerizations of aromatic polyols such as lignin.