公开(公告)号：US20180164569A1

公开(公告)日：2018-06-14

申请号：US15828980

申请日：2017-12-01

Applicant: OLYMPUS CORPORATION

Inventor： Brendan BRINKMAN ,  Yoshihiro SHIMADA

IPC: G02B21/34 ,  G02B21/26 ,  G02B21/06 ,  G02B21/36 ,  G02B27/30 ,  G02B21/16 ,  G01N21/64

CPC classification number: G02B21/34 ,  G01N21/6452 ,  G01N21/6458 ,  G01N2021/6478 ,  G02B21/06 ,  G02B21/10 ,  G02B21/16 ,  G02B21/26 ,  G02B21/361 ,  G02B27/30

Abstract: This microplate includes: container sections having wells that open at a first plane and that accommodate samples; and a connection section connecting a plurality of rows of the container sections to be arrayed in a manner where the rows are spaced from each other in a direction along the first plane, wherein each of the container sections includes: at least one side wall section that is optically transparent at at least a portion thereof; and a bottom surface section that is disposed on a second plane on a side opposite from the first plane and that is optically transparent at at least a portion thereof, a recessed section is provided between neighboring rows of the container sections, and the recessed section allows an optical member to be inserted thereinto via the second plane, wherein the optical member introduces sheet-shaped illumination light to the well via the side wall section.

公开(公告)号：US20180259761A1

公开(公告)日：2018-09-13

申请号：US15872149

申请日：2018-01-16

Applicant: OLYMPUS CORPORATION

Inventor： Brendan BRINKMAN ,  Yoshihiro SHIMADA ,  Daisuke NISHIWAKI

IPC: G02B21/33 ,  G01N21/64 ,  G02B21/24

CPC classification number: G02B21/33 ,  G01N21/6458 ,  G01N2021/6463 ,  G02B21/241

Abstract: An immersion liquid holder 2 is an immersion liquid holder that is used for an observation device 10 for observing sample S by using an immersion method, and includes a supporting member 2b configured to support an absorption member 3 that has absorbed an immersion liquid and a connection unit 2c configured to relatively fix the absorption member 3 that has absorbed the immersion liquid with respect to an optical system, which is an optical system included in the observation device 10, and to fix the absorption member 3 on an optical path of the optical system 1, by fixing the supporting member 2b to the observation device 10.

公开(公告)号：US20170031150A1

公开(公告)日：2017-02-02

申请号：US15217267

申请日：2016-07-22

Applicant: OLYMPUS CORPORATION

Inventor： Brendan BRINKMAN

IPC: G02B21/33 ,  G02B21/26 ,  G02B21/00

CPC classification number: G02B21/33 ,  G01N21/253 ,  G01N2021/0357 ,  G02B21/0088 ,  G02B21/24 ,  G02B21/26

Abstract: This inverted microscope comprises the following elements: an immersion objective lens, a medium container which is disposed above the immersion objective lens with a gap, and which has a bottom surface having a transparent portion and being capable of retaining a first immersion medium between the transparent portion and the immersion objective lens, and also which is capable of storing inside thereof a second immersion medium having a refractive index which is the same as or similar to that of the first immersion medium; and a movable stage to support a sample container, which accommodates a specimen, in a horizontally movable manner inside the medium container and which has a transparent portion in at least a part of a bottom surface thereof.

Abstract translation: 这种倒置显微镜包括以下元件：浸没物镜，设置在具有间隙的浸没物镜上方的介质容器，并且具有底表面具有透明部分并且能够将第一浸没介质保持在透明 并且还能够在其内部存储具有与第一浸渍介质的折射率相同或类似的折射率的第二浸渍介质; 以及可移动台，用于将容纳样本的样本容器以可水平移动的方式支撑在所述介质容器内，并且在其底表面的至少一部分中具有透明部分。

公开(公告)号：US20180361377A1

公开(公告)日：2018-12-20

申请号：US15985022

申请日：2018-05-21

Applicant: OLYMPUS CORPORATION

Inventor： Brendan BRINKMAN ,  Yoshihiro SHIMADA

IPC: B01L3/00 ,  C12M1/12 ,  G01N35/10 ,  G01N21/01 ,  G01N21/88

Abstract: Provided is a sample manufacturing method that includes: a step of forming a hanging drop consisting of a liquid drop of a medium solution in a hanging state while causing at least one cell aggregate to be encapsulated in the liquid drop of the medium solution, the medium solution becoming substantially transparent upon gelling or solidifying; and a step of causing the hanging drop to gel or solidify by causing a promoting factor that promotes gelling or solidification of the medium solution to act on the hanging drop.

公开(公告)号：US20180052314A1

公开(公告)日：2018-02-22

申请号：US15678854

申请日：2017-08-16

Applicant: OLYMPUS CORPORATION

Inventor： Brendan BRINKMAN ,  Yoshihiro SHIMADA

IPC: G02B21/33 ,  G02B21/26 ,  G02B21/34 ,  G02B21/36 ,  G01N21/03 ,  G02B21/16 ,  G01N21/64 ,  G02B21/08 ,  G02B21/22

CPC classification number: G02B21/33 ,  G01N21/0303 ,  G01N21/6458 ,  G01N2021/0342 ,  G01N2021/0367 ,  G02B21/006 ,  G02B21/0088 ,  G02B21/086 ,  G02B21/16 ,  G02B21/22 ,  G02B21/26 ,  G02B21/34 ,  G02B21/361

Abstract: Provided is a microscope including: a chamber storing a solution in which a cuvette accommodating a solution together with a sample is immersed and that has an index of refraction identical to that of the solution; an immersion objective lens being placed outside the chamber and collecting light from the sample; a camera acquiring an image of the light collected by the lens; a targeting section moving the lens in a direction along a detection light axis thereof; and a movable stage supporting the cuvette in the chamber so as to be movable in at least a direction along the detection light axis. Each of the cuvette and the chamber has a transparent section that can transmit light coming from the sample. The lens is placed so as to face the transparent section of the cuvette with the transparent section of the chamber interposed therebetween.