公开(公告)号：US09768162B2

公开(公告)日：2017-09-19

申请号：US13788464

申请日：2013-03-07

Applicant: Nanohmics, Inc.

Inventor： Steve M. Savoy ,  Jeremy J. John ,  Daniel R. Mitchell ,  Michael K. McAleer

IPC: H01L29/06 ,  H01L47/02 ,  H01L27/088 ,  G01N27/414 ,  H01L27/146 ,  B82Y99/00

CPC classification number: H01L27/088 ,  B82Y99/00 ,  G01N27/4148 ,  H01L27/1462 ,  H01L29/0673 ,  Y10S977/762

Abstract: An array of sensor devices, each sensor including a set of semiconducting nanotraces having a width less than about 100 nm is provided. Method for fabricating the arrays is disclosed, providing a top-down approach for large arrays with multiple copies of the detection device in a single processing step. Nanodimensional sensing elements with precise dimensions and spacing to avoid the influence of electrodes are provided. The arrays may be used for multiplex detection of chemical and biomolecular species. The regular arrays may be combined with parallel synthesis of anchor probe libraries to provide a multiplex diagnostic device. Applications for gas phase sensing, chemical sensing and solution phase biomolecular sensing are disclosed.

公开(公告)号：US20150331082A1

公开(公告)日：2015-11-19

申请号：US14531247

申请日：2014-11-03

Applicant: Nanohmics, Inc.

Inventor： Byron G. Zollars ,  Steve M. Savoy ,  Michael W. Mayo ,  Daniel R. Mitchell

IPC: G01S3/782 ,  G01J1/04 ,  G01S3/781

CPC classification number: G01S3/782 ,  G01J1/0411 ,  G01J1/0422 ,  G01J1/0492 ,  G01J1/4257 ,  G01J2001/4266 ,  G01J2003/2813 ,  G01S3/781 ,  G01S3/784 ,  H01L27/14621 ,  H01L27/14625 ,  H01L31/02327

Abstract: Method and apparatus for determining direction from which electromagnetic radiation originates and spectral characteristics of the radiation are provided. Lenses, diffraction gratings, which may be present on the surface of the lenses, and mirrors direct radiation to a photodetector. Lens and grating parameters, along with the location, size, relative spacing and orientation of diffracted orders of radiation detected by the photodetector are used for determining direction from which the radiation originates.

Abstract translation: 确定电磁辐射起源的方向和辐射的光谱特性的方法和装置。 透镜，可能存在于透镜表面上的衍射光栅，并且将直接辐射镜反射到光电检测器。 透镜和光栅参数以及由光电检测器检测的辐射衍射级数的位置，大小，相对间距和取向用于确定辐射源自的方向。

公开(公告)号：US20130193405A1

公开(公告)日：2013-08-01

申请号：US13788464

申请日：2013-03-07

Applicant: NANOHMICS, INC.

Inventor： Steve M. Savoy ,  Jeremy J. John ,  Daniel R. Mitchell ,  Michael K. McAleer

IPC: H01L27/088

CPC classification number: H01L27/088 ,  B82Y99/00 ,  G01N27/4148 ,  H01L27/1462 ,  H01L29/0673 ,  Y10S977/762

Abstract: An array of sensor devices, each sensor including a set of semiconducting nanotraces having a width less than about 100 nm is provided. Method for fabricating the arrays is disclosed, providing a top-down approach for large arrays with multiple copies of the detection device in a single processing step. Nanodimensional sensing elements with precise dimensions and spacing to avoid the influence of electrodes are provided. The arrays may be used for multiplex detection of chemical and biomolecular species. The regular arrays may be combined with parallel synthesis of anchor probe libraries to provide a multiplex diagnostic device. Applications for gas phase sensing, chemical sensing and solution phase biomolecular sensing are disclosed.

Abstract translation: 提供一组传感器装置，每个传感器包括一组宽度小于约100nm的半导体纳米管。 公开了用于制造阵列的方法，在单个处理步骤中为检测装置的多个拷贝的大阵列提供自上而下的方法。 提供具有精确尺寸和间隔的避免电极影响的纳米感测元件。 阵列可用于化学和生物分子物种的多重检测。 常规阵列可以与锚探针库的并行合成组合以提供多路诊断装置。 公开了用于气相感测，化学感测和溶液相生物分子感测的应用。

公开(公告)号：US20210389222A1

公开(公告)日：2021-12-16

申请号：US17412679

申请日：2021-08-26

Applicant: Nanohmics, Inc.

Inventor： Steve M. Savoy ,  Elzbieta A. Ledwosinska ,  Jeremy J. John ,  Kyle W. Hoover ,  Daniel R. Mitchell ,  Chris W. Mann ,  Alexander P. Greis

IPC: G01N15/06

Abstract: An apparatus comprises a housing defining a chamber that has a liquid disposed therein, and a sensor submerged in the liquid. The sensor comprises a porous conductive film on a substrate, and the film comprises chemiresistive semiconducting metal oxide structures. The sensor also comprises an electrode pair operably connected to the porous conductive film for generating electric current in the film and for detecting a change in an electrical property of the film. The apparatus can be used to detect, identify, and quantify ions and molecules in a liquid sample. Molecules and ions, in a liquid sample, that interact with the porous conductive film can cause a change in an electrical property of the film. The change in electrical property of the film can be correlated with the presence and amount of the molecules or ions.

公开(公告)号：US20190383720A1

公开(公告)日：2019-12-19

申请号：US16434172

申请日：2019-06-06

Applicant: Nanohmics, Inc.

Inventor： Steve M. Savoy ,  Elzbieta A. Ledwosinska ,  Jeremy J. John ,  Kyle W. Hoover ,  Daniel R. Mitchell ,  Chris W. Mann ,  Alexander P. Greis

IPC: G01N15/06

Abstract: An apparatus comprises a housing defining a chamber that has a liquid disposed therein, and a sensor submerged in the liquid. The sensor comprises a porous conductive film on a substrate, and the film comprises chemiresistive semiconducting metal oxide structures. The sensor also comprises an electrode pair operably connected to the porous conductive film for generating electric current in the film and for detecting a change in an electrical property of the film. The apparatus can be used to detect, identify, and quantify ions and molecules in a liquid sample. Molecules and ions, in a liquid sample, that interact with the porous conductive film can cause a change in an electrical property of the film. The change in electrical property of the film can be correlated with the presence and amount of the molecules or ions.

公开(公告)号：US10386365B2

公开(公告)日：2019-08-20

申请号：US15372343

申请日：2016-12-07

Applicant: Nanohmics, Inc

Inventor： Steve M. Savoy ,  Kyle W. Hoover ,  Chris W. Mann ,  Daniel R. Mitchell ,  Jeremy J. John ,  Alexander P. Greis

IPC: G01N33/543

Abstract: Methods and sensors for detection and quantification of one or more analyte in a test sample are described. A response profile of an ion sensor to a control sample of a known interrogator ion is determined. The ion sensor is exposed to a test sample then to a second sample comprising the known interrogator ion, and a test sample response profile of the ion sensor is determined. One or more test sample sensor response profiles are compared with one or more control sensor response profiles for detecting, identifying, and quantifying one or more analytes in the test sample.

公开(公告)号：US11988662B2

公开(公告)日：2024-05-21

申请号：US15372075

申请日：2016-12-07

Applicant: Nanohmics, Inc.

Inventor： Steve M. Savoy ,  Kyle W. Hoover ,  Daniel R. Mitchell ,  Jeremy J. John ,  Chris W. Mann ,  Alexander P. Greis

IPC: G01N33/53 ,  G01N33/00 ,  G01N33/497

CPC classification number: G01N33/5308 ,  G01N33/0008 ,  G01N33/0031 ,  G01N33/0047 ,  G01N33/497 ,  G01N2033/4975

Abstract: Methods and sensors for the detection, identification, and quantification of one or more gas species, including volatile organic compounds, in a test sample are described. Methods employ gas sensors comprising a diffusion matrix present on the sensor surface. A gas analyte in a test sample diffuses through the matrix and is detected upon interaction of the analyte with the sensor. A response profile of a gas sensor to a gas analyte in the test sample is compared to a control gas sensor response profile determined in a similar manner for a known gas species. Comparisons of test sample and control sample sensor response profiles enable detection, identification, and quantification of a gas species analyte in a test sample.

公开(公告)号：US10386351B2

公开(公告)日：2019-08-20

申请号：US15372248

申请日：2016-12-07

Applicant: Nanohmics, Inc.

Inventor： Steve M. Savoy ,  Kyle W. Hoover ,  Daniel R. Mitchell ,  Jeremy J. John ,  Chris W. Mann ,  Alexander P. Greis

IPC: G01N33/00 ,  G01N27/12

Abstract: Methods and sensors for detection and quantification of one or more analyte in a test sample are described. A response profile of a gas sensor to a control sample of a known interrogator gas is determined. The gas sensor is exposed to a test sample then to a second sample comprising the known interrogator gas, and a test sample response profile of the gas sensor is determined. One or more test sample sensor response profiles are compared with one or more control sensor response profiles for detecting, identifying, and quantifying one or more analytes in the test sample.

公开(公告)号：US09335398B2

公开(公告)日：2016-05-10

申请号：US14531247

申请日：2014-11-03

Applicant: Nanohmics, Inc.

Inventor： Byron G. Zollars ,  Steve M. Savoy ,  Michael W. Mayo ,  Daniel R. Mitchell

IPC: H01L27/14 ,  G01S3/782 ,  G01S3/781 ,  G01J1/42 ,  G01J1/04 ,  G01S3/784 ,  H01L31/0232 ,  H01L27/146 ,  G01J3/28

CPC classification number: G01S3/782 ,  G01J1/0411 ,  G01J1/0422 ,  G01J1/0492 ,  G01J1/4257 ,  G01J2001/4266 ,  G01J2003/2813 ,  G01S3/781 ,  G01S3/784 ,  H01L27/14621 ,  H01L27/14625 ,  H01L31/02327

Abstract: Method and apparatus for determining direction from which electromagnetic radiation originates and spectral characteristics of the radiation are provided. Lenses, diffraction gratings, which may be present on the surface of the lenses, and mirrors direct radiation to a photodetector. Lens and grating parameters, along with the location, size, relative spacing and orientation of diffracted orders of radiation detected by the photodetector are used for determining direction from which the radiation originates.

Abstract translation: 确定电磁辐射起源的方向和辐射的光谱特性的方法和装置。 透镜，可能存在于透镜表面上的衍射光栅，并且将直接辐射镜反射到光电检测器。 透镜和光栅参数以及由光电检测器检测的辐射衍射级数的位置，大小，相对间距和取向用于确定辐射源自的方向。