-
公开(公告)号：US20190248864A1
公开(公告)日：2019-08-15
申请号：US16398498
申请日：2019-04-30
Applicant: ModernaTX, Inc.
Inventor： Jeff Lynn ELLSWORTH , Joseph Beene BOLEN , Francine Marie GREGOIRE , Justin GUILD
IPC: C07K14/705
CPC classification number: C07K14/705 , A61K38/00
Abstract: The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotide molecules encoding low density lipoprotein receptor comprising at least one mutation (e.g., an LDLR signally enhancing mutation).
-
2.发明申请公开(公告)号：US20210299278A1
公开(公告)日：2021-09-30
申请号：US17020522
申请日：2020-09-14
Applicant: ModernaTX, Inc.
Inventor： Stephane BANCEL , Tirtha CHAKRABORTY , Antonin DE FOUGEROLLES , Sayda M. ELBASHIR , Matthias JOHN , Atanu ROY , Susan WHORISKEY , Kristy M. WOOD , Paul HATALA , Jason P. SCHRUM , Kenechi EJEBE , Jeff Lynn ELLSWORTH , Justin GUILD
IPC: A61K48/00 , C12N15/85 , C07K14/47 , C07K14/62 , A61K31/7115 , C12N9/88 , A61K9/127 , C12N15/11 , C07K14/705 , C07K14/505 , C07K14/535 , C12N9/64 , C12N9/10 , C12N9/00 , C12N9/42 , C12N15/87 , C12P13/04 , A61K38/45 , C07K14/005 , C12N9/16 , C12N9/24 , C12N15/52 , A61K38/17 , C07K14/435 , C12P21/00 , C07K14/485 , C07H21/02 , C07K14/475 , C07K14/495 , C07K14/525 , C07K14/54 , C07K14/56 , C07K14/61 , C07K14/745 , C07K16/28 , C07K16/40 , C12N9/02 , C12N9/12 , C12N9/68 , A61K47/54 , A61K9/14 , A61K9/51 , A61K38/18 , A61K38/19 , A61K38/21 , A61K38/48 , C07K14/515 , C07K16/00
Abstract: The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides, primary transcripts and mmRNA molecules.
-
公开(公告)号：US20170368200A1
公开(公告)日：2017-12-28
申请号：US15425645
申请日：2017-02-06
Applicant: ModernaTX, Inc.
Inventor： Stephane BANCEL , Tirtha CHAKRABORTY , Antonin DE FOUGEROLLES , Sayda M. ELBASHIR , Matthias JOHN , Atanu ROY , Susan WHORISKEY , Kristy M. WOOD , Paul HATALA , Jason P. SCHRUM , Kenechi EJEBE , Jeff Lynn ELLSWORTH , Justin GUILD
IPC: A61K48/00 , A61K9/127 , C12P21/00 , C12P13/04 , C12N15/87 , C12N15/85 , C12N15/52 , C12N15/11 , C12N9/00 , C12N9/88 , C12N9/64 , C12N9/42 , C12N9/24 , C12N9/16 , C12N9/10 , C07K16/00 , C07K14/705 , C07K14/62 , C07K14/56 , C07K14/535 , C07K14/525 , C07K14/515 , C07K14/505 , A61K47/54 , C07K14/47 , C07K14/435 , C07K14/005 , A61K38/48 , A61K38/45 , A61K38/21 , A61K38/19 , A61K38/18 , A61K38/17 , A61K31/7115 , A61K9/51 , A61K9/14 , C07K14/485 , A61K38/00
Abstract: The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides, primary transcripts and mmRNA molecules.
-
公开(公告)号：US20210115101A1
公开(公告)日：2021-04-22
申请号：US16665985
申请日：2019-10-28
Applicant: ModernaTX, Inc.
Inventor： Stephane BANCEL , Tirtha CHAKRABORTY , Antonin DE FOUGEROLLES , Sayda M. ELBASHIR , Matthias JOHN , Atanu ROY , Susan WHORISKEY , Kristy M. WOOD , Paul HATALA , Jason P. SCHRUM , Kenechi EJEBE , Jeff Lynn ELLSWORTH , Justin GUILD
IPC: C07K14/535 , A61K48/00 , A61K47/54 , C12N15/88 , A61K9/127 , A61K9/50 , C07K14/47 , A61K31/7088 , C07K19/00 , C12N15/85 , A61K38/18 , A61K38/19 , A61K38/48 , A61K9/14 , A61K38/17 , A61K47/10 , A61K38/21 , A61K38/36 , A61K38/44 , A61K39/395 , C07K14/475 , C07K14/505 , C07K14/525 , C07K14/56 , C07K14/565 , C07K14/745 , C07K14/75 , C07K16/28 , C07K16/32 , C12N9/02 , C12N9/64
Abstract: The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides, primary transcripts and mmRNA molecules.
-
5.发明申请公开(公告)号：US20180311381A1
公开(公告)日：2018-11-01
申请号：US15790246
申请日：2017-10-23
Applicant: ModernaTX, Inc.
Inventor： Stephane BANCEL , Tirtha CHAKRABORTY , Antonin DE FOUGEROLLES , Sayda M. ELBASHIR , Matthias JOHN , Atanu ROY , Susan WHORISKEY , Kristy M. WOOD , Paul HATALA , Jason P. SCHRUM , Kenechi EJEBE , Jeff Lynn ELLSWORTH , Justin GUILD
IPC: A61K48/00 , C12P21/00 , C12P13/04 , C12N15/87 , C12N15/85 , C12N15/52 , C12N15/11 , C12N9/00 , C12N9/88 , C12N9/64 , C12N9/68 , C12N9/42 , C12N9/24 , C12N9/16 , C12N9/12 , C12N9/10 , C12N9/02 , C07K16/40 , C07K16/28 , C07K16/00 , C07K14/745 , C07K14/705 , C07K14/62 , C07K14/61 , C07K14/56 , C07K14/54 , C07K14/535 , C07K14/525 , C07K14/515 , C07K14/505 , C07K14/495 , C07K14/485 , C07K14/475 , C07K14/47 , C07K14/435 , C07K14/005 , C07H21/02 , A61K38/48 , A61K38/45 , A61K38/21 , A61K38/19 , A61K38/18 , A61K38/17 , A61K31/7115 , A61K9/51 , A61K9/14 , A61K9/127 , A61K47/54 , A61K38/00
Abstract: The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides, primary transcripts and mmRNA molecules.
-
Patent Agency Ranking
公开(公告)号：US20180170990A1
公开(公告)日：2018-06-21
申请号：US15662090
申请日：2017-07-27
Applicant: ModernaTX, Inc.
Inventor： Stephane BANCEL , Tirtha CHAKRABORTY , Antonin DE FOUGEROLLES , Sayda M. ELBASHIR , Matthias JOHN , Atanu ROY , Susan WHORISKEY , Paul HATALA , Jason P. SCHRUM , Kenechi EJEBE , Jeff Lynn ELLSWORTH , Justin GUILD , Ron WEISS , Kristy M. WOOD
IPC: C07K14/535 , A61K48/00 , C07K14/745 , C07K16/28 , C07K16/32 , C12N9/02 , C12N9/64 , A61K38/19 , A61K38/21 , A61K38/36 , A61K38/44 , A61K38/48 , A61K39/395 , C07K14/475 , C07K14/505 , C07K14/525 , C07K14/56 , C07K14/565 , C07K14/75 , A61K47/10 , A61K38/18 , A61K38/17 , A61K9/14 , C07K14/47 , C12N15/85 , A61K9/50 , A61K9/127
CPC classification number: C07K14/535 , A61K9/0019 , A61K9/1271 , A61K9/1272 , A61K9/1277 , A61K9/14 , A61K9/5031 , A61K31/7088 , A61K38/1767 , A61K38/1816 , A61K38/1866 , A61K38/191 , A61K38/193 , A61K38/212 , A61K38/215 , A61K38/36 , A61K38/363 , A61K38/44 , A61K38/4833 , A61K38/4846 , A61K39/3955 , A61K47/10 , A61K47/54 , A61K47/542 , A61K48/00 , A61K48/0033 , A61K48/0066 , A61K48/0075 , C07K14/47 , C07K14/475 , C07K14/505 , C07K14/525 , C07K14/56 , C07K14/565 , C07K14/745 , C07K14/75 , C07K16/2887 , C07K16/32 , C07K19/00 , C12N9/0069 , C12N9/644 , C12N15/85 , C12N15/88 , C12N2840/00 , C12Y113/12007 , C12Y304/21005 , C12Y304/21022
Abstract: The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides, primary transcripts and mmRNA molecules.
-
公开(公告)号：US20220273555A1
公开(公告)日：2022-09-01
申请号：US16860121
申请日：2020-04-28
Applicant: ModernaTX, Inc.
Inventor： Stephane BANCEL , Tirtha CHAKRABORTY , Antonin DE FOUGEROLLES , Sayda M. ELBASHIR , Matthias JOHN , Atanu ROY , Susan WHORISKEY , Kristy M. WOOD , Paul HATALA , Jason P. SCHRUM , Kenechi EJEBE , Jeff Lynn ELLSWORTH , Justin GUILD
Abstract: The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides, primary transcripts and mmRNA molecules.
-
公开(公告)号：US20190240351A1
公开(公告)日：2019-08-08
申请号：US15789138
申请日：2017-10-20
Applicant: ModernaTX, Inc.
Inventor： Stephane BANCEL , Tirtha CHAKRABORTY , Antonin DE FOUGEROLLES , Sayda M. ELBASHIR , Jeff Lynn ELLSWORTH , Kenechi EJEBE , Justin GUILD , Matthias JOHN , Paul HATALA , Atanu ROY , Jason P. SCHRUM , Susan WHORISKEY , Kristy M. WOOD
IPC: A61K48/00 , C07K14/535 , C07K14/47 , C07K14/515 , A61K9/127 , C12N9/64 , A61K31/7115 , A61K47/54 , A61K9/51 , A61K9/14 , C12N15/87 , C12N15/85 , C12N9/00 , C07K14/705 , C07K14/62 , C07K14/505 , C07K14/485 , C07K14/435 , A61K38/45 , A61K38/17 , A61K38/48 , C07K14/525 , C07K14/56 , C07K16/00 , C12P21/00 , A61K38/18 , A61K38/19 , A61K38/21 , C12P13/04 , C12N15/52 , C12N15/11 , C12N9/88 , C12N9/42 , C12N9/24 , C12N9/16 , C12N9/10 , C07K14/005
CPC classification number: A61K48/0066 , A61K9/1271 , A61K9/145 , A61K9/5123 , A61K9/5146 , A61K9/5153 , A61K31/7115 , A61K38/00 , A61K38/17 , A61K38/177 , A61K38/1816 , A61K38/1891 , A61K38/191 , A61K38/193 , A61K38/212 , A61K38/45 , A61K38/4846 , A61K47/543 , A61K48/0033 , A61K48/005 , A61K48/0075 , C07H21/02 , C07K14/005 , C07K14/435 , C07K14/43595 , C07K14/47 , C07K14/4705 , C07K14/4713 , C07K14/4723 , C07K14/4746 , C07K14/475 , C07K14/485 , C07K14/495 , C07K14/505 , C07K14/515 , C07K14/525 , C07K14/535 , C07K14/5418 , C07K14/56 , C07K14/61 , C07K14/62 , C07K14/705 , C07K14/745 , C07K16/00 , C07K16/2863 , C07K16/2887 , C07K16/40 , C12N9/0069 , C12N9/0091 , C12N9/1051 , C12N9/1241 , C12N9/16 , C12N9/2402 , C12N9/2445 , C12N9/6435 , C12N9/6437 , C12N9/644 , C12N9/6443 , C12N9/6451 , C12N9/88 , C12N9/93 , C12N15/11 , C12N15/52 , C12N15/85 , C12N15/87 , C12P13/04 , C12P21/00 , C12P21/005 , C12Y113/12007 , C12Y116/03001 , C12Y207/07012 , C12Y304/21007 , C12Y304/21022 , C12Y304/21027 , C12Y403/02001 , C12Y603/02019 , Y02A50/401 , Y02A50/411 , Y02A50/414 , Y02A50/415 , Y02A50/423 , Y02A50/463 , Y02A50/491
Abstract: The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides, primary transcripts and mmRNA molecules.
-
公开(公告)号：US20180086807A1
公开(公告)日：2018-03-29
申请号：US15440523
申请日：2017-02-23
Applicant: ModernaTX, Inc.
Inventor： Stephane BANCEL , Tirtha CHAKRABORTY , Antonin DE FOUGEROLLES , Sayda M. ELBASHIR , Matthias JOHN , Atanu ROY , Susan WHORISKEY , Kristy M. WOOD , Paul HATALA , Jason P. SCHRUM , Kenechi EJEBE , Jeff Lynn ELLSWORTH , Justin GUILD
IPC: C07K14/535 , A61K9/127 , C12N15/88 , C12N15/85 , C12N9/64 , C12N9/02 , C07K19/00 , C07K16/32 , C07K16/28 , C07K14/75 , C07K14/745 , C07K14/565 , C07K14/56 , C07K14/525 , C07K14/505 , C07K14/475 , C07K14/47 , A61K48/00 , A61K47/10 , A61K39/395 , A61K38/48 , A61K38/44 , A61K38/36 , A61K38/21 , A61K38/19 , A61K38/18 , A61K38/17 , A61K31/7088 , A61K9/50 , A61K9/14 , A61K9/00
CPC classification number: C07K14/535 , A61K9/0019 , A61K9/1271 , A61K9/1272 , A61K9/1277 , A61K9/14 , A61K9/5031 , A61K31/7088 , A61K38/1767 , A61K38/1816 , A61K38/1866 , A61K38/191 , A61K38/193 , A61K38/212 , A61K38/215 , A61K38/36 , A61K38/363 , A61K38/44 , A61K38/4833 , A61K38/4846 , A61K39/3955 , A61K47/10 , A61K47/54 , A61K47/542 , A61K48/00 , A61K48/0033 , A61K48/0066 , A61K48/0075 , C07K14/47 , C07K14/475 , C07K14/505 , C07K14/525 , C07K14/56 , C07K14/565 , C07K14/745 , C07K14/75 , C07K16/2887 , C07K16/32 , C07K19/00 , C12N9/0069 , C12N9/644 , C12N15/85 , C12N15/88 , C12N2840/00 , C12Y113/12007 , C12Y304/21005 , C12Y304/21022
Abstract: The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of polynucleotides, primary transcripts and mmRNA molecules.
-
10.发明申请公开(公告)号：US20180002393A1
公开(公告)日：2018-01-04
申请号：US15425813
申请日：2017-02-06
Applicant: ModernaTX, Inc.
Inventor： Stephane BANCEL , Tirtha CHAKRABORTY , Antonin DE FOUGEROLLES , Sayda M. ELBASHIR , Matthias JOHN , Atanu ROY , Susan WHORISKEY , Kristy M. WOOD , Paul HATALA , Jason P. SCHRUM , Kenechi EJEBE , Jeff Lynn ELLSWORTH , Justin GUILD
IPC: C07K14/535 , C12N15/88 , C12N15/85 , C12N9/64 , C12N9/02 , C07K19/00 , C07K16/32 , C07K16/28 , C07K14/75 , C07K14/745 , C07K14/565 , C07K14/56 , C07K14/525 , C07K14/505 , C07K14/475 , C07K14/47 , A61K48/00 , A61K47/60 , A61K47/10 , A61K39/395 , A61K38/48 , A61K38/44 , A61K38/36 , A61K38/21 , A61K38/19 , A61K38/18 , A61K38/17 , A61K31/7088 , A61K9/50 , A61K9/14 , A61K9/127 , A61K9/00
CPC classification number: C07K14/535 , A61K9/0019 , A61K9/0043 , A61K9/1271 , A61K9/1272 , A61K9/1277 , A61K9/14 , A61K9/145 , A61K9/5031 , A61K31/7088 , A61K31/7115 , A61K38/1767 , A61K38/1816 , A61K38/1866 , A61K38/191 , A61K38/193 , A61K38/212 , A61K38/215 , A61K38/36 , A61K38/363 , A61K38/44 , A61K38/4833 , A61K38/4846 , A61K39/3955 , A61K47/10 , A61K47/60 , A61K48/00 , A61K48/0033 , A61K48/0066 , A61K48/0075 , C07K14/47 , C07K14/475 , C07K14/505 , C07K14/525 , C07K14/56 , C07K14/565 , C07K14/745 , C07K14/75 , C07K16/2887 , C07K16/32 , C07K19/00 , C12N9/0069 , C12N9/644 , C12N15/85 , C12N15/88 , C12N2840/00 , C12Y113/12007 , C12Y304/21005 , C12Y304/21022 , A61K2300/00
Abstract: The invention relates to compositions and methods for the preparation, manufacture and therapeutic use of oncology-related polynucleotides, oncology-related primary transcripts and oncology-related mmRNA molecules.
-
-
-
-
-
-
-
-
-
Search Results
11
records
(took 0.072 seconds)
