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    System and methods for image-guided thermal treatment of tissue
    1.
    发明申请
    System and methods for image-guided thermal treatment of tissue 有权
    图像引导热处理组织的系统和方法

    公开(公告)号：US20060184163A1

    公开(公告)日：2006-08-17

    申请号：US11058882

    申请日：2005-02-16

    Applicant: Michael Breen ,  David Wilson ,  Gerald Saidel

    Inventor： Michael Breen ,  David Wilson ,  Gerald Saidel

    IPC: A61B18/18 ,  A61B18/04

    CPC classification number: A61B18/04 ,  A61B18/14 ,  A61B18/20 ,  A61B2017/00084 ,  A61B2017/00716 ,  A61B2090/374 ,  A61B2090/376 ,  A61N7/02

    Abstract: A system and methods for modeling the death of tissue cells that are thermally treated using thermal treatment devices is disclosed. A cell-death model accurately predicts, in real-time, which voxels of cells are dead or are about to die as the thermal treatment is applied to these cells. The effects of thermal treatment are monitored by a thermal measurement device which feeds thermal information to the cell-death model. The cell-death model accounts for the temperature of each voxel of tissue cells with respect to a temperature threshold value and the duration over which the thermal treatment is applied. When the thermal measurement device is an imaging device, the results of the thermal treatment may be displayed to the user in real-time. As a result, a user of the thermal treatment device can determine, in real-time, which target voxels of cells he has killed and which still need to be killed. The user can also more easily avoid inadvertently killing healthy tissue that he does not intend to kill. The cell-death model may be implemented in software on the thermal measurement device, on the thermal treatment device, or on a separate processing device which interfaces to and communicates with at least one of the thermal measurement device and the thermal treatment device.

    Abstract translation: 公开了一种使用热处理装置进行热处理来建模组织细胞死亡的系统和方法。 细胞死亡模型实时准确地预测，当将热处理应用于这些细胞时，细胞的体素死亡或将要死亡。 通过热测量装置监测热处理的效果，热测量装置将热信息馈送到细胞死亡模型。 细胞死亡模型考虑了温度阈值和施加热处理的持续时间的组织细胞的每个体素的温度。 当热测量装置是成像装置时，热处理的结果可以实时显示给用户。 结果，热处理装置的用户可以实时地确定他已经杀死并且仍然需要杀死的细胞的哪些目标体素。 用户也可以更容易地避免无意中杀死他不打算杀死的健康组织。 细胞死亡模型可以在热测量装置，热处理装置上的软件中或者与热测量装置和热处理装置中的至少一个相接口并与之通信的单独的处理装置上实现。

    Imaging system
    2.
    发明申请
    Imaging system 有权
    成像系统

    公开(公告)号：US20070091428A1

    公开(公告)日：2007-04-26

    申请号：US11581995

    申请日：2006-10-17

    Applicant: David Wilson ,  Debashish Roy ,  Michael Breen

    Inventor： David Wilson ,  Debashish Roy ,  Michael Breen

    IPC: G02B21/26

    CPC classification number: G02B21/365

    Abstract: Systems, methods, media, and other embodiments associated with episcopic, histological, autoradiographic, and/or other imaging are described. One exemplary system includes a cryomicrotome, an episcopic imaging device and a histological imaging device, logic for registering episcopic images with histological images, and logic for manipulating images acquired from the episcopic imaging device and the histological imaging device.

    Abstract translation: 描述与异位，组织学，放射自显影和/或其他成像相关联的系统，方法，介质和其它实施方案。 一个示例性系统包括冷冻切片机，显影成像装置和组织学成像装置，用于用异物成像装置和组织学成像装置获取的图像的用于记录具有组织学图像的异象图像的逻辑和逻辑。

    SURGICAL TOOL
    4.
    发明申请
    SURGICAL TOOL 有权
    手术工具

    公开(公告)号：US20170014131A1

    公开(公告)日：2017-01-19

    申请号：US14934878

    申请日：2015-11-06

    Applicant: Keith Edward Martin ,  Frank M. Fago ,  David Wilson

    Inventor： Keith Edward Martin ,  Frank M. Fago ,  David Wilson

    IPC: A61B17/10

    CPC classification number: A61B17/1285 ,  A61B17/00234 ,  A61B17/10 ,  A61B17/1227 ,  A61B34/71 ,  A61B2017/00243 ,  A61B2017/00323 ,  A61B2017/00584 ,  A61B2017/0069 ,  A61B2017/2902 ,  A61B2017/2927 ,  A61B2017/2937 ,  A61B2017/2939

    Abstract: A medical instrument including a first joint including a first member and a second member, the first member configured to be repositionable with respect to the second member in a first degree of freedom, a second joint operatively coupled to the first joint, the second joint including a third member and a fourth member, the third member configured to be repositionable with respect to the fourth member in a second degree of freedom, a pair of repositionable jaws operatively coupled to the first joint and the second joint, an open-ended occlusion clip detachably mounted to the pair of repositionable jaws, and a controller operatively coupled to the first joint, the second joint, and the pair of repositionable jaws, the controller including a control with a line operatively coupled to the first and second jaws in at least a gun tackle pulley configuration.

    Abstract translation: 一种医疗器械，包括包括第一构件和第二构件的第一接头，所述第一构件被构造成在第一自由度中可相对于所述第二构件重新定位，第二接头可操作地联接到所述第一接头，所述第二接头包括 第三构件和第四构件，所述第三构件被构造成能够以第二自由度相对于所述第四构件重新定位，可操作地联接到所述第一接头和所述第二接头的一对可重定位爪，开口闭塞夹 可拆卸地安装到一对可重定位爪上，以及控制器，其可操作地联接到第一接头，第二接头和一对可重定位爪，控制器包括控制器，该控制器具有可操作地连接到第一和第二钳口的至少一个 枪滑轮配置。

    Automated laboratory system
    6.
    发明授权
    Automated laboratory system 有权
    自动化实验室系统

    公开(公告)号：US08865474B2

    公开(公告)日：2014-10-21

    申请号：US11429888

    申请日：2006-05-08

    Applicant: Michael Paschetto ,  Peter Massaro ,  Jeff Boot ,  David Wilson

    Inventor： Michael Paschetto ,  Peter Massaro ,  Jeff Boot ,  David Wilson

    IPC: G01N33/559 ,  G01N35/00 ,  G01N27/447 ,  B01L3/02 ,  G01N35/04

    CPC classification number: G01N35/0099 ,  B01L3/0244 ,  B01L3/0275 ,  G01N27/44704 ,  G01N27/44743 ,  G01N27/44747 ,  G01N27/44782 ,  G01N35/04 ,  Y10T436/25375

    Abstract: An automated laboratory system and method allow high-throughput and fully automated processing of materials, such as liquids including genetic materials. The invention includes a variety of aspects that may be combined into a single system. For example, processing may be performed by a plurality of robotic-equipped modular stations, where each modular station has its own unique environment in which processes are performed. Transport devices, such as conveyor belts, may move objects between modular stations, saving movement for robots in the modular stations. Gels used for gel electrophoresis may be extruded, thus decreasing the time needed to form such gels. Robotically-operated well forming tools allow wells to be formed in gels in a registered and accurate way.

    Abstract translation: 自动化实验室系统和方法允许对诸如包括遗传物质在内的液体进行高通量和全自动化处理。 本发明包括可以组合成单个系统的各种方面。 例如，处理可以由多个装有机器人的模块化站来执行，其中每个模块站具有其自己的执行过程的独特环境。 诸如传送带之类的运输设备可以在模块化站之间移动物体，从而节省模块化站中机器人的运动。 可以挤出用于凝胶电泳的凝胶，从而减少形成这种凝胶所需的时间。 机器人操作的成型工具允许以注册和准确的方式在凝胶中形成孔。

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