公开(公告)号：USD1012094S1

公开(公告)日：2024-01-23

申请号：US29764515

申请日：2020-12-30

Applicant: Meso Scale Technologies, LLC.

Designer： Eli N. Glezer ,  Michael L. Vock ,  Kent Johnson

Abstract: FIG. 1 is a front view of a display panel or screen with a graphical user interface showing the first embodiment of our novel design;
FIG. 2 is a second embodiment thereof;
FIG. 3 is a third embodiment thereof;
FIG. 4 is a fourth embodiment thereof;
FIG. 5 is a fifth embodiment thereof;
FIG. 6 is a sixth embodiment thereof;
FIG. 7 is a seventh embodiment thereof;
FIG. 8 is an eighth embodiment thereof; and,
FIG. 9 is a ninth embodiment thereof.
The broken line showing of the display panel or screen and portions of the graphical user interface form no part of the claimed design.

公开(公告)号：USRE49774E1

公开(公告)日：2024-01-02

申请号：US17173898

申请日：2021-02-11

Applicant: Meso Scale Technologies, LLC.

Inventor： Eli N. Glezer ,  Sudeep Kumar ,  Pankaj Oberoi ,  George Sigal ,  Michael Tsionsky

IPC: C12Q1/68 ,  B01L3/00 ,  C12Q1/6804 ,  C12Q1/6816 ,  C12Q1/6876 ,  G01N33/543 ,  G01N33/68

CPC classification number: B01L3/50853 ,  C12Q1/6804 ,  C12Q1/6816 ,  C12Q1/6876 ,  G01N33/54306 ,  G01N33/54353 ,  G01N33/6845 ,  B01L2300/021 ,  B01L2300/043 ,  B01L2300/0609 ,  B01L2300/0829 ,  G01N2458/10 ,  C12Q1/6816 ,  C12Q2563/131

Abstract: The invention relates to methods for conducting solid-phase binding assays. One example is an assay method having improved analyte specificity where specificity is limited by the presence of non-specific binding interactions.

公开(公告)号：US11697840B2

公开(公告)日：2023-07-11

申请号：US16136498

申请日：2018-09-20

Applicant: Meso Scale Technologies, LLC.

Inventor： Eli N. Glezer ,  John Kenten

IPC: C12Q1/6844 ,  G01N33/543 ,  C12Q1/682 ,  C12Q1/6837 ,  C12Q1/6848 ,  C12Q1/6804 ,  G01N33/542

CPC classification number: C12Q1/6844 ,  C12Q1/682 ,  C12Q1/6804 ,  C12Q1/6837 ,  C12Q1/6848 ,  G01N33/542 ,  G01N33/54306 ,  C12Q2531/125 ,  C12Q2533/107 ,  G01N2458/10 ,  C12Q1/6848 ,  C12Q2531/125 ,  C12Q2565/549 ,  C12Q1/6804 ,  C12Q2531/125 ,  C12Q2533/107 ,  C12Q2565/401 ,  C12Q2565/519

Abstract: The present invention is directed to improved methods for conducting immunoassays. The methods are designed to amplify signals in immunoassays and anchor immunoassay complexes employed therein.

公开(公告)号：US11148145B2

公开(公告)日：2021-10-19

申请号：US16210165

申请日：2018-12-05

Applicant: Meso Scale Technologies, LLC

Inventor： Eli N. Glezer ,  Sudeep Kumar ,  Pankaj Oberoi ,  George Sigal ,  Michael Tsionsky

IPC: C12Q1/68 ,  B01L3/00 ,  C12Q1/6876 ,  G01N33/543 ,  C12Q1/6816 ,  C12Q1/6804 ,  G01N33/68

Abstract: The invention relates to methods for conducting solid-phase binding assays. One example is an assay method having improved analyte specificity where specificity is limited by the presence of non-specific binding interactions.

公开(公告)号：US10935547B2

公开(公告)日：2021-03-02

申请号：US15222674

申请日：2016-07-28

Applicant: Meso Scale Technologies, LLC.

Inventor： Eli N. Glezer ,  Jonathan K. Leland ,  Mark A. Billadeau ,  Joseph M. Leginus ,  Bandele Jeffrey-Coker ,  Jeffery D. Debad ,  Koustubh A. Phalnikar ,  Sriram Jambunathan

IPC: G01N33/543 ,  B01L3/00 ,  B01L9/00 ,  C12Q1/00 ,  G01N27/30 ,  G01N21/76 ,  B01J19/00 ,  B33Y80/00 ,  C40B40/10

Abstract: Assay modules, preferably assay cartridges, are described as are reader apparatuses which may be used to control aspects of module operation. The modules preferably comprise a detection chamber with integrated electrodes that may be used for carrying out electrode induced luminescence measurements. Methods are described for immobilizing assay reagents in a controlled fashion on these electrodes and other surfaces. Assay modules and cartridges are also described that have a detection chamber, preferably having integrated electrodes, and other fluidic components which may include sample chambers, waste chambers, conduits, vents, bubble traps, reagent chambers, dry reagent pill zones and the like. In certain preferred embodiments, these modules are adapted to receive and analyze a sample collected on an applicator stick.

公开(公告)号：US10725059B2

公开(公告)日：2020-07-28

申请号：US15564581

申请日：2016-04-06

Applicant: Meso Scale Technologies, LLC

Inventor： Eli N. Glezer ,  Carl Edens ,  Bandele Jeffrey-Coker ,  Sandor Kovacs ,  Christopher Frye

IPC: G01N35/00 ,  B01F11/00 ,  G01N35/10 ,  G01N33/543 ,  B06B1/16

Abstract: The present invention relates to a system for performing assays on a solid phase to measure the level of analyte in a sample. Such a system may perform immunoassays using electrochemiluminescence (ECL) including a counterbalanced orbital shaking apparatus for assay consumables.

公开(公告)号：US20190391140A1

公开(公告)日：2019-12-26

申请号：US16564208

申请日：2019-09-09

Applicant: MESO SCALE TECHNOLOGIES, LLC.

Inventor： Anahit Aghvanyan ,  Eli N. Glezer ,  John Kenten ,  George Sigal ,  Martin Stengelin ,  David Routenberg

IPC: G01N33/543 ,  C12Q1/6844 ,  C12Q1/6837 ,  C12Q1/6832

Abstract: The present invention is directed to methods for improving assay specificity and performance in binding assays.

公开(公告)号：US10436784B2

公开(公告)日：2019-10-08

申请号：US14854514

申请日：2015-09-15

Applicant: Meso Scale Technologies, LLC ,  The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc.

Inventor： William F Blakely ,  Eli N. Glezer ,  John Kenten ,  Sudeep Kumar ,  Anu Mathew ,  Natalia I. Ossetrova ,  George Sigal

IPC: G01N33/53 ,  G01N33/569 ,  G01N33/68 ,  G01N33/566

Abstract: The present invention relates to methods and kits to assess an absorbed dose of ionizing radiation and/or the severity of tissue injury from radiation in a patient. The invention also relates to algorithms used to calculate an absorbed dose of radiation based on biomarker measurements of a plurality of biomarkers that are altered relative to a normal control in the event of radiation exposure.

公开(公告)号：US20190178787A1

公开(公告)日：2019-06-13

申请号：US16219030

申请日：2018-12-13

Applicant: Meso Scale Technologies, LLC

Inventor： Nicholas Anderson ,  Jeffery Debad ,  Eli N. Glezer ,  Sudeep Kumar ,  Noel Lawrence ,  Kenneth Page ,  George Sigal ,  Sharon West

IPC: G01N21/05 ,  G01N21/03 ,  G01N21/69 ,  G01N21/76 ,  G01F23/02 ,  G01F23/292 ,  B01L3/00

Abstract: Assay cartridges are described that have a detection chamber, preferably having integrated electrodes, and other fluidic components which may include sample chambers, waste chambers, conduits, vents, bubble traps, reagent chambers, dry reagent pill zones and the like. In certain embodiments, these cartridges are adapted to receive and analyze a sample collected on an applicator stick. Also described are kits including such cartridges and a cartridge reader configured to analyze an assay conducted using an assay cartridge.

公开(公告)号：US10281678B2

公开(公告)日：2019-05-07

申请号：US14147216

申请日：2014-01-03

Applicant: Meso Scale Technologies, LLC

Inventor： Ian Chamberlin ,  Charles M. Clinton ,  Eli N. Glezer ,  Bandele Jeffrey-Coker ,  Manish Kochar ,  Sandor Kovacs ,  D. T. Le ,  Aaron Leimkuehler ,  George Sigal ,  Leo Tabakin ,  Jon Willoughby

IPC: G02B7/36 ,  G01N35/02 ,  G01N21/25 ,  G01N21/64

Abstract: Apparatuses, systems, method, reagents, and kits for conducting assays as well as process for their preparation are described. They are particularly well suited for conducting automated analysis in a multi-well plate assay format.