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公开(公告)号：US11749437B2
公开(公告)日：2023-09-05
申请号：US16400840
申请日：2019-05-01
CPC分类号： H01F7/14 , B01L3/50273 , B01L3/502707 , B01L3/502715 , B01L3/502753 , B01L9/527 , C12M21/08 , C12M23/16 , C12M29/00 , F04B43/043 , F04B43/14 , B01L2200/025 , B01L2200/027 , B01L2200/10 , B01L2300/123 , B01L2400/043 , B01L2400/0415
摘要： On-platform pumps provide greater flexibility and design freedom and are a key feature of organs-on-chip platforms. On-platform electromagnetic (EM) pumps have been developed for use with the organ-on-chip platforms. The EM pump uses electrical energy, which may be supplied by a battery, making the pump portable. The EM pump uses an EM actuator having a low energy consumption. The actuator's low energy consumption is achieved by a latching design which requires only a short pulse of energy to switch its state and where springs store some of the actuator kinetic energy, which is then recovered in the reverse stroke. This further reduces the energy consumption of the actuator. Also provided are injection-molded, single-use platforms with onboard diaphragm micro-pumps and various valve and pump geometries. The EM actuators easily integrate with these platforms, demonstrating pumping at a constant flowrate, no measurable temperature rise, and valve sealing against varying back-pressure.
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公开(公告)号：US10833570B2
公开(公告)日：2020-11-10
申请号：US16204042
申请日：2018-11-29
发明人： Minkyun Noh , David L. Trumper
摘要： Described are homopolar bearingless slice motors which include an array arrangement of permanent magnets on stator teeth, and a magnet-free rotor having a unique surface geometry. Also described are related components of such motors. The permanent magnet arrays provide homopolar bias flux to the rotor, and salient features on the rotor surface route the bias flux toward paths desirable for force and torque generation. In an illustrative embodiment, two magnet arrays are placed at the tips of stator teeth, so as to provide the bias flux via relatively short flux paths. By modulating current through windings based upon the rotor radial and angular position measurements, the stator can levitate and rotate the rotor.
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3.发明授权System and method for providing electromagnetic imaging through magnetoquasistatic sensing 有权通过磁静电感测提供电磁成像的系统和方法公开(公告)号：US08742770B2
公开(公告)日：2014-06-03
申请号：US13912374
申请日：2013-06-07
IPC分类号： G01B7/00
摘要： A system for providing electromagnetic imaging through magnetoquasistatic sensing contains an electromagnetic sensor for imaging a sample. The electromagnetic sensor contains drive/sense electronics and a pixelated sensor array having an array of inductive loops that source magnetic fields that interact with the sample, wherein the inductive loops are individually drivable by the drive/sense electronics in a coordinated manner to establish a desired temporal and spatial pattern in which electrical properties of the inductive loops are used to generate an image. Other components of the system include a precision motion controller, sensor head and associated electronics, and a computer for performing data acquisition and signal inversion.
摘要翻译： 用于通过磁静电检测提供电磁成像的系统包含用于对样品进行成像的电磁传感器。 电磁传感器包含驱动/感测电子器件和具有感应回路阵列的像素化传感器阵列，其感应回路源于与样品相互作用的磁场，其中感应回路可由驱动/感测电子器件以协调的方式独立地驱动，以建立所需的 时间和空间模式，其中感应回路的电气特性用于产生图像。 该系统的其他部件包括精密运动控制器，传感头和相关的电子设备，以及用于执行数据采集和信号反转的计算机。
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4.发明申请SYSTEM AND METHOD FOR PROVIDING ELECTROMAGNETIC IMAGING THROUGH MAGNETOQUASISTATIC SENSING 有权通过磁感测传感器提供电磁成像的系统和方法公开(公告)号：US20130271123A1
公开(公告)日：2013-10-17
申请号：US13912374
申请日：2013-06-07
IPC分类号： G01N27/72
摘要： A system for providing electromagnetic imaging through magnetoquasistatic sensing contains an electromagnetic sensor for imaging a sample. The electromagnetic sensor contains drive/sense electronics and a pixelated sensor array having an array of inductive loops that source magnetic fields that interact with the sample, wherein the inductive loops are individually drivable by the drive/sense electronics in a coordinated manner to establish a desired temporal and spatial pattern in which electrical properties of the inductive loops are used to generate an image. Other components of the system include a precision motion controller, sensor head and associated electronics, and a computer for performing data acquisition and signal inversion.
摘要翻译： 用于通过磁静电检测提供电磁成像的系统包含用于对样品进行成像的电磁传感器。 电磁传感器包含驱动/感测电子器件和具有感应回路阵列的像素化传感器阵列，其感应回路源于与样品相互作用的磁场，其中感应回路可以由驱动/感测电子器件以协调的方式单独驱动以建立所需的 时间和空间模式，其中感应回路的电气特性用于产生图像。 该系统的其他部件包括精密运动控制器，传感头和相关的电子设备，以及用于执行数据采集和信号反转的计算机。
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公开(公告)号：US20130174300A1
公开(公告)日：2013-07-04
申请号：US13716814
申请日：2012-12-17
发明人： David L. Trumper , Ian MacKenzie
IPC分类号： G01Q30/00
摘要： A system contains a first actuator half containing a first pair of actuator coils and a second pair of actuator coils located above the first pair of actuator coils, wherein the first pair of actuator coils is connected to a first metallic backing. A second actuator half is also providing within the system, which contains a first pair of actuator coils and a second pair of actuator coils located above the first pair of actuator coils, wherein the first pair of actuator coils is connected to a second metallic backing. The system also contains a mechanical flexure suspension having at least one flexure supporting a permanent magnet that is capable of moving, wherein the mechanical flexure suspension is located between the first actuator half and the second actuator half.
摘要翻译： 系统包括第一致动器半部，其包含第一对致动器线圈和位于第一对致动器线圈上方的第二对致动器线圈，其中第一对致动器线圈连接到第一金属背衬。 第二致动器半部还在系统内提供，其包含第一对致动器线圈和位于第一对致动器线圈上方的第二对致动器线圈，其中第一对致动器线圈连接到第二金属背衬。 该系统还包含机械挠曲悬架，其具有至少一个支撑能够移动的永磁体的挠曲件，其中机械挠曲悬架位于第一致动器半部和第二致动器半部之间。
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公开(公告)号：US12065635B2
公开(公告)日：2024-08-20
申请号：US16358137
申请日：2019-03-19
IPC分类号： C12M1/00 , B01L3/00 , C12M1/02 , C12M1/12 , C12M1/32 , C12M1/34 , C12M3/00 , C12M3/06 , C12N5/071 , G01N33/50
CPC分类号： C12M29/24 , B01L3/50273 , C12M21/08 , C12M23/12 , C12M23/16 , C12M23/44 , C12M23/46 , C12M25/06 , C12M25/14 , C12M27/00 , C12M27/18 , C12M41/34 , C12N5/0671 , C12N5/0697 , G01N33/5008 , G01N33/5088 , B01L2300/0829 , B01L2300/0858 , B01L2300/10
摘要： Organ-on-chip platforms with reduced fluid volumes include circulating fluid volumes of below 1000 μL, preferably about 500 μL or less. The platforms are adjustable for culturing cells with varied oxygen demand at various seeding densities. The platforms include at least one lane, wherein each lane includes at least one cell culture well, at least one oxygenator for fluid oxygenation, and a pump system containing at least one pump per lane. The oxygenator may include a separate fluid path for oxygenating the fluid, which allows controlling and measuring the oxygen concentration in the fluid, shortening the diffusion length, and passively diffusing oxygen. Provided are also different configurations for the oxygenator, fluid circulation in the platforms, attachment means for securing scaffolds to culture wells, and pneumatic plates.
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公开(公告)号：US20240195276A1
公开(公告)日：2024-06-13
申请号：US18530495
申请日：2023-12-06
发明人： Krishan Kant , David L. Trumper
IPC分类号： H02K21/40 , A61M60/109 , A61M60/216 , A61M60/422 , F04D7/00 , F04D13/06 , H02K1/17 , H02K1/24
CPC分类号： H02K21/40 , A61M60/109 , A61M60/216 , A61M60/422 , F04D7/00 , F04D13/06 , H02K1/17 , H02K1/246
摘要： A bearingless split tooth flux-reversal motor (FRM) for use with a pump, such as a centrifugal blood pump. In some embodiments, the motor has a magnet-free rotor and a magnetic configuration wherein the force generation is independent of the rotor angle, allowing for simple radial force generation using stator-fixed currents. The motor torque can be generated using commutated two-phase currents.
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公开(公告)号：US20230395409A1
公开(公告)日：2023-12-07
申请号：US18248474
申请日：2021-11-12
IPC分类号： H01L21/67 , H01L21/68 , H01L21/683 , B65G47/92 , G03F7/00
CPC分类号： H01L21/67259 , H01L21/68 , H01L21/6833 , B65G47/92 , G03F7/70708 , G03F7/70741
摘要： An electrostatic chuck includes electrodes to clamp a workpiece, electrodes to electrostatically levitate and position the workpiece, and sensors to detect position and orientation of the workpiece. Lateral motion of the workpiece relative to the electrostatic chuck can be damped prior to clamping.
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公开(公告)号：US20220029567A1
公开(公告)日：2022-01-27
申请号：US17331712
申请日：2021-05-27
发明人： David L. Trumper , Benjamin Weinreb
摘要： A motor system can include a bearingless stator having a plurality of magnetic windings including rotation windings and suspension windings; a dipole interior permanent magnet (IPM) rotor positioned within the stator, the rotor having a plurality of permanent magnets disposed within a cylindrical structure; one or more position sensors to measure radial and angular position of the rotor; and a controller configured to receive measurements from the one or more position sensors and to generate current commands for the stator to excite the rotation windings to generate torque and to excite the suspension windings to stabilize the rotor within the stator.
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公开(公告)号：US20190330584A1
公开(公告)日：2019-10-31
申请号：US16358137
申请日：2019-03-19
摘要： Organ-on-chip platforms with reduced fluid volumes include circulating fluid volumes of below 1000 μL, preferably about 500 μL or less. The platforms are adjustable for culturing cells with varied oxygen demand at various seeding densities. The platforms include at least one lane, wherein each lane includes at least one cell culture well, at least one oxygenator for fluid oxygenation, and a pump system containing at least one pump per lane. The oxygenator may include a separate fluid path for oxygenating the fluid, which allows controlling and measuring the oxygen concentration in the fluid, shortening the diffusion length, and passively diffusing oxygen. Provided are also different configurations for the oxygenator, fluid circulation in the platforms, attachment means for securing scaffolds to culture wells, and pneumatic plates.
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