Tethered Conformation Capture
    3.
    发明申请
    Tethered Conformation Capture 审中-公开
    束缚构象捕获

    公开(公告)号:US20110287947A1

    公开(公告)日:2011-11-24

    申请号:US12782616

    申请日:2010-05-18

    申请人: Lin Chen Reza Kalhor

    发明人: Lin Chen Reza Kalhor

    IPC分类号: C40B30/00 C12Q1/68

    摘要: Disclosed are methods and systems for determining the three-dimensional structure of chromatin in eukaryotic cells. More specifically, disclosed are methods and systems for obtaining chromatin structural information by surface immobilization, i.e tethering crosslinked protein:DNA complexes and/or ligated DNA complexes to media such as beads, gels, and or matrices during the conformation capture assay. In general, the method includes contacting a cell with a cross-linking reagent to cross-link DNA and protein in the cell; lysing the cell, producing cross-linked protein:DNA complexes by cutting the chromatin using a chemical, physical or enzymatic method, substantially immobilizing the cross-linked protein:DNA complexes, ligating the cross-linked protein:DNA complexes intramolecularly such that the ligated protein:DNA complexes represent structural organization of the chromatin; characterizing the ligated DNA by sequencing or other methods; and identifying any structural organization of the chromatin. The structural organization preferably includes information relating to interacting loci of the chromatin.

    摘要翻译: 公开了用于确定真核细胞中染色质的三维结构的方法和系统。 更具体地,公开了用于通过表面固定获得染色质结构信息的方法和系统,即在构象捕获测定期间将交联的蛋白质:DNA复合物和/或连接的DNA复合物与培养基如珠,凝胶和/或基质连接。 通常,该方法包括使细胞与交联剂接触以在细胞中交联DNA和蛋白质; 裂解细胞,通过使用化学,物理或酶学方法切割染色质来产生交联蛋白质:DNA复合物,基本上固定交联的蛋白质:DNA复合物,分子内连接交联的蛋白质:DNA复合物,使得连接的 蛋白质:DNA复合物代表染色质的结构组织; 通过测序或其他方法表征连接的DNA; 并识别染色质的任何结构组织。 结构组织优选地包括与染色质的相互作用位点有关的信息。

    Pet hair brush
    4.
    外观设计

    公开(公告)号:USD923259S1

    公开(公告)日:2021-06-22

    申请号:US29768357

    申请日:2021-01-28

    申请人: Lin Chen

    设计人: Lin Chen

    System and method for generating information file based on parallel processing
    5.
    发明授权
    System and method for generating information file based on parallel processing 有权
    基于并行处理生成信息文件的系统和方法

    公开(公告)号:US09531792B2

    公开(公告)日:2016-12-27

    申请号:US14007963

    申请日:2012-03-30

    申请人: Lin Chen Yuming Mao

    发明人: Lin Chen Yuming Mao

    IPC分类号: H04L29/08 G06F17/30

    CPC分类号: H04L67/10 G06F17/30067

    摘要: The present invention proposes a information file generating system and method based on parallel processing. Wherein, said information file generating system based on parallel processing comprises a file request processing device, a control device, a temporary task processing device, an abnormity processing device and an input/output device. Among them, said file request processing device is used to receive and analyze a file request instruction from an application server, and create an information file generation task and at least one temporary information file generation task according to the result of the analysis. The information file generating system and method based on parallel processing disclosed in the present invention are easy to be operated, can ensure the real-time performance and accuracy, and can improve the work efficiency and performance of the system.

    摘要翻译: 本发明提出一种基于并行处理的信息文件生成系统和方法。 其中,所述基于并行处理的信息文件生成系统包括文件请求处理装置,控制装置,临时任务处理装置,异常处理装置以及输入输出装置。 其中,所述文件请求处理装置用于从应用服务器接收和分析文件请求指令,并根据分析结果创建信息文件生成任务和至少一个临时信息文件生成任务。 本发明公开的基于并行处理的信息文件生成系统和方法易于操作,可以保证实时的性能和准确性,并能提高系统的工作效率和性能。

    Memory channel selection in a multi-channel memory
    6.
    发明授权
    Memory channel selection in a multi-channel memory 有权
    多通道存储器中的存储器通道选择

    公开(公告)号:US09009441B2

    公开(公告)日:2015-04-14

    申请号:US13487813

    申请日:2012-06-04

    申请人: Lin Chen Long Chen

    发明人: Lin Chen Long Chen

    IPC分类号: G06F12/06 G06F9/35

    摘要: In general, this disclosure describes techniques for selecting a memory channel in a multi-channel memory system for storing data, so that usage of the memory channels is well-balanced. A request to write data to a logical memory address of a memory system may be received. The logical memory address may include a logical page number and a page offset, where the logical page number maps to a physical page number and the logical memory address maps to a physical memory address. A memory unit out of a plurality of memory units in the memory system may be determined by performing a logical operation on one or more bits of the page offset and one or more bits of the physical page number. The data may be written to a physical memory address in the determined memory unit in the memory system.

    摘要翻译: 通常,本公开描述了用于在用于存储数据的多通道存储器系统中选择存储器通道的技术,使得存储器通道的使用是良好平衡的。 可以接收将数据写入存储器系统的逻辑存储器地址的请求。 逻辑存储器地址可以包括逻辑页码和页偏移,其中逻辑页码映射到物理页号,并且逻辑存储器地址映射到物理存储器地址。 存储器系统中的多个存储器单元中的存储单元可以通过对页面偏移的一个或多个位和物理页码的一个或多个位执行逻辑运算来确定。 数据可以写入存储器系统中确定的存储器单元中的物理存储器地址。

    Wireless communication system
    7.
    发明授权

    公开(公告)号:US08780886B2

    公开(公告)日:2014-07-15

    申请号:US13571534

    申请日:2012-08-10

    IPC分类号: H04J3/06

    摘要: A wireless communication system base station, and a remote radio head (RRH) and a computer-implemented synchronization method for the wireless communication system base station. The RRH is communicably coupled to a baseband unit (BBU) of the wireless communication system base station through a network, and the BBU processes and transmits downlink data to the RRH. The RRH includes: a time-delay measurement unit for measuring a time-delay for the downlink data to arrive at the RRH from the BBU; and a time-delay notification unit for notifying from the RRH to the BBU of time-delay data on the time-delay measured by the time-delay measurement unit, wherein the time-delay data is used to advance the starting time for the BBU to process and transmit the downlink data by an amount of time obtained based on the time-delay data.

    Wireless communication system
    8.
    发明授权
    Wireless communication system 有权
    无线通信系统

    公开(公告)号:US08767710B2

    公开(公告)日:2014-07-01

    申请号:US13392887

    申请日:2010-08-17

    IPC分类号: H04J3/06

    摘要: A wireless communication system base station, and a remote radio head (RRH) and a computer-implemented synchronization method for the wireless communication system base station. The RRH is communicably coupled to a baseband unit (BBU) of the wireless communication system base station through a network, and the BBU processes and transmits downlink data to the RRH. The RRH includes: a time-delay measurement unit for measuring a time-delay for the downlink data to arrive at the RRH from the BBU; and a time-delay notification unit for notifying from the RRH to the BBU of time-delay data on the time-delay measured by the time-delay measurement unit, wherein the time-delay data is used to advance the starting time for the BBU to process and transmit the downlink data by an amount of time obtained based on the time-delay data.

    摘要翻译: 无线通信系统基站,以及用于无线通信系统基站的远程无线电头(RRH)和计算机实现的同步方法。 RRH通过网络可通信地耦合到无线通信系统基站的基带单元(BBU),并且BBU处理并向RRH发送下行链路数据。 RRH包括:时间延迟测量单元,用于测量从BBU到达RRH的下行链路数据的时间延迟; 以及时间延迟通知单元,用于从RRH向BBU通知由延时测量单元测量的时间延迟数据,其中时延数据用于提前BBU的开始时间 根据时间延迟数据获得的时间量来处理和发送下行数据。

    Error detection in high-speed asymmetric interfaces
    9.
    发明授权
    Error detection in high-speed asymmetric interfaces 有权
    高速非对称接口中的错误检测

    公开(公告)号:US08661300B1

    公开(公告)日:2014-02-25

    申请号:US13169977

    申请日:2011-06-27

    IPC分类号: G06F11/00

    CPC分类号: G06F11/10

    摘要: A system and method for detecting errors in high-speed asymmetric interfaces are described. Embodiments include transmitting digital data between a first system component and a second system component over a bidirectional interface, wherein the first component is significantly more intelligent than the second component. The first component controls many operations of the second component, including receiving a signature from the second component over an existing line of the interface. The signature received is compared to a signature stored by the first component. Both signatures correspond to a transaction over the interface. Based on the comparison, the first component determines whether the transaction was successful, and directs the second component as necessary.

    摘要翻译: 描述了用于检测高速非对称接口中的错误的系统和方法。 实施例包括通过双向接口在第一系统组件和第二系统组件之间传输数字数据,其中第一组件比第二组件明显更智能。 第一个组件控制第二个组件的许多操作,包括通过接口的现有行接收来自第二个组件的签名。 所接收的签名与由第一组件存储的签名进行比较。 两个签名对应于接口上的事务。 基于比较,第一个组件确定事务是否成功,并根据需要引导第二个组件。