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公开(公告)号：US20140073738A1
公开(公告)日：2014-03-13
申请号：US14082336
申请日：2013-11-18
Applicant: LIFE TECHNOLOGIES AS , LIFE TECHNOLOGIES CORPORATION
Inventor： Geir FONNUM , Grete I. MODAHL , Nini H. KJUS , Astrid E. MOLTEBERG , Diem TRAN , Jo AASERUD , Talha M. GOKMEN , Steven M. MENCHEN , Carl FULLER , Luisa ANDRUZZI , Wolfgang HINZ
IPC: C08F130/08 , C08F8/32
CPC classification number: C08F130/08 , C07F7/1804 , C07F7/188 , C08F2/20 , C08F2/26 , C08F6/24 , C08F8/12 , C08F8/32 , C08F8/34 , C08F220/58 , C08F222/385 , C08F230/08 , C08F2800/20 , C08J9/20 , C08J2343/04 , C12P19/34 , C12Q1/686 , C12Q1/6874 , G01N27/4145 , Y10T428/2982 , C08F257/02 , C08F2222/1013 , C08F212/36 , C08F220/60 , C12Q2563/149 , C12Q2563/159 , C12Q2565/543
Abstract: A method of forming a particle includes, in a disperse phase within an aqueous suspension, polymerizing a plurality of mer units of a hydrophilic monomer having a hydrophobic protection group, thereby forming a polymeric particle including a plurality of the hydrophobic protection groups. The method further includes converting the polymeric particle to a hydrophilic particle.
Abstract translation: 形成颗粒的方法包括在水性悬浮液中的分散相中聚合具有疏水保护基团的亲水性单体的多个聚合单元，从而形成包含多个疏水保护基团的聚合物颗粒。 该方法还包括将聚合物颗粒转化为亲水性颗粒。
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公开(公告)号：US20180223359A1
公开(公告)日：2018-08-09
申请号：US15945348
申请日：2018-04-04
Applicant: Life Technologies Corporation
Inventor： Steven M. MENCHEN , Alan BLANCHARD , Luisa ANDRUZZI , Shaheer H. KHAN , Dmitriy GREMYACHINSKIY , Alfred LUI , Craig STOLARCZYK , Tanya SOKOLSKY , Prasanna Krishnan THWAR
IPC: C12Q1/6876 , C08F8/40 , C12Q1/6834
Abstract: A method of conjugating a substrate includes exchanging a counter ion associated with a biomolecule with a lipophilic counter ion to form a biomolecule complex, dispersing the biomolecule complex in a nonaqueous solvent, and coupling the biomolecule complex to a substrate in the presence of the nonaqueous solvent.
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公开(公告)号：US20170007977A1
公开(公告)日：2017-01-12
申请号：US15203582
申请日：2016-07-06
Applicant: LIFE TECHNOLOGIES CORPORATION
Inventor： Alexander MASTROIANNI , Scott C. BENSON , Steven M. MENCHEN , John SCOTT
IPC: B01J19/00
CPC classification number: B01J19/0046 , B01J2219/00317 , B01J2219/005 , B01J2219/00545 , B01J2219/00648 , B01J2219/00659 , B01J2219/00677 , B01J2219/00722 , C12Q1/6806 , C12Q1/6837 , C12Q1/6869 , C12Q2535/122 , C12Q2563/155 , C12Q2565/607 , C12Q2565/629
Abstract: A method of preparing a discrete polymer network array include mixing a plurality of nucleic acid polymer networks with a plurality of color-activated polymer networks to form a dispersion, applying the dispersion to an array of wells, the nucleic acid polymer networks selectively depositing into wells of the array of wells, and rinsing the array of wells to selectively remove the plurality of color-activated polymer networks.
Abstract translation: 制备离散聚合物网络阵列的方法包括将多个核酸聚合物网络与多个着色活化聚合物网络混合以形成分散体，将该分散体施加到孔阵列上，将核酸聚合物网络选择性地沉积到孔中 的孔阵列，并且冲洗孔阵列以选择性地去除多个着色活化聚合物网络。
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公开(公告)号：US20170002152A1
公开(公告)日：2017-01-05
申请号：US15200533
申请日：2016-07-01
Applicant: LIFE TECHNOLOGIES CORPORATION , LIFE TECHNOLOGIES AS
Inventor： Geir FONNUM , Steven M. MENCHEN , Talha M. GOKMEN , Pontus LUNDBERG , Prasanna Krishnan THWAR , Alfred LUI , Lily LU , Wolfgang HINZ , Lene HUSABOE , Elisabeth BREIVOLD , Astrid Evenroed MOLTEBERG , Synne LARSEN
IPC: C08J3/075 , C08F220/70
CPC classification number: C08J3/075 , C08F8/12 , C08F220/58 , C08F220/70 , C08F2230/085 , C08J2333/26 , C08F222/38
Abstract: A polymer substrate, such as a polymer particle, is formed from a carboxyl functional monomer. In an example, the carboxyl functional monomer has a protection group in place of the OH of the carboxyl group. Once the monomer is polymerized, such a protection group can be removed, providing a polymer network with carboxyl functional sites. Such sites can be used to attach other functionality to the polymer substrate.
Abstract translation: 聚合物基材如聚合物颗粒由羧基官能单体形成。 在一个实例中，羧基官能单体具有保护基代替羧基的OH。 一旦单体聚合，就可以除去这种保护基团，从而提供具有羧基官能位点的聚合物网络。 这种位点可用于将其它功能性附加到聚合物基材上。
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公开(公告)号：US20160137762A1
公开(公告)日：2016-05-19
申请号：US15005420
申请日：2016-01-25
Applicant: LIFE TECHNOLOGIES CORPORATION , LIFE TECHNOLOGIES AS
Inventor： Geir FONNUM , Grete Irene MODAHL , Nini Hofsloekken KJUS , Astrid Evenroed MOLTEBERG , Diem Thuy Thi TRAN , Jo AASERUD , M. Talha GOKMEN , Steven M. MENCHEN , Carl FULLER , Luisa ANDRUZZI , Wolfgang HINZ
IPC: C08F130/08 , C08F6/24 , C08J9/20
CPC classification number: C08F130/08 , C07F7/1804 , C07F7/188 , C08F2/20 , C08F2/26 , C08F6/24 , C08F8/12 , C08F8/32 , C08F8/34 , C08F220/58 , C08F222/385 , C08F230/08 , C08F2800/20 , C08J9/20 , C08J2343/04 , C12P19/34 , C12Q1/686 , C12Q1/6874 , G01N27/4145 , Y10T428/2982 , C08F257/02 , C08F2222/1013 , C08F212/36 , C08F220/60 , C12Q2563/149 , C12Q2563/159 , C12Q2565/543
Abstract: A method of forming a particle includes, in a disperse phase within an aqueous suspension, polymerizing a plurality of mer units of a hydrophilic monomer having a hydrophobic protection group, thereby forming a polymeric particle including a plurality of the hydrophobic protection groups. The method further includes converting the polymeric particle to a hydrophilic particle.
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Patent Agency Ranking
公开(公告)号：US20160097095A1
公开(公告)日：2016-04-07
申请号：US14970241
申请日：2015-12-15
Applicant: LIFE TECHNOLOGIES CORPORATION , LIFE TECHNOLOGIES AS
Inventor： Geir FONNUM , Grete Irene MODAHL , Nini Hofslokken KJUS , Astrid Evenroed MOLTEBERG , Diem TRAN , Jo AASERUD , Talha M. GOKMEN , Steven M. MENCHEN , Carl FULLER , Luisa ANDRUZZI , Wolfgang HINZ
IPC: C12Q1/68 , G01N27/414
CPC classification number: C08F130/08 , C07F7/1804 , C07F7/188 , C08F2/20 , C08F2/26 , C08F6/24 , C08F8/12 , C08F8/32 , C08F8/34 , C08F220/58 , C08F222/385 , C08F230/08 , C08F2800/20 , C08J9/20 , C08J2343/04 , C12P19/34 , C12Q1/686 , C12Q1/6874 , G01N27/4145 , Y10T428/2982 , C08F257/02 , C08F2222/1013 , C08F212/36 , C08F220/60 , C12Q2563/149 , C12Q2563/159 , C12Q2565/543
Abstract: A method of forming a particle includes, in a disperse phase within an aqueous suspension, polymerizing a plurality of mer units of a hydrophilic monomer having a hydrophobic protection group, thereby forming a polymeric particle including a plurality of the hydrophobic protection groups. The method further includes converting the polymeric particle to a hydrophilic particle.
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公开(公告)号：US20230167210A1
公开(公告)日：2023-06-01
申请号：US18101785
申请日：2023-01-26
Applicant: LIFE TECHNOLOGIES CORPORATION , LIFE TECHNOLOGIES AS
Inventor： Geir FONNUM , Grete Irene MODAHL , Nini Hofsloekken KJUS , Astrid Evenroed MOLTEBERG , Diem Thuy Thi TRAN , Jo AASERUD , M. Talha GOKMEN , Steven M. MENCHEN , Carl FULLER , Luisa ANDRUZZI , Wolfgang HINZ
IPC: C08F130/08 , C07F7/18 , C08F8/12 , C12Q1/686 , C08F2/20 , C08F2/26 , C08F230/08 , C08F6/24 , C08F222/38 , C08F8/32 , C08F8/34 , C12P19/34 , C12Q1/6874 , G01N27/414 , C08J9/20
CPC classification number: C08F130/08 , C07F7/1804 , C08F8/12 , C12Q1/686 , C07F7/188 , C08F2/20 , C08F2/26 , C08F230/085 , C08F6/24 , C08F222/385 , C08F8/32 , C08F8/34 , C12P19/34 , C12Q1/6874 , G01N27/4145 , C08J9/20 , Y10T428/2982 , C08F2800/20 , C08F220/603
Abstract: A method of forming a particle includes, in a disperse phase within an aqueous suspension, polymerizing a plurality of mer units of a hydrophilic monomer having a hydrophobic protection group, thereby forming a polymeric particle including a plurality of the hydrophobic protection groups. The method further includes converting the polymeric particle to a hydrophilic particle.
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公开(公告)号：US20180237595A1
公开(公告)日：2018-08-23
申请号：US15871863
申请日：2018-01-15
Applicant: Life Technologies AS , Life Technologies Corporation
Inventor： Geir FONNUM , Steven M. MENCHEN , M. Talha GOKMEN , Pontus LUNDBERG , Prasanna Krishnan THWAR , Alfred LUI , Lily LU , Wolfgang HINZ , Lene Husaboe , Elisabeth BREIVOLD , Astrid Evenroed MOLTEBERG , Synne LARSEN
CPC classification number: C08J3/075 , C08F8/12 , C08F220/58 , C08F220/70 , C08F2230/085 , C08J2333/26 , C08F222/38
Abstract: A polymer substrate, such as a polymer particle, is formed from a carboxyl functional monomer. In an example, the carboxyl functional monomer has a protection group in place of the OH of the carboxyl group. Once the monomer is polymerized, such a protection group can be removed, providing a polymer network with carboxyl functional sites. Such sites can be used to attach other functionality to the polymer substrate.
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公开(公告)号：US20160097094A1
公开(公告)日：2016-04-07
申请号：US14970192
申请日：2015-12-15
Applicant: LIFE TECHNOLOGIES CORPORATION , LIFE TECHNOLOGIES AS
Inventor： Geir FONNUM , Grete Irene MODAHL , Nini Hofslokken KJUS , Astrid Evenroed MOLTEBERG , Diem TRAN , Jo AASERUD , Talha M. GOKMEN , Steven M. MENCHEN , Carl FULLER , Luisa ANDRUZZI , Wolfgang HINZ
CPC classification number: C08F130/08 , C07F7/1804 , C07F7/188 , C08F2/20 , C08F2/26 , C08F6/24 , C08F8/12 , C08F8/32 , C08F8/34 , C08F220/58 , C08F222/385 , C08F230/08 , C08F2800/20 , C08J9/20 , C08J2343/04 , C12P19/34 , C12Q1/686 , C12Q1/6874 , G01N27/4145 , Y10T428/2982 , C08F257/02 , C08F2222/1013 , C08F212/36 , C08F220/60 , C12Q2563/149 , C12Q2563/159 , C12Q2565/543
Abstract: A method of forming a particle includes, in a disperse phase within an aqueous suspension, polymerizing a plurality of mer units of a hydrophilic monomer having a hydrophobic protection group, thereby forming a polymeric particle including a plurality of the hydrophobic protection groups. The method further includes converting the polymeric particle to a hydrophilic particle.
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公开(公告)号：US20140080966A1
公开(公告)日：2014-03-20
申请号：US14081263
申请日：2013-11-15
Applicant: LIFE TECHNOLOGIES AS , LIFE TECHNOLOGIES CORPORATION
Inventor： Nini H. KJUS , Geir FONNUM , Bruce BRANCHAUD , Lai-Qiang Ying , Steven M. MENCHEN , Dmitriy GREMYACHINSKIY , Hee Chol KANG
IPC: C07F7/10 , C08K3/20 , C08F236/20
CPC classification number: C08F230/08 , C07F7/10 , C07F7/1804 , C08F220/58 , C08F222/385 , C08F236/20 , C08K3/20
Abstract: A silyl protected diacrylamide compound is described. A method of forming such a compound includes mixing a silylation reagent with a hydroxylated diamine compound under first reactive conditions to form a product in a first solution, separating the product from the first solution, and mixing the product with acryloyl chloride under second reactive conditions in a second solution to form a silyl protected diacrylamide compound.
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