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公开(公告)号：US12228719B2
公开(公告)日：2025-02-18
申请号：US17636034
申请日：2019-08-27
Applicant: LEICA MICROSYSTEMS CMS GMBH
Inventor： Christian Schumann , Christian Schulz , Arnold Mueller-Rentz , Andreas Lotter
Abstract: An optical imaging device for a microscope includes an objective and an optical system configured to interact with the objective for optically imaging an object selectively in a first operating mode and a second operating mode. The optical system includes a first optical subsystem associated with the first operating mode, and a second optical subsystem associated with the second operating mode. The first optical subsystem is configured to form a first image of the object with a first magnification. The second optical subsystem is configured to form a second image of the object with a second magnification that is less than the first magnification. The second optical subsystem includes an optical module insertable into the optical path for selecting the second operating mode. The optical module includes a lens element with a positive refractive power.
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公开(公告)号：US12038570B2
公开(公告)日：2024-07-16
申请号：US17369972
申请日：2021-07-08
Applicant: Leica Microsystems CMS GmbH
Inventor： Christian Schumann , Christian Schulz , Alexander Weiss
CPC classification number: G02B21/33 , G02B21/0048 , G02B21/006
Abstract: A microscope includes: an optical system including an immersion objective for an immersion medium of a predetermined refractive index; an aperture stop; and a processor for setting an immersion-free imaging mode in which the optical system is operated without immersion medium. The processor controls the aperture stop in the immersion-free imaging mode to set a numerical aperture of the immersion objective to a reduced value which is lower than a nominal value of the numerical aperture, the numerical aperture being equal to the nominal value when the optical system is operated using the immersion medium without reducing the numerical aperture by the aperture stop. The processor controls the optical system in accordance with the reduced value of the numerical aperture in the immersion-free imaging mode to generate at least one image representing the overview image of the sample.
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公开(公告)号：US11933972B2
公开(公告)日：2024-03-19
申请号：US17423924
申请日：2019-12-19
Applicant: LEICA MICROSYSTEMS CMS GMBH
Inventor： Andreas Lotter , Christian Schulz , Christian Schumann
CPC classification number: G02B27/0025 , G02B15/143 , G02B15/20 , G02B21/025 , G02B21/36
Abstract: An optical system for a microscope for imaging an object includes: a telescope system having an optical correction unit, which is adjustable in order to correct a spherical imaging aberration, and having a zoom optical unit, which is adjustable in order to adapt a magnification of the telescope system to a ratio of two refractive indices, one of which is assigned to an object side and an other of which is assigned to an image side, within a predetermined magnification range. The telescope system is telecentric over an entire magnification range both with respect to the object side and with respect to the image side by the zoom optical unit contained in the telescope system.
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公开(公告)号：US10133063B2
公开(公告)日：2018-11-20
申请号：US15327659
申请日：2015-07-21
Applicant: Leica Microsystems CMS GmbH
Inventor： Christian Schulz , Christian Schumann , Cornell Gonschior , Tobias Bauer
Abstract: A microscope includes at least one correction unit arranged in a beam path for correcting a variable spherical aberration. The correction unit has at least one optical correction element that is arranged in a convergent or divergent area of the beam path such that the optical correction element is movable along an optical axis. The at least one optical correction element has at least one correction surface. A part of the at least one correction surface through which the convergent or divergent area of the beam path passes forms a correction-effective surface section whose radial extension crosswise to the optical axis is adjustable by moving the correction element along the optical axis.
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公开(公告)号：US20210165198A1
公开(公告)日：2021-06-03
申请号：US16768900
申请日：2018-11-27
Applicant: Leica Microsystems CMS GmbH
Inventor： Arnold Mueller-Rentz , Christian Schulz
Abstract: A microscope system includes a detection unit having a color beam splitter arrangement with three beam splitter prisms, each having first, second and third prism surfaces. The first prism surfaces face in the same direction and are oriented parallel to one another at a right angle to an optical axis. The first and second prism surfaces are oriented in each case at acute angles to one another. The second and third prism surfaces are oriented in each case at right or obtuse angles to one another. The third and first prism surfaces are oriented in each case at acute angles to one another. A prismatic compensation element having first and second prism surfaces is assigned to each prism. The second prism surface of each of the compensation elements is arranged in a common plane with or parallel to the second prism surface of the respectively assigned prism.
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Patent Agency Ranking
公开(公告)号：US10732395B2
公开(公告)日：2020-08-04
申请号：US15956788
申请日：2018-04-19
Applicant: Leica Microsystems CMS GmbH
Inventor： Christian Schulz , Christian Schumann
Abstract: An immersion objective lens for a microscope includes a first lens group having positive refractive power, a second lens group having positive refractive power, a third lens group having negative refractive power and a fourth lens group having positive refractive power disposed in this sequence from the object side. The second lens group is moveable along an optical axis so as to achieve a corrective effect with respect to a spherical aberration, such that a sum of a distance between the second lens group and the first lens group and of a distance between the second lens group and the third lens group is constant. The corrective effect of the second lens group is predetermined such that the spherical aberration is minimized for a light incidence that corresponds to a mean numerical aperture that lies between zero and a nominal aperture of the immersion objective lens.
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公开(公告)号：US09772482B2
公开(公告)日：2017-09-26
申请号：US14437508
申请日：2013-10-22
Applicant: LEICA MICROSYSTEMS CMS GMBH
Inventor： Christian Schumann , Ralf Krueger , Tobias Bauer , Arnold Mueller-Rentz , Klaus Hermanns , Christian Schulz
IPC: G02B21/06 , G02B21/08 , G02B21/18 , F21V33/00 , G01N21/31 , F21Y103/00 , F21Y105/00 , F21Y115/20 , F21Y115/15
CPC classification number: G02B21/06 , F21V33/0068 , F21Y2103/00 , F21Y2105/00 , F21Y2115/15 , F21Y2115/20 , G01N21/31 , G01N2201/061 , G01N2201/0628 , G02B21/088 , G02B21/18
Abstract: An illumination device for an optical device, a microscope or a macroscope includes a first illumination source configured to emit light which is directed via an illumination beam path onto an object to be illuminated that is arranged in an object plane. At least one second illumination source is positionable in the illumination beam path, and is transparent or semitransparent as well as self-luminous. The at least one second illumination source is configured to allow light emitted from the first illumination source to pass through at least in part. The object plane having the object to be illuminated is configured to be illuminated both by the first and by the at least one second illumination source.
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公开(公告)号：US09488818B2
公开(公告)日：2016-11-08
申请号：US14191557
申请日：2014-02-27
Applicant: Leica Microsystems CMS GmbH
Inventor： Tobias Bauer , Christian Schulz
Abstract: A microscope immersion objective having a numerical aperture of NA>1.36 includes a front lens group. The front lens group has a first, object-side optical element having a plane parallel plate and a second optical element having a hyper-hemisphere. The plane parallel plate is wrung together with a planar side of the hyper-hemisphere.
Abstract translation: 具有数值孔径NA> 1.36的显微镜浸没物镜包括前透镜组。 前透镜组具有具有平面平行板的第一物体侧光学元件和具有超半球的第二光学元件。 平面平行板与超半球的平面侧一起拧紧。
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公开(公告)号：US20240094518A1
公开(公告)日：2024-03-21
申请号：US17947257
申请日：2022-09-19
Applicant: Leica Microsystems CMS GmbH
Inventor： Benjamin Deissler , Christian Schulz , Christian Schumann
CPC classification number: G02B21/16 , G01N21/6458 , G02B21/08
Abstract: A microscope for fluorescence light imaging includes an illumination device configured to direct excitation light along an excitation beam path into a sample, and a detection device configured to detect fluorescence light emanating from the sample along a detection beam path which is located in a same hemisphere relative to the sample as the excitation beam path, wherein the illumination device includes a light guiding system configured to guide the excitation light such that, in phase space defined by position and angle of a light beam, a support of the excitation beam path is disjunct from a support of the detection beam path, and wherein the detection device includes at least one emission filter configured to allow the fluorescence light propagating along the detection beam path to be detected for fluorescence light imaging while discarding light that is spectrally different from the fluorescence light.
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公开(公告)号：US11262567B2
公开(公告)日：2022-03-01
申请号：US16605775
申请日：2018-04-20
Applicant: Leica Microsystems CMS GmbH
Inventor： Christian Schulz
Abstract: The invention relates to a correction objective (10), comprising a first lens group (12) of positive optical power, a second lens group (14) of positive optical power, a third lens group (16) of negative optical power, and a fourth lens group (18) of positive optical power, which are arranged in this order from the object side, the second lens group (14) being movable along the optical axis (O) in such a way that the sum of the distance (V1) between the second lens group (14) and the first lens group (12) and the distance (V2) between the second lens group (14) and the third lens group (16) is constant. The image scale of the second lens group (14) lies in a range of −0.9 to −1.1.
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