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18 条记录 (耗时 0.04 秒)

    Preparation of 1,2-propanediol
    6.
    发明授权
    Preparation of 1,2-propanediol 失效
    1,2-丙二醇的制备

    公开(公告)号：US5616817A

    公开(公告)日：1997-04-01

    申请号：US559625

    申请日：1995-11-20

    申请人： Ludwig Schuster ,  Manfred Eggersdorfer

    发明人： Ludwig Schuster ,  Manfred Eggersdorfer

    IPC分类号： B01J27/199 ,  C07B61/00 ,  C07C29/132 ,  C07C29/60 ,  C07C31/20

    CPC分类号： C07C29/60 ,  Y02P20/52

    摘要： A process for the preparation of 1,2-propanediol by catalytic hydrogenation of glycerol at elevated temperature and elevated pressure, which comprises using glycerol having a water content of up to 20% by weight and a catalyst comprising the metals cobalt, copper, manganese and molybdenum in amounts of, based on the total weight of the catalyst,from 40 to 70% by weight of cobalt,from 10 to 20% by weight of copper,from 0 to 10% by weight of manganese andfrom 0 to 10% by weight of molybdenum,where this catalytically active material may additionally contain inorganic polyacids and/or heteropolyacids in an amount of up to 10% by weight, based on the total weight of the catalyst.

    摘要翻译： 一种通过在升高的温度和升高的压力下对甘油进行催化氢化制备1,2-丙二醇的方法，其包括使用含水量高达20重量％的甘油和包含金属钴，铜，锰的催化剂和 钼，以催化剂的总重量为40-70重量％的钴，10-20重量％的铜，0-10重量％的锰和0-10重量％ 钼的重量，其中该催化活性材料可以另外包含基于催化剂总重量高达10重量％的无机多酸和/或杂多酸。

    Purification of salts of riboflavin 5'-phosphate, in particular of monosodium riboflavin 5'-phosphate
    7.
    发明授权
    Purification of salts of riboflavin 5'-phosphate, in particular of monosodium riboflavin 5'-phosphate 失效
    核黄素5'-磷酸盐，特别是核黄素5'-磷酸一钠的盐的纯化

    公开(公告)号：US4987229A

    公开(公告)日：1991-01-22

    申请号：US323795

    申请日：1989-03-15

    申请人： Walter Dobler ,  Manfred Eggersdorfer ,  Joachim Paust

    发明人： Walter Dobler ,  Manfred Eggersdorfer ,  Joachim Paust

    IPC分类号： C07D475/14 ,  C07F9/6561

    CPC分类号： C07F9/65618

    摘要： Salts of riboflavin 5'-phosphate which are obtained by phosphorylation of riboflavin and reaction of the resulting riboflavin 5'-phosphate (5'-FMN), contaminated with unconverted riboflavin and isomeric riboflavin monophosphates and diphosphates, with an alkali metal hydroxide or a nitrogen base are purified by a process in which(a) a roughly 1-15% strength by weight homogeneous, clear, aqueous 5'-FMN salt solution having a pH of from 4 to 7 is prepared from the crude 5'-FMN obtained in the phosphorylation, water and the alkali metal hydroxide or the nitrogen base, preferably sodium hydroxide solution, if necessary with heating at from 30.degree. to 100.degree. C.,(b) the resulting solution is treated with a suitable polymeric adsorber resin and(c) the 5'-FMN salt substantially freed from unconverted riboflavin is isolated from the resulting solution and, if desired, the solution is fed to a subsequent fine purification.Treatment with the suitable polymeric adsorber resin is advantageously carried out in a column filled with adsorber resin. The subsequent fine purification can be effected by evaporative crystallization or by chromatographing a 5'-FMN solution, containing from 1 to 15% by weight of dry substance, in water or in a mixture of water and a lower aliphatic alcohol, having a pH of from 4 to 7, in a minimum amount of from 5 to 50% of the bed volume of the column over RP silica gel derivatized with alkyl groups, using water, or a mixture of water and a lower aliphatic alcohol, as the eluant. Preparative chromatography of 5'-FMN salts over derivatized RP silica gel using water, or a mixture of water and a lower aliphatic alcohol, as the solvent and eluant is also claimed independently of pretreatment with the suitable adsorber resin.

    摘要翻译： 通过核黄素磷酸化获得的核黄素5'-磷酸盐的盐和由未转化的核黄素和异构核黄素单磷酸酯和二磷酸酯污染的所得核黄素5'-磷酸（5'-FMN）与碱金属氢氧化物或氮 碱通过以下方法纯化，其中（a）从所得粗制5'-FMN制备了具有约1-15％重量的均匀，透明的pH5-4的5-FMN盐水溶液， 磷酸化，水和碱金属氢氧化物或氮碱，优选氢氧化钠溶液，如果需要，在30℃至100℃下加热，（b）所得溶液用合适的聚合物吸附树脂处理，（c ）从所得溶液中分离出基本上未转化的核黄素的5'-FMN盐，并且如果需要，将溶液加入到随后的精细纯化中。 用合适的聚合物吸附树脂处理有利地在填充有吸附树脂的柱中进行。 随后的精细纯化可以通过蒸发结晶或通过色谱法将含有1至15重量％干物质的5-FMN溶液在水或水和低级脂族醇的混合物中进行，其pH为 作为洗脱剂，使用水或水和低级脂族醇的混合物，用烷基衍生的RP硅胶的柱体积的最小量为5至50％。 独立于合适的吸附剂树脂的预处理，也要求使用水，或水和低级脂族醇的混合物作为溶剂和洗脱剂的衍生化RP硅胶的5-FMN盐的制备色谱法。