Polyurethane-polyurea coatings
    2.
    发明申请
    Polyurethane-polyurea coatings 审中-公开
    聚氨酯 - 聚脲涂料

    公开(公告)号:US20070166552A1

    公开(公告)日:2007-07-19

    申请号:US11651637

    申请日:2007-01-10

    IPC分类号: B32B27/40 C08L75/00 C08G18/00

    摘要: The present invention provides coating agents made up of the reaction product of a) a polycarbonatediol component comprising a1) a polytetramethylene glycol-based polycarbonatediol with a molecular weight of between 400 and 8000, and a2) optionally other polyols with a molecular weight of from 200 to 8000, b) 0.5-2.0 mol per mol of a) of a chain extender selected from the group consisting of a low-molecular weight aliphatic or cycloaliphatic diol, a low-molecular weight aliphatic or cycloaliphatic diamine, and hydrazine, and c) 1.5-3.0 mol per mol of a) of an aliphatic, cycloaliphatic or aromatic diisocyanate, dissolved in d) 40-90 percent by weight (based on the total formulation) of an organic solvent selected from the group consisting of linear or cyclic esters, ketones, alcohols, aromatic compounds and mixtures thereof.

    摘要翻译: 本发明提供由a)聚碳酸酯二醇组分的反应产物组成的包衣剂,其包含a1)分子量为400-8000的聚四亚甲基二醇基聚碳酸二醇,和a2)任选的其它分子量为200的多元醇 至8000,b)每摩尔a)0.5-2.0摩尔a)选自低分子量脂族或脂环族二醇,低分子量脂族或脂环族二胺和肼的扩链剂,以及c) 溶于d)40-90重量%(基于总配方)的选自线性或环状酯的有机溶剂的脂肪族,脂环族或芳族二异氰酸酯为1.5-3.0摩尔, 酮,醇,芳族化合物及其混合物。

    Coumarin-labeled nucleoside 5'-triphosphates
    5.
    发明授权
    Coumarin-labeled nucleoside 5'-triphosphates 失效
    香豆素标记核苷5'-三磷酸

    公开(公告)号:US5587472A

    公开(公告)日:1996-12-24

    申请号:US460027

    申请日:1995-06-02

    CPC分类号: C07H21/00

    摘要: A fluorescent label compound having the formulaA--B.sup.1 --B.sup.2 --B.sup.3 --CwhereinA represents the residue of a natural or synthetic nucleotide or nucleoside or a derivative thereof;B.sup.1 represents a divalent spacer radical or a single bond;B.sup.2 represents a divalent spacer radical;B.sup.3 represents a divalent spacer radical or a single bond; andC represents a coumarin radical having the formula ##STR1## in which R.sup.1 represents hydrogen or cyano;R.sup.2 represents phenyl or thiazolyl bonded in the 2-, 4- or 5-position, wherein the phenyl is unsubstituted or substituted by nitro, cyano, amino, --NH--C.sub.1-4 -alkyl, --(CH.sub.2).sub.1-4 --NH.sub.2, --(CH.sub.2).sub.1-4 --NH--(CH.sub.2).sub.1-3 --CH.sub.3, carboxy, C.sub.1-4 -alkoxycarbonyl, C.sub.1-4 -alkoxycarbonyloxy, hydroxy, C.sub.1-4 -alkylaminocarbonyl, or C.sub.1-4 -alkylcarbonylamino and either further unsubstituted or substituted by C.sub.1-4 -alkyl, fluorine, chlorine or bromine, and where the thiazolyl is unsubstituted or monosubstituted or disubstituted by chlorine, cyano, carboxyl, or C.sub.1-4 -alkoxycarbonyl, or the thiazolyl is fused in the 4- and 5-position with a benzene ring which is either unsubstituted or substituted by carboxyl, amino, or hydroxyl;R.sup.3 represents hydrogen, C.sub.1-4 -alkyl, C.sub.1-4 -alkoxycarbonyl-C.sub.1-4 -alkyl, or phenylsulphonyl, where the C.sub.1-4 -alkyl is unsubstituted or substituted by hydroxyl, amino, carboxyl, or C.sub.1-4 -alkoxycarbonyl, and where the phenylsulphonyl is unsubstituted or monosubstituted or disubstituted by chlorine, bromine, or C.sub.1-4 -alkyl;or where one of the radicals R.sup.2 or R.sup.3 denotes or is substituted by a primary or secondary amino group, hydroxyl, carboxyl, or C.sub.1-4 -alkoxycarbonyl, or can be converted into such a group by hydrolysis or hydrogenation.

    摘要翻译: 具有式A-B1-B2-B3-C的荧光标记化合物,其中A表示天然或合成的核苷酸或核苷或其衍生物的残基; B1代表二价间隔基团或单键; B2表示二价间隔基; B3表示二价间隔基或单键; 并且C表示具有式“IMAGE”的香豆素基团,其中R 1表示氢或氰基; 氰基,氨基,-NH-C 1-4 - 烷基, - (CH 2)1-4-NH 2,其中苯基未被取代或被硝基,氰基,氨基, , - (CH 2)1-4-NH-(CH 2)1-3 -CH 3,羧基,C 1-4 - 烷氧基羰基,C 1-4 - 烷氧基羰基氧基,羟基,C 1-4 - 烷基氨基羰基或C 1-4 - 烷基羰基氨基 进一步未取代或被C 1-4 - 烷基,氟,氯或溴取代,并且其中噻唑基未被取代或被氯,氰基,羧基或C 1-4 - 烷氧基羰基单取代或二取代,或噻唑基稠合在4- 和5-位,其中苯环是未取代的或被羧基,氨基或羟基取代; R 3表示氢,C 1-4 - 烷基,C 1-4 - 烷氧基羰基-C 1-4 - 烷基或苯基磺酰基,其中C 1-4 - 烷基未被取代或被羟基,氨基,羧基或C 1-4 - 烷氧基羰基取代, 并且其中苯基磺酰基未被取代或被氯,溴或C 1-4 - 烷基单取代或二取代; 或其中一个基团R 2或R 3表示或被伯或仲氨基,羟基,羧基或C 1-4 - 烷氧基羰基取代,或者可以通过水解或氢化转化为该基团。

    Phenyl substituted 2-thiazolyl tetrazolium salt indicators
    7.
    发明授权
    Phenyl substituted 2-thiazolyl tetrazolium salt indicators 失效
    苯基取代的2-噻唑基四唑盐指示剂

    公开(公告)号:US5290536A

    公开(公告)日:1994-03-01

    申请号:US974174

    申请日:1992-11-10

    摘要: Phenyl substituted 2-thiazolyl tetrazolium salt compounds characterized by a reflectance spectrum exhibiting an extended plateau above about 600-650 nm. Such compounds are useful as chromogenic indicators for reducing substances such as NADH. The reflectance plateau confers improved accuracy to analytical assays, particularly for the determination of analytes of medical diagnostic significance, in which a colorimetric response on a reagent carrier matrix is measured by reflectance.

    摘要翻译: 苯基取代的2-噻唑基四唑鎓盐化合物,其特征在于反射光谱表现出高于约600-650nm的扩展平台。 这些化合物可用作还原物质如NADH的显色指标。 反射平稳度使分析测定的准确性提高,特别是对于医学诊断意义的分析物的测定,其中通过反射率测量试剂载体基质上的比色响应。

    Substituted 2-thiazolyl tetrazolium salt indicators
    9.
    发明授权
    Substituted 2-thiazolyl tetrazolium salt indicators 失效
    取代的2-噻唑基四唑盐指示剂

    公开(公告)号:US5322680A

    公开(公告)日:1994-06-21

    申请号:US854773

    申请日:1992-04-02

    摘要: 2-Thiazolyl tetrazolium salt compounds characterized by a reflectance spectrum exhibiting an extended plateau above about 600-650 nm. Such compounds are useful as chromogenic indicators for reducing substances such as NADH. The reflectance plateau confers improved accuracy to analytical assays, particularly for the determination of analytes of medical diagnostic significance, in which a colorimetric response on a reagent carrier matrix is measured by reflectance.

    摘要翻译: 2-噻唑基四唑鎓盐化合物的特征在于反射光谱表现出高于约600-650nm的扩展平台。 这些化合物可用作还原物质如NADH的显色指标。 反射平稳度使分析测定的准确性提高,特别是对于医学诊断意义的分析物的测定,其中通过反射率测量试剂载体基质上的比色响应。