公开(公告)号：US20080032083A1

公开(公告)日：2008-02-07

申请号：US11579783

申请日：2005-05-12

申请人： James Serdy ,  Emanuel Sachs

发明人： James Serdy ,  Emanuel Sachs

IPC分类号： G03C1/00

CPC分类号： A61L27/56 ,  A61F2/28 ,  A61F2002/30062 ,  A61F2002/30224 ,  A61F2002/30225 ,  A61F2002/30785 ,  A61F2002/30985 ,  A61F2210/0004 ,  A61F2230/0069 ,  A61F2310/00293 ,  A61F2310/00353 ,  A61L27/54 ,  A61L2300/412 ,  A61L2300/434 ,  A61L2300/602 ,  B33Y10/00 ,  B33Y70/00 ,  B33Y80/00 ,  Y10T428/15 ,  Y10T428/24273 ,  Y10T428/31504

摘要： Methods of manufacturing an article use three-dimensional printing for a portion of the manufacturing. Three-dimensionally printing is conducted onto a powder bed which contains both organic-solvent-soluble, water-insoluble particles and water soluble, organic-solvent-insoluble particles. The water-soluble particles which may be selected for properties such as size and may include more than one substance. The organic-solvent-insoluble particles may further include at least one substantially insoluble substance such as a member of the calcium phosphate family. Printing may be done using an aqueous binder liquid. After removal of unbound powder, the preform may be exposed to the vapor of an organic solvent which causes the particles of organic-soluble-polymer to fuse to each other. This may further be followed by dissolving out the water-soluble particles, if such particles were present in the powder. Solvent vapor fusing together with the use of porogen particles may also be used in manufacturing methods other than 3DP. Rather than using organic solvent, heat responsive particles can be used, and can be filmed by elevated temperatures. Articles that may be produced by the described methods exhibit features such as a high porosity and an ability to undergo large deformations without breaking, and by at least partial springback from such deformation. The springback may be substantially instantaneous or may be time-dependent involving a time period of at least several seconds.

摘要翻译： 制造制品的方法在制造的一部分中使用三维印刷。 将三维打印进行到含有有机溶剂可溶性，水不溶性颗粒和水溶性有机溶剂不溶性颗粒的粉末床上。 可以选择尺寸等性质的水溶性颗粒，并且可以包括多于一种物质。 有机溶剂不溶性颗粒可以进一步包括至少一种基本上不溶的物质，例如磷酸钙族的成员。 可以使用水性粘合剂液体进行印刷。 在去除未结合的粉末之后，预制件可能暴露于有机溶剂的蒸气中，这导致有机可溶聚合物颗粒彼此熔合。 如果这种颗粒存在于粉末中，则可以进一步溶解水溶性颗粒。 与使用致孔剂颗粒一起使用的溶剂蒸汽熔融也可用于3DP以外的制造方法。 不使用有机溶剂，可以使用热响应颗粒，并且可以通过升高的温度进行成膜。 可以通过所述方法产生的制品表现出诸如高孔隙率和经受大变形而不断裂的能力以及至少部分回弹的特征。 回弹可以基本上是瞬时的，或者可以是时间依赖性的，涉及至少几秒的时间段。

公开(公告)号：US07824602B2

公开(公告)日：2010-11-02

申请号：US11433838

申请日：2006-05-12

申请人： Emanuel Sachs ,  Alaric Naiman ,  James Serdy

发明人： Emanuel Sachs ,  Alaric Naiman ,  James Serdy

IPC分类号： B28B3/20

CPC分类号： B28B3/20 ,  B28B11/243 ,  C04B35/632 ,  C04B35/634 ,  C04B2235/6021 ,  F41H5/0414 ,  F41H5/0492

摘要： The present invention relates to methods for the formation of ceramic bodies. Methods of the invention involve processing ceramic-forming compositions to form an integrally self-supporting or stabilized structure, which may then be sintered to give the full-density ceramic product. Methods of the invention may also involve densification of the ceramic body. In one set of embodiments, the volume of the integrally self-supporting structure is reduced by at least 20%. The present invention may produce ceramic bodies having greater strength and durability, since the ceramic-forming compositions may be low in viscosity and may be homogeneously blended, decreasing the possibility for defects.

摘要翻译： 本发明涉及形成陶瓷体的方法。 本发明的方法涉及加工陶瓷形成组合物以形成一体的自支撑或稳定的结构，然后可将其烧结以得到全密度陶瓷产品。 本发明的方法还可以包括陶瓷体的致密化。 在一组实施例中，整体自支撑结构的体积减少至少20％。 本发明可以制造具有更大强度和耐久性的陶瓷体，因为陶瓷形成组合物的粘度可以低，并且可以均匀混合，从而降低缺陷的可能性。

公开(公告)号：US20070228621A1

公开(公告)日：2007-10-04

申请号：US11433838

申请日：2006-05-12

申请人： Emanuel Sachs ,  Alaric Naiman ,  James Serdy

发明人： Emanuel Sachs ,  Alaric Naiman ,  James Serdy

IPC分类号： H05B6/00 ,  B28B3/00

CPC分类号： B28B3/20 ,  B28B11/243 ,  C04B35/632 ,  C04B35/634 ,  C04B2235/6021 ,  F41H5/0414 ,  F41H5/0492

摘要： The present invention relates to methods for the formation of ceramic bodies. Methods of the invention involve processing ceramic-forming compositions to form an integrally self-supporting or stabilized structure, which may then be sintered to give the full-density ceramic product. Methods of the invention may also involve densification of the ceramic body. In one set of embodiments, the volume of the integrally self-supporting structure is reduced by at least 20%. The present invention may produce ceramic bodies having greater strength and durability, since the ceramic-forming compositions may be low in viscosity and may be homogeneously blended, decreasing the possibility for defects.

摘要翻译： 本发明涉及形成陶瓷体的方法。 本发明的方法涉及加工陶瓷形成组合物以形成一体的自支撑或稳定的结构，然后可将其烧结以得到全密度陶瓷产品。 本发明的方法还可以包括陶瓷体的致密化。 在一组实施例中，整体自支撑结构的体积减少至少20％。 本发明可以制造具有更大强度和耐久性的陶瓷体，因为陶瓷形成组合物的粘度可以低，并且可以均匀混合，从而降低缺陷的可能性。

公开(公告)号：US20070009606A1

公开(公告)日：2007-01-11

申请号：US11127298

申请日：2005-05-12

申请人： James Serdy ,  Emanuel Sachs ,  Thomas West ,  Sunil Saini ,  Jie Cai ,  Andrea Caruso ,  John Sharobiem ,  Peter Materna

发明人： James Serdy ,  Emanuel Sachs ,  Thomas West ,  Sunil Saini ,  Jie Cai ,  Andrea Caruso ,  John Sharobiem ,  Peter Materna

IPC分类号： A61K9/50

CPC分类号： A61L27/56 ,  A61F2/28 ,  A61F2002/30062 ,  A61F2002/30224 ,  A61F2002/30225 ,  A61F2002/30785 ,  A61F2002/30985 ,  A61F2210/0004 ,  A61F2230/0069 ,  A61F2310/00293 ,  A61F2310/00353 ,  A61L27/54 ,  A61L2300/412 ,  A61L2300/434 ,  A61L2300/602 ,  B33Y10/00 ,  B33Y70/00 ,  B33Y80/00 ,  Y10T428/15 ,  Y10T428/24273 ,  Y10T428/31504

摘要： The invention includes biostructures which may be characterized as having substantially all of the organic-solvent-soluble material in the form of a network of irregularly shaped perforated films. The biostructure may further include particles of a substantially-insoluble material, which may be a member of the calcium phosphate family. The biostructure may be osteoconductive. The biostructure may further contain an Active Pharmaceutical Ingredient or other bioactive substance. The API may be a substance which stimulates the production of bone morphogenetic protein, such as Lovastatin or related substances, thereby making the biostructure effectively osteoinductive. One or more of the polymers may have a resorption rate in the human body such as to control the release of the API. Methods of manufacture are also disclosed.

摘要翻译： 本发明包括生物结构，其可以被表征为具有基本上所有有机溶剂可溶性材料形式的不规则形状的穿孔膜的网络。 生物结构可以进一步包括可以是磷酸钙家族成员的基本不溶物质的颗粒。 生物结构可能是骨传导的。 生物结构还可含有活性药物成分或其他生物活性物质。 API可以是刺激骨形态发生蛋白（例如洛伐他汀或相关物质）生产的物质，从​​而使生物结构有效地成骨诱导。 一种或多种聚合物可能在人体内具有吸收速率，以便控制API的释放。 还公开了制造方法。

公开(公告)号：US20090184382A1

公开(公告)日：2009-07-23

申请号：US12358755

申请日：2009-01-23

申请人： Katherine Hartman ,  James Serdy ,  Tonio Buonassisi

发明人： Katherine Hartman ,  James Serdy ,  Tonio Buonassisi

IPC分类号： H01L31/036 ,  H01L21/34 ,  H01L31/18

CPC分类号： C30B33/02 ,  C30B29/06

摘要： A crystalline material structure is provided. The crystalline material structure includes a semiconductor structure being annealed at temperatures above the brittle-to-ductile transition temperature of the semiconductor structure, and cooled in an approximately linear time-temperature profile down to approximately its respective transition temperature T0.

摘要翻译： 提供结晶材料结构。 结晶材料结构包括在高于半导体结构的脆性 - 延性转变温度的温度下退火的半导体结构，并且在近似线性时间 - 温度分布下冷却至大约其各自的转变温度T0。