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公开(公告)号：US08029745B2
公开(公告)日：2011-10-04
申请号：US12468417
申请日：2009-05-19
Applicant: Ian Hunter , Colin J. H. Brenan , Tanya S. Kanigan
Inventor： Ian Hunter , Colin J. H. Brenan , Tanya S. Kanigan
IPC: G01N1/10
CPC classification number: B01L3/0293 , B01F13/0071 , B01F13/0084 , B01J19/0046 , B01J2219/00283 , B01J2219/00317 , B01J2219/00319 , B01J2219/00351 , B01J2219/0036 , B01J2219/00369 , B01J2219/00373 , B01J2219/00387 , B01J2219/00389 , B01J2219/00423 , B01J2219/0043 , B01J2219/00479 , B01J2219/00495 , B01J2219/005 , B01J2219/00511 , B01J2219/00533 , B01J2219/00536 , B01J2219/00549 , B01J2219/00585 , B01J2219/00587 , B01J2219/00596 , B01J2219/00648 , B01J2219/00659 , B01J2219/00686 , B01L3/0262 , B01L3/5025 , B01L3/50255 , B01L3/5085 , B01L3/50857 , B01L99/00 , B01L2200/0642 , B01L2300/0819 , B01L2300/0845 , B01L2400/022 , C40B60/14 , C40B70/00 , G01N30/466 , G01N30/6095 , G01N30/82 , G01N35/00069 , G01N2035/00237 , G01N2035/1037 , Y10T83/0481 , Y10T436/11 , Y10T436/25 , Y10T436/25625 , Y10T436/2575
Abstract: Systems for filling sample array by droplet dragging are provided. One aspect of the invention provides an array filling system for filling a platen having a platen surface and an array of receptacles, the receptacles having an internal surface and the receptacles separated by the platen surface, the system comprising: a liquid transfer device capable of holding liquid; and a controller configured to position the liquid transfer device in proximity to the platen surface and to move the liquid transfer device across the surface and over the receptacles to be filled so as to cause sequential communication of liquid in the liquid transfer device with the interior surface of each receptacle.
Abstract translation: 提供了通过液滴拖动填充样品阵列的系统。 本发明的一个方面提供了一种阵列填充系统，用于填充具有压板表面和阵列的容器的压板，所述容器具有内表面和由压板表面分开的容器，所述系统包括：液体传送装置，其能够保持 液体; 以及控制器，其被配置为将液体转移装置定位在压板表面附近并且使液体转移装置跨过表面移动并在待填充的容器之上，以使液体转移装置中的液体与内表面顺序连通 的每个插座。
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公开(公告)号：US06893877B2
公开(公告)日：2005-05-17
申请号：US09850123
申请日：2001-05-07
Applicant: Ian Hunter , Colin J. H. Brenan , Tanya S. Kanigan
Inventor： Ian Hunter , Colin J. H. Brenan , Tanya S. Kanigan
IPC: G01N35/02 , B01F13/00 , B01J4/02 , B01J19/00 , B01L3/00 , B01L3/02 , B01L99/00 , B81B1/00 , B81C99/00 , C12M1/00 , C40B60/14 , C40B70/00 , G01N30/46 , G01N30/60 , G01N30/82 , G01N35/00 , G01N35/10 , G01N1/10 , G01N21/03
CPC classification number: B01L3/0293 , B01F13/0071 , B01F13/0084 , B01J19/0046 , B01J2219/00283 , B01J2219/00317 , B01J2219/00319 , B01J2219/00351 , B01J2219/0036 , B01J2219/00369 , B01J2219/00373 , B01J2219/00387 , B01J2219/00389 , B01J2219/00423 , B01J2219/0043 , B01J2219/00479 , B01J2219/00495 , B01J2219/005 , B01J2219/00511 , B01J2219/00533 , B01J2219/00536 , B01J2219/00549 , B01J2219/00585 , B01J2219/00587 , B01J2219/00596 , B01J2219/00648 , B01J2219/00659 , B01J2219/00686 , B01L3/0262 , B01L3/5025 , B01L3/50255 , B01L3/5085 , B01L3/50857 , B01L99/00 , B01L2200/0642 , B01L2300/0819 , B01L2300/0845 , B01L2400/022 , C40B60/14 , C40B70/00 , G01N30/466 , G01N30/6095 , G01N30/82 , G01N35/00069 , G01N2035/00237 , G01N2035/1037 , Y10T83/0481 , Y10T436/11 , Y10T436/25 , Y10T436/25625 , Y10T436/2575
Abstract: Methods for manufacturing and using an apparatus for manipulating and analyzing a large number of microscopic samples of a liquid or materials, including cells, in liquid suspension. Parallel through-holes are formed in a platen and loaded with a liquid. Loading may be performed in such a way as to create a gradient, with respect to the position of the through-holes, of the concentration of a particular substance or of another quantity. Mixing of the contents of through-holes may be obtained by bringing filled microwell arrays into contact with each other with registration of individual through-holes.
Abstract translation: 用于制造和使用用于操纵和分析液体或包括细胞在内的液体悬浮液的大量微观样品的装置的方法。 平行的通孔形成在压板中并装载液体。 可以以相对于通孔的位置产生特定物质的浓度或另一数量的浓度的梯度来进行装载。 可以通过使填充的微孔阵列通过单独的通孔对准而彼此接触来获得通孔内容物的混合。
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公开(公告)号：US07547556B2
公开(公告)日：2009-06-16
申请号：US10958969
申请日：2004-10-05
Applicant: Ian Hunter , Colin J. H. Brenan , Tanya S. Kanigan
Inventor： Ian Hunter , Colin J. H. Brenan , Tanya S. Kanigan
IPC: G01N1/10
CPC classification number: B01L3/0293 , B01F13/0071 , B01F13/0084 , B01J19/0046 , B01J2219/00283 , B01J2219/00317 , B01J2219/00319 , B01J2219/00351 , B01J2219/0036 , B01J2219/00369 , B01J2219/00373 , B01J2219/00387 , B01J2219/00389 , B01J2219/00423 , B01J2219/0043 , B01J2219/00479 , B01J2219/00495 , B01J2219/005 , B01J2219/00511 , B01J2219/00533 , B01J2219/00536 , B01J2219/00549 , B01J2219/00585 , B01J2219/00587 , B01J2219/00596 , B01J2219/00648 , B01J2219/00659 , B01J2219/00686 , B01L3/0262 , B01L3/5025 , B01L3/50255 , B01L3/5085 , B01L3/50857 , B01L99/00 , B01L2200/0642 , B01L2300/0819 , B01L2300/0845 , B01L2400/022 , C40B60/14 , C40B70/00 , G01N30/466 , G01N30/6095 , G01N30/82 , G01N35/00069 , G01N2035/00237 , G01N2035/1037 , Y10T83/0481 , Y10T436/11 , Y10T436/25 , Y10T436/25625 , Y10T436/2575
Abstract: A method and an array filling system for loading a plurality of disparate sample containers, the sample containers comprising an integral structure. Each receptacle is characterized by a hydrophilic surface, and the receptacles are separated by a hydrophobic surface. The system has a liquid transfer device capable of holding liquid and adapted for motion to cause sequential communication of liquid held in the liquid transfer device with successive receptacles of the array by dragging the liquid across the hydrophobic surface.
Abstract translation: 一种用于装载多个不同样本容器的方法和阵列填充系统，所述样本容器包括整体结构。 每个容器的特征在于亲水表面，并且容器由疏水表面分开。 该系统具有能够保持液体并适于运动的液体转移装置，以通过将液体拖过疏水表面而使保持在液体转移装置中的液体与阵列的连续容器顺序连通。
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公开(公告)号：US20090258797A1
公开(公告)日：2009-10-15
申请号：US12468417
申请日：2009-05-19
Applicant: Ian Hunter , Colin J.H. Brenan , Tanya S. Kanigan
Inventor： Ian Hunter , Colin J.H. Brenan , Tanya S. Kanigan
IPC: C40B60/14
CPC classification number: B01L3/0293 , B01F13/0071 , B01F13/0084 , B01J19/0046 , B01J2219/00283 , B01J2219/00317 , B01J2219/00319 , B01J2219/00351 , B01J2219/0036 , B01J2219/00369 , B01J2219/00373 , B01J2219/00387 , B01J2219/00389 , B01J2219/00423 , B01J2219/0043 , B01J2219/00479 , B01J2219/00495 , B01J2219/005 , B01J2219/00511 , B01J2219/00533 , B01J2219/00536 , B01J2219/00549 , B01J2219/00585 , B01J2219/00587 , B01J2219/00596 , B01J2219/00648 , B01J2219/00659 , B01J2219/00686 , B01L3/0262 , B01L3/5025 , B01L3/50255 , B01L3/5085 , B01L3/50857 , B01L99/00 , B01L2200/0642 , B01L2300/0819 , B01L2300/0845 , B01L2400/022 , C40B60/14 , C40B70/00 , G01N30/466 , G01N30/6095 , G01N30/82 , G01N35/00069 , G01N2035/00237 , G01N2035/1037 , Y10T83/0481 , Y10T436/11 , Y10T436/25 , Y10T436/25625 , Y10T436/2575
Abstract: Systems for filling sample array by droplet dragging are provided. One aspect of the invention provides an array filling system for filling a platen having a platen surface and an array of receptacles, the receptacles having an internal surface and the receptacles separated by the platen surface, the system comprising: a liquid transfer device capable of holding liquid; and a controller configured to position the liquid transfer device in proximity to the platen surface and to move the liquid transfer device across the surface and over the receptacles to be filled so as to cause sequential communication of liquid in the liquid transfer device with the interior surface of each receptacle.
Abstract translation: 提供了通过液滴拖动填充样品阵列的系统。 本发明的一个方面提供了一种阵列填充系统，用于填充具有压板表面和阵列的容器的压板，所述容器具有内表面和由压板表面分开的容器，所述系统包括：液体传送装置，其能够保持 液体; 以及控制器，其被配置为将液体转移装置定位在压板表面附近并且使液体转移装置跨过表面移动并在待填充的容器之上，以使液体转移装置中的液体与内表面顺序连通 的每个插座。
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公开(公告)号：US20170028376A9
公开(公告)日：2017-02-02
申请号：US14582122
申请日：2014-12-23
Applicant: Ian Hunter , Colin J.H. Brenan , Tanya S. Kanigan
Inventor： Ian Hunter , Colin J.H. Brenan , Tanya S. Kanigan
CPC classification number: B01J19/0046 , B01F13/0071 , B01F13/0084 , B01J2219/00313 , B01J2219/00317 , B01J2219/00351 , B01J2219/00533 , B01J2219/00536 , B01J2219/00549 , B01J2219/00585 , B01J2219/00599 , B01L3/5025 , B01L3/5085 , B01L3/50857 , B01L2200/0642 , C12Q1/34 , C40B60/14 , C40B70/00 , G01N21/75 , G01N35/00069 , G01N35/1002 , G01N2035/00237 , Y10T436/11 , Y10T436/112499 , Y10T436/25
Abstract: A method and an array filling system for loading a plurality of disparate sample containers, the sample containers comprising an integral structure. Each receptacle is characterized by a hydrophilic surface,, and the receptacles are separated by a hydrophobic surface. The system has a liquid transfer device capable of holding liquid and adapted for motion to cause sequential communication of liquid held in the liquid transfer device with successive receptacles of the array by dragging the liquid across the hydrophobic surface.
Abstract translation: 一种用于装载多个不同样本容器的方法和阵列填充系统，所述样本容器包括整体结构。 每个容器的特征在于亲水表面，并且容器由疏水表面分开。 该系统具有能够保持液体并适于运动的液体转移装置，以通过将液体拖过疏水表面而使保持在液体转移装置中的液体与阵列的连续容器顺序连通。
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Patent Agency Ranking
公开(公告)号：US20110319300A1
公开(公告)日：2011-12-29
申请号：US13229208
申请日：2011-09-09
Applicant: Ian Hunter , Colin J.H. Brenan , Tanya S. Kanigan
Inventor： Ian Hunter , Colin J.H. Brenan , Tanya S. Kanigan
CPC classification number: B01L3/0293 , B01F13/0071 , B01F13/0084 , B01J19/0046 , B01J2219/00283 , B01J2219/00317 , B01J2219/00319 , B01J2219/00351 , B01J2219/0036 , B01J2219/00369 , B01J2219/00373 , B01J2219/00387 , B01J2219/00389 , B01J2219/00423 , B01J2219/0043 , B01J2219/00479 , B01J2219/00495 , B01J2219/005 , B01J2219/00511 , B01J2219/00533 , B01J2219/00536 , B01J2219/00549 , B01J2219/00585 , B01J2219/00587 , B01J2219/00596 , B01J2219/00648 , B01J2219/00659 , B01J2219/00686 , B01L3/0262 , B01L3/5025 , B01L3/50255 , B01L3/5085 , B01L3/50857 , B01L9/523 , B01L2200/0642 , B01L2300/0819 , B01L2300/0829 , B01L2300/0845 , B01L2400/022 , C40B60/14 , C40B70/00 , G01N30/466 , G01N30/6095 , G01N30/82 , G01N35/00069 , G01N2035/00237 , G01N2035/1037 , Y10T83/0481 , Y10T436/11 , Y10T436/25 , Y10T436/25625 , Y10T436/2575
Abstract: A method and an array filling system for loading a plurality of disparate sample containers, the sample containers comprising an integral structure. Each receptacle is characterized by a hydrophilic surface, and the receptacles are separated by a hydrophobic surface. The system has a liquid transfer device capable of holding liquid and adapted for motion to cause sequential communication of liquid held in the liquid transfer device with successive receptacles of the array by dragging the liquid across the hydrophobic surface.
Abstract translation: 一种用于装载多个不同样本容器的方法和阵列填充系统，所述样本容器包括整体结构。 每个容器的特征在于亲水表面，并且容器由疏水表面分开。 该系统具有能够保持液体并适于运动的液体转移装置，以通过将液体拖过疏水表面而使保持在液体转移装置中的液体与阵列的连续容器顺序连通。
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公开(公告)号：US20150298089A1
公开(公告)日：2015-10-22
申请号：US14582122
申请日：2014-12-23
Applicant: Ian Hunter , Colin J.H. Brenan , Tanya S. Kanigan
Inventor： Ian Hunter , Colin J.H. Brenan , Tanya S. Kanigan
CPC classification number: B01J19/0046 , B01F13/0071 , B01F13/0084 , B01J2219/00313 , B01J2219/00317 , B01J2219/00351 , B01J2219/00533 , B01J2219/00536 , B01J2219/00549 , B01J2219/00585 , B01J2219/00599 , B01L3/5025 , B01L3/5085 , B01L3/50857 , B01L2200/0642 , C12Q1/34 , C40B60/14 , C40B70/00 , G01N21/75 , G01N35/00069 , G01N35/1002 , G01N2035/00237 , Y10T436/11 , Y10T436/112499 , Y10T436/25
Abstract: A method and an array filling system for loading a plurality of disparate sample containers, the sample containers comprising an integral structure. Each receptacle is characterized by a hydrophilic surface,, and the receptacles are separated by a hydrophobic surface. The system has a liquid transfer device capable of holding liquid and adapted for motion to cause sequential communication of liquid held in the liquid transfer device with successive receptacles of the array by dragging the liquid across the hydrophobic surface.
Abstract translation: 一种用于装载多个不同样本容器的方法和阵列填充系统，所述样本容器包括整体结构。 每个容器的特征在于亲水表面，并且容器由疏水表面分开。 该系统具有能够保持液体并适于运动的液体转移装置，以通过将液体拖过疏水表面而使保持在液体转移装置中的液体与阵列的连续容器顺序连通。
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8.发明申请公开(公告)号：US20070169333A1
公开(公告)日：2007-07-26
申请号：US11723999
申请日：2007-03-23
Applicant: John Donoghue , Nicholas Hatsopoulos , Sylvain Martel , Timothy Fofonoff , Robert Dyer , Ian Hunter
Inventor： John Donoghue , Nicholas Hatsopoulos , Sylvain Martel , Timothy Fofonoff , Robert Dyer , Ian Hunter
CPC classification number: A61B5/685 , A61B5/04001 , A61B5/076 , A61B2562/125 , Y10T29/49
Abstract: A brain implant system consistent with embodiments of the present invention includes an electrode array having a plurality of electrodes for sensing neuron signals. A method for manufacturing the electrode array includes machining a piece of an electrically conductive substance to create a plurality of electrodes extending from a base member. Each electrode also has a corresponding base section. A nonconductive layer is provided around at least a portion of the base section of each electrode to support the plurality of electrodes. The base section of the electrodes are then cut to separate the base member from the plurality of electrodes supported by the nonconductive support layer. The present invention also includes a complete brain implant system using the above electrode array.
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公开(公告)号：US20060058607A1
公开(公告)日：2006-03-16
申请号：US11006359
申请日：2004-12-07
Applicant: Michael Garcia-Webb , Ian Hunter , Andrew Taberner
Inventor： Michael Garcia-Webb , Ian Hunter , Andrew Taberner
IPC: A61B5/05
CPC classification number: G01N3/38 , G01N2203/0023 , G01N2203/0051 , G01N2203/0089 , G01N2203/0222 , G01N2203/0286
Abstract: An electromagnetic apparatus, comprises a conductive loop comprising two parallel conductive legs joined at a free end by a sample contacting member and a magnetic circuit that imposes a magnetic field in opposite directions across the respective legs. A method of mechanically characterizing a sample, comprises imposing a magnetic field in opposite directions in each of two parallel conductive legs of a conductive loop, the legs joined at a free end by a sample contacting member.
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公开(公告)号：US20120023723A1
公开(公告)日：2012-02-02
申请号：US13260105
申请日：2010-03-31
Applicant: Philip Alfred Barker , Graham Anthony Laidler , Christopher Nigel Munnings , Ian Hunter , Keith Eric Nolde
Inventor： Philip Alfred Barker , Graham Anthony Laidler , Christopher Nigel Munnings , Ian Hunter , Keith Eric Nolde
CPC classification number: H02G1/086 , G02B6/4463 , G02B6/4464 , Y10T29/49771 , Y10T29/4978 , Y10T29/53022 , Y10T29/53039 , Y10T29/53061 , Y10T29/53526
Abstract: Apparatus for installing a cable into a tube with the assistance of a fluid drag acting on the cable within the tube, the apparatus including: driving means comprising a driving surface arranged to contact the cable substantially along the full driving surface length, for driving the cable into the tube, first measurement means for obtaining a first value indicative of a rate at which the installation means is driving the cable into the tube, second measurement means for obtaining a second value indicative of a rate at which the cable is travelling through the apparatus, a processor for detecting when the first value exceeds the second value, and for reducing the rate at which the installation means is driving the cable into the tube for the duration when the first value exceeds the second value.
Abstract translation: 用于借助于作用在管内的电缆上的流体阻力将电缆安装到管中的装置，该装置包括：驱动装置，包括驱动表面，驱动表面布置成基本沿着整个驱动表面长度接触电缆，用于驱动电缆 进入管中的第一测量装置，用于获得指示安装装置将电缆驱动到管中的速率的第一值的第一测量装置，用于获得指示电缆行进通过装置的速率的第二值的第二测量装置 ，用于检测所述第一值何时超过所述第二值的处理器，以及用于在所述第一值超过所述第二值的持续时间内降低所述安装装置将所述电缆驱动到所述管中的速率。
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