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公开(公告)号:US09632091B2
公开(公告)日:2017-04-25
申请号:US14919388
申请日:2015-10-21
Applicant: Genentech, Inc.
Inventor: Siminder Atwal , Jo-Anne Hongo , Mark Lackner , Elizabeth Punnoose , Bonnee Rubinfeld , Rajesh Vij
IPC: G01N33/53 , G01N33/574 , C07K16/30 , C12N5/09
CPC classification number: G01N33/57434 , C07K16/3069 , C12N5/0693 , C12Y116/01 , C12Y301/03048 , G01N33/57492 , G01N2333/4742 , G01N2333/70596 , G01N2333/90287 , G01N2333/916 , G01N2800/52
Abstract: The invention provides methods for diagnosing prostate cancer. The invention also provides novel anti-STEAP-1 antibodies and uses thereof.
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公开(公告)号:US09945858B2
公开(公告)日:2018-04-17
申请号:US15065615
申请日:2016-03-09
Applicant: Genentech, Inc.
Inventor: Feny Gunawan , Yi-Chun Hsiao , Denise C. Krawitz , Margaret S. Lin , Martin Vanderlaan , Rajesh Vij , Inn H. Yuk , Judith Zhu-Shimoni
IPC: G01N33/577 , G01N33/573 , C07K16/40
CPC classification number: G01N33/573 , C07K16/40 , C07K2317/33 , C07K2317/565 , G01N33/577 , G01N2333/918 , G01N2333/92 , G01N2500/10
Abstract: Monoclonal and polyclonal antibodies that bind hamster phospholipase B-like 2 are provided. Also provided are methods for detecting and quantifying hamster phospholipase B-like 2, for example, in recombinant polypeptide preparations, as well as kits for carrying out such methods. Methods of screening or selecting host cell lines or recombinant polypeptide-expressing cell lines that express low levels of hamster phospholipase B-like 2 are also provided.
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公开(公告)号:US09175089B2
公开(公告)日:2015-11-03
申请号:US13853620
申请日:2013-03-29
Applicant: GENENTECH INC.
Inventor: Jo-Anne Hongo , Weiguang Mao , Paul Polakis , Andrew Polson , Rajesh Vij , Yan Wu , Wei-Ching Liang
CPC classification number: C07K16/28 , A61K47/6803 , A61K47/6809 , A61K47/6817 , A61K47/6849 , A61K47/6859 , A61K47/6863 , A61K2039/505 , C07K16/30 , C07K16/3046 , C07K2317/24 , C07K2317/33 , C07K2317/73 , C07K2317/92 , G01N33/6893
Abstract: The invention provides anti-LgR5 antibodies and immunoconjugates and methods of using the same.
Abstract translation: 本发明提供抗LgR5抗体和免疫缀合物及其使用方法。
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公开(公告)号:US20130266973A1
公开(公告)日:2013-10-10
申请号:US13841691
申请日:2013-03-15
Applicant: GENENTECH, INC.
Inventor: Jo-Anne Hongo , Yanhong Li , Luna Liu , John Lowe , Mauricio Maia , Rajesh Vij , Terence Wong , Keyang XU
IPC: C07K16/42
CPC classification number: C07K16/4216 , C07K16/088 , C07K2317/56 , C07K2317/92 , G01N33/56994 , G01N33/686 , G01N2333/045 , G01N2469/20
Abstract: The invention provides anti-idiotypic HCMV antibodies as well as methods of using the same.
Abstract translation: 本发明提供抗独特型HCMV抗体及其使用方法。
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公开(公告)号:US11519912B2
公开(公告)日:2022-12-06
申请号:US15914099
申请日:2018-03-07
Applicant: Genentech, Inc.
Inventor: Feny Gunawan , Yi-Chun Hsiao , Denise C. Krawitz , Margaret S. Lin , Martin Vanderlaan , Rajesh Vij , Inn H. Yuk , Judith Zhu-Shimoni
IPC: G01N33/577 , G01N33/573 , C07K16/40
Abstract: Monoclonal and polyclonal antibodies that bind hamster phospholipase B-like 2 are provided. Also provided are methods for detecting and quantifying hamster phospholipase B-like 2, for example, in recombinant polypeptide preparations, as well as kits for carrying out such methods. Methods of screening or selecting host cell lines or recombinant polypeptide-expressing cell lines that express low levels of hamster phospholipase B-like 2 are also provided.
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公开(公告)号:US20180364235A1
公开(公告)日:2018-12-20
申请号:US15914094
申请日:2018-03-07
Applicant: Genentech, Inc.
Inventor: Feny Gunawan , Yi-Chun Hsiao , Denise C. Krawitz , Margaret S. Lin , Martin Vanderlaan , Rajesh Vij , Inn H. Yuk , Judith Zhu-Shimoni
IPC: G01N33/573 , G01N33/577 , C07K16/40
Abstract: Monoclonal and polyclonal antibodies that bind hamster phospholipase B-like 2 are provided. Also provided are methods for detecting and quantifying hamster phospholipase B-like 2, for example, in recombinant polypeptide preparations, as well as kits for carrying out such methods. Methods of screening or selecting host cell lines or recombinant polypeptide-expressing cell lines that express low levels of hamster phospholipase B-like 2 are also provided.
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公开(公告)号:US20150376265A1
公开(公告)日:2015-12-31
申请号:US14577991
申请日:2014-12-19
Applicant: Genentech, Inc.
Inventor: Xiaocheng Chen , Mark Dennis , Becket L. Feierbach , Ashley Fouts , Isidro Hotzel , Bing Li , Jo-Anne S. Hongo , Rajesh Vij
CPC classification number: C07K16/088 , A61K39/42 , A61K45/06 , A61K2039/505 , A61K2039/507 , C07K2317/24 , C07K2317/30 , C07K2317/51 , C07K2317/515 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/76 , C07K2317/92
Abstract: The invention provides compositions comprising anti-gH antibodies and anti-Complex I antibodies as well as methods of using the same.
Abstract translation: 本发明提供了包含抗-GH抗体和抗复合物I抗体的组合物以及使用该组合物的方法。
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公开(公告)号:US20130336885A1
公开(公告)日:2013-12-19
申请号:US13853620
申请日:2013-03-29
Applicant: GENENTECH INC.
Inventor: Jo-Anne Hongo , Weiguang Mao , Paul Polakis , Andrew Polson , Rajesh Vij , Yan Wu , Wei-Ching Liang
IPC: C07K16/30 , G01N33/68 , A61K51/10 , A61K39/395
CPC classification number: C07K16/28 , A61K47/6803 , A61K47/6809 , A61K47/6817 , A61K47/6849 , A61K47/6859 , A61K47/6863 , A61K2039/505 , C07K16/30 , C07K16/3046 , C07K2317/24 , C07K2317/33 , C07K2317/73 , C07K2317/92 , G01N33/6893
Abstract: The invention provides anti-LgR5 antibodies and immunoconjugates and methods of using the same.
Abstract translation: 本发明提供抗LgR5抗体和免疫缀合物及其使用方法。
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公开(公告)号:US20160102146A1
公开(公告)日:2016-04-14
申请号:US14856731
申请日:2015-09-17
Applicant: GENENTECH, INC.
Inventor: Jo-Anne Hongo , Weiguang Mao , Paul Polakis , Andrew Polson , Rajesh Vij , Yan Wu , Wei-Ching Liang
IPC: C07K16/28
CPC classification number: C07K16/28 , A61K47/6803 , A61K47/6809 , A61K47/6817 , A61K47/6849 , A61K47/6859 , A61K47/6863 , A61K2039/505 , C07K16/30 , C07K16/3046 , C07K2317/24 , C07K2317/33 , C07K2317/73 , C07K2317/92 , G01N33/6893
Abstract: The invention provides anti-LgR5 antibodies and immunoconjugates and methods of using the same.
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公开(公告)号:US20160002355A1
公开(公告)日:2016-01-07
申请号:US14860344
申请日:2015-09-21
Applicant: Genentech, Inc.
Inventor: Jo-Anne Hongo , Yanhong Li , Luna Liu , John Lowe , Mauricio Maia , Rajesh Vij , Terence Wong , Keyang Xu
CPC classification number: C07K16/4216 , C07K16/088 , C07K2317/56 , C07K2317/92 , G01N33/56994 , G01N33/686 , G01N2333/045 , G01N2469/20
Abstract: The invention provides anti-idiotypic HCMV antibodies as well as methods of using the same.
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