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公开(公告)号:US20230383008A1
公开(公告)日:2023-11-30
申请号:US18048763
申请日:2022-10-21
Applicant: Genentech, Inc.
Inventor: Robert F. KELLEY , Daniel K. Kirchhofer , Joyce Lai , Chingwei V. Lee , Wei-Ching Liang , Michael T. Lipari , Kelly M. Loyet , Tao Sai , Menno Van Lookeren Campagne , Yan Wu , Germaine Fuh
IPC: C07K16/40 , A61K39/395
CPC classification number: C07K16/40 , A61K39/3955 , C07K2317/24 , C07K2317/34 , C07K2317/76 , C07K2317/92 , C07K2317/94 , A61K2039/507
Abstract: The present invention provides anti-HtrA1 antibodies (including bispecific anti-HtrA1 anti-Factor D antibodies) and methods of making and using the same, for example, in methods of treating HtrA1-associated disorders, ocular disorders, and/or complement-associated disorders.
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公开(公告)号:US11512143B2
公开(公告)日:2022-11-29
申请号:US16543818
申请日:2019-08-19
Applicant: Genentech, Inc.
Inventor: Robert F. Kelley , Daniel K. Kirchhofer , Joyce Lai , Chingwei V. Lee , Wei-Ching Liang , Michael T. Lipari , Kelly M. Loyet , Tao Sai , Menno Van Lookeren Campagne , Yan Wu , Germaine Fuh
IPC: C07K16/40 , A61K39/395 , A61K39/00
Abstract: The present invention provides anti-HtrA1 antibodies (including bispecific anti-HtrA1 anti-Factor D antibodies) and methods of making and using the same, for example, in methods of treating HtrA1-associated disorders, ocular disorders, and/or complement-associated disorders.
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公开(公告)号:US20190248903A1
公开(公告)日:2019-08-15
申请号:US16250398
申请日:2019-01-17
Applicant: Genentech, Inc.
Inventor: Bing ZHENG , Andrew Polson , Cecilia Chiu , Wei-Ching Liang , Yan Wu
IPC: C07K16/28 , A61K31/5517 , A61K47/68 , A61K51/10 , A61K31/706 , C07K16/30 , G01N33/574
CPC classification number: C07K16/2851 , A61K31/5517 , A61K31/706 , A61K47/68 , A61K47/6817 , A61K47/6867 , A61K47/6889 , A61K51/1069 , A61K51/1093 , C07K16/3061 , C07K2317/14 , C07K2317/24 , C07K2317/33 , C07K2317/34 , C07K2317/52 , C07K2317/76 , C07K2317/77 , C07K2317/92 , C07K2317/94 , G01N33/57426 , G01N2333/7056
Abstract: The invention provides anti-CLL-1 antibodies and immunoconjugates and methods of using the same.
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公开(公告)号:US10150813B2
公开(公告)日:2018-12-11
申请号:US14773334
申请日:2014-03-13
Applicant: Genentech, Inc.
Inventor: Steven R. Leong , Andrew Polson , Paul Polakis , Yan Wu , Wei-Ching Liang , Ron Firestein
IPC: C07K16/28 , A61K39/395 , A61K38/08 , A61K51/10 , C07K16/30 , G01N33/569 , A61K47/65 , A61K47/68 , A61K39/00
Abstract: The disclosure provides anti-B7-H4 antibodies and immunoconjugates and methods of using the same.
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公开(公告)号:US10047158B2
公开(公告)日:2018-08-14
申请号:US15895741
申请日:2018-02-13
Applicant: Genentech, Inc.
Inventor: Jane L. Grogan , Robert J. Johnston , Yan Wu , Wei-Ching Liang , Patrick Lupardus , Mahesh Yadav , Dhaya Seshasayee , Meredith Hazen
CPC classification number: C07K16/28 , A61K38/177 , A61K39/39558 , A61K45/06 , A61K2039/505 , A61K2039/507 , C07K16/2818 , C07K16/2827 , C07K16/2878 , C07K16/3061 , C07K2317/24 , C07K2317/33 , C07K2317/34 , C07K2317/55 , C07K2317/56 , C07K2317/567 , C07K2317/70 , C07K2317/75 , C07K2317/76 , C07K2317/90 , C07K2317/92 , C07K2317/94 , Y02A50/466
Abstract: The invention provides anti-TIGIT (T-cell immunoreceptor with Ig and ITIM domains) antibodies and methods of using the same.
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公开(公告)号:US20180009894A1
公开(公告)日:2018-01-11
申请号:US15657472
申请日:2017-07-24
Applicant: Genentech, Inc.
Inventor: Bing Zheng , Andrew Polson , Cecilia Chiu , Wei-Ching Liang , Yan Wu
IPC: C07K16/28 , C07K16/30 , A61K31/706 , A61K51/10 , G01N33/574 , A61K31/5517
CPC classification number: C07K16/2851 , A61K31/5517 , A61K31/706 , A61K47/68 , A61K47/6817 , A61K47/6867 , A61K47/6889 , A61K51/1069 , A61K51/1093 , C07K16/3061 , C07K2317/14 , C07K2317/24 , C07K2317/33 , C07K2317/34 , C07K2317/52 , C07K2317/76 , C07K2317/77 , C07K2317/92 , C07K2317/94 , G01N33/57426 , G01N2333/7056
Abstract: The invention provides anti-CLL-1 antibodies and immunoconjugates and methods of using the same.
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公开(公告)号:US09562099B2
公开(公告)日:2017-02-07
申请号:US14207878
申请日:2014-03-13
Applicant: Genentech, Inc.
Inventor: Steven R. Leong , Andrew Polson , Paul Polakis , Yan Wu , Wei-Ching Liang , Ron Firestein
IPC: C07K16/28 , A61K47/48 , A61K45/06 , G01N33/574 , A61K51/10 , A61K39/395 , A61K39/00
CPC classification number: C07K16/3015 , A61K31/5377 , A61K31/5517 , A61K39/3955 , A61K45/06 , A61K47/6803 , A61K47/6849 , A61K51/1027 , A61K2039/505 , C07K16/2827 , C07K16/3069 , C07K2317/24 , C07K2317/33 , C07K2317/34 , C07K2317/41 , C07K2317/567 , C07K2317/77 , C07K2317/92 , G01N33/57492 , A61K2300/00
Abstract: The invention provides anti-B7-H4 antibodies and immunoconjugates and methods of using the same.
Abstract translation: 本发明提供抗B7-H4抗体和免疫缀合物及其使用方法。
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公开(公告)号:US20170002074A1
公开(公告)日:2017-01-05
申请号:US15171128
申请日:2016-06-02
Applicant: GENENTECH, INC.
Inventor: Shang-Fan Yu , Wei-Ching Liang , Yan Wu , Steven Leong , Andrew Polson
IPC: C07K16/28 , G01N33/574 , A61K47/48
CPC classification number: C07K16/2803 , A61K47/6809 , A61K47/6849 , A61K2039/505 , C07K2317/33 , C07K2317/73 , C07K2317/77 , C07K2317/92 , G01N33/57492 , G01N2333/70596 , G01N2458/00
Abstract: The invention provides anti-CD33 antibodies and immunoconjugates and methods of using the same.
Abstract translation: 本发明提供抗CD33抗体和免疫缀合物及其使用方法。
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9.Inhibition of tumor metastasis by anti-neuropilin 2 antibodies 有权
Title translation: 抗神经丝氨酸2抗体抑制肿瘤转移公开(公告)号:US08920805B2
公开(公告)日:2014-12-30
申请号:US13915363
申请日:2013-06-11
Applicant: Genentech, Inc.
Inventor: Yan Wu , Wei-Ching Liang , Ryan Jefferson Watts , Anil Durgadas
IPC: A61K39/395 , C07K16/28 , C07K16/22 , A61K39/00
CPC classification number: C07K16/2863 , A61K2039/505 , C07K16/22 , C07K2317/21 , C07K2317/31 , C07K2317/622 , C07K2317/76 , C07K2317/92
Abstract: The invention provides Nrp2 antagonists, such as anti-Nrp2 antibodies, and their use in the prevention and treatment of tumor metastasis.
Abstract translation: 本发明提供Nrp2拮抗剂,例如抗Nrp2抗体,以及它们在预防和治疗肿瘤转移中的用途。
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公开(公告)号:US20130336885A1
公开(公告)日:2013-12-19
申请号:US13853620
申请日:2013-03-29
Applicant: GENENTECH INC.
Inventor: Jo-Anne Hongo , Weiguang Mao , Paul Polakis , Andrew Polson , Rajesh Vij , Yan Wu , Wei-Ching Liang
IPC: C07K16/30 , G01N33/68 , A61K51/10 , A61K39/395
CPC classification number: C07K16/28 , A61K47/6803 , A61K47/6809 , A61K47/6817 , A61K47/6849 , A61K47/6859 , A61K47/6863 , A61K2039/505 , C07K16/30 , C07K16/3046 , C07K2317/24 , C07K2317/33 , C07K2317/73 , C07K2317/92 , G01N33/6893
Abstract: The invention provides anti-LgR5 antibodies and immunoconjugates and methods of using the same.
Abstract translation: 本发明提供抗LgR5抗体和免疫缀合物及其使用方法。
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